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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Tyrosine-protein phosphatase non-receptor type 11
Summary
- UniProt ID
- Q06124
- Gene Symbol
-
- PTPN11
- PTP2C
- SHPTP2
- Organism
- Homo sapiens (human)
External Links
- GlyGen
- Q06124
- PubChem
- Q06124
- The Human Metabolome Database
- HMDBP08926
- RaftProt
- Q06124
Annotation
- Keyword
-
- 3D-structure
- Acetylation
- Alternative splicing
- Cytoplasm
- Deafness
- Disease variant
- Nucleus
- Phosphoprotein
- Protein phosphatase
- Reference proteome
- Repeat
- SH2 domain
- Gene Ontology (GO)
| GO Term |
|---|
| nucleoplasm |
| cytosol |
| nucleus |
| cytoplasm |
| protein-containing complex |
| GO Term |
|---|
| protein tyrosine kinase binding |
| phosphoprotein phosphatase activity |
| non-membrane spanning protein tyrosine phosphatase activity |
Sequence
MTSRRWFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNTGDYYDLYGGEKFATLAELVQYYMEHHGQLKEKNGDVIELKYPLNCADPTSERWFHGHLSGKEAEKLLTEKGKHGSFLVRESQSHPGDFVLSVRTGDDKGESNDGKSKVTHVMIRCQELKYDVGGGERFDSLTDLVEHYKKNPMVETLGTVLQLKQPLNTTRINAAEIESRVRELSKLAETTDKVKQGFWEEFETLQQQECKLLYSRKEGQRQENKNKNRYKNILPFDHTRVVLHDGDPNEPVSDYINANIIMPEFETKCNNSKPKKSYIATQGCLQNTVNDFWRMVFQENSRVIVMTTKEVERGKSKCVKYWPDEYALKEYGVMRVRNVKESAAHDYTLRELKLSKVGQGNTERTVWQYHFRTWPDHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDILIDIIREKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAVQHYIETLQRRIEEEQKSKRKGHEYTNIKYSLADQTSGDQSPLPPCTPTPPCAEMREDSARVYENVGLMQQQKSFR
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 566 |
|
|
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| FRS-mediated FGFR4 signaling | Homo sapiens |
| GAB1 signalosome | Homo sapiens |
| GPVI-mediated activation cascade | Homo sapiens |
| Interferon alpha/beta signaling | Homo sapiens |
| Interleukin-20 family signaling | Homo sapiens |
| Interleukin-3, Interleukin-5 and GM-CSF signaling | Homo sapiens |
| Interleukin-37 signaling | Homo sapiens |
| Interleukin-6 signaling | Homo sapiens |
| MAPK1 (ERK2) activation | Homo sapiens |
| MAPK3 (ERK1) activation | Homo sapiens |
Human Protein Atlas
Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.
