GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **226 - 250** of **268** in total

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Pathway Name	Protein Name ▼	UniProt ID	Gene Symbol	Organism	GlyTouCan ID
Glycolysis	ADP dependent glucokinase ATP-dependent 6-phosphofructokinase ATP-dependent 6-phosphofructokinase ATP-dependent 6-phosphofructokinase Beta-enolase Enolase 4 Fructose-bisphosphate aldolase Fructose-bisphosphate aldolase Fructose-bisphosphate aldolase Glucosamine-6-phosphate isomerase Glucosamine-6-phosphate isomerase Glucose-6-phosphate isomerase Glyceraldehyde-3-phosphate dehydrogenase Glyceraldehyde-3-phosphate dehydrogenase Glyceraldehyde-3-phosphate dehydrogenase Glyceraldehyde-3-phosphate dehydrogenase Hexokinase-1 Hexokinase-2 Phosphoglucomutase 2 like 1 Phosphoglycerate kinase Phosphoglycerate kinase Phosphoglycerate mutase Phosphoglycerate mutase Phosphoglycerate mutase Phosphotransferase Pyruvate kinase PKLR Triosephosphate isomerase hexokinase hexokinase phosphopyruvate hydratase phosphopyruvate hydratase	A0A8I3MJP4 A0A8I3MK58 A0A8I3MKD5 A0A8I3MKW3 A0A8I3MLI6 A0A8I3MVF3 A0A8I3MYU3 A0A8I3N1E7 A0A8I3N4J1 A0A8I3N504 A0A8I3N9R0 A0A8I3NII5 A0A8I3NIY6 A0A8I3NMJ6 A0A8I3NTY8 A0A8I3P147 A0A8I3P1K1 A0A8I3P2U1 A0A8I3P7P5 A0A8I3P9Y9 A0A8I3PRM7 A0A8I3PU48 A0A8I3PVY7 A0A8I3PZE8 A0A8I3Q5N9 A0A8I3Q5Z0 A0A8I3RRW0 A0A8I3RWL6 A0A8I3S3G1 A0A8I3SC19 Q29536	ADPGK ALDOA ALDOB ALDOC BPGM ENO2 ENO3 ENO4 GAPDH GAPDHS GCK GNPDA1 GNPDA2 GPI HK1 HK2 HK3 HKDC1 LOC106558132 PFKL PFKM PFKP PGAM1 PGAM2 PGK1 PGK2 PGM2L1 PKLR TPI1	Canis familiaris (dog)	G58161NS
Platelet Adhesion to exposed collagen	ADAM metallopeptidase with thrombospondin type 1 motif 13 High affinity immunoglobulin epsilon receptor subunit gamma Tyrosine-protein kinase Tyrosine-protein kinase Uncharacterized protein von Willebrand factor von Willebrand factor	A0A8I3N060 A0A8I3NAX6 A0A8I3P3X1 A0A8I3PUN0 A0A8I3QSK6 A0A8I3SCK0 Q28295	ADAMTS13 F8VWF FCER1G FYN GP6 LYN VWF	Canis familiaris (dog)
TNF signaling	ADAM metallopeptidase domain 17 Receptor interacting serine/threonine kinase 1 TNF receptor-associated factor TNFR-Cys domain-containing protein Tumor necrosis factor receptor type 1-associated DEATH domain protein Tumor necrosis factor	A0A8I3MQC7 A0A8I3NEJ2 A0A8I3PPY4 A0A8I3Q3L1 A0A8I3S2L7 P51742	ADAM17 RIPK1 TNF TNFA TNFRSF1A TNFSF2 TRADD TRAF2	Canis familiaris (dog)
Heme degradation	ABC-type glutathione-S-conjugate transporter Albumin Biliverdin reductase A Broad substrate specificity ATP-binding cassette transporter ABCG2 Fatty acid-binding protein, liver Glutathione S-transferase Heme oxygenase 1 Multidrug resistance-associated protein 1 Multidrug resistance-associated protein 1 Solute carrier organic anion transporter family member Solute carrier organic anion transporter family member heme oxygenase (biliverdin-producing)	A0A8I3MH42 A0A8I3MY68 A0A8I3N1I8 A0A8I3N2D2 A0A8I3ND57 A0A8I3NLZ5 A0A8I3NMC0 A0A8I3NUI6 A0A8I3RX41 A0A8I3SCV5 B3RFJ1 Q6UR05	ABCC1 ABCC2 ABCG2 ALB Abcg2 BLVRA FABP1 HMOX1 HMOX2 LOC474938 MRP1 SLCO1B2 SLCO1B3 SLCO2B1	Canis familiaris (dog)
Atorvastatin ADME	ABC-type glutathione-S-conjugate transporter ATP binding cassette subfamily B member 1 Cytochrome P450 3A12 Cytochrome P450 3A Cytochrome P450 3A Cytochrome P450 3A Paraoxonase 3 Paraoxonase Solute carrier organic anion transporter family member Solute carrier organic anion transporter family member	A0A8I3MQC6 A0A8I3N2I4 A0A8I3NMC0 A0A8I3NUI6 A0A8I3PAM3 A0A8I3PDF6 A0A8I3PU35 A0A8I3PV37 A0A8I3SCV5 P24463	ABCB1 ABCC2 CYP3A12 LOC119868939 LOC119875773 LOC119876349 PON1 PON3 SLCO1B2 SLCO1B3 SLCO2B1	Canis familiaris (dog)
Recycling of bile acids and salts	ABC-type glutathione-S-conjugate transporter Albumin Bile acid-CoA Bile salt export pump Ileal sodium/bile acid cotransporter Nuclear receptor coactivator Nuclear receptor coactivator Nuclear receptor subfamily 1 group H member 4 Retinoic acid receptor RXR Solute carrier family 10 member 1 Solute carrier family 51 subunit alpha Solute carrier family 51 subunit beta Solute carrier organic anion transporter family member Solute carrier organic anion transporter family member StAR related lipid transfer domain containing 5 long-chain-fatty-acid--CoA ligase	A0A8I3MAI7 A0A8I3MLS9 A0A8I3MY68 A0A8I3N1E1 A0A8I3N2S7 A0A8I3NIH7 A0A8I3NUI6 A0A8I3NXT1 A0A8I3PI53 A0A8I3PRC4 A0A8I3PYI4 A0A8I3Q2C1 A0A8I3RTD6 A0A8I3S0X8 B8K1W2 Q70HQ9	ABCC3 ALB Abcb11e BAAT BSEP NCOA1 NCOA2 NR1H4 RXRA SLC10A1 SLC10A2 SLC27A5 SLC51A SLC51B SLCO1A2 SLCO1B2 SLCO1B3 STARD5 slc10a2	Canis familiaris (dog)
APAP ADME	ABC-type glutathione-S-conjugate transporter ABC-type glutathione-S-conjugate transporter ATP binding cassette subfamily C member 4 ATP binding cassette subfamily C member 5 Broad substrate specificity ATP-binding cassette transporter ABCG2 Cytochrome P450 2E1 Cytosolic non-specific dipeptidase Gamma-glutamyltransferase 6 Glutathione S-transferase Glutathione S-transferase Glutathione hydrolase Glutathione hydrolase Glutathione transferase Multidrug resistance-associated protein 1 Multidrug resistance-associated protein 1 N-acyl-aliphatic-L-amino acid amidohydrolase Sulfotransferase 1A1 Sulfotransferase Sulfotransferase glucuronosyltransferase glucuronosyltransferase glucuronosyltransferase	A0A8I3MEU4 A0A8I3MEX7 A0A8I3N072 A0A8I3N1I8 A0A8I3N279 A0A8I3N2I7 A0A8I3NBB4 A0A8I3NE83 A0A8I3P300 A0A8I3PHP8 A0A8I3PSW5 A0A8I3PVZ3 A0A8I3QRM6 A0A8I3QUB8 A0A8I3S0X8 A0A8I3S4W3 A0A8I3SCV5 B3RFJ1 B8K1W7 Q29476 Q6UR05 Q9MZY0	ABCC1 ABCC2 ABCC3 ABCC4 ABCC5 ABCG2 ABHD14A Abcc4 Abcg2 CNDP2 CYP2E1 GGT1 GGT6 GGT7 GSTP1 LOC119874463 LOC119876946 MRP1 SULT1A1 SULT1C4 SULT1E1 UGT1A6	Canis familiaris (dog)
