Regulation of TLR by endogenous ligand

Summary
Species
Homo sapiens
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
TLR4:LY96HMGB1:TLR4:MD2DEFHC23,45-HMGB1:LPSLPSLTAHC23,45-HMGB1:LTASFTPA oligomer, SFTPD oligomerSP-A/SP-D:TLR4:MD2TLR1:TLR2SFTPA/SFTPD:TLR2:TLR1TLR4:MD2:calprotectincalprotectinS100A1:TLR4:LY96S100A1 dimer:Ca(2+)oxidised phospholipidCD14:oxPLCD14(20-345)LBPLBP:oxPLTLR4:TLR6TLR4:TLR6:CD36:oxLDLoxLDL:CD36TLR4:LY96:cleaved fibrinogenFGA, FGB, FGGG analogG analog:C-ter TLR7 dimerC-ter TLR7 dimerHMGB1
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
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International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: April 7, 2025