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G58896AZ

Summary

GlyTouCan ID: G58896AZ
IUPAC Condensed: Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-
Motifs: Paragloboside
Subsumption Level: Fully-defined saccharide
Monoisotopic Mass: 707.25

External Links

GlyGen

G58896AZ

ChEBI

61844

PubChem Compound

21670519

PubChem Substance

252288216

The Human Metabolome Database

HMDB0006567

CarbBank

163 459 460 461 462 2503 3051 4494 4495 4648 4853 4854 5301 5540 6248 8359 8572 8762 9295 11586 12614 14073 14079 14427 14486 14858 15259 15283 15550 16226 16357 16406 16463 16475 16870 16880 16894 17010 17107 17420 17493 17687 17703 18483 18919 19336 21118 21626 21627 21720 21732 21770 21919 22112 22489 22624 23026 23063 23877 23890 23902 23905 23937 23939 24439 24441 24769 25255 25275 25309 25361 25468 25517 25855 25878 26171 26269 26358 26601 26608 26617 27234 27472 27535 27536 27709 28497 28505 29758 30298 31662 31692 31752 32022 32741 32884 33047 33734 33883 35093 35365 35503 35924 35952 36002 36118 36168 37063 37094 37214 37266 37842 38059 38093 38371 39385 40564 41774 41777 41871 41905 41926 42846 42955 43214 43867 44621 45488 46804 47204 47563 47599 47660 47781 48137 48205 48549 49338 50187 50497 50735

3D Structures

GLYCAM: DGalpb1-4DGlcpNAcb1-3DGalpb1-4DGlcpb1-OH

GlycoShape

G58896AZ

Displaying 1 entry
Archetype	α	β
G00070MO	G14632ZD	G58896AZ

Organisms

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Organisms	Evidence
Oryctolagus cuniculus (rabbit)	GlyTouCan(glycome-db)
Ovis aries (sheep)	GlyTouCan(glycome-db)
Gallus gallus (chicken)	GlyTouCan(glycome-db)
Streptococcus pneumoniae	GlyTouCan(bcsdb)
Cricetinae (hamsters)	GlyTouCan(glycome-db)

Taxonomic Hierarchy

root

cellular organisms [inference]

Eukaryota (eucaryotes) [inference]

Opisthokonta [inference]

Metazoa (metazoans) [inference]

Eumetazoa [inference]

Bilateria [inference]

Deuterostomia [inference]

Chordata (chordates) [inference]

Craniata [inference]

Vertebrata (vertebrates) [inference]

Gnathostomata (jawed vertebrates) [inference]

Teleostomi [inference]

Euteleostomi (bony vertebrates) [inference]

Sarcopterygii [inference]

Dipnotetrapodomorpha [inference]

Tetrapoda (tetrapods) [inference]

Amniota (amniotes) [inference]

Mammalia (mammals) [inference]

Theria [inference]

Eutheria (placentals) [inference]

Boreoeutheria [inference]

Laurasiatheria [inference]

Carnivora (carnivores) [inference]

Caniformia [inference]

Canidae (dog, coyote, wolf, fox) [inference]

Canis [inference]

Canis lupus (gray wolf) [inference]

Canis lupus familiaris (dog)

Artiodactyla (even-toed ungulates & whales) [inference]

Ruminantia [inference]

Ovis aries (sheep)

Bovinae [inference]

Bos (cattle) [inference]

Bos taurus (domestic cattle)

Suina [inference]

Suidae (pigs) [inference]

Sus [inference]

Sus scrofa (pig)

Euarchontoglires [inference]

Glires (Rodents and rabbits) [inference]

Rodentia (rodent) [inference]

Myomorpha (mice and others) [inference]

Muroidea [inference]

Muridae [inference]

Murinae [inference]

Mus (mice) [inference]

Mus [inference]

Mus musculus (house mouse)

Rattus

Cricetidae [inference]

Cricetinae (hamsters)

Cricetulus [inference]

Cricetulus griseus (Chinese hamster)

Lagomorpha [inference]

Leporidae (rabbits and hares) [inference]

Oryctolagus [inference]

Oryctolagus cuniculus (rabbit)

Primates [inference]

Haplorrhini [inference]

Simiiformes [inference]

Catarrhini [inference]

Hominoidea (apes) [inference]