O-glycosylation of TSR domain-containing proteins	A disintegrin and metalloproteinase with thrombospondin motifs 4 ADAM metallopeptidase with thrombospondin type 1 motif 10 ADAM metallopeptidase with thrombospondin type 1 motif 12 ADAM metallopeptidase with thrombospondin type 1 motif 13 ADAM metallopeptidase with thrombospondin type 1 motif 14 ADAM metallopeptidase with thrombospondin type 1 motif 16 ADAM metallopeptidase with thrombospondin type 1 motif 17 ADAM metallopeptidase with thrombospondin type 1 motif 18 ADAM metallopeptidase with thrombospondin type 1 motif 19 ADAM metallopeptidase with thrombospondin type 1 motif 1 ADAM metallopeptidase with thrombospondin type 1 motif 20 ADAM metallopeptidase with thrombospondin type 1 motif 2 ADAM metallopeptidase with thrombospondin type 1 motif 3 ADAM metallopeptidase with thrombospondin type 1 motif 5 ADAM metallopeptidase with thrombospondin type 1 motif 6 ADAM metallopeptidase with thrombospondin type 1 motif 8 ADAM metallopeptidase with thrombospondin type 1 motif 9 ADAMTS like 1 ADAMTS like 2 ADAMTS like 4 Beta 3-glucosyltransferase Complement factor properdin GDP-fucose protein O-fucosyltransferase 2 NTR domain-containing protein SCO-spondin Semaphorin 5A Semaphorin 5B Somatomedin B and thrombospondin type 1 domain containing Spondin-1 Thrombospondin 1 Thrombospondin 2 Thrombospondin type 1 domain containing 7A Thrombospondin type 1 domain containing 7B Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein	A0A4D6CAB5 A0A8I3MD18 A0A8I3MIA8 A0A8I3MQ02 A0A8I3MRT7 A0A8I3MXQ6 A0A8I3MZ18 A0A8I3MZD5 A0A8I3N140 A0A8I3N1D3 A0A8I3N2T5 A0A8I3NA49 A0A8I3NAX6 A0A8I3NB75 A0A8I3NE19 A0A8I3NGS7 A0A8I3NK12 A0A8I3NKG0 A0A8I3NM21 A0A8I3NS78 A0A8I3P088 A0A8I3P1X0 A0A8I3P533 A0A8I3PA53 A0A8I3PBE9 A0A8I3PG52 A0A8I3PJ96 A0A8I3PJW2 A0A8I3PNR9 A0A8I3PPJ4 A0A8I3PPU8 A0A8I3PQZ5 A0A8I3PUQ0 A0A8I3Q3A2 A0A8I3Q4T9 A0A8I3Q9Y4 A0A8I3RTV1 A0A8I3S8L6	ADAMTS1 ADAMTS10 ADAMTS12 ADAMTS13 ADAMTS14 ADAMTS15 ADAMTS16 ADAMTS17 ADAMTS18 ADAMTS19 ADAMTS2 ADAMTS20 ADAMTS3 ADAMTS4 ADAMTS5 ADAMTS6 ADAMTS7 ADAMTS8 ADAMTS9 ADAMTSL1 ADAMTSL2 ADAMTSL4 ADAMTSL5 B3GLCT CFP POFUT2 SBSPON SEMA5A SEMA5B SH3GL3 SPON1 SPON2 SSPO THBS1 THBS2 THSD1 THSD7A THSD7B	Canis familiaris (dog)
Antigen Presentation: Folding, assembly and peptide loading of class I MHC	78 kDa glucose-regulated protein ABC-type antigen peptide transporter Aminopeptidase Beta-2-microglobulin Calnexin Calreticulin GTP-binding protein SAR1b Immunoglobulin C1-set domain-containing protein MHC class I DLA-12 MHC class I DLA-64 MHC class I DLA-88 MHC class Ib Protein SEC13 homolog Protein disulfide-isomerase Protein transport protein SEC23 Protein transport protein Sec31A SEC24 homolog A, COPII coat complex component SEC24 homolog B, COPII coat complex component SEC24 homolog C, COPII coat complex component SEC24 homolog D, COPII coat complex component Tapasin	A0A8I3MLY2 A0A8I3N796 A0A8I3N9C4 A0A8I3NCJ5 A0A8I3NCT5 A0A8I3NDA5 A0A8I3NM03 A0A8I3NPS2 A0A8I3NRG2 A0A8I3NSU2 A0A8I3NZH7 A0A8I3P4F9 A0A8I3P4Y2 A0A8I3PXH7 A0A8I3Q7H2 A0A8I3RR85 A0A8I3RUA9 A0A8I3S449 A0A8I3S5M8 A0A8I3SCF9 Q5TJE4	B2M CALR CANX DLA-12 DLA-79 DLA-DOB DLA88 ERAP1 HSPA5 LOC119876190 LOC119876868 PDIA3 SEC13 SEC23A SEC24A SEC24B SEC24C SEC24D SEC31A TAPBP	Canis familiaris (dog)
Extra-nuclear estrogen signaling	72 kDa type IV collagenase Caveolin-1 Caveolin-2 EGF-like domain-containing protein Epiregulin Estrogen receptor beta Estrogen receptor Focal adhesion kinase 1 G protein subunit alpha transducin 3 G protein subunit beta 2 G protein subunit beta 4 G protein subunit gamma 13 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 Guanine nucleotide-binding protein G(T) subunit gamma-T1 Guanine nucleotide-binding protein G(i) subunit alpha-1 Guanine nucleotide-binding protein G(i) subunit alpha-2 Guanine nucleotide-binding protein G(i) subunit alpha-3 Guanine nucleotide-binding protein subunit beta-5 Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Matrix metallopeptidase 7 Matrix metalloproteinase-9 Palmitoyltransferase Palmitoyltransferase Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphoinositide-3-kinase regulatory subunit 2 Phosphoinositide-3-kinase regulatory subunit 3 Pro-epidermal growth factor Proheparin-binding EGF-like growth factor Receptor protein-tyrosine kinase SHC-transforming protein 1 Sphingosine kinase 1 Sphingosine-1-phosphate receptor 3 Striatin Stromelysin-1 Tyrosine-protein kinase receptor Tyrosine-protein kinase Uncharacterized protein Uncharacterized protein Uncharacterized protein phosphatidylinositol-4,5-bisphosphate 3-kinase type I protein arginine