Acrosome Reaction and Sperm:Oocyte Membrane Binding
|
|
|
- ACR
- CD9
- IZUMO1
- IZUMO2
- IZUMO3
- IZUMO4
|
|
ABC-family proteins mediated transport
|
|
|
- ABCA4
- ABCB1
- ABCB4
- ABCB9
- ABCC1
- ABCC10
- ABCC11
- ABCC2
- ABCC3
- ABCC5
- ABCC9
- ABCF1
- ABCR
- ADRM1
- CFTR
- DERL1
- DERL2
- DERL3
- EIF2A
- EIF2S1
- EIF2S2
- EIF2S3
- ERLEC1
- ERLIN1
- ERLIN2
- KCNJ11
- LOC515333
- MRP1
- OS9
- PSMA1
- PSMA2
- PSMA3
- PSMA4
- PSMA5
- PSMA6
- PSMA7
- PSMB1
- PSMB2
- PSMB3
- PSMB4
- PSMB5
- PSMB6
- PSMB7
- PSMC2
- PSMC3
- PSMC4
- PSMC5
- PSMC6
- PSMD1
- PSMD11
- PSMD12
- PSMD13
- PSMD14
- PSMD2
- PSMD3
- PSMD6
- PSMD7
- PSMD8
- RNF185
- RNF5
- RPS27A
- SEL1L
- SPFH2
- SUG1
- TRAP2
- UBA52
- UBA80
- UBB
- UBC
- UBCEP1
- UBCEP2
- VCP
|
|
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A
|
|
|
- ADRM1
- CDC25A
- CHEK2
- PSMA1
- PSMA2
- PSMA3
- PSMA4
- PSMA5
- PSMA6
- PSMA7
- PSMB1
- PSMB2
- PSMB3
- PSMB4
- PSMB5
- PSMB6
- PSMB7
- PSMC2
- PSMC3
- PSMC4
- PSMC5
- PSMC6
- PSMD1
- PSMD11
- PSMD12
- PSMD13
- PSMD14
- PSMD2
- PSMD3
- PSMD6
- PSMD7
- PSMD8
- RPS27A
- SUG1
- TRAP2
- UBA52
- UBA80
- UBB
- UBC
- UBCEP1
- UBCEP2
|
|
Classical antibody-mediated complement activation
|
|
|
- ADIB
- C1QA
- C1QB
- C1R
- C1S
- CRP
|
|
Cell surface interactions at the vascular wall
|
|
|
- AMICA1
- APOB
- CAR
- CD177
- CD18
- CD2
- CD44
- CD47
- CD48
- CD58
- CD74
- CD84
- CEACAM1
- CXADR
- EPCAM
- EPCR
- ESAM
- F11R
- F2
- FCAMR
- FCER1G
- FN1
- FYN
- GAS6
- GLG1
- GPC1
- IGJ
- ITGA4
- ITGAL
- ITGAM
- ITGAX
- ITGB1
- ITGB2
- JAM1
- JAM2
- LOC112442324
- LYN
- MERTK
- MIF
- OLR1
- PECAM1
- PPBP
- PROC
- PROCR
- PROS
- PROS1
- SDC1
- SDC2
- SDC4
- SELE
- SELP
- SIRPA
- SIRPB1
- SPN
- TGFB1
- THBD
- TREM1
|
|
Ion transport by P-type ATPases
|
|
|
- ATP10A
- ATP10B
- ATP10D
- ATP11A
- ATP11B
- ATP11C
- ATP12A
- ATP13A1
- ATP13A2
- ATP13A4
- ATP13A5
- ATP1A1
- ATP1A2
- ATP1A3
- ATP1A4
- ATP1B1
- ATP1B2
- ATP1B3
- ATP2A1
- ATP2A2
- ATP2A3
- ATP2B1
- ATP2B2
- ATP2B3
- ATP2B4
- ATP2C1
- ATP2C2
- ATP4A
- ATP4B
- ATP8A1
- ATP8A2
- ATP8B1
- ATP8B2
- ATP8B3
- ATP8B4
- ATP9A
- ATP9B
- CALM
- CAMK2A
- CAMK2B
- CAMK2D
- FXYD1
- FXYD2
- FXYD4
- FXYD6
- FXYD7
- PLM
- PLN
- SPCA
- SRI
|
|
Glutathione synthesis and recycling
|
|
|
- CHAC1
- CHAC2
- CNDP2
- GCLC
- GCLM
- GGCT
- GGT1
- GGT5
- GGT7
- GGTL3
- GSS
|
|
Clathrin-mediated endocytosis
|
|
|
- AAK1
- ACTR2
- ACTR3
- ADRB2
- AGTR1
- AMPH
- AP2A1
- AP2A2
- AP2B1
- AP2M1
- AP2S1
- APOB
- AREG
- ARFGAP1
- ARP2
- ARP3
- ARPC1A
- ARPC2
- ARPC3
- ARPC4
- ARPC5
- ARRB1
- ARRB2
- AVP
- AVPR2
- BIN1
- BTC
- CBL
- CD3D
- CD3G
