GlyCosmos Portal

Caenorhabditis elegans

Summary

Taxonomy ID: 6239
PubChem Taxonomy: 6239

Genes (1193) Glycans (3) Glycoproteins (1080) Lectins (37) Pathways (435)

Displaying entries **351 - 375** of **435** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol ▼
G alpha (i) signalling events	CELF35-1 Dopamine receptor 2 Dopamine receptor 3 G protein gamma domain-containing protein G-protein coupled receptors family 1 profile domain-containing protein G-protein coupled receptors family 1 profile domain-containing protein G-protein coupled receptors family 1 profile domain-containing protein G-protein coupled receptors family 1 profile domain-containing protein G-protein coupled receptors family 1 profile domain-containing protein G-protein coupled receptors family 1 profile domain-containing protein G-protein coupled receptors family 1 profile domain-containing protein G-protein coupled receptors family 1 profile domain-containing protein G-protein coupled receptors family 1 profile domain-containing protein G-protein coupled receptors family 1 profile domain-containing protein G-protein coupled receptors family 1 profile domain-containing protein G-protein coupled receptors family 1 profile domain-containing protein G-protein coupled receptors family 3 profile domain-containing protein G_PROTEIN_RECEP_F1_2 domain-containing protein G_PROTEIN_RECEP_F1_2 domain-containing protein Gamma-aminobutyric acid type B receptor subunit 1 Gamma-aminobutyric acid type B receptor subunit 2 Guanine nucleotide-binding protein alpha-16 subunit Guanine nucleotide-binding protein alpha-4 subunit Guanine nucleotide-binding protein alpha-6 subunit Guanine nucleotide-binding protein subunit beta-1 Guanine nucleotide-binding protein subunit beta-2 Guanine nucleotide-binding protein subunit gamma Muscarinic acetylcholine receptor gar-3 Neuropeptide receptor 18 Probable G-protein coupled receptor C06G4.5 Probable metabotropic glutamate receptor mgl-1 RGS domain-containing protein RGS domain-containing protein Regulator of G-protein signaling 7 Regulator of G-protein signaling egl-10 Regulator of G-protein signaling rgs-10 Regulator of G-protein signaling rgs-11 Regulator of G-protein signaling rgs-1 Regulator of G-protein signaling rgs-2 Regulator of G-protein signaling rgs-3 Regulator of G-protein signaling rgs-6 Regulator of G-protein signaling rgs-7 Regulator of G-protein signaling rgs-9 SERPIN domain-containing protein SERPIN domain-containing protein Serine or cysteine protease inhibitor Serine or cysteine protease inhibitor Serine or cysteine protease inhibitor Serpin domain-containing protein Serpin domain-containing protein Serpin domain-containing protein Serpin domain-containing protein Tetratricopeptide repeat protein 28 Tyramine receptor Ser-2 Tyramine receptor tyra-2 Tyrosine protein-kinase src-1	A0A0K3AXD3 A0A3B1DQQ4 A0A5S9MNH1 A1IMB8 A9Z1L1 E7EM37 G5ECB2 G5ECK9 G5ECT6 G5ECY2 G5ECZ3 G5EE40 G5EE56 G5EFH4 G5EGH0 H2KZ99 H2L0Q3 O01818 O02213 O17365 O17589 O18014 O45520 O45523 O45524 P17343 P34295 P34311 P49808 P49809 P54406 Q09502 Q09630 Q18287 Q18312 Q18563 Q19084 Q19651 Q19779 Q19955 Q1ZXT2 Q20636 Q20827 Q20841 Q23033 Q23376 Q6RYS9 Q7JP61 Q8MPR3 Q8WQC0 Q93743 Q9BIG5 Q9N2V6 Q9N452 Q9U7D5 Q9XVQ1	C06G4.5 C28G1.2 CELE_F15D3.4 CELE_F35H10.10 CELE_F44G3.7 CELE_F55D10.4 CELE_F57C9.6 CELE_ZK813.5 ador-1 ags-3 dop-2 dop-2L dop-3 eat-11 eat-16 egl-10 gar-3 gbb-1 gbb-2 gbp-2 gnrr-4 gpa-16 gpa-4 gpa-6 gpb-1 gpb-2 gpc-1 gpc-2 gtr-1 mgl-1 mgl-3 npr-16 npr-18 npr-23 npr-24 npr-25 npr-26 npr-28 octr-1 rgs-1 rgs-10 rgs-11 rgs-2 rgs-3 rgs-4 rgs-6 rgs-7 rgs-8.1 rgs-8.2 rgs-9 ser-2 ser-4 spn-1 src-1 srp-1 srp-2 srp-3 srp-6 srp-7 srp-8 tyra-2