Hominidae (great apes) [inference]

Homininae [inference]

Homo [inference]

Homo sapiens (human)

Sauropsida (sauropsids) [inference]

Sauria (diapsids) [inference]

Archelosauria [inference]

Archosauria [inference]

Dinosauria [inference]

Saurischia [inference]

Theropoda [inference]

Coelurosauria [inference]

Aves (birds) [inference]

Neognathae [inference]

Galloanserae [inference]

Galliformes (landfowls) [inference]

Phasianidae (turkeys) [inference]

Phasianinae [inference]

Gallus [inference]

Gallus gallus (chicken)

Bacteria (eubacteria) [inference]

Pseudomonadota [inference]

Betaproteobacteria [inference]

Neisseriales [inference]

Neisseriaceae [inference]

Neisseria [inference]

Neisseria gonorrhoeae

Terrabacteria group [inference]

Bacillota [inference]

Bacilli [inference]

Lactobacillales [inference]

Streptococcaceae [inference]

Streptococcus [inference]

Streptococcus pneumoniae

GlycoGene Database (GGDB)

Displaying **all 4** entries
Gene Symbol	Donor	Acceptor	Reducing terminal(Acceptor)	Product	Reducing terminal(Product)	Reference
ST6GAL2	CMP-Neu5Ac	G58896AZ	Free	G83513YI	Free	12235148
B4GALT4	UDP-Gal	G06239NA	Cer	G58896AZ	Cer	9792633
B4GALT3	UDP-Gal	G06239NA	R	G58896AZ	R	9792633
B4GALT3	UDP-Gal	G06239NA	Cer	G58896AZ	Cer	9405390

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Gene Symbol	Donor	Acceptor	Reducing terminal(Acceptor)	Product	Reducing terminal(Product)	Reference
ST3GAL6	CMP-Neu5Ac	G58896AZ	ceramide	G01767JJ	ceramide	10206952
ST6GAL2	CMP-Neu5Ac	G58896AZ	Free	G83513YI	Free	12235148
B4GALT4	UDP-Gal	G06239NA	Cer	G58896AZ	Cer	9792633
B4GALT3	UDP-Gal	G06239NA	R	G58896AZ	R	9792633
B4GALT1	UDP-Gal	G06239NA	N-linked > O-linked	G58896AZ	N-linked > O-linked	10580128

Displaying entries **1 - 5** of 14 in total

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Gene Symbol	Donor	Acceptor	Reducing terminal(Acceptor)	Reference
ST6GALNAC6	CMP-Neu5Ac	G58896AZ	ceramide	12668675
ST3GAL1	CMP-Neu5Ac	G58896AZ	free	8288606
ST6GALNAC5	CMP-Neu5Ac	G58896AZ	ceramide	12668675
FUT7	GDP-Fuc	G58896AZ	Free	8182079
B3GALT1	UDP-Gal	G58896AZ	Cer	9582303

KEGG BRITE Database

KEGG ID

G00050

Enzyme

References

2960671

Reactions

Displaying **all 8** entries
KEGG Reaction	Enzyme	Acceptor	Product
R05975	2.4.1.149	G58896AZ	G70874WW
R06024	2.4.1.69	G58896AZ	G13636IT
R06026	2.4.3.6	G58896AZ	G01767JJ
R05978	2.4.1.87	G58896AZ	G60645OK
R11378	2.4.1.79	G58896AZ	G32252UW
R11375	2.4.1.228	G58896AZ	G12460DL
R06025	2.4.1.- 2.4.1.152 2.4.1.65	G58896AZ	G72002FC
R05977	2.4.1.- 2.4.1.275	G06239NA	G58896AZ

GlycoEpitope

Epitope ID: EP0075

Sequence Descriptors

GlycoCT

RES
1b:b-dglc-HEX-1:5
2b:b-dgal-HEX-1:5
3b:b-dglc-HEX-1:5
4s:n-acetyl
5b:b-dgal-HEX-1:5
LIN
1:1o(4+1)2d
2:2o(3+1)3d
3:3d(2+1)4n
4:3o(4+1)5d

WURCS

WURCS=2.0/3,4,3/[a2122h-1b_1-5][a2112h-1b_1-5][a2122h-1b_1-5_2*NCC/3=O]/1-2-3-2/a4-b1_b3-c1_c4-d1