- CD4
- CFTR
- CHRM2
- CLTA
- CLTB
- CLTC
- CLTLB
- DAB2
- DNAJC6
- DNM1
- DNM3
- DVL2
- EGFR
- EPGN
- EPN1
- EPN2
- EPS15
- EPS15L1
- EREG
- FCHO1
- FCHO2
- FNBP1
- FNBP1L
- GAK
- GAPVD1
- GRB2
- HBEGF
- HGS
- HIP1
- HIP1R
- HSC70
- HSPA8
- IGF2R
- IL7R
- ITSN1
- ITSN2
- KIAA0319
- LDLR
- LDLRAP1
- LRP2
- M6PR
- NECAP1
- NECAP2
- OCRL
- PACSIN1
- PACSIN2
- PACSIN3
- PIK3C2A
- PIP5K1C
- RAB5A
- RAB5B
- REPS1
- RPS27A
- SCARB2
- SH3GL1
- SH3GL2
- SH3GL3
- SH3KBP1
- SLC18A3
- SLC2A8
- SNAP91
- SNX18
- SNX9
- STAM
- STAM2
- STON1
- STON2
- SYB2
- SYNJ2
- SYT1
- SYT11
- SYT8
- SYT9
- TACR1
- TF
- TFRC
- TGFA
- TRIP10
- UBA52
- UBA80
- UBB
- UBC
- UBCEP1
- UBCEP2
- VAMP2
- VAMP4
- VAMP8
- WASL
- WNT5A
|
|
Mitochondrial unfolded protein response (UPRmt)
|
|
|
- DNAJA1
- ESR
- ESR1
- FOXO3
- HSF1
- HSP70-1
- HSPA1A
- NR3A1
- SIRT3
|
|
SHC-related events triggered by IGF1R
|
|
|
- GRB2
- IGF1
- IGF1R
- IGF2
- SHC1
- SOS1
|
|
Downregulation of TGF-beta receptor signaling
|
|
|
- BAMBI
- MTMR4
- RPS27A
- SMAD2
- SMAD3
- SMAD7
- SMURF2
- STRAP
- STUB1
- TGFB1
- TGFBR1
- TGFBR2
- UBA52
- UBA80
- UBB
- UBC
- UBCEP1
- UBCEP2
|
|
Acyl chain remodelling of PI
|
|
|
- CPLA2
- LENG4
- LOC613966
- MBOAT7
- OACT7
- PLA2G12A
- PLA2G16
- PLA2G1B
- PLA2G2A
- PLA2G2D1
- PLA2G2E
- PLA2G4
- PLA2G4A
- PLA2G4D
- PLA2G4E
- PLA2G4F
- PLA2R1
- PLBD1
|
|
RAC3 GTPase cycle
|
|
|
- ABI1
- ABI2
- ABL2
- ABR
- AMIGO2
- ARAP2
- ARAP3
- ARHGAP1
- ARHGAP15
- ARHGAP17
- ARHGAP26
- ARHGAP32
- ARHGAP35
- ARHGAP39
- ARHGAP42
- ARHGAP5
- ARHGAP6
- ARHGDIB
- ASCT2
- BAIAP2
- BAIAP2L1
- BCR
- BORG5
- C22H3ORF10
- CAV1
- CDC42
- CDC42EP1
- CYBA
- CYBB
- CYFIP1
- DEPDC1B
- DIAPH3
- DOCK10
- DSG2
- EMD
- EPHA2
- ERP27
- FAM62A
- FERMT2
- GARRE1
- GIT1
- GIT2
- HSPC321
- ITGB1
- JAG1
- LAMTOR1
- LBR
- LMAN1
- MCAM
- MPP7
- NCF1
- NCF2
- NCF4
- NCKAP1L
- NHS
- NOX1
- NOX3
- NOXO1
- OCRL
- OPHN1
- PAK1
- PAK2
- PAK4
- PGRMC2
- PIK3R1
- PIK3R2
- PREX1
- RAC3
- RACGAP1
- RAPGEF1
- RBM39
- SLC1A5
- SLITRK3
- SLITRK5
- SNAP23
- SRGAP2
- STBD1
- SWAP70
- SYDE1
- TAOK3
- TFRC
- TRIO
- VANGL1
- VAV2
- VRK2
- WASF1
- WASF2
- YKT6
|
|
Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation
|
|
|
- F8
- FN3KRP
- ICMT
- TPST1
- TPST2
|
|
TGF-beta receptor signaling activates SMADs
|
|
|
- CBL
- FKBP1
- FKBP1A
- FURIN
- ITGAV
- ITGB1
- ITGB3
- ITGB5
- ITGB6
- ITGB8
- LTBP1
- LTBP2
- LTBP3
- LTBP4
- NEDD8
- SMAD2
- SMAD3
- SMAD4
- TGFB1
- TGFB2
- TGFB3
- TGFBR1
- TGFBR2
- TGFBR3
- UBC12
- UBE2M
- ZFYVE9
|
|
Activation of C3 and C5
|
|
|
- BF
- C2
- C3
- C4A
- C5
- CFB
- LOC107131209
|
|
Pyroptosis