methyltransferase	A0A5F4C2B1 A0A8I3MAV6 A0A8I3MCQ8 A0A8I3ME07 A0A8I3MGS0 A0A8I3MHA7 A0A8I3MM75 A0A8I3MN99 A0A8I3MNZ2 A0A8I3MT80 A0A8I3MYE3 A0A8I3MZG1 A0A8I3N081 A0A8I3N0H9 A0A8I3N8T5 A0A8I3N971 A0A8I3NI71 A0A8I3NMY1 A0A8I3NPA7 A0A8I3NPM9 A0A8I3NUU1 A0A8I3P3M1 A0A8I3P478 A0A8I3P519 A0A8I3P7L3 A0A8I3PJF2 A0A8I3PQY2 A0A8I3PS34 A0A8I3PV05 A0A8I3Q314 A0A8I3Q5L9 A0A8I3RPS3 A0A8I3RQ77 A0A8I3RRT3 A0A8I3RSE4 A0A8I3RYJ5 A0A8I3RYN2 A0A8I3S0D0 A0A8I3S3N2 A0A8I3S583 A0A8I3SBF9 O46550 O97564 P33724 P38400 P62872 P63210 P79147 Q6Y4Q5	AREG BTC CAV CAV-2 CAV1 CAV2 EGF EGFR EPGN EREG ESR1 ESR2 GNAI1 GNAI2 GNAI3 GNAT3 GNB1 GNB2 GNB3 GNB4 GNB5 GNG11 GNG13 GNG2 GNG3 GNG4 GNG8 GNGT1 GNGT2 HBEGF IGF1R LOC100856339 LOC119863873 MMP2 MMP3 MMP7 MMP9 PIK3CA PIK3R1 PIK3R2 PRMT1 PTK2 S1PR3 SHC1 SPHK1 SRC STRN TGFA ZDHHC21 ZDHHC7	Canis familiaris (dog)
Activation of Matrix Metalloproteinases	72 kDa type IV collagenase Cathepsin G Chymase Chymotrypsinogen 2 Collagen type XVIII alpha 1 chain Collagenase 3 Elastase, neutrophil expressed Kallikrein 1 Kallikrein B1 Kallikrein-related peptidase 2 Matrix metallopeptidase 11 Matrix metallopeptidase 15 Matrix metallopeptidase 16 Matrix metallopeptidase 17 Matrix metallopeptidase 24 Matrix metallopeptidase 25 Matrix metallopeptidase 7 Matrix metallopeptidase 8 Matrix metalloproteinase-14 Matrix metalloproteinase-9 Metalloproteinase inhibitor 1 Metalloproteinase inhibitor 2 Peptidase S1 domain-containing protein Plasminogen Procathepsin L SPARC (osteonectin), cwcv and kazal like domains proteoglycan 3 Stromelysin-1 Tryptase furin interstitial collagenase trypsin	A0A5K1VKB9 A0A8I3MCQ8 A0A8I3MF27 A0A8I3MGS0 A0A8I3MN73 A0A8I3MND9 A0A8I3MSY3 A0A8I3MWY2 A0A8I3MXC2 A0A8I3N1T9 A0A8I3N597 A0A8I3NK04 A0A8I3NM17 A0A8I3NXG0 A0A8I3P478 A0A8I3P5C4 A0A8I3PD99 A0A8I3PHE2 A0A8I3PMD6 A0A8I3PZ83 A0A8I3Q4H4 A0A8I3RPH1 A0A8I3S0N4 A0A8I3S3N5 P04813 P15944 P21842 Q6Y4Q5 Q8MJD1 Q9GL24 Q9TTY1	CMA1 COL18A1 CTRB CTRB1 CTSG CTSL CTSL1 ELA2 ELANE FURIN KLK1 KLK2 KLKB1 MMP1 MMP11 MMP13 MMP14 MMP15 MMP16 MMP17 MMP2 MMP24 MMP25 MMP3 MMP7 MMP8 MMP9 PLG PRSS2 SPOCK3 TIMP1 TIMP2	Canis familiaris (dog)
Degradation of the extracellular matrix	72 kDa type IV collagenase A disintegrin and metalloproteinase with thrombospondin motifs 4 ADAM metallopeptidase domain 15 ADAM metallopeptidase domain 8 ADAM metallopeptidase with thrombospondin type 1 motif 5 Aggrecan core protein Alpha-2-macroglobulin Basigin Brevican core protein CD44 antigen Cadherin-1 Cadherin-1 Calpain 10 Calpain 11 Calpain 12 Calpain 13 Calpain 14 Calpain 15 Calpain 5 Calpain 6 Calpain 9 Calpain catalytic domain-containing protein Calpain catalytic domain-containing protein Calpain small subunit 1 Calpain-1 catalytic subunit Calpain-2 catalytic subunit Calpain-3 Calpastatin Cathepsin G Cathepsin S Collagenase 3 Decorin Disintegrin and metalloproteinase domain-containing protein 10 Elastase, neutrophil expressed HtrA serine peptidase 1 Kallikrein D Matrix metallopeptidase 11 Matrix metallopeptidase 12 Matrix metallopeptidase 19 Matrix metallopeptidase 20 Matrix metallopeptidase 7 Matrix metallopeptidase 8 Matrix metalloproteinase-14 Matrix metalloproteinase-9 Nidogen 1 Opticin Procathepsin L Secreted phosphoprotein 1 Signal peptide, CUB domain and EGF like domain containing 1 Signal peptide, CUB domain and EGF like domain containing 3 Stromelysin-1 Transmembrane serine protease 6 interstitial collagenase	A0A8I3MCQ8 A0A8I3MDF9 A0A8I3MEZ7 A0A8I3MGS0 A0A8I3MM49 A0A8I3MND9 A0A8I3MS95 A0A8I3MTX4 A0A8I3MUT8 A0A8I3MWY2 A0A8I3MX21 A0A8I3MXC2 A0A8I3N8Z0 A0A8I3NAW1 A0A8I3NBM1 A0A8I3NET5 A0A8I3NF92 A0A8I3NG54 A0A8I3NHT2 A0A8I3NK04 A0A8I3NLH7 A0A8I3NNE0 A0A8I3NQ99 A0A8I3P0M4 A0A8I3P0U1 A0A8I3P1W2 A0A8I3P478 A0A8I3P4K7 A0A8I3P533 A0A8I3P8U9 A0A8I3PAG9 A0A8I3PCF8 A0A8I3PED9 A0A8I3PJW4 A0A8I3PMD6 A0A8I3PRM5 A0A8I3PVS1 A0A8I3Q3A2 A0A8I3Q5H9 A0A8I3QPC2 A0A8I3RPH1 A0A8I3RPK2 A0A8I3RU13 A0A8I3S3W1 A0A8I3S676 A0A8I3S9F9 A0A8I3SBJ8 E2FGH7 F1PAA9 Q29393 Q6Y4Q5 Q8MJD1 Q9GL24	A2M ACAN ADAM10 ADAM15 ADAM8 ADAMTS4 ADAMTS5 BCAN BSG CAPN1 CAPN10 CAPN11 CAPN12 CAPN13 CAPN14 CAPN15 CAPN2 CAPN3 CAPN5 CAPN6 CAPN7 CAPN8 CAPN9 CAPNS1 CAST CD44 CDH1 CTSG CTSL CTSL1 CTSS DCN DCN1C ELA2 ELANE HTRA1 KLK7 KLND MMP1 MMP11 MMP12 MMP13 MMP14 MMP19 MMP2 MMP20 MMP3 MMP7 MMP8 MMP9 NID1 OPTC SCUBE1 SCUBE3 SPP1 TMPRSS6	Canis familiaris (dog)
Pentose phosphate pathway	6-phosphogluconate dehydrogenase, decarboxylating 6-phosphogluconolactonase Glucose-6-phosphate 1-dehydrogenase Phosphoglucomutase 2 Ribokinase Ribulose-phosphate 3-epimerase Sedoheptulokinase Transaldolase Transketolase deoxyribose-phosphate aldolase ribose-5-phosphate isomerase	A0A8I3MQ54 A0A8I3MSC7 A0A8I3NN17 A0A8I3P237 A0A8I3P626 A0A8I3Q4Y1 A0A8I3Q7C5 A0A8I3RVI9 A0A8I3RZI7 A0A8I3S1Y7 A0A8I3SAK1	DERA G6PD PGD PGLS PGM2 RBKS RPE RPIA SHPK TALDO1 TKT	Canis familiaris (dog)	G31080DL
