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Standards Ontologies Notations
obesity

Summary
Definition
An overnutrition that is characterized by excess body fat, traditionally defined as an elevated ratio of weight to height (specifically 30 kilograms per meter squared), has_material_basis_in a multifactorial etiology related to excess nutrition intake, decreased caloric utilization, and genetic susceptibility, and possibly medications and certain disorders of metabolism, endocrine function, and mental illness.
Super Class
overnutrition
External Links
Disease Ontology
DOID:9970
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
OMIM
MGI genotype (from TogoID)
WikiPathways (from TogoID)
Related Genes
Displaying entries 271 - 280 of 333 in total
Gene ID Gene Symbol Description Source
54577 UGT1A7 UDP glucuronosyltransferase family 1 member A7
54578 UGT1A6 UDP glucuronosyltransferase family 1 member A6
54579 UGT1A5 UDP glucuronosyltransferase family 1 member A5
54600 UGT1A9 UDP glucuronosyltransferase family 1 member A9
54657 UGT1A4 UDP glucuronosyltransferase family 1 member A4
54658 UGT1A1 UDP glucuronosyltransferase family 1 member A1
54659 UGT1A3 UDP glucuronosyltransferase family 1 member A3
55586 MIOX myo-inositol oxygenase
55600 ITLN1 intelectin 1
55624 POMGNT1 protein O-linked mannose N-acetylglucosaminyltransferase 1 (beta 1,2-)
Displaying entries 1 - 10 of 36 in total
Gene ID Gene Symbol Description Source
11450 Adipoq adiponectin, C1Q and collagen domain containing
11652 Akt2 thymoma viral proto-oncogene 2
11668 Aldh1a1 aldehyde dehydrogenase family 1, subfamily A1
11815 Apod apolipoprotein D
12015 Bad BCL2-associated agonist of cell death
12846 Comt catechol-O-methyltransferase
12894 Cpt1a carnitine palmitoyltransferase 1a, liver
14380 G6pd2 glucose-6-phosphate dehydrogenase 2
14381 G6pdx glucose-6-phosphate dehydrogenase X-linked
14433 Gapdh glyceraldehyde-3-phosphate dehydrogenase
Displaying entries 1 - 10 of 27 in total
Gene ID Gene Symbol Description Source
24267 Comt catechol-O-methyltransferase
24377 G6pd glucose-6-phosphate dehydrogenase
24383 Gapdh glyceraldehyde-3-phosphate dehydrogenase
24385 Gck glucokinase
24536 Lepr leptin receptor
24577 Myc MYC proto-oncogene, bHLH transcription factor
24835 Tnf tumor necrosis factor
25058 Hk1 hexokinase 1
25059 Hk2 hexokinase 2
25233 Akt2 AKT serine/threonine kinase 2
Displaying entry 11 - 11 of 11 in total
Gene ID Gene Symbol Description Source
117364 Hex-t1 Hexokinase testis 1
Displaying 1 entry
Gene ID Gene Symbol Description Source
317743 gapdh glyceraldehyde-3-phosphate dehydrogenase
Displaying all 4 entries
Gene ID Gene Symbol Description Source
174578 gpd-4 Glyceraldehyde-3-phosphate dehydrogenase 4
174603 gpd-1 Glyceraldehyde-3-phosphate dehydrogenase 1
178046 gspd-1 Glucose-6-phosphate 1-dehydrogenase
180601 gpd-3 Glyceraldehyde-3-phosphate dehydrogenase 3
Displaying entries 1 - 10 of 11 in total
Gene ID Gene Symbol Description Source
850317 GLK1 glucokinase
850614 HXK1 hexokinase 1
851974 YPR1 trifunctional aldehyde reductase/carbonyl reductase (NADPH)/glucose 1-dehydrogenase (NADP(+)) YPR1
852128 EMI2 putative glucokinase
852639 HXK2 hexokinase 2
853106 TDH3 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) TDH3
853395 TDH1 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) TDH1
853465 TDH2 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) TDH2
854287 GCY1 glycerol 2-dehydrogenase (NADP(+)) GCY1
855480 ZWF1 glucose-6-phosphate dehydrogenase
Related Glycoprotein
The Human Phenotype Ontology
Displaying all 5 entries
HPO ID HPO Term
HP:0000007 Autosomal recessive inheritance
HP:0001513 Obesity
HP:0000006 Autosomal dominant inheritance
HP:0010982 Polygenic inheritance
HP:0012340 Decreased resting energy expenditure
Displaying all 2 entries
Gene ID Gene Symbol Description
9672 SDC3 syndecan 3
5167 ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: August 19, 2024