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butyrylcholinesterase

Summary

Gene Symbol

Bche

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

12038

PubChem

12038

Alliance of Genome Resources

MGI:894278

Annotation

Keyword

Disulfide bond
Glycoprotein
Phosphoprotein
Reference proteome
Secreted
Serine esterase
Signal

Proteins

Displaying 1 entry
UniProt	Protein Name
Q03311	Acylcholine acylhydrolase Butyrylcholine esterase Choline esterase II Pseudocholinesterase

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entry **11 - 11** of 11 in total

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GO Term	Evidence Code	PMID
neuroblast differentiation	IEA ISO

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

ammonium ion metabolic process [inference]

choline metabolic process

organonitrogen compound metabolic process [inference]

acetylcholine metabolic process [inference]

acetylcholine catabolic process

choline metabolic process

organonitrogen compound catabolic process [inference]

acetylcholine catabolic process

catabolic process [inference]

organic substance catabolic process [inference]

organonitrogen compound catabolic process [inference]

acetylcholine catabolic process

organic substance metabolic process [inference]

acetate ester metabolic process [inference]

acetylcholine metabolic process [inference]

acetylcholine catabolic process

organonitrogen compound metabolic process [inference]

acetylcholine metabolic process [inference]

acetylcholine catabolic process

choline metabolic process

organonitrogen compound catabolic process [inference]

acetylcholine catabolic process

organic substance catabolic process [inference]

organonitrogen compound catabolic process [inference]

acetylcholine catabolic process

cellular process [inference]

cellular developmental process [inference]

cell differentiation [inference]

neuroblast differentiation

multicellular organismal process [inference]

system process [inference]

nervous system process [inference]

cognition [inference]

learning or memory [inference]

learning

behavior [inference]

learning or memory [inference]

learning

developmental process [inference]

cellular developmental process [inference]

cell differentiation [inference]

neuroblast differentiation

response to stimulus [inference]

response to external stimulus [inference]

response to extracellular stimulus [inference]

response to nutrient levels [inference]

response to nutrient

response to vitamin [inference]

response to folic acid

response to endogenous stimulus [inference]

response to hormone [inference]

response to steroid hormone [inference]

response to corticosteroid [inference]

response to glucocorticoid

response to chemical [inference]

response to nutrient

response to vitamin [inference]

response to folic acid

response to xenobiotic stimulus

response to organic substance [inference]

response to hormone [inference]

response to steroid hormone [inference]

response to corticosteroid [inference]

response to glucocorticoid

response to organonitrogen compound [inference]

response to organic cyclic compound [inference]

response to steroid hormone [inference]

response to corticosteroid [inference]

response to glucocorticoid

response to folic acid

response to lipid [inference]

response to steroid hormone [inference]

response to corticosteroid [inference]

response to glucocorticoid

response to nitrogen compound [inference]

response to organonitrogen compound [inference]

response to oxygen-containing compound [inference]

response to folic acid

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

negative regulation of signaling [inference]

negative regulation of synaptic transmission

regulation of trans-synaptic signaling [inference]

modulation of chemical synaptic transmission [inference]

negative regulation of synaptic transmission

negative regulation of biological process [inference]

negative regulation of signaling [inference]

negative regulation of synaptic transmission

negative regulation of cellular process [inference]

negative regulation of cell population proliferation

negative regulation of cell communication [inference]

negative regulation of synaptic transmission

regulation of cellular process [inference]

regulation of cell communication [inference]

negative regulation of cell communication [inference]

negative regulation of synaptic transmission

regulation of trans-synaptic signaling [inference]

modulation of chemical synaptic transmission [inference]

negative regulation of synaptic transmission

regulation of cell population proliferation [inference]

negative regulation of cell population proliferation

negative regulation of cellular process [inference]

negative regulation of cell population proliferation

negative regulation of cell communication [inference]

negative regulation of synaptic transmission

Displaying **all 5** entries
GO Term	Evidence Code	PMID
endoplasmic reticulum lumen	IEA ISO
plasma membrane	IBA
nuclear envelope lumen	IDA	8651510
endoplasmic reticulum	IDA	8651510
extracellular space	IBA IEA ISO

GO Hierarchy

cellular component

cellular anatomical entity [inference]

extracellular space

membrane [inference]

plasma membrane

membrane-enclosed lumen [inference]

organelle lumen [inference]

intracellular organelle lumen [inference]

endoplasmic reticulum lumen

organelle envelope lumen [inference]

nuclear envelope lumen

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

Displaying **all 4** entries
GO Term	Evidence Code	PMID
choline binding	IEA ISO
cholinesterase activity	ISO ISS
identical protein binding	IEA ISO
acetylcholinesterase activity	IBA IDA	17212694

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on ester bonds [inference]

carboxylic ester hydrolase activity [inference]

cholinesterase activity

acetylcholinesterase activity

binding [inference]

protein binding [inference]

identical protein binding

ion binding [inference]

cation binding [inference]

choline binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Rodentia

Group Name

cholinesterase

Functional Category

E: Amino acid transport and metabolism
I: Lipid transport and metabolism
O: Posttranslational modification, protein turnover, chaperones

Displaying **all 5** entries
Gene Ontology
acetylcholine catabolic process
acetylcholinesterase activity
choline metabolic process
cholinesterase activity
hydrolase activity

Displaying **all 6** entries
InterPro
Acetylcholinesterase, tetramerisation domain
Alpha/Beta hydrolase fold
Carboxylesterase type B, active site
Carboxylesterase type B, conserved site
Carboxylesterase, type B
Cholinesterase

Disease

Disease Ontology

Displaying entry **21 - 21** of 21 in total

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DO ID	Disease Name	Source
DOID:9976	heroin dependence	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of **107** in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Homo sapiens	590		HGNC:983	HUMAN73262
Drosophila melanogaster	41625		FB:FBgn0000024
Rattus norvegicus	65036	10116_1:000ef6	RGD:619996	RATNO24582
Caenorhabditis elegans	171905		WB:WBGene00000036
Caenorhabditis elegans	175074		WB:WBGene00000038
Caenorhabditis elegans	175076		WB:WBGene00000037
Caenorhabditis elegans	181706		WB:WBGene00000035
Pan troglodytes	460830			PANTR32582
Canis lupus familiaris	488143			CANLF13616
Felis catus	493960			FELCA23175

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Last updated: December 9, 2024