Collagen degradation	5-phosphohydroxy-L-lysine phospho-lyase 72 kDa type IV collagenase Cathepsin B Cathepsin D Collagen type XII alpha 1 chain Collagen type XIII alpha 1 chain Collagen type XIX alpha 1 chain Collagen type XV alpha 1 chain Collagen type XVIII alpha 1 chain Collagen type XXV alpha 1 chain Collagen type XXVI alpha 1 chain Collagenase 3 Matrix metallopeptidase 12 Matrix metallopeptidase 15 Matrix metallopeptidase 20 Matrix metallopeptidase 7 Matrix metallopeptidase 8 Matrix metalloproteinase-14 Matrix metalloproteinase-9 Stromelysin-1 Transmembrane serine protease 6 furin interstitial collagenase trypsin	A0A8I3MCQ8 A0A8I3MGS0 A0A8I3MJI6 A0A8I3MND9 A0A8I3MSY3 A0A8I3MWG8 A0A8I3MWY2 A0A8I3MX21 A0A8I3MXC2 A0A8I3N1T9 A0A8I3N1V6 A0A8I3N4V8 A0A8I3NL35 A0A8I3P478 A0A8I3PD99 A0A8I3PHE2 A0A8I3QKG6 A0A8I3RPH1 A0A8I3RPK2 A0A8I3RU13 A0A8I3RVF8 A0A8I3S0M3 Q4LAL9 Q6Y4Q5	COL12A1 COL13A1 COL15A1 COL18A1 COL19A1 COL25A1 COL26A1 CTSB CTSD FURIN MMP1 MMP12 MMP13 MMP14 MMP15 MMP2 MMP20 MMP3 MMP7 MMP8 MMP9 PHYKPL PRSS2 TMPRSS6	Canis familiaris (dog)
Neurotransmitter receptors and postsynaptic signal transmission	5-hydroxytryptamine receptor 3A 5-hydroxytryptamine receptor 3B 5-hydroxytryptamine receptor 3C 5-hydroxytryptamine receptor 3C 5-hydroxytryptamine receptor 3E Glycine receptor alpha 1 Glycine receptor alpha 2 Glycine receptor alpha 3 Glycine receptor beta	A0A8I3MA77 A0A8I3MAG0 A0A8I3MZA4 A0A8I3NSZ3 A0A8I3P3M8 A0A8I3PQC9 A0A8I3Q2Z5 A0A8I3Q6S9 A0A8I3S5H9	GLRA1 GLRA2 GLRA3 GLRB HTR3A HTR3B HTR3C HTR3E LOC478649	Canis familiaris (dog)
G alpha (i) signalling events	5-hydroxytryptamine receptor 1B 5-hydroxytryptamine receptor 1D 5-hydroxytryptamine receptor 1E 5-hydroxytryptamine receptor 1F 5-hydroxytryptamine receptor 5A Adenosine receptor A1 Adenosine receptor A3 Alpha-2A adrenergic receptor Alpha-2B adrenergic receptor Alpha-2C adrenergic receptor Amyloid-beta A4 protein Angiotensinogen Annexin B1 bradykinin receptor B2 bradykinin receptor Bitter taste receptor T2R43 C-C chemokine receptor type 5 C-C motif chemokine 25 C-C motif chemokine 4 C-C motif chemokine receptor 10 C-C motif chemokine receptor 7 C-C motif chemokine receptor 9 C-C motif chemokine C-C motif chemokine C-X-C chemokine receptor type 2 C-X-C chemokine receptor type 2 C-X-C chemokine receptor type 3 C-X-C chemokine receptor type 6 C-X-C motif chemokine 10 C-X-C motif chemokine 16 C-X-C motif chemokine ligand 11 C-X-C motif chemokine receptor 5 C-X-C motif chemokine C-X-C motif chemokine C-X3-C motif chemokine ligand 1 C3a anaphylatoxin chemotactic receptor C5a anaphylatoxin chemotactic receptor 1 CX3C chemokine receptor 1 Cannabinod receptor Chemokine (C-C motif) receptor 1 Complement C3 Complement C5 D(3) dopamine receptor Extracellular calcium-sensing receptor G protein signaling modulator 1 G protein signaling modulator 3 G protein subunit alpha transducin 2 G protein subunit alpha transducin 3 G protein subunit beta 2 G protein subunit beta 4 G protein subunit gamma 13 G protein-coupled receptor 17 G protein-coupled receptor 183 G protein-coupled receptor 37 like 1 G protein-coupled receptor 37 G protein-coupled receptor 55 G-protein coupled estrogen receptor 1 G-protein coupled receptor 81 G-protein coupled receptors family 1 profile domain-containing protein Galanin peptides Galanin receptor 1 Galanin receptor 2 Galanin receptor 3 Gamma-aminobutyric acid type B receptor subunit 1 Gamma-aminobutyric acid type B receptor subunit 2 Glutamate metabotropic receptor 2 Glutamate metabotropic receptor 4 Glutamate metabotropic receptor 6 Glutamate metabotropic receptor 7 Glutamate metabotropic receptor 8 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 Guanine nucleotide-binding protein G(T) subunit gamma-T1 Guanine nucleotide-binding protein G(i) subunit alpha-1 Guanine nucleotide-binding protein G(i) subunit alpha-2 Guanine nucleotide-binding protein G(i) subunit alpha-3 Guanine nucleotide-binding protein G(t) subunit alpha-1 Guanine nucleotide-binding protein subunit beta-5 Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Histamine receptor H4 Interleukin-8 Kappa-type opioid receptor Kininogen 1 Long-wave-sensitive opsin 1 Lysophosphatidic acid receptor 1 Lysophosphatidic acid receptor 2 Lysophosphatidic acid receptor 3 Lysophosphatidic acid receptor 5 Melanin concentrating hormone receptor 2 Melanin-concentrating hormone receptor 1 Melatonin receptor 1B Melatonin receptor type 1A Metabotropic glutamate receptor 3 Mu-type opioid receptor Multifunctional fusion protein Muscarinic acetylcholine receptor Muscarinic acetylcholine receptor N-arachidonyl glycine receptor Neuromedin U receptor 1 Neuromedin U receptor 2 Neuromedin-S Neuromedin-U-25 Neuropeptide B Neuropeptide W Neuropeptide Y receptor Y4 Neuropeptide Y receptor type 1 Neuropeptide Y receptor type 2 Neuropeptide Y receptor type 5 Neuropeptide Y Neuropeptides B and W receptor 1 Opioid receptor delta 1 Opsin 3 Opsin 5 Oxoglutarate receptor 1 Pancreatic polypeptide Peptide YY Pro-MCH Pro-opiomelanocortin Pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) Proenkephalin-A Proenkephalin-B Prosaposin Prostaglandin D2 receptor 2 Prostaglandin E2 receptor EP3 subtype Purinergic receptor P2Y12 Purinergic receptor P2Y14 Purkinje cell protein 2 RGS domain-containing protein Regulator of G protein signaling 11 Regulator of G protein signaling 12 Regulator of G protein signaling 13 Regulator