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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
glucose-6-phosphate dehydrogenase
Summary
- Gene Symbol
-
- G6PD
- Aliases
-
- G6PD1
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Acetylation
- Alternative splicing
- Cytoplasm
- Direct protein sequencing
- Disease variant
- Glucose metabolism
- Hereditary hemolytic anemia
- Hydroxylation
- Membrane
- NADP
- Oxidoreductase
- Phosphoprotein
- Reference proteome
- Proteins
| UniProt | Protein Name |
|---|---|
| A0A384NL00 |
|
| P11413 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| negative regulation of protein glutathionylation | ||
| response to ethanol | ||
| negative regulation of reactive oxygen species metabolic process |
GO Hierarchy
biological process
metabolic process [inference]
nitrogen compound metabolic process [inference]
cellular metabolic process [inference]
primary metabolic process [inference]
small molecule metabolic process [inference]
organic substance metabolic process [inference]
cellular process [inference]
response to stimulus [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of metabolic process [inference]
regulation of localization [inference]
regulation of growth [inference]
positive regulation of biological process [inference]
negative regulation of biological process [inference]
regulation of developmental process [inference]
regulation of cellular process [inference]
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| glucose binding | ||
| protein homodimerization activity | ||
| glucose-6-phosphate dehydrogenase activity | ||
| protein binding | ||
| NADP binding |
GO Hierarchy
Human Protein Atlas
Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.
KEGG BRITE Database
Rhea
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:10763 | hypertension | |
| DOID:10783 | methemoglobinemia | |
| DOID:10825 | essential hypertension | |
| DOID:10844 | Japanese encephalitis | |
| DOID:10871 | age related macular degeneration | |
| DOID:10923 | sickle cell anemia | |
| DOID:10930 | borderline personality disorder | |
| DOID:10952 | nephritis | |
| DOID:1098 | fetal erythroblastosis | |
| DOID:1099 | alpha thalassemia |
- The Human Phenotype Ontology
| HPO ID | HPO Term |
|---|---|
| HP:0000952 | Jaundice |
| HP:0000980 | Pallor |
| HP:0001423 | X-linked dominant inheritance |
| HP:0001744 | Splenomegaly |
| HP:0001923 | Reticulocytosis |
| HP:0001945 | Fever |
| HP:0001974 | Leukocytosis |
| HP:0002027 | Abdominal pain |
| HP:0003577 | Congenital onset |
| HP:0003593 | Infantile onset |
| Disease ID | Disease Name |
|---|---|
| OMIM:300908 |
|
PubChem Disease
- GHR Health Conditions
- MedGen Diseases
- OMIM Phenotypes
- KEGG Diseases
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 178046 | WB:WBGene00007108 | ||
| 32974 | FB:FBgn0004057 | ||
| 102351638 | LATCH03379 | ||
| 570579 | ZFIN:ZDB-GENE-070508-4 | DANRE47177 | |
| 103035433 | ASTMX13735 | ||
| 108276043 | ICTPU07172 | ||
| 108276145 | ICTPU08049 | ||
| 113583111 | ELEEL31247 | ||
| 105026317 | ESOLU35273 | ||
| 115166188 | SALTR87855 |
