steatotic liver disease

Summary
Synonym
  • Fatty change of liver
  • SLD
  • Steatosis of liver
  • alcoholic fatty liver
  • fatty liver disease
  • hepatic lipidosis
  • hepatic steatosis
Definition
A lipid storage disease characterized by the accumulation of large vacuoles of triglyceride fat in at least 5% of hepatocytes.
Super Class
lipid storage disease liver disease
Disease Ontology
DOID:9452
Mondo Disease Ontology
MeSH
UMLS
OMIM
MGI genotype (from TogoID)
WikiPathways (from TogoID)
Related Genes
Displaying entries 21 - 30 of 60 in total
Gene ID Gene Symbol Description Source
2876 GPX1 glutathione peroxidase 1
3030 HADHA hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha
3032 HADHB hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta
3077 HFE homeostatic iron regulator
3309 HSPA5 heat shock protein family A (Hsp70) member 5
3356 HTR2A 5-hydroxytryptamine receptor 2A
3357 HTR2B 5-hydroxytryptamine receptor 2B
3569 IL6 interleukin 6
3586 IL10 interleukin 10
3598 IL13RA2 interleukin 13 receptor subunit alpha 2
Displaying entries 41 - 46 of 46 in total
Gene ID Gene Symbol Description Source
107476 Acaca acetyl-Coenzyme A carboxylase alpha
116939 Pnpla3 patatin-like phospholipase domain containing 3
140740 Sec63 SEC63 homolog, protein translocation regulator
227231 Cps1 carbamoyl-phosphate synthetase 1
238055 Apob apolipoprotein B
269378 Ahcy S-adenosylhomocysteine hydrolase
Displaying entries 11 - 20 of 29 in total
Gene ID Gene Symbol Description Source
25669 Cpe carboxypeptidase E
25747 Ppara peroxisome proliferator activated receptor alpha
29527 Ptgs2 prostaglandin-endoperoxide synthase 2
29581 Htr2b 5-hydroxytryptamine receptor 2B
29595 Htr2a 5-hydroxytryptamine receptor 2A
54225 Apob apolipoprotein B
54315 Ucp2 uncoupling protein 2
79114 Fgfr1 Fibroblast growth factor receptor 1
83516 Ppargc1a PPARG coactivator 1 alpha
85431 Nox4 NADPH oxidase 4
Displaying all 8 entries
Gene ID Gene Symbol Description Source
35362 Mtp Microsomal triacylglycerol transfer protein
37028 ACOX1 acyl-CoA oxidase 1
39954 Oatp74D Organic anion transporting polypeptide 74D
41549 Octbeta2R Octopamine beta2 receptor
42160 htl heartless
42549 InR Insulin-like receptor
43191 Hex-t2 Hexokinase testis 2
117364 Hex-t1 Hexokinase testis 1
Displaying all 5 entries
Gene ID Gene Symbol Description Source
30262 ins preproinsulin
30705 fgfr1a fibroblast growth factor receptor 1a
286833 mc4r melanocortin 4 receptor
406207 mttp microsomal triglyceride transfer protein
565316 dgat2 diacylglycerol O-acyltransferase 2
Displaying all 6 entries
Gene ID Gene Symbol Description Source Organism
378695 ins.L insulin L homeolog Xenopus laevis (African clawed frog)
378696 ins.S insulin S homeolog Xenopus laevis (African clawed frog)
395003 dgat2 diacylglycerol O-acyltransferase 2 Xenopus tropicalis (tropical clawed frog)
397782 fgfr1.S fibroblast growth factor receptor 1 S homeolog Xenopus laevis (African clawed frog)
399444 fgfr1.L fibroblast growth factor receptor 1 L homeolog Xenopus laevis (African clawed frog)
548648 fgfr1 fibroblast growth factor receptor 1 Xenopus tropicalis (tropical clawed frog)
Displaying entries 1 - 10 of 17 in total
Gene ID Gene Symbol Description Source
171619 C53D5.5 Gamma-glutamyltranspeptidase 1
171782 abt-2 ABC transporter domain-containing protein
174116 gldi-2 EGF-like domain-containing protein
175410 daf-2 Insulin-like receptor subunit beta;Protein kinase domain-containing protein;receptor protein-tyrosine kinase
176852 dsc-4 Microsomal triglyceride transfer protein homolog
177940 egl-21 Carboxypeptidase E
179053 cpr-4 Cathepsin B-like cysteine proteinase 4
180033 cpr-3 Cathepsin B-like cysteine proteinase 3
180289 mrp-7 Multidrug resistance protein mrp-7
180364 T03D8.6 Gamma-glutamyltransferase;Gamma-glutamyltranspeptidase 1
Displaying entries 1 - 10 of 12 in total
Gene ID Gene Symbol Description Source
850317 GLK1 glucokinase
850614 HXK1 hexokinase 1
850645 BPT1 ATP-binding cassette bilirubin transporter BPT1
851006 ECM38 gamma-glutamyltransferase
852092 PHO8 alkaline phosphatase PHO8
852128 EMI2 putative glucokinase
852639 HXK2 hexokinase 2
852667 POX1 acyl-CoA oxidase
853418 KAR2 Hsp70 family ATPase KAR2
854419 DGA1 diacylglycerol O-acyltransferase

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Last updated: December 9, 2024