of G protein signaling 17 Regulator of G protein signaling 18 Regulator of G protein signaling 19 Regulator of G protein signaling 21 Regulator of G protein signaling 3 Regulator of G protein signaling 5 Regulator of G protein signaling 6 Regulator of G protein signaling 7 Regulator of G-protein signaling 16 Regulator of G-protein signaling 1 Regulator of G-protein signaling 4 Regulator of G-protein signaling 8 Regulator of G-protein signaling 9 Relaxin family peptide receptor 3 Relaxin-3 Retinal G protein coupled receptor Retinal pigment epithelium-derived rhodopsin homolog Rhodopsin Short-wave-sensitive opsin 1 Somatostatin receptor 3 Somatostatin receptor 5 Somatostatin receptor type 1 Somatostatin receptor type 2 Somatostatin Sphingosine-1-phosphate receptor 2 Sphingosine-1-phosphate receptor 3 Sphingosine-1-phosphate receptor 4 Sphingosine-1-phosphate receptor 5 Succinate receptor 1 Taste 1 receptor member 1 Taste receptor type 1 member 3 Taste receptor type 2 Taste receptor type 2 Taste receptor type 2 Taste receptor type 2 Taste receptor type 2 Taste receptor type 2 Taste receptor type 2 Taste receptor type 2 Taste receptor type 2 Taste receptor type 2 Taste receptor type 2 Taste receptor type 2 Type-2 angiotensin II receptor Tyrosine-protein kinase Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein	A0A0F6TN93 A0A8I3M9P4 A0A8I3MA93 A0A8I3MBK3 A0A8I3MC04 A0A8I3ME07 A0A8I3ME61 A0A8I3MGQ1 A0A8I3MHA7 A0A8I3MKF9 A0A8I3MM75 A0A8I3MM87 A0A8I3MN59 A0A8I3MNZ2 A0A8I3MPN0 A0A8I3MQK6 A0A8I3MQM8 A0A8I3MRI6 A0A8I3MRZ4 A0A8I3MRZ6 A0A8I3MS01 A0A8I3MU83 A0A8I3MVK0 A0A8I3MX13 A0A8I3MXL9 A0A8I3MXY0 A0A8I3MYE3 A0A8I3MYF9 A0A8I3N081 A0A8I3N0P5 A0A8I3N125 A0A8I3N207 A0A8I3N302 A0A8I3N349 A0A8I3N4S6 A0A8I3N4Y4 A0A8I3N5K9 A0A8I3N640 A0A8I3N6A0 A0A8I3N6I2 A0A8I3NAD1 A0A8I3NAS6 A0A8I3ND24 A0A8I3NDC4 A0A8I3NDU8 A0A8I3NDZ2 A0A8I3NEA4 A0A8I3NGZ9 A0A8I3NHT7 A0A8I3NHV8 A0A8I3NKU5 A0A8I3NLJ6 A0A8I3NMN5 A0A8I3NMV4 A0A8I3NNN1 A0A8I3NNT7 A0A8I3NPA7 A0A8I3NPM9 A0A8I3NPT8 A0A8I3NPW0 A0A8I3NQ26 A0A8I3NQA0 A0A8I3NQV1 A0A8I3NR19 A0A8I3NVC1 A0A8I3NWG9 A0A8I3NXJ3 A0A8I3NYI6 A0A8I3NZN3 A0A8I3P0A1 A0A8I3P108 A0A8I3P1U0 A0A8I3P2E9 A0A8I3P3I1 A0A8I3P4V6 A0A8I3P5Y8 A0A8I3P7L3 A0A8I3P831 A0A8I3P8G7 A0A8I3P9H6 A0A8I3PBD4 A0A8I3PBE4 A0A8I3PCM1 A0A8I3PDF9 A0A8I3PDW8 A0A8I3PE74 A0A8I3PEX2 A0A8I3PH14 A0A8I3PIK0 A0A8I3PIX9 A0A8I3PJF2 A0A8I3PJU6 A0A8I3PM36 A0A8I3PM57 A0A8I3PMD7 A0A8I3PNM4 A0A8I3PP20 A0A8I3PPP9 A0A8I3PPR9 A0A8I3PQY2 A0A8I3PRQ9 A0A8I3PS75 A0A8I3PV05 A0A8I3PVZ2 A0A8I3PWB5 A0A8I3PXC2 A0A8I3PXL4 A0A8I3PYB5 A0A8I3PZU6 A0A8I3Q0H0 A0A8I3Q0K2 A0A8I3Q2D1 A0A8I3Q2F2 A0A8I3Q2S6 A0A8I3Q4F7 A0A8I3Q7L4 A0A8I3Q7S8 A0A8I3Q8Q0 A0A8I3Q8T3 A0A8I3QE57 A0A8I3QV74 A0A8I3RPW6 A0A8I3RR88 A0A8I3RSE4 A0A8I3RSK6 A0A8I3RT67 A0A8I3RTH5 A0A8I3RTK9 A0A8I3RTX6 A0A8I3RUS6 A0A8I3RVM8 A0A8I3RW80 A0A8I3RWJ1 A0A8I3RWZ6 A0A8I3RXC1 A0A8I3RXP5 A0A8I3RYN2 A0A8I3RZ84 A0A8I3RZH5 A0A8I3S3R7 A0A8I3S583 A0A8I3S5G1 A0A8I3S5I1 A0A8I3S656 A0A8I3S6A4 A0A8I3S6V0 A0A8I3S7S8 A0A8I3S925 A0A8I3S929 A0A8I3SA57 A0A8I3SBF9 A0A8I3SBJ6 A0A8I3SCV7 A2SXS6 B9UM26 E2RKA3 E2RQ21 E2RTH0 O02813 O18914 O62729 O97564 P11616 P38400 P41324 P49670 P62872 P63210 P79147 P79250 Q28300 Q28309 Q2ABC7 Q2ABD0 Q2ABD1 Q2ABD4 Q2ABD5 Q2ABD6 Q2ABD8 Q2ABE0 Q49LX5 Q5ECR9 Q5KSV9 Q5XXR2 Q68A93 Q68AZ0 Q8MIP6 Q9BDQ4 Q9BDQ5	ADORA1 ADORA3 ADRA2A ADRA2B ADRA2C AGT AGTR2 ANXA1 APP BDKRB1 BDKRB2 Bdkrb2 C3 C3AR1 C5 C5AR1 CAFA-T2R43 CASR CB2 CCL19 CCL23 CCL25 CCL28 CCL4 CCR1 CCR10 CCR5 CCR7 CCR9 CHRM2 CHRM4 CMKBR5 CNR2 CX3CL1 CX3CR1 CXCL10 CXCL11 CXCL13 CXCL16 CXCL6 CXCL8 CXCR2 CXCR3 CXCR5 CXCR6 DRD3 FPR2 GABBR1 GABBR2 GAL GALR1 GALR2 GALR3 GNAI1 GNAI2 GNAI3 GNAT1 GNAT2 GNAT3 GNB1 GNB2 GNB3 GNB4 GNB5 GNG11 GNG13 GNG2 GNG3 GNG4 GNG8 GNGT1 GNGT2 GPER1 GPR17 GPR18 GPR183 GPR31 GPR37 GPR37L1 GPR55 GPSM1 GPSM2 GPSM3 GRM2 GRM3 GRM4 GRM6 GRM7 GRM8 HCAR1 HCAR2 HRH4 HTR1B HTR1D HTR1E HTR1F HTR5A IL8 KNG1 LOC100682759 LOC119863873 LPAR1 LPAR2 LPAR3 LPAR5 MCH MCHR1 MCHR2 MTNR1A MTNR1B NMS NMU NMUR1 NMUR2 NPB NPBWR1 NPY NPY1R NPY2R NPY4R NPY5 NPY5R OPN1LW OPN1SW OPN3 OPN5 OPRD1 OPRK1 OPRM1 OXER1 OXGR1 P2RY12 P2RY14 PCP2 PDYN PENK PMCH POMC PPBP PPY PSAP PTGDR2 PTGER3 PYY RCP RDC7 RGR RGS1 RGS11 RGS12 RGS13 RGS14 RGS16 RGS17 RGS18 RGS19 RGS20 RGS21 RGS3 RGS4 RGS5 RGS6 RGS7 RGS8 RGS9 RHO RLN3 RRH RXFP3 S1PR2 S1PR3 S1PR4 S1PR5 SCYA4 SRC SST SSTR1 SSTR2 SSTR3 SSTR5 SUCNR1 TAS1R1 TAS1R3 TAS2R1 TAS2R10 TAS2R3 TAS2R38 TAS2R39 TAS2R4 TAS2R40 TAS2R41 TAS2R42 TAS2R5 TAS2R7 ccr9 cx3cl1 gpr81	Canis familiaris (dog)
Serotonin receptors	5-hydroxytryptamine receptor 1A 5-hydroxytryptamine receptor 1B 5-hydroxytryptamine receptor 1D 5-hydroxytryptamine receptor 1E 5-hydroxytryptamine receptor 1F 5-hydroxytryptamine receptor 2A 5-hydroxytryptamine receptor 2B 5-hydroxytryptamine receptor 2C 5-hydroxytryptamine receptor 4 5-hydroxytryptamine receptor 5A 5-hydroxytryptamine receptor 7 G-protein coupled receptors family 1 profile domain-containing protein	A0A8I3MN28 A0A8I3N6U6 A0A8I3NAA7 A0A8I3NLJ6 A0A8I3NMV4 A0A8I3PC67 A0A8I3RXP5 A0A8I3S1Q6 A0A8I3S5I1 A0A8I3S709 O46635 P79250	5-HTR2A HTR1B HTR1D HTR1E HTR1F HTR2A HTR2B HTR2C HTR4 HTR5A HTR6 HTR7	Canis familiaris (dog)