Aflatoxin activation and detoxification	3-ketosteroid oxygenase CYtochrome P450 family CYtochrome P450 family CYtochrome P450 family CYtochrome P450 family CYtochrome P450 family CYtochrome P450 family CYtochrome P450 family CYtochrome P450 family CYtochrome P450 family CYtochrome P450 family CYtochrome P450 family CYtochrome P450 family CYtochrome P450 family CYtochrome P450 family CYtochrome P450 family CYtochrome P450 family CYtochrome P450 family CYtochrome P450 family CYtochrome P450 family CYtochrome P450 family CYtochrome P450 family CYtochrome P450 family CYtochrome P450 family CYtochrome P450 family CYtochrome P450 family CYtochrome P450 family CYtochrome P450 family CYtochrome P450 family CYtochrome P450 family CYtochrome P450 family CYtochrome P450 family CYtochrome P450 family CYtochrome P450 family CYtochrome P450 family CYtochrome P450 family CYtochrome P450 family CYtochrome P450 family Gamma-glutamyltransferase Gamma-glutamyltranspeptidase 1 Gamma-glutamyltranspeptidase 1 Gamma-glutamyltranspeptidase 1 Gamma-glutamyltranspeptidase 1 Gamma-glutamyltranspeptidase 1 N-acyl-aliphatic-L-amino acid amidohydrolase Probable cytochrome P450 CYP36A1 Probable cytochrome P450 cyp-35D1	A0A0M7RF98 A0A486WVP7 B5BM47 G5ECD0 G5EE22 H2KY69 H2KYS3 H2L030 H2L0B7 O02627 O02628 O02641 O16220 O16362 O16482 O16670 O16671 O16673 O18256 O44649 O44650 O44651 O44652 O44655 O44656 O44657 O44658 O44704 O44706 O45364 O45659 O61204 O61935 O62377 O62378 P90771 Q20315 Q27465 Q27470 Q27471 Q27482 Q27499 Q5WRS4 Q965T7 Q9N4Q4 Q9N5I1 Q9N5V4	C06A6.4 C53D5.5 CELE_H14N18.4 CELE_T03D8.6 CELE_T19H12.6 CELE_Y7A9A.1 CELE_Y97E10AR.2 cyp-23A1 cyp-23a1 cyp-33A1 cyp-33B1 cyp-33C1 cyp-33C11 cyp-33C12 cyp-33C2 cyp-33C3 cyp-33C4 cyp-33C5 cyp-33C6 cyp-33C7 cyp-33C8 cyp-33C9 cyp-33D1 cyp-33D3 cyp-33E1 cyp-33E2 cyp-33E3 cyp-33a1 cyp-33b1 cyp-33c1 cyp-33c11 cyp-33c12 cyp-33c2 cyp-33c3 cyp-33c4 cyp-33c5 cyp-33c6 cyp-33c7 cyp-33c8 cyp-33c9 cyp-33d1 cyp-33d3 cyp-33e1 cyp-33e2 cyp-33e3 cyp-34A1 cyp-34A10 cyp-34A2 cyp-34A5 cyp-34A6 cyp-34A7 cyp-34A8 cyp-34A9 cyp-34a1 cyp-34a10 cyp-34a2 cyp-34a4 cyp-34a5 cyp-34a6 cyp-34a7 cyp-34a8 cyp-34a9 cyp-35A1 cyp-35A2 cyp-35A3 cyp-35A4 cyp-35A5 cyp-35B1 cyp-35B2 cyp-35B3 cyp-35C1 cyp-35a1 cyp-35a2 cyp-35a3 cyp-35a4 cyp-35a5 cyp-35b1 cyp-35b2 cyp-35b3 cyp-35c1 cyp-35d1 cyp-36A1 cyp36a1 dach-1 daf-9
APAP ADME	3-ketosteroid oxygenase ABC transmembrane type-1 domain-containing protein ABC transporter domain-containing protein ABC transporter family G domain-containing protein CYtochrome P450 family CYtochrome P450 family CYtochrome P450 family CYtochrome P450 family CYtochrome P450 family CYtochrome P450 family CYtochrome P450 family CYtochrome P450 family CYtochrome P450 family CYtochrome P450 family CYtochrome P450 family CYtochrome P450 family CYtochrome P450 family CYtochrome P450 family CYtochrome P450 family CYtochrome P450 family CYtochrome P450 family CYtochrome P450 family CYtochrome P450 family CYtochrome P450 family CYtochrome P450 family CYtochrome P450 family CYtochrome P450 family CYtochrome P450 family CYtochrome P450 family CYtochrome P450 family CYtochrome P450 family CYtochrome P450 family CYtochrome P450 family CYtochrome P450 family CYtochrome P450 family CYtochrome P450 family CYtochrome P450 family CYtochrome P450 family CYtochrome P450 family CYtochrome P450 family CYtochrome P450 family Gamma-glutamyltransferase Gamma-glutamyltranspeptidase 1 Gamma-glutamyltranspeptidase 1 Gamma-glutamyltranspeptidase 1 Gamma-glutamyltranspeptidase 1 Gamma-glutamyltranspeptidase 1 Glucuronosyltransferase Glutathione S-transferase P Multidrug resistance protein mrp-7 Multidrug resistance-associated protein 1 Multidrug resistance-associated protein 1 Multidrug resistance-associated protein 1 Multidrug resistance-associated protein 1 Multidrug resistance-associated protein 5 Multidrug resistance-associated protein lethal(2)03659 N-acyl-aliphatic-L-amino acid amidohydrolase Peptidase M20 dimerisation domain-containing protein Probable cytochrome P450 CYP36A1 Probable cytochrome P450 cyp-35D1	A0A0M7RF98 A0A486WVP7 B5BM47 D7SFK1 G5ECD0 G5EE22 G5EE72 G5EFP3 H2KY69 H2KYS3 H2L030 H2L0B7 O02627 O02628 O02641 O16220 O16362 O16482 O16670 O16671 O16673 O18000 O18256 O44649 O44650 O44651 O44652 O44655 O44656 O44657 O44658 O44704 O44706 O45364 O45659 O61204 