colorectal cancer

Summary
Definition
A large intestine cancer that is located_in the colon and/or located_in the rectum.
Super Class
large intestine cancer
Disease Ontology
DOID:9256
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
MGI genotype (from TogoID)
WikiPathways (from TogoID)
Related Genes
Displaying entries 1 - 10 of 84 in total
Gene ID Gene Symbol Description Source
25 ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
207 AKT1 AKT serine/threonine kinase 1
324 APC APC regulator of WNT signaling pathway
472 ATM ATM serine/threonine kinase
581 BAX BCL2 associated X, apoptosis regulator
672 BRCA1 BRCA1 DNA repair associated
699 BUB1 BUB1 mitotic checkpoint serine/threonine kinase
701 BUB1B BUB1 mitotic checkpoint serine/threonine kinase B
842 CASP9 caspase 9
1066 CES1 carboxylesterase 1
Displaying 1 entry
Gene ID Gene Symbol Description Source
20848 Stat3 signal transducer and activator of transcription 3
Displaying 1 entry
Gene ID Gene Symbol Description Source
850438 ERS1 cystinosin-like protein ERS1
The Human Phenotype Ontology
Displaying all 7 entries
HPO ID HPO Term
HP:0005584 Renal cell carcinoma
HP:0001442 Typified by somatic mosaicism
HP:0006740 Transitional cell carcinoma of the bladder
HP:0000006 Autosomal dominant inheritance
HP:0006716 Hereditary nonpolyposis colorectal carcinoma
HP:0006753 Neoplasm of the stomach
HP:0002891 Uterine leiomyosarcoma
Displaying all 3 entries
Gene ID Gene Symbol Description
5320 PLA2G2A phospholipase A2 group IIA
4893 NRAS NRAS proto-oncogene, GTPase
5290 PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: March 31, 2025