Macroautophagy	5'-AMP-activated protein kinase catalytic subunit alpha-2 5'-AMP-activated protein kinase subunit beta-1 5'-AMP-activated protein kinase subunit gamma-1 Association with the SNF1 complex (ASC) domain-containing protein Autophagy and beclin 1 regulator 1 Autophagy protein 5 Autophagy related 13 Autophagy related 14 Autophagy related 16 like 1 Autophagy-related protein 101 Autophagy-related protein 9 Autophagy-related protein 9 Beclin-1 Charged multivesicular body protein 2B Charged multivesicular body protein 2a Charged multivesicular body protein 3 Charged multivesicular body protein 4A Charged multivesicular body protein 4B Charged multivesicular body protein 4C Charged multivesicular body protein 7 Cysteine protease ATG4D Cysteine protease Cysteine protease Cysteine protease Dynein light chain Dynein light chain GABA type A receptor associated protein like 2 Gamma-aminobutyric acid receptor-associated protein Late endosomal/lysosomal adaptor, MAPK and MTOR activator 2 Microtubule associated protein 1 light chain 3 gamma Myotubularin related protein 14 Neutral amino acid transporter 9 Phosphatidylinositol 3-kinase catalytic subunit type 3 Protein kinase AMP-activated non-catalytic subunit gamma 2 Protein kinase AMP-activated non-catalytic subunit gamma 3 RB1 inducible coiled-coil 1 Ragulator complex protein LAMTOR1 Ragulator complex protein LAMTOR3 Ragulator complex protein LAMTOR4 Ragulator complex protein LAMTOR5 Ras homolog, mTORC1 binding Ras-related GTP-binding protein Ras-related GTP-binding protein Ras-related GTP-binding protein Ras-related GTP-binding protein Regulatory associated protein of MTOR complex 1 Serine/threonine-protein kinase mTOR Serine/threonine-protein kinase TSC complex subunit 1 TSC complex subunit 2 Target of rapamycin complex subunit LST8 UV radiation resistance associated Ubiquitin-like modifier-activating enzyme ATG7 Ubiquitin-like protein ATG12 Ubiquitin-like-conjugating enzyme ATG10 Ubiquitin-like-conjugating enzyme ATG3 Uncharacterized protein WD repeat domain phosphoinositide-interacting protein 2 WD repeat domain phosphoinositide-interacting protein 3 WD repeat domain phosphoinositide-interacting protein 4 WD repeat domain, phosphoinositide interacting 1 non-specific serine/threonine protein kinase protein-tyrosine-phosphatase	A0A8I3MF29 A0A8I3MJG3 A0A8I3MPV7 A0A8I3MS83 A0A8I3MTF8 A0A8I3MUN9 A0A8I3MWD3 A0A8I3MX71 A0A8I3N241 A0A8I3N3R3 A0A8I3N683 A0A8I3N7J8 A0A8I3N8Z8 A0A8I3N9T9 A0A8I3NBC3 A0A8I3NDI3 A0A8I3NFM6 A0A8I3NIS5 A0A8I3NIZ5 A0A8I3NME4 A0A8I3NR33 A0A8I3NRH7 A0A8I3NTI1 A0A8I3NTN6 A0A8I3P1L5 A0A8I3P1V6 A0A8I3P1X3 A0A8I3P2D4 A0A8I3P766 A0A8I3PBL8 A0A8I3PFE0 A0A8I3PFM5 A0A8I3PK33 A0A8I3PLN8 A0A8I3PM06 A0A8I3PP92 A0A8I3PPE0 A0A8I3PS98 A0A8I3PT36 A0A8I3PTC5 A0A8I3PWP1 A0A8I3PY75 A0A8I3PYA9 A0A8I3PZS6 A0A8I3Q041 A0A8I3Q098 A0A8I3Q0F1 A0A8I3Q4C7 A0A8I3QAP4 A0A8I3QCJ3 A0A8I3QFN1 A0A8I3QXU8 A0A8I3QZ96 A0A8I3RS87 A0A8I3RU83 A0A8I3RW45 A0A8I3RWY6 A0A8I3RXW5 A0A8I3S4R4 A0A8I3S4Z7 A0A8I3S6E7 A0A8I3SA74 E2RDP2	AMBRA1 ATG10 ATG101 ATG12 ATG13 ATG14 ATG16L1 ATG3 ATG4A ATG4B ATG4C ATG4D ATG5 ATG7 ATG9A ATG9B BECN1 CHMP2A CHMP2B CHMP3 CHMP4A CHMP4B CHMP4C CHMP7 DYNLL1 DYNLL2 GABARAP GABARAPL2 LAMTOR1 LAMTOR2 LAMTOR3 LAMTOR4 LAMTOR5 MAP1LC3C MLST8 MTMR14 MTMR3 MTOR PIK3C3 PIK3R4 PRKAA2 PRKAB1 PRKAB2 PRKAG1 PRKAG2 PRKAG3 RB1CC1 RHEB RPTOR RRAGA RRAGB RRAGC RRAGD SLC38A9 TSC1 TSC2 ULK1 UVRAG WDR45 WDR45B WIPI1 WIPI2	Canis familiaris (dog)
Keratinization	4Fe-4S ferredoxin-type domain-containing protein Desmocollin 1 Desmoglein 1 Desmoglein 2 Desmoglein 3 Desmoglein 4 Desmoglein-3 Desmoplakin IF rod domain-containing protein Junction plakoglobin Keratin 12 Keratin 18 Keratin 23 Keratin 24 Keratin 26 Keratin 28 Keratin 32 Keratin 33B Keratin 35 Keratin 36 Keratin 39 Keratin 3 Keratin 40 Keratin 72 Keratin 73 Keratin 74 Keratin 75 Keratin 76 Keratin 77 Keratin 78 Keratin 80 Keratin 82 Keratin 84 Keratin 85 Keratin 9 Keratin associated protein 8-1 Keratin, type I cytoskeletal 10 Keratin, type I cytoskeletal 10 Keratin, type I cytoskeletal 19 Keratin, type I cytoskeletal 20 Keratin, type I cytoskeletal 25 Keratin, type I cytoskeletal 27 Keratin, type II cytoskeletal 8 Keratin-associated protein 12-1-like Keratin-associated protein 9-3-like Keratin-associated protein Keratin-associated protein Keratin-associated protein Keratin-associated protein Plakophilin 1 Plakophilin 2 Plakophilin 3 Plakophilin 4 Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein	A0A5F4CC19 A0A5F4CZ72 A0A8I3MUF8 A0A8I3MVK7 A0A8I3N105 A0A8I3N1J2 A0A8I3N5G6 A0A8I3NBY4 A0A8I3NCT2 A0A8I3NDC0 A0A8I3NEH7 A0A8I3NF36 A0A8I3NF93 A0A8I3NHU5 A0A8I3NIB1 A0A8I3NJG7 A0A8I3NJK2 A0A8I3NKA1 A0A8I3NKS4 A0A8I3NL10 A0A8I3NL87 A0A8I3NMX6 A0A8I3NNI9 A0A8I3NNW0 A0A8I3NPY5 A0A8I3NQB8 A0A8I3NQV4 A0A8I3NQY7 A0A8I3NS58 A0A8I3NSM8 A0A8I3NVV6 A0A8I3NXE8 A0A8I3NYA0 A0A8I3NZ03 A0A8I3P212 A0A8I3P7T0 A0A8I3P9A1 A0A8I3PD35 A0A8I3PD89 A0A8I3PEZ2 A0A8I3PG96 A0A8I3PJ84 A0A8I3PK78 A0A8I3PMV1 A0A8I3PPU4 A0A8I3PTF9 A0A8I3PUR6 A0A8I3PWA5 A0A8I3PWP6 A0A8I3PXA2 A0A8I3PYF6 A0A8I3Q1A4 A0A8I3Q1G9 A0A8I3Q2T7 A0A8I3QMH2 A0A8I3RW47 A0A8I3RXM1 A0A8I3RY38 A0A8I3RZQ2 A0A8I3S024 A0A8I3S0K7 A0A8I3S5Q3 A0A8I3S7M3 A0A8I3S850 A0A8I3S8A6 Q6EIZ0 Q7YRU7	DSC1 DSC3 DSG1 DSG2 DSG3 DSG4 DSP JUP KER10 KRT10 KRT12 KRT15 KRT18 KRT20 KRT23 KRT24 KRT25 KRT26 KRT27 KRT28 KRT3 KRT31 KRT32 KRT33B KRT34 KRT35 KRT36 KRT37 KRT38 KRT39 KRT40 KRT41 KRT72 KRT73 KRT74 KRT75 KRT76 KRT77 KRT78 KRT80 KRT81 KRT82 KRT83 KRT84 KRT85 KRT9 KRTAP11-1 KRTAP24-1 KRTAP3-1 KRTAP8-1 LOC100685322 LOC100685403 LOC100686265 LOC100686358 LOC102151268 LOC102151404 LOC102151604 LOC102151831 LOC102157302 LOC119873184 LOC610887 PKP1 PKP2 PKP3 PKP4	Canis familiaris (dog)