|
|
|
- BAK1
- BAX
- CASP1
- CASP13
- CASP3
- CHMP2A
- CHMP2B
- CHMP3
- CHMP4A
- CHMP4B
- CHMP4C
- CHMP6
- CHMP7
- CYC
- CYCS
- ELANE
- GSDMD
- GSDME
- GZMB
- HMG1
- HMGB1
- IGIF
- IL18
- IL1A
- IL1B
- VPS24
|
|
SHC-mediated cascade:FGFR3
|
|
|
- AFGF
- FGF1
- FGF16
- FGF17
- FGF18
- FGF2
- FGF20
- FGF23
- FGF4
- FGF4A
- FGF4C
- FGF5
- FGF6A
- FGF8
- FGF9
- FGFA
- FGFR3
- Fgf4
- GRB2
- HBGF-1
- KRAS
- NRAS
- SHC1
- SOS1
|
|
Transport of inorganic cations/anions and amino acids/oligopeptides
|
|
|
- CTNS
- EAAT1
- GLAST
- GLAST1
- SAMC
- SLC1A1
- SLC1A2
- SLC1A3
- SLC1A6
- SLC1A7
- SLC25A26
- SLC32A1
|
|
Degradation of the extracellular matrix
|
|
|
- ACAN
- ADAM10
- ADAM15
- ADAMTS4
- ADAMTS5
- BCAN
- BSG
- CAPN1
- CAPN10
- CAPN12
- CAPN13
- CAPN14
- CAPN2
- CAPN3
- CAPN4
- CAPN5
- CAPN6
- CAPN7
- CAPN8
- CAPNS1
- CAST
- CD44
- CDH1
- CTSK
- CTSL
- CTSL1
- CTSS
- DCN
- ELANE
- HTRA1
- KLK7
- LOC112441463
- LOC509956
- MADM
- MMP12
- MMP13
- MMP14
- MMP19
- MMP2
- MMP3
- MMP7
- MMP8
- MMP9
- NID1
- OPT
- OPTC
- SCUBE1
- SCUBE3
- SPP1
- TMPRSS6
|
|
Regulation of CDH11 function
|
|
|
- ADAM19
- ADAM33
- AMOT
- ANGPTL4
- CDH11
- CTNNB1
- CTNND1
- JUP
|
|
COPII-mediated vesicle transport
|
|
|
- ANKRD28
- AREG
- BET1
- CD59
- CNIH
- CNIH1
- CSNK1D
- CTSC
- CTSZ
- F5
- F8
- FOLR3
- GOLGA2
- GORASP1
- GOSR2
- GRIA1
- HCKID
- LMAN1
- LMAN1L
- LMAN2
- LMAN2L
- MCFD2
- NAPA
- NAPB
- NAPG
- NSF
- PI
- PPP6C
- PPP6R1
- PPP6R3
- PREB
- RAB1A
- RAB1B
- SAPS3
- SAR1B
- SCFD1
- SEC13
- SEC13L1
- SEC16A
- SEC16B
- SEC22A
- SEC22B
- SEC22C
- SEC23A
- SEC23IP
- SEC24A
- SEC24B
- SEC24C
- SEC24D
- SEC31A
- SEC31B
- SERPINA1
- SNAPB
- STX17
- STX5
- TBC1D20
- TFG
- TGFA
- TMED10
- TMP21
- TRAPPC1
- TRAPPC10
- TRAPPC2
- TRAPPC2L
- TRAPPC3
- TRAPPC4
- TRAPPC5
- TRAPPC6A
- TRAPPC6B
- TRAPPC9
- USO1
- VDP
- VIPL
- YKT6
|
|
EPH-ephrin mediated repulsion of cells
|
|
|
- APH1A
- APH1B
- EFNB1
- EFNB2
- EFNB3
- EPHB1
- EPHB2
- EPHB3
- EPHB4
- EPHB6
- FYN
- LYN
- MMP2
- MMP9
- NCSTN
- PEN2
- PSEN1
- PSEN2
- PSENEN
- SRC
- VAV2
- VAV3
- YES1
|
|
KEAP1-NFE2L2 pathway
|
|
|
- ADRM1
- CUL3
- KEAP1
- MAP1ALC3
- MAP1LC3
- MAP1LC3B
- MUL1
- NFE2L2
- NPLOC4
- PRKCI
- PSMA1
- PSMA2
- PSMA3
- PSMA4
- PSMA5
- PSMA6
- PSMA7
- PSMB1
- PSMB2
- PSMB3
- PSMB4
- PSMB5
- PSMB6
- PSMB7
- PSMC2
- PSMC3
- PSMC4
- PSMC5
- PSMC6
- PSMD1
- PSMD11
- PSMD12
- PSMD13
- PSMD14
- PSMD2
- PSMD3
- PSMD6
- PSMD7
- PSMD8
- RPS27A
- SESN1
- SESN2
- SQSTM1
- SUG1
- TRAP2
- TRIM21
- UBA52
- UBA80
- UBB
- UBC
- UBCEP1
- UBCEP2
- UBXN7
- UFD1
- VCP
|
|
Platelet Aggregation (Plug Formation)
|
|
|
|
|