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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
obesity
Summary
- Definition
- An overnutrition that is characterized by excess body fat, traditionally defined as an elevated ratio of weight to height (specifically 30 kilograms per meter squared), has_material_basis_in a multifactorial etiology related to excess nutrition intake, decreased caloric utilization, and genetic susceptibility, and possibly medications and certain disorders of metabolism, endocrine function, and mental illness.
- Super Class
- overnutrition
External Links
- Disease Ontology
- DOID:9970
- Mondo Disease Ontology
- MeSH
- UMLS
- NCI Thesaurus
- OMIM
- MGI genotype (from TogoID)
-
- 3766125
- 3821619
- 3821616
- 3817475
- 3799316
- 3784993
- 3784991
- 3773447
- 3772367
- 3822317
- 3766122
- 3721145
- 3715252
- 3694548
- 3689720
- 3664551
- 3664276
- 3655835
- 5515728
- 7545554
- 7545550
- 7545546
- 6273993
- 5828524
- 5766495
- 5763310
- 5763241
- 3655832
- 5447549
- 5300906
- 3850836
- 3847120
- 3840234
- 3832410
- 3822318
- 3033164
- 3511746
- 3055585
- 3055584
- 3053798
- 3041643
- 3036853
- 3036852
- 3033165
- 3511747
- 2681522
- 2680503
- 2669229
- 2663736
- 2654708
- 2653295
- 2651886
- 2388265
- 3589409
- 3655811
- 3639781
- 3639355
- 3639354
- 3629805
- 3623749
- 3620067
- 3611807
- 2174793
- 3586756
- 3582615
- 3580003
- 3579026
- 3577766
- 3526863
- 3511748
- WikiPathways (from TogoID)
Related Genes
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 1634 | DCN | decorin | |
| 1636 | ACE | angiotensin I converting enzyme | |
| 1645 | AKR1C1 | aldo-keto reductase family 1 member C1 | |
| 1646 | AKR1C2 | aldo-keto reductase family 1 member C2 | |
| 1892 | ECHS1 | enoyl-CoA hydratase, short chain 1 | |
| 2026 | ENO2 | enolase 2 | |
| 2180 | ACSL1 | acyl-CoA synthetase long chain family member 1 | |
| 2182 | ACSL4 | acyl-CoA synthetase long chain family member 4 | |
| 2194 | FASN | fatty acid synthase | |
| 2215 | FCGR3B | Fc gamma receptor IIIb |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 59027 | Nampt | nicotinamide phosphoribosyltransferase | |
| 68054 | Serpina12 | serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 12 | |
| 72774 | Neil1 | nei endonuclease VIII-like 1 (E. coli) | |
| 103988 | Gck | glucokinase | |
| 105787 | Prkaa1 | protein kinase, AMP-activated, alpha 1 catalytic subunit | |
| 230796 | Wdtc1 | WD and tetratricopeptide repeats 1 |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 24267 | Comt | catechol-O-methyltransferase | |
| 24377 | G6pd | glucose-6-phosphate dehydrogenase | |
| 24383 | Gapdh | glyceraldehyde-3-phosphate dehydrogenase | |
| 24385 | Gck | glucokinase | |
| 24536 | Lepr | leptin receptor | |
| 24577 | Myc | MYC proto-oncogene, bHLH transcription factor | |
| 24835 | Tnf | tumor necrosis factor | |
| 25058 | Hk1 | hexokinase 1 | |
| 25059 | Hk2 | hexokinase 2 | |
| 25233 | Akt2 | AKT serine/threonine kinase 2 |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 31293 | N | Notch | |
| 32545 | Gapdh2 | Glyceraldehyde 3 phosphate dehydrogenase 2 | |
| 32974 | Zw | Zwischenferment | |
| 35728 | Gapdh1 | Glyceraldehyde 3 phosphate dehydrogenase 1 | |
| 37028 | ACOX1 | acyl-CoA oxidase 1 | |
| 37447 | Sdc | Syndecan | |
| 39404 | INPP5E | Inositol polyphosphate 5-phosphatase E | |
| 43191 | Hex-t2 | Hexokinase testis 2 | |
| 43222 | Tl | Toll | |
| 44643 | Cnx99A | Calnexin 99A |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 850317 | GLK1 | glucokinase | |
| 850614 | HXK1 | hexokinase 1 | |
| 851974 | YPR1 | trifunctional aldehyde reductase/carbonyl reductase (NADPH)/glucose 1-dehydrogenase (NADP(+)) YPR1 | |
| 852128 | EMI2 | putative glucokinase | |
| 852639 | HXK2 | hexokinase 2 | |
| 853106 | TDH3 | glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) TDH3 | |
| 853395 | TDH1 | glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) TDH1 | |
| 853465 | TDH2 | glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) TDH2 | |
| 854287 | GCY1 | glycerol 2-dehydrogenase (NADP(+)) GCY1 | |
| 855480 | ZWF1 | glucose-6-phosphate dehydrogenase |
Related Glycoprotein
| UniProt ID | Protein Name | Source |
|---|---|---|
| P07741 | Adenine phosphoribosyltransferase | |
| P08571 | Monocyte differentiation antigen CD14 | |
| P08842 | Steryl-sulfatase | |
| P09104 | Gamma-enolase | |
| P09326 | CD48 antigen | |
| P09382 | Galectin-1 | |
| P09848 | Lactase/phlorizin hydrolase | |
| P09874 | Poly [ADP-ribose] polymerase 1 | |
| P10645 | Chromogranin-A | |
| P11150 | Hepatic triacylglycerol lipase |
- The Human Phenotype Ontology
| HPO ID | HPO Term |
|---|---|
| HP:0000007 | Autosomal recessive inheritance |
| HP:0001513 | Obesity |
| HP:0000006 | Autosomal dominant inheritance |
| HP:0010982 | Polygenic inheritance |
| HP:0012340 | Decreased resting energy expenditure |