Lewis blood group biosynthesis	4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase 9 Alpha-(1,3)-fucosyltransferase Alpha-(1,3)-fucosyltransferase Beta-1,3-galactosyltransferase 4 Beta-1,4-N-acetyl-galactosaminyltransferase 2 Fucosyltransferase Fucosyltransferase Fucosyltransferase Hexosyltransferase Hexosyltransferase L-Fucosyltransferase ST3 beta-galactoside alpha-2,3-sialyltransferase 3 ST3 beta-galactoside alpha-2,3-sialyltransferase 4 ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 6 Type 2 lactosamine alpha-2,3-sialyltransferase	A0A8I3MCT3 A0A8I3NB27 A0A8I3NB67 A0A8I3NFY5 A0A8I3NLH2 A0A8I3NR40 A0A8I3NRD0 A0A8I3P0Y9 A0A8I3PNT8 A0A8I3PQF7 A0A8I3Q8H7 A0A8I3RVW4 A0A8I3S1H8 Q5TJE8 Q659L1	B3GALT2 B3GALT4 B3GALT5 B4GALNT2 FUT10 FUT11 FUT2 FUT4 FUT5 FUT7 FUT9 ST3GAL3 ST3GAL4 ST3GAL6 ST6GALNAC6	Canis familiaris (dog)	G39211DH G81971FM G83633HB G90387AM G98173LG
Vitamin B5 (pantothenate) metabolism	4'-phosphopantetheine phosphatase Fatty acid synthase L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase Mitochondrial coenzyme A transporter SLC25A42 PDZ domain-containing protein 11 Pantetheinase Solute carrier family 25 member 16 Solute carrier family 5 member 6	A0A8I3MUX5 A0A8I3MVX3 A0A8I3MY61 A0A8I3PCZ1 A0A8I3Q2U7 A0A8I3RQN4 A0A8I3S3J2 Q9TSX8	AASDHPPT FASN PANK4 PDZD11 SLC25A16 SLC25A42 SLC5A6 VNN1	Canis familiaris (dog)
GPVI-mediated activation cascade	3-phosphoinositide-dependent protein kinase 1 C-type lectin domain-containing protein Cell division control protein 42 homolog High affinity immunoglobulin epsilon receptor subunit gamma Lymphocyte cytosolic protein 2 Megakaryocyte and platelet inhibitory receptor G6b Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphoinositide 3-kinase regulatory subunit 5 Phosphoinositide phospholipase C Phosphoinositide-3-kinase regulatory subunit 2 Phosphoinositide-3-kinase regulatory subunit 3 Phosphoinositide-3-kinase regulatory subunit 6 Podoplanin Rac family small GTPase 2 Ras homolog family member B Ras homolog family member G Ras-related C3 botulinum toxin substrate 1 Ras-related C3 botulinum toxin substrate 1 Transforming protein RhoA Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein phosphatase non-receptor type Tyrosine-protein phosphatase non-receptor type Uncharacterized protein Uncharacterized protein Vav guanine nucleotide exchange factor 1 Vav guanine nucleotide exchange factor 2 Vav guanine nucleotide exchange factor 3 phosphatidylinositol-4,5-bisphosphate 3-kinase phosphatidylinositol-4,5-bisphosphate 3-kinase phosphatidylinositol-4,5-bisphosphate 3-kinase	A0A5F4C2B1 A0A8I3MGV8 A0A8I3MHV4 A0A8I3MMK3 A0A8I3MQX7 A0A8I3MY22 A0A8I3N060 A0A8I3N5M3 A0A8I3N971 A0A8I3NA65 A0A8I3NAC6 A0A8I3NC73 A0A8I3NEZ8 A0A8I3NH46 A0A8I3NHC2 A0A8I3NIT3 A0A8I3NZG2 A0A8I3P075 A0A8I3P3G0 A0A8I3P3X1 A0A8I3P519 A0A8I3PMT9 A0A8I3PUN0 A0A8I3PVV6 A0A8I3PWC6 A0A8I3PWT3 A0A8I3PY16 A0A8I3QSK6 A0A8I3S3N2 A0A8I3S601 P60952 P62999 Q95152	CDC42 CLEC1B FCER1G FYN GP40 GP6 LAT LCK LCP2 LOC100856339 LYN MPIG6B PDPK1 PDPN PIK3CA PIK3CB PIK3CG PIK3R1 PIK3R2 PIK3R5 PIK3R6 PLCG2 PTPN11 PTPN6 RAC1 RAC2 RHOA RHOB RHOG SYK VAV1 VAV2 VAV3	Canis familiaris (dog)
PI3K/AKT Signaling	3-phosphoinositide-dependent protein kinase 1 B7-1 protein CD19 molecule CD86 molecule EGF-like domain-containing protein Epiregulin Estrogen receptor beta Estrogen receptor Fibroblast growth factor 23 Fibroblast growth factor 5 Fibroblast growth factor 7 Fibroblast growth factor receptor 3 Fibroblast growth factor receptor 4 Fibroblast growth factor receptor substrate 2 Fibroblast growth factor receptor Fibroblast growth factor receptor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fms related receptor tyrosine kinase 3 ligand GRB2 associated binding protein 1 GRB2 associated binding protein 2 Growth factor receptor bound protein 2 Hepatocyte growth factor receptor Hepatocyte growth factor Inducible T-cell costimulator Insulin receptor substrate 1 Insulin receptor substrate 2 Interleukin 1 receptor accessory protein Interleukin-1 receptor-associated kinase 4 Interleukin-33 Kit ligand Klotho beta Klotho Mast/stem cell growth factor receptor Kit Multifunctional fusion protein Myeloid differentiation primary response protein MyD88 Neuregulin 2 Neuregulin 3 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphoinositide-3-kinase adaptor protein 1 Phosphoinositide-3-kinase regulatory subunit 2 Phosphoinositide-3-kinase regulatory subunit 3 Platelet-derived growth factor receptor alpha Platelet-derived growth factor receptor beta Platelet-derived growth factor subunit A Platelet-derived