O61935 O62377 O62378 P10299 P90771 Q19048 Q19082 Q19585 Q19625 Q20315 Q20943 Q27465 Q27470 Q27471 Q27482 Q27499 Q3S1M2 Q5WRS4 Q965T7 Q9N4Q4 Q9N5I1 Q9N5V4 Q9U2G5 Q9XW61	C06A6.4 C53D5.5 CELE_H14N18.4 CELE_T03D8.6 CELE_T19H12.6 CELE_Y7A9A.1 CELE_Y97E10AR.2 abcx-1 cyp-23A1 cyp-23a1 cyp-33A1 cyp-33B1 cyp-33C1 cyp-33C11 cyp-33C12 cyp-33C2 cyp-33C3 cyp-33C4 cyp-33C5 cyp-33C6 cyp-33C7 cyp-33C8 cyp-33C9 cyp-33D1 cyp-33D3 cyp-33E1 cyp-33E2 cyp-33E3 cyp-33a1 cyp-33b1 cyp-33c1 cyp-33c11 cyp-33c12 cyp-33c2 cyp-33c3 cyp-33c4 cyp-33c5 cyp-33c6 cyp-33c7 cyp-33c8 cyp-33c9 cyp-33d1 cyp-33d3 cyp-33e1 cyp-33e2 cyp-33e3 cyp-34A1 cyp-34A10 cyp-34A2 cyp-34A5 cyp-34A6 cyp-34A7 cyp-34A8 cyp-34A9 cyp-34a1 cyp-34a10 cyp-34a2 cyp-34a4 cyp-34a5 cyp-34a6 cyp-34a7 cyp-34a8 cyp-34a9 cyp-35A1 cyp-35A2 cyp-35A3 cyp-35A4 cyp-35A5 cyp-35B1 cyp-35B2 cyp-35B3 cyp-35C1 cyp-35a1 cyp-35a2 cyp-35a3 cyp-35a4 cyp-35a5 cyp-35b1 cyp-35b2 cyp-35b3 cyp-35c1 cyp-35d1 cyp-36A1 cyp36a1 dach-1 daf-9 gst-1 mrp-1 mrp-2 mrp-3 mrp-4 mrp-5 mrp-6 mrp-7 mrp-8 pes-9 ugt-57 wht-5
Localization of the PINCH-ILK-PARVIN complex to focal adhesions	Integrin-linked protein kinase homolog pat-4 Uncharacterized integrin beta-like protein C05D9.3	Q9GYK2 Q9TZC4	C05D9.3 pat-4
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell	Integrin alpha pat-2 Uncharacterized integrin beta-like protein C05D9.3	P34446 Q9GYK2	C05D9.3 pat-2
Syndecan interactions	BMP-like protein unc-129 Dauer larva development regulatory growth factor daf-7 Integrin alpha ina-1 Integrin alpha pat-2 Integrin beta pat-3 Probable syndecan Protein dbl-1 Protein kinase C-like 2 Protein let-756 Uncharacterized integrin beta-like protein C05D9.3	G5EBY8 G5EEL5 P34446 P50605 P90980 P92172 Q03600 Q11184 Q27874 Q9GYK2	C05D9.3 cet-1 daf-7 dbl-1 ina-1 kin-11 let-756 pat-2 pat-3 pkc-2 sdn-1 unc-129
Molecules associated with elastic fibres	BMP-like protein unc-129 Dauer larva development regulatory growth factor daf-7 Fibulin-1 Integrin alpha pat-2 Integrin beta pat-3 Nidogen Protein dbl-1 Uncharacterized integrin beta-like protein C05D9.3	G5EBY8 G5EEL5 O77469 P34446 P92172 Q27874 Q93791 Q9GYK2	C05D9.3 cet-1 daf-7 dbl-1 fbl-1 fbln1 nid-1 pat-2 pat-3 unc-129
Signal transduction by L1	Casein kinase II subunit alpha Casein kinase II subunit beta Dual specificity mitogen-activated protein kinase kinase mek-2 Ig-like domain-containing protein Integrin alpha pat-2 Integrin beta pat-3 Mitogen-activated protein kinase mpk-1 Myoblast growth factor receptor egl-15 Protein vav-1 Ras-related protein ced-10 Receptor tyrosine-protein kinase let-23 Serine/threonine-protein kinase pak-1 Uncharacterized integrin beta-like protein C05D9.3	P18334 P24348 P28548 P34446 P39745 Q03206 Q10656 Q10664 Q17850 Q27874 Q45FX5 Q5WRR1 Q9GYK2	C05D9.3 ced-10 egl-15 kin-10 kin-3 kin-5 kin-7 let-23 mek-2 mpk-1 pak-1 pat-2 pat-3 rac-1 sur-1 vav-1 wrk-1
TGF-beta receptor signaling activates SMADs	BMP-like protein unc-129 Cell surface receptor daf-1 Cell surface receptor daf-4 Dauer larva development regulatory growth factor daf-7 Dwarfin sma-4 E3 ubiquitin-protein ligase CBL FYVE-type domain-containing protein Furin-like protease kpc-1 Integrin alpha pat-2 Integrin beta pat-3 Nidogen Protein dbl-1 Smad protein daf-8 Uncharacterized integrin beta-like protein C05D9.3 peptidylprolyl isomerase peptidylprolyl isomerase	G5EBY8 G5EEL5 H2KZI9 O17798 P20792 P34446 P45897 P50488 P92172 Q19019 Q21733 Q27874 Q8I4E5 Q93791 Q9GYK2 Q9U2Q8	C05D9.3 aka-1 cem-3 cet-1 daf-1 daf-4 daf-7 daf-8 dbl-1 fkb-2 fkb-8 kpc-1 nid-1 pat-2 pat-3 sli-1 sma-4 unc-129
Laminin interactions	Ig-like domain-containing protein Integrin alpha ina-1 Integrin beta pat-3 Multiple epidermal growth factor-like domains protein 6 Titin homolog Uncharacterized integrin beta-like protein C05D9.3	C6KRM7 G4SLH0 G5EFX3 Q03600 Q27874 Q9GYK2	C05D9.3 CELE_Y64G10A.7 ina-1 pat-3 rig-5 ttn-1
