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HLA class II histocompatibility antigen, DP beta 1 chain

Summary

UniProt ID

P04440

Gene Symbol

HLA-DPB1
HLA-DP1B

Organism

Homo sapiens (human)

External Links

GlyConnect

1366

GlyGen

P04440

RaftProt

P04440

Annotation

Keyword

3D-structure
Cell membrane
Disulfide bond
Endoplasmic reticulum
Endosome
Glycoprotein
Golgi apparatus
Lysosome
MHC II
Reference proteome
Signal
Transmembrane helix

Gene Ontology (GO)

Displaying **all 8** entries
GO Term
adaptive immune response
positive regulation of immune response
positive regulation of type II interferon production
positive regulation of T cell proliferation
positive regulation of T cell activation
antigen processing and presentation of exogenous peptide antigen via MHC class II
T cell receptor signaling pathway
peptide antigen assembly with MHC class II protein complex

Displaying entries **1 - 10** of 13 in total

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GO Term
Golgi membrane
lysosomal membrane
plasma membrane
membrane
MHC class II protein complex
transport vesicle membrane
endocytic vesicle membrane
clathrin-coated endocytic vesicle membrane
late endosome membrane
cell surface

Displaying **all 2** entries
GO Term
MHC class II protein complex binding
peptide antigen binding

Annotation information from UniProt.

Sequence

MMVLQVSAAPRTVALTALLMVLLTSVVQGRATPENYLFQGRQECYAFNGTQRFLERYIYNREEFARFDSDVGEFRAVTELGRPAAEYWNSQKDILEEKRAVPDRMCRHNYELGGPMTLQRRVQPRVNVSPSKKGPLQHHNLLVCHVTDFYPGSIQVRWFLNGQEETAGVVSTNLIRNGDWTFQILVMLEMTPQQGDVYTCQVEHTSLDSPVTVEWKAQSDSARSKTLTGAGGFVLGLIICGVGIFMHRRSKKVQRGSA

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying 1 entry
Position	Description	PubMed ID	GlyTouCan ID	Source
48	N-linked (GlcNAc...) asparagine		G32788FZ G05962QB G70232NH G35541EV G93718GY G80075MS G57776ZS G86880BF G80479JV G79666IR G45395BF G07246CJ G14972EH G43223CG G70441OD G76295SF G04657PL G27058EU G84452RH G51653BI G83460ZZ G41071NU G08290VR G80920RR G01485JJ G90659AW G62765YT G64527OM G11870QZ G47644PP G85269DF G05724UK G31852PQ G23719VF G11314AS G39188ZX G41247ZX G36379GD G94854LT G02815KT G92050GC G74724QE G92275SC G28681TP	UniProt GlyGen GlyConnect

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 7** entries
Pathway Name	Organism
Downstream TCR signaling	Homo sapiens
Generation of second messenger molecules	Homo sapiens
Interferon gamma signaling	Homo sapiens
MHC class II antigen presentation	Homo sapiens
PD-1 signaling	Homo sapiens
Phosphorylation of CD3 and TCR zeta chains	Homo sapiens
Translocation of ZAP-70 to Immunological synapse	Homo sapiens