growth factor subunit B Pro-epidermal growth factor Pro-neuregulin-1, membrane-bound isoform Proheparin-binding EGF-like growth factor Proline rich 5 RPTOR independent companion of MTOR complex 2 Rac family small GTPase 2 Ras homolog family member G Ras-related C3 botulinum toxin substrate 1 Ras-related C3 botulinum toxin substrate 1 Receptor protein-tyrosine kinase Receptor protein-tyrosine kinase Receptor protein-tyrosine kinase Receptor protein-tyrosine kinase Serine/threonine-protein kinase Sgk1 Serine/threonine-protein kinase mTOR Striatin T cell receptor associated transmembrane adaptor 1 T-cell-specific surface glycoprotein CD28 TNF receptor-associated factor 6 Target of rapamycin complex 2 subunit MAPKAP1 Target of rapamycin complex subunit LST8 Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein phosphatase non-receptor type Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Vav guanine nucleotide exchange factor 1 non-specific serine/threonine protein kinase phosphatidylinositol-4,5-bisphosphate 3-kinase phosphatidylinositol-4,5-bisphosphate 3-kinase phosphatidylinositol-4,5-bisphosphate 3-kinase receptor protein-tyrosine kinase	A0A0B4J199 A0A5F4C2B1 A0A7U3JWB8 A0A8I3MAV6 A0A8I3MIK8 A0A8I3MJG3 A0A8I3MN72 A0A8I3MP09 A0A8I3MPF4 A0A8I3MQX7 A0A8I3MRL6 A0A8I3MT80 A0A8I3MX71 A0A8I3MZ71 A0A8I3MZG1 A0A8I3N0H9 A0A8I3N488 A0A8I3N5M3 A0A8I3N8T5 A0A8I3N971 A0A8I3N9M7 A0A8I3NA65 A0A8I3NAC6 A0A8I3NAN8 A0A8I3NEF4 A0A8I3NFQ7 A0A8I3NGY1 A0A8I3NH46 A0A8I3NHA2 A0A8I3NHF3 A0A8I3NIT3 A0A8I3NKX5 A0A8I3NLT7 A0A8I3NNZ2 A0A8I3NS74 A0A8I3NSU7 A0A8I3NTD6 A0A8I3NV07 A0A8I3NVK5 A0A8I3NVV1 A0A8I3NVW9 A0A8I3NWK3 A0A8I3NXI8 A0A8I3NYK3 A0A8I3P2V4 A0A8I3P3M1 A0A8I3P3X1 A0A8I3P4L9 A0A8I3P519 A0A8I3P6D2 A0A8I3PJY6 A0A8I3PK39 A0A8I3PKX6 A0A8I3PMT9 A0A8I3PN81 A0A8I3PR42 A0A8I3PT69 A0A8I3PV99 A0A8I3PWT3 A0A8I3Q059 A0A8I3Q1C3 A0A8I3Q209 A0A8I3Q314 A0A8I3Q525 A0A8I3Q5L9 A0A8I3RPS3 A0A8I3RR99 A0A8I3RRT3 A0A8I3RSF1 A0A8I3RTN7 A0A8I3RYJ5 A0A8I3S0I1 A0A8I3S0T0 A0A8I3S333 A0A8I3S3N2 A0A8I3S8G3 A0A8I3SAY5 A0A8I3SBF9 E2REX2 J9P0B3 J9P3I7 J9P8K0 O97799 O97863 P62999 P79150 Q06220 Q20FD0 Q6Q7I7 Q7YR73 Q867B7 Q9TQX1	AILIM AREG BTC CD19 CD28 CD80 CD86 EGF EGFR EPGN ERBB2 ERBB3 ERBB4 EREG ESR1 ESR2 FGF1 FGF10 FGF16 FGF17 FGF18 FGF19 FGF20 FGF22 FGF23 FGF3 FGF3A FGF4 FGF4B FGF4C FGF5 FGF6 FGF7 FGF7A FGF7B FGF8 FGF8B FGF9 FGFR1 FGFR2 FGFR3 FGFR4 FLT3 FLT3LG FRS2 FYN GAB1 GAB2 GRB2 HBEGF HGF ICOS IL1RAP IL33 IRAK1 IRAK4 IRS1 IRS2 KGF KIT KITLG KL KLB LCK LOC100856339 MAPKAP1 MET MGF MLST8 MTOR MYD88 NRG1 NRG2 NRG3 PDGFA PDGFB PDGFRA PDGFRB PDPK1 PIK3AP1 PIK3CA PIK3CB PIK3CD PIK3R1 PIK3R2 PRR5 PTPN11 RAC1 RAC2 RHOG RICTOR SGK1 SRC STRN TGFA TRAF6 TRAT1 VAV1	Canis familiaris (dog)
Integrin signaling	3-phosphoinositide-dependent protein kinase 1 Amyloid beta A4 precursor protein-binding family B member 1-interacting protein Fibronectin Focal adhesion kinase 1 Integrin beta Integrin subunit alpha 2b RAS guanyl releasing protein 2 RAS guanyl-releasing protein 1 Rap guanine nucleotide exchange factor 3 Rap guanine nucleotide exchange factor 4 SHC-transforming protein 1 Talin 1 Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein phosphatase non-receptor type small monomeric GTPase small monomeric GTPase von Willebrand factor von Willebrand factor	A0A8I3MQX7 A0A8I3N6K0 A0A8I3N737 A0A8I3NMY1 A0A8I3NUL4 A0A8I3NUU1 A0A8I3P3G0 A0A8I3P4Z0 A0A8I3PED8 A0A8I3PMU9 A0A8I3PW63 A0A8I3PWD7 A0A8I3PXV2 A0A8I3PZ28 A0A8I3Q868 A0A8I3RUF3 A0A8I3RVR5 A0A8I3SBF9 A0A8I3SCK0 Q28295	APBB1IP CSK F8VWF FN1 ITGA2B ITGB3 PDPK1 PTK2 PTPN1 RAP1A RAP1B RAPGEF3 RAPGEF4 RASGRP1 RASGRP2 SHC1 SRC SYK TLN1 VWF	Canis familiaris (dog)
Sphingolipid de novo biosynthesis	3-dehydrosphinganine reductase Broad substrate specificity ATP-binding cassette transporter ABCG2 Ceramide synthase 1 Ceramide synthase 2 Ceramide synthase 3 Ceramide synthase 4 Ceramide synthase 5 Ceramide synthase 6 Cytochrome b5 heme-binding domain-containing protein Delta 4-desaturase, sphingolipid 2 Fatty acid 2-hydroxylase Major facilitator superfamily domain containing 2B Multidrug resistance-associated protein 1 Multidrug resistance-associated protein 1 ORM1-like protein ORM1-like protein ORM1-like protein SPNS lysolipid transporter 2, sphingosine-1-phosphate Serine palmitoyltransferase 1 Serine palmitoyltransferase long chain base subunit 2 Serine palmitoyltransferase long chain base subunit 3 Sphingolipid delta(4)-desaturase DES1 Sphingomyelin synthase 2 Sphingosine kinase 1 Sphingosine kinase 2 Sterile alpha motif domain containing 8 Uncharacterized protein Uncharacterized protein	A0A8I3MDB1 A0A8I3MDX2 A0A8I3MH69 A0A8I3MTG4 A0A8I3MVV0 A0A8I3MZT5 A0A8I3N0C8 A0A8I3N1I8 A0A8I3N6A8 A0A8I3N8H8 A0A8I3NCL9 A0A8I3NE51 A0A8I3NF48 A0A8I3P1Y0 A0A8I3P1Z6 A0A8I3P4B7 A0A8I3PAM7 A0A8I3PG24 A0A8I3PM33 A0A8I3PMG7 A0A8I3PQ53 A0A8I3Q2P7 A0A8I3S0D0 A0A8I3S194 A0A8I3S6X3 A0A8I3S790 B3RFJ1 Q6UR05	ABCC1 ABCG2 Abcg2 CERS1 CERS2 CERS3 CERS4 CERS5 CERS6 CYB5B DEGS1 DEGS2 FA2H KDSR MFSD2B MRP1 ORMDL1 ORMDL2 ORMDL3 SAMD8 SGMS1 SGMS2 SPHK1 SPHK2 SPNS2 SPTLC1 SPTLC2 SPTLC3 SPTSSA	Canis familiaris (dog)

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