Turbulent (oscillatory, disturbed) flow shear stress activates signaling by PIEZO1 and integrins in endothelial cells	Inactive tyrosine-protein kinase kin-32 Integrin alpha pat-2 Integrin beta pat-3 Probable 3',5'-cyclic-AMP phosphodiesterase pde-4 Probable serine/threonine-protein phosphatase PP2A regulatory subunit Protein kinase domain-containing protein Serine/threonine-protein phosphatase 2A catalytic subunit Serine/threonine-protein phosphatase 2A regulatory subunit sur-6 Signal transducer and activator of transcription 1 Signal transducer and activator of transcription b Tyrosine-protein kinase abl-1 Uncharacterized integrin beta-like protein C05D9.3 Yes-associated protein homolog 1	D3YT30 G5EDR3 G5EGK8 P03949 P34446 Q09543 Q19404 Q20977 Q22000 Q27874 Q95YD4 Q9GYK2 Q9NAD6	C05D9.3 CELE_T12G3.2 abl-1 kin-32 let-92 paa-1 pat-2 pat-3 pde-4 sta-1 sta-2 stat-b sur-6 yap-1
RHOG GTPase cycle	10 kDa heat shock protein, mitochondrial CED-5 CRAL-TRIO domain-containing protein Cadherin-4 Calponin-homology (CH) domain-containing protein Caveolin-1 Caveolin-2 Cell death abnormality protein 12 Cell division control protein 42 homolog Cytoplasmic FMR1-interacting protein homolog DH domain-containing protein Ephrin receptor 1 Glutamate carboxypeptidase 2 homolog Intersectin-1 MAGUK family N-acetylated-alpha-linked acidic dipeptidase 2 NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial Phosphoinositide 3-kinase adapter subunit Phospholipase Probable rho GDP-dissociation inhibitor Protein kinase domain-containing protein Protein let-99 Protein vav-1 Protein vav Ras-related protein Rab-18 Ras-related protein Rab-7a Ras-related protein ced-10 Ras-related protein rac-2 Rho GTPase-activating protein 26 Rho GTPase-activating protein 68F Rho-GAP domain-containing protein SH2 domain-containing protein Serine/threonine-protein kinase max-2 Serine/threonine-protein kinase pak-1 Serine/threonine-protein kinase pak-2 Synaptobrevin-1 Target of ERK kinase mpk-1 Uncharacterized integrin beta-like protein C05D9.3 Uncharacterized protein F07F6.4 Vang-like protein WAPL domain-containing protein	A0A0K3AS36 G5EDP9 G5EDU3 G5EEN3 G5EF62 G5EFU0 G5EGQ3 H2KY90 H2KYI7 H2KZH5 H2KZV6 O02495 O17772 O44518 O45611 O61460 O61528 P91406 Q03206 Q05062 Q09531 Q17850 Q18879 Q19319 Q20496 Q21341 Q23130 Q23146 Q45FX5 Q7JP75 Q86NC2 Q8STE5 Q93332 Q94051 Q94124 Q95XW5 Q965J0 Q965Q1 Q9BL44 Q9GYK2 Q9NAC7	C05D9.3 CELE_T04C9.1 CELE_Y22D7AL.10 CELE_Y53F4B.1 CELE_Y71H2AM.12 F07F6.4 PLD aap-1 cav-1 cav-2 cdc-42 cdh-4 ced-10 ced-12 ced-5 cgef-1 cyk-1 ephx-1 gcp-2.1 gcp-2.2 gex-2 itsn-1 let-99 magu-1 max-2 nuo-2 pak-1 pak-2 pes-7 pld-1 rab-7 rac-1 rac-2 rga-1 rga-5 rhi-1 snb-1 toe-2 uig-1 unc-73 vab-1 vang-1 vav-1
Basigin interactions	Caveolin-1 Caveolin-2 Contactin rig-6 Ig-like domain-containing protein Integrin alpha ina-1 MFS domain-containing protein MFS domain-containing protein MMP-like protein Major facilitator superfamily (MFS) profile domain-containing protein Major facilitator superfamily (MFS) profile domain-containing protein Major facilitator superfamily (MFS) profile domain-containing protein Major facilitator superfamily (MFS) profile domain-containing protein Matrix metalloproteinase-A Matrix metalloproteinase-B Matrix metalloproteinase-C Peptidase metallopeptidase domain-containing protein Peptidyl-prolyl cis-trans isomerase 4 Peptidyl-prolyl cis-trans isomerase Probable sodium/potassium-transporting ATPase subunit beta-3 Sodium/potassium-transporting ATPase subunit beta-1 Sodium/potassium-transporting ATPase subunit beta Uncharacterized integrin beta-like protein C05D9.3 Uncharacterized protein	G5EBU3 G5ECC4 G5ECR3 G5EGM1 H2KZ60 H2L0E6 O17328 O17913 O44836 P52012 Q03600 Q18879 Q21182 Q22109 Q2L6V8 Q5WRR1 Q93235 Q93896 Q94051 Q9GYK2 Q9UAT3 Q9XUG9 Q9XUY5	C05D9.3 CELE_K03B8.6 CELE_T22F3.12 cav-1 cav-2 cyn-4 cyp-4 ina-1 mct-1 mct-2 mct-3 mct-4 mct-5 mct-6 mog-6 nkb-1 nkb-2 nkb-3 rig-6 slcf-1 wrk-1 zmp-1 zmp-2 zmp-3 zmp-5 zmp-6