Literature

Displaying entries **41 - 50** of 57 in total

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PubMed ID	Title	First Author	Publication Date	Source
8416736	Lactotetraose series ganglioside 3',6'-isoLD1 in tumors of central nervous and other systems in vitro and in vivo	Wikstrand CJ	1993 Jan 01	PubChem
1370278	Characterization of I/F1 glycoprotein as a receptor for Mycoplasma pneumoniae	Hengge UR	1992 Jan	PubChem
1910009	Eight lipooligosaccharides of Neisseria meningitidis react with a monoclonal antibody which binds lacto-N-neotetraose (Gal beta 1-4GlcNAc beta 1-3Gal beta 1-4Glc)	Tsai CM	1991 Oct	PubChem
2563403	Expression of lacto series type 2 antigens in human renal cell carcinoma and its clinical significance	Fukushi Y	1989 Mar 01	GlyGen GlycoEpitope
2474254	Immunohistochemical analysis of LNT, NeuAc2----3LNT, and Lex carbohydrate antigens in human tumors and normal tissues	Garin-Chesa P	1989 Jun	PubChem
2452383	Monoclonal IgM with unique specificity to gangliosides GM 1 and GD 1b and to lacto‐ N ‐tetraose associated with human motor neuron disease	Latov N	1988 May	PubChem
3345524	Detection of patients with cancer by monoclonal antibody directed to lactoneotetraosylceramide (paragloboside)	Myoga A	1988 Mar 15	GlyGen GlycoEpitope
3294333	Human sperm carbohydrate antigens defined by an antisperm human monoclonal antibody derived from an infertile woman bearing antisperm antibodies in her serum	Tsuji Y	1988 Jul 01	GlyGen GlycoEpitope
2823004	Differentiation antigens defined by mouse monoclonal antibodies against human germ cell tumors	Fujimoto J	1987 Oct	GlyGen GlycoEpitope
3112156	Oncofetal expression of Lex carbohydrate antigens in human colonic adenocarcinomas. Regulation through type 2 core chain synthesis rather than fucosylation	Holmes EH	1987 Aug 15	GlyGen GlycoEpitope

PubAnnotation

Displaying entries **1 - 5** of 10 in total

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Title	Authors	Source	Publication Date	PubMed ID
Molecular cloning and characterization of UDP-GlcNAc:lactosylceramide beta 1,3-N-acetylglucosaminyltransferase (beta 3Gn-T5), an essential enzyme for the expression of HNK-1 and Lewis X epitopes on glycolipids.	Togayachi A Akashima T Ookubo R Kudo T Nishihara S Iwasaki H Natsume A Mio H Inokuchi J Irimura T Sasaki K Narimatsu H	J Biol Chem	2001 Jun 22	11283017
Molecular cloning and characterization of a human beta-Gal-3'-sulfotransferase that acts on both type 1 and type 2 (Gal beta 1-3/1-4GlcNAc-R) oligosaccharides.	Honke K Tsuda M Koyota S Wada Y Iida-Tanaka N Ishizuka I Nakayama J Taniguchi N	J Biol Chem	2001 Jan 5	11029462
Cloning of a mouse beta 1,3 N-acetylglucosaminyltransferase GlcNAc(beta 1,3)Gal(beta 1,4)Glc-ceramide synthase gene encoding the key regulator of lacto-series glycolipid biosynthesis.	Henion TR Zhou D Wolfer DP Jungalwala FB Hennet T	J Biol Chem	2001 Aug 10	11384981
Cloning and expression of a novel galactoside beta1, 3-glucuronyltransferase involved in the biosynthesis of HNK-1 epitope.	Shimoda Y Tajima Y Nagase T Harii K Osumi N Sanai Y	J Biol Chem	1999 Jun 11	10358066
Molecular cloning of a novel alpha2,3-sialyltransferase (ST3Gal VI) that sialylates type II lactosamine structures on glycoproteins and glycolipids.	Okajima T Fukumoto S Miyazaki H Ishida H Kiso M Furukawa K Urano T Furukawa K	J Biol Chem	1999 Apr 23	10206952

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

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Guidelines

Summary

External Links

KEGG BRITE Database

GlycoEpitope

Sequence Descriptors

International Collaboration

Acknowledgements