RAC2 GTPase cycle	Arf-GAP domain-containing protein Armadillo repeat-containing domain-containing protein CED-5 CRAL-TRIO domain-containing protein Cadherin-4 Calponin-homology (CH) domain-containing protein Caveolin-1 Caveolin-2 Cell division control protein 42 homolog Cytoplasmic FMR1-interacting protein homolog DH domain-containing protein DH domain-containing protein Ephrin receptor 1 Glutamate carboxypeptidase 2 homolog MAGUK family Membrane-associated protein gex-3 Metaxin-1 homolog N-acetylated-alpha-linked acidic dipeptidase 2 PH domain-containing protein Phosphatidylinositol 3-kinase age-1 Phosphoinositide 3-kinase adapter subunit Phospholipase Probable rho GDP-dissociation inhibitor Protein BRICK1 Protein let-99 Protein vav-1 Rac GTPase-activating protein 1 Ras-related protein Rab-18 Ras-related protein Rab-7a Ras-related protein ced-10 Ras-related protein rac-2 Rho GTPase-activating protein 26 Rho GTPase-activating protein 68F Rho GTPase-activating protein syd-1 Rho-GAP domain-containing protein Rho-GAP domain-containing protein SAM50-like protein gop-3 SH3 domain-containing protein Serine/threonine-protein kinase SULU Serine/threonine-protein kinase max-2 Serine/threonine-protein kinase pak-1 Serine/threonine-protein kinase pak-2 Synaptobrevin-1 Target of ERK kinase mpk-1 Uncharacterized integrin beta-like protein C05D9.3 Vang-like protein WAPL domain-containing protein Wiskott-Aldrich syndrome protein family member	A0A0K3AR51 A0A2K5AU23 A5Z2X2 G5EDP9 G5EDU3 G5EEN3 G5EFU0 G5EGQ3 H2KY90 H2KYI7 H2KZH5 H2KZV6 O01847 O02495 O17772 O44518 O45503 O45611 O61460 O61528 P46549 P46576 P55163 P91406 Q03206 Q05062 Q10929 Q17850 Q18879 Q19319 Q19467 Q20496 Q21341 Q23130 Q23146 Q45FX5 Q7JP75 Q86NH1 Q93332 Q94051 Q94124 Q94125 Q95XW5 Q9BL44 Q9GYK2 Q9U1V2 Q9XUS9 Q9XVK6	C05D9.3 CELE_F22G12.5 CELE_T04C9.1 CELE_Y57G11C.1147 CELE_Y67A10A.7 CELE_Y71H2AM.12 PLD aap-1 abi-1 age-1 cav-1 cav-2 cdc-42 cdh-4 ced-10 ced-5 cgef-1 cyk-1 cyk-4 gcp-2.1 gcp-2.2 gex-2 gex-3 git-1 gop-3 kin-18 let-99 magu-1 max-2 mtx-1 pak-1 pak-2 pes-7 pld-1 rab-7 rac-1 rac-2 rga-1 rga-5 rga-8 rhi-1 snb-1 sulu syd-1 tiam-1 toe-2 unc-73 vab-1 vang-1 vav-1 wve-1
RAC3 GTPase cycle	Amino acid transporter Amino acid transporter Arf-GAP domain-containing protein CRAL-TRIO domain-containing protein Cadherin-4 Caveolin-1 Caveolin-2 Cell division control protein 42 homolog Cytoplasmic FMR1-interacting protein homolog DH domain-containing protein DH domain-containing protein Ephrin receptor 1 Excitatory amino acid transporter GTPase-activating protein pac-1 Glutamate carboxypeptidase 2 homolog MAGUK family Membrane-associated protein gex-3 N-acetylated-alpha-linked acidic dipeptidase 2 PH domain-containing protein Phosphoinositide 3-kinase adapter subunit Probable rho GDP-dissociation inhibitor Protein BRICK1 Protein let-99 Protein unc-112 Protein vav-1 Putative sodium-dependent excitatory amino acid transporter glt-3 Putative sodium-dependent excitatory amino acid transporter glt-4 Putative sodium-dependent excitatory amino acid transporter glt-6 Rac GTPase-activating protein 1 Rap guanine nucleotide exchange factor 1 Ras-related protein Rab-7a Ras-related protein ced-10 Rho GTPase-activating protein 26 Rho GTPase-activating protein 68F Rho GTPase-activating protein syd-1 Rho-GAP domain-containing protein Rho-GAP domain-containing protein Rho-GAP domain-containing protein Rho-GAP domain-containing protein Rho-GAP domain-containing protein Rho-GAP domain-containing protein SH3 domain-containing protein Serine/threonine-protein kinase SULU Serine/threonine-protein kinase max-2 Serine/threonine-protein kinase pak-1 Serine/threonine-protein kinase pak-2 Synaptobrevin-1 Synaptosomal-associated protein Target of ERK kinase mpk-1 Tyrosine-protein kinase abl-1 Uncharacterized integrin beta-like protein C05D9.3 Vang-like protein WAPL domain-containing protein WW domain-containing protein tag-325 Wiskott-Aldrich syndrome protein family member t-SNARE protein aex-4	A0A0K3AR51 A0A2K5AU23 A5PEW5 A5Z2X2 G5EDP9 G5EEN8 G5EFU0 G5EGQ3 H2KY90 H2KYI7 H2KZH5 H2KZV4 H2KZV6 H2KZX7 O01443 O01847 O02495 O17590 O18210 O44518 O45611 O61460 O61528 P03949 P34288 P46549 P46941 P55163 P91406 Q03206 Q05062 Q10901 Q10929 Q17850 Q18685 Q18879 Q19319 Q19370 Q19467 Q20496 Q21341 Q21353 Q21751 Q22682 Q23130 Q23146 Q45FX5 Q7JP75 Q86NH1 Q93332 Q94051 Q95XW5 Q9GYK2 Q9UAY8 Q9XUS9 Q9XVK6	C05D9.3 CELE_F22G12.5 CELE_F23H11.4 CELE_T04C9.1 CELE_Y34B4A.4 CELE_Y57G11C.1147 aap-1 abi-1 abl-1 aex-4 cav-1 cav-2 cdc-42 cdh-4 ced-10 cgef-1 cyk-1 cyk-4 gap gcp-2.1 gcp-2.2 gex-2 gex-3 git-1 glt-1 glt-3 glt-4 glt-5 glt-6 glt-7 kin-18 let-99 magu-1 max-2 ocrl-1 pac-1 pak-1 pak-2 rab-7 rac-1 rga-1 rga-5 rga-6 rga-8 rhi-1 ric-4 snb-1 srgp-1 sulu syd-1 tag-325 tag-81 tiam-1 toe-2 unc-112 unc-73 vab-1 vang-1 vav-1 wve-1
RAC1 GTPase cycle	Amino acid transporter Amino acid transporter Arf-GAP domain-containing protein C2 DOCK-type domain-containing protein CED-5 CRAL-TRIO domain-containing protein Calponin-homology (CH) domain-containing protein Caveolin-1 Caveolin-2 Cell division control protein 42 homolog Chimerin 2 Cytoplasmic FMR1-interacting protein homolog DH domain-containing protein DH domain-containing protein DH domain-containing protein Ephrin receptor 1 Excitatory amino acid transporter F-BAR domain-containing protein FYVE, RhoGEF and PH domain-containing protein tag-77 Formin-homology and zinc finger domains protein 1 GTPase-activating protein pac-1 Glutamate carboxypeptidase 2 homolog Guanine nucleotide exchange factor Guanine nucleotide-binding protein alpha-12 subunit MAGUK family Membrane-associated protein gex-3 Moesin/ezrin/radixin homolog 1 N-acetylated-alpha-linked acidic dipeptidase 2 PH domain-containing protein Partitioning defective protein 6 Phosphatidylinositol 3-kinase age-1 Phosphoinositide 3-kinase adapter subunit Phospholipase Probable rho GDP-dissociation inhibitor Protein BRICK1 Protein ECT2 Protein let-99 Protein unc-112 Protein vav-1 Protein vav Putative sodium-dependent excitatory amino acid transporter glt-3 Putative sodium-dependent excitatory amino acid transporter glt-4 Putative sodium-dependent excitatory amino acid transporter glt-6 Rac GTPase-activating protein 1 Ras-related protein Rab-7a Ras-related protein ced-10 Rho GTPase-activating protein 20 Rho GTPase-activating protein 26 Rho GTPase-activating protein 68F Rho GTPase-activating protein syd-1 Rho-GAP domain-containing protein Rho-GAP domain-containing protein Rho-GAP domain-containing protein Rho-GAP domain-containing protein Rho-GAP domain-containing protein Rho-GAP domain-containing protein SH2 domain-containing protein SH3 domain-containing protein SH3 domain-containing protein START domain-containing protein Serine/threonine-protein kinase SULU Serine/threonine-protein kinase max-2 Serine/threonine-protein kinase mrck-1 Serine/threonine-protein kinase pak-1 Serine/threonine-protein kinase pak-2 Son of sevenless homolog Synaptobrevin-1 Synaptosomal-associated protein Target of ERK kinase mpk-1 Tyrosine-protein kinase abl-1 Uncharacterized integrin beta-like protein C05D9.3 Unconventional myosin-IXa-like Vang-like protein WAPL domain-containing protein WW domain-containing protein tag-325 Wiskott-Aldrich syndrome protein family member non-specific serine/threonine protein kinase non-specific serine/threonine protein kinase protein kinase C t-SNARE protein aex-4	A0A0K3AQN0 A0A0K3AR51 A0A2K5AU23 A0A4V0ILM7 A5PEW5 A5Z2X2 F0IWT2 G5EDP9 G5EDU3 G5EEN3 G5EEN8 G5EF62 G5EF80 G5EFE1 G5EFU0 G5EGQ3 H2KY90 H2KYI7 H2KZH5 H2KZV4 H2KZV6 O01583 O01847 O02495 O17772 O17905 O18210 O44518 O45611 O61460 O61528 P03949 P34288 P34489 P46549 P46941 P55163 P91406 Q03206 Q05062 Q10901 Q10929 Q17850 Q18685 Q18879 Q19370 Q19467 Q19572 Q20440 Q20487 Q20496 Q21025 Q21341 Q21353 Q21430 Q21751 Q22682 Q23130 Q23146 Q45FX5 Q7JP75 Q86NH1 Q93332 Q94051 Q94125 Q95XW5 Q965J0 Q965N4 Q9GYK2 Q9N5D3 Q9NAN2 Q9U364 Q9UAY8 Q9XUS9 Q9XVH4 Q9XVI0 Q9XVK6 Q9XW53 U4PAK0 X5LX76	C05D9.3 CELE_F22G12.5 CELE_F23H11.4 CELE_F46H5.4 CELE_T04C9.1 CELE_Y57G11C.1147 PLD aap-1 abi-1 abl-1 aex-4 age-1 cav-1 cav-2 cdc-42 ced-10 ced-5 cgef-1 chin-1 citk-1 citk-2 cyk-1 cyk-4 ect-2 ephx-1 fozi-1 frm-3 gap gcp-2.1 gcp-2.2 gei-1 gex-2 gex-3 git-1 glt-1 glt-3 glt-4 glt-5 glt-6 glt-7 gpa-12 hum-7 kin-18 let-341 let-99 magu-1 max-2 mrck-1 pac-1 pak-1 pak-2 par-6 pes-7 pix-1 pkn-1 pld-1 rab-7 rac-1 rga-1 rga-2 rga-5 rga-8 rga-9 rhgf-1 rhgf-3 rhi-1 ric-4 rlbp-1 snb-1 sos-1 spv-1 srgp-1 sulu syd-1 tag-325 tag-77 tag-81 tiam-1 toe-2 uig-1 unc-112 unc-73 vab-1 vang-1 vav-1 wve-1
MET interacts with TNS proteins	Kringle domain-containing protein Protein kinase domain-containing protein Tensin homolog Tyrosine-protein kinase receptor svh-2 Uncharacterized integrin beta-like protein C05D9.3	H2KZU7 H2L045 P91823 Q9GYK2 Q9XVQ7	C05D9.3 CELE_F11E6.8 CELE_T22A3.6 svh-2 svh-6 tag-163 tns-1
MET activates PTK2 signaling	Inactive tyrosine-protein kinase kin-32 Integrin alpha ina-1 Integrin alpha pat-2 Kringle domain-containing protein Multiple epidermal growth factor-like domains protein 6 Protein kinase domain-containing protein Tyrosine protein-kinase src-1 Tyrosine-protein kinase receptor svh-2 Uncharacterized integrin beta-like protein C05D9.3	G5EE56 G5EFX3 H2KZU7 P34446 P91823 Q03600 Q95YD4 Q9GYK2 Q9XVQ7	C05D9.3 CELE_F11E6.8 CELE_T22A3.6 CELE_Y64G10A.7 ina-1 kin-32 pat-2 src-1 svh-2
VEGFA-VEGFR2 Pathway	BEN domain-containing protein Cell division control protein 42 homolog Discoidin domain-containing receptor tyrosine kinase B Heat shock protein 12.6 Heat shock protein Hsp-12.2 Heat shock protein Hsp-16.1/Hsp-16.11 Heat shock protein Hsp-16.41 Heat shock protein Hsp-16.48/Hsp-16.49 Heat shock protein hsp-16.2 Heat-shock protein 12.1 Inactive tyrosine-protein kinase kin-32 Integrin alpha pat-2 Integrin beta pat-3 MAP kinase-activated protein kinase mak-1 MAP kinase-activated protein kinase mak-2 Mitogen-activated protein kinase pmk-1 Mitogen-activated protein kinase pmk-2 Mitogen-activated protein kinase pmk-3 NCK (Non-Catalytic region of tyrosine Kinase) adaptor protein family Phosphatidylinositol 3-kinase age-1 Phosphoinositide 3-kinase adapter subunit Protein kinase domain-containing protein Protein kinase domain-containing protein Protein kinase domain-containing protein Protein kinase domain-containing protein Protein kinase domain-containing protein Protein kinase domain-containing protein Protein kinase domain-containing protein Protein kinase domain-containing protein Protein kinase domain-containing protein Protein vav-1 Ras-like GTP-binding protein rhoA Ras-related protein ced-10 Rho-associated protein kinase let-502 SH2 domain-containing protein SH2 domain-containing protein SHSP domain-containing protein SHSP domain-containing protein SHSP domain-containing protein SHSP domain-containing protein SHSP domain-containing protein SHSP domain-containing protein Serine/threonine-protein kinase max-2 Serine/threonine-protein kinase pak-1 Stress-induced protein 1 Tyrosine protein-kinase src-1 Tyrosine-protein kinase receptor svh-2 Uncharacterized integrin beta-like protein C05D9.3 cAMP-dependent protein kinase catalytic subunit	A0A1I6CMA1 B0M0L8 G5EDP9 G5EE36 G5EE56 G5EE62 G5EE65 G5EF99 G5EFV1 G5EGQ3 H2KZU7 K8ESG0 O44514 P02513 P06581 P06582 P21137 P34328 P34446 P34696 P91267 P92199 Q03206 Q05062 Q17446 Q17850 Q19227 Q19228 Q20164 Q20363 Q20660 Q21046 Q21360 Q22038 Q27874 Q45FX5 Q8MXI4 Q93344 Q94125 Q95PX0 Q95XA9 Q95YD4 Q95ZV7 Q965G5 Q9GYK2 Q9U3L3 Q9XVQ7 Q9XX60 Q9XXC0	C05D9.3 C49C3.10 CELE_F08H9.3 CELE_F08H9.4 CELE_F11E6.8 CELE_F12F6.1 CELE_F13B12.6 CELE_F21F3.2 CELE_F59F5.3 CELE_Y106G6D.4 CELE_Y106G6E.1 CELE_Y51B9A.9 CELE_ZK1128.7 aap-1 age-1 cdc-42 ced-10 ddr-2 gap-3 gska-3 gskl-2 hsp-12.1 hsp-12.2 hsp-12.3 hsp-12.6 hsp-16 hsp-16.1 hsp-16.11 hsp-16.2 hsp-16.41 hsp-16.48 hsp-16.49 hsp-17 hsp-43 hsp12-2 hsp16-1a hsp16-1b hsp16-2 hsp16-41 hsp16-48 hsp16-48a hsp16-48b hsp16-49 kin-1 kin-32 kin-36 let-502 mak-1 mak-2 max-2 nck-1 pak-1 pat-2 pat-3 pmk-1 pmk-2 pmk-3 rac-1 rho-1 rhoa sip-1 src-1 svh-2 svh-4 vav-1
Smooth Muscle Contraction	Aldehyde dehydrogenase domain-containing protein EF-hand domain-containing protein EF-hand domain-containing protein EF-hand domain-containing protein FERM domain-containing protein Integrin alpha pat-2 Integrin beta pat-3 Myosin regulatory light chain 1 Myosin regulatory light chain 2 Myosin regulatory light chain Myosin, essential light chain Myosin-11 Myosin-11 Myosin-2 essential light chain SH3 domain-containing protein Sorbin and SH3 domain-containing protein 1 homolog Tropomodulin Tropomodulin Tropomyosin isoforms a/b/d/f Uncharacterized integrin beta-like protein C05D9.3 Vinculin	G5EBY3 G5EC32 G5EGK1 O01479 P19625 P19626 P19826 P34446 P53014 Q09510 Q18501 Q20238 Q20641 Q20780 Q21201 Q22866 Q27874 Q69Z12 Q8I7M7 Q9GYK2 Q9XVI9	C05D9.3 C36E8.4 alh-1 cal-7 deb-1 lev-11 mlc-1 mlc-2 mlc-3 mlc-4 mlc-5 mlc-6 mlc-7 nmy-1 nmy-2 pat-2 pat-3 sorb-1 tln-1 tmd-1 tmd-2 tmy-1 unc-94
Fibronectin matrix formation	Fibronectin type-III domain-containing protein Integrin alpha pat-2 Uncharacterized integrin beta-like protein C05D9.3	P34446 Q18096 Q9GYK2	C05D9.3 C18E9.7 pat-2
GRB2:SOS provides linkage to MAPK signaling for Integrins	Abnormal cell migration protein 10 FERM domain-containing protein Fibronectin type-III domain-containing protein Inactive tyrosine-protein kinase kin-32 Integrin alpha pat-2 Integrin beta pat-3 Ras-related protein Rap-1 Sex muscle abnormal protein 5 Son of sevenless homolog Tyrosine protein-kinase src-1 Uncharacterized integrin beta-like protein C05D9.3	G5EE56 G5EGK1 P29355 P34400 P34446 Q18096 Q18246 Q27874 Q95YD4 Q9GYK2 Q9N5D3	C05D9.3 C18E9.7 kin-32 let-341 mig-10 pat-2 pat-3 rap-1 sem-5 sos-1 src-1 tln-1
MAP2K and MAPK activation	14-3-3-like protein 1 14-3-3-like protein 2 Abnormal cell migration protein 10 Beta-arrestin arr-1 Calponin-homology (CH) domain-containing protein Connector enhancer of kinase suppressor of ras Dual specificity mitogen-activated protein kinase kinase mek-2 FERM domain-containing protein Fibronectin type-III domain-containing protein Integrin alpha pat-2 Integrin beta pat-3 Interleukin cytokine receptor-related protein 2 Kinase suppressor of Ras A Kinase suppressor of Ras B Late endosomal/lysosomal adaptor and MAPK and MTOR activator 5 Mitogen-activated protein kinase mpk-1 Phosphatidylethanolamine-binding protein homolog F40A3.3 Raf homolog serine/threonine-protein kinase Ragulator complex protein LAMTOR2 homolog Ras protein let-60 Ras-related protein Rap-1 Serine/threonine-protein kinase par-1 Tyrosine protein-kinase src-1 Tyrosine-protein kinase csk-1 Uncharacterized integrin beta-like protein C05D9.3 Vinculin WD repeat domain-containing protein 83	G5ECJ6 G5EDA5 G5EE56 G5EEW9 G5EFD2 G5EGK1 O16264 O17772 P19826 P22981 P34400 P34446 P39745 P41932 P51485 Q07292 Q10128 Q10664 Q18096 Q18246 Q19986 Q20655 Q27874 Q8WQG5 Q9GYK2 Q9N2U6 Q9TW45	C05D9.3 C18E9.7 F40A3.3 arr-1 cnk-1 csk-1 deb-1 ftt-1 ftt-2 ilcr-2 ksr-1 ksr-2 let-60 lin-34 lin-45 lmtr-2 lmtr-3 mek-2 mig-10 mpk-1 par-1 par-5 pat-2 pat-3 pes-7 raf-1 rap-1 src-1 sur-1 tln-1 wdr-83
Integrin cell surface interactions	Collagen alpha-1(IV) chain Collagen alpha-2(IV) chain Contactin rig-6 Discoidin domain-containing receptor tyrosine kinase B Fibronectin type-III domain-containing protein Ig-like domain-containing protein Integrin alpha ina-1 Integrin alpha pat-2 Integrin beta pat-3 Protein kinase domain-containing protein Protein kinase domain-containing protein Titin homolog Uncharacterized integrin beta-like protein C05D9.3	A0A1I6CMA1 C6KRM7 G4SLH0 H2KZ60 P17139 P17140 P34446 Q03600 Q18096 Q21046 Q27874 Q95ZV7 Q9GYK2	C05D9.3 C18E9.7 CELE_F59F5.3 clb-1 clb-2 ddr-2 emb-9 ina-1 kin-36 let-2 pat-2 pat-3 rig-5 rig-6 svh-4 ttn-1
Cell surface interactions at the vascular wall	Fibronectin type-III domain-containing protein Golgi apparatus protein 1 homolog Integrin alpha pat-2 Sushi domain-containing protein Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 Uncharacterized integrin beta-like protein C05D9.3	A0A1N7SYP5 P34446 Q18096 Q18849 Q19459 Q9GYK2	C05D9.3 C18E9.7 C54G4.4 F14E5.2 cfh-1 pat-2

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