GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **176 - 200** of **268** in total

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Pathway Name ▲	Protein Name	UniProt ID	Gene Symbol	Organism	GlyTouCan ID
Phospholipase C-mediated cascade; FGFR2	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma Fibroblast growth factor 23 Fibroblast growth factor 5 Fibroblast growth factor 7 Fibroblast growth factor receptor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Multifunctional fusion protein Uncharacterized protein	A0A0B4J199 A0A7U3JWB8 A0A8I3MIK8 A0A8I3MP09 A0A8I3NHF3 A0A8I3NSU7 A0A8I3NTD6 A0A8I3NV07 A0A8I3NYK3 A0A8I3P6D2 A0A8I3PJY6 A0A8I3SAY5 A0A8I3SCI7 E2REX2 J9P0B3 J9P3I7 J9P8K0 P79150 Q20FD0	FGF1 FGF10 FGF16 FGF17 FGF18 FGF20 FGF22 FGF23 FGF3 FGF3A FGF4 FGF4B FGF4C FGF5 FGF6 FGF7 FGF7A FGF7B FGF8 FGF8B FGF9 FGFR2 KGF PLCG1	Canis familiaris (dog)
Phospholipase C-mediated cascade; FGFR3	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma Fibroblast growth factor 23 Fibroblast growth factor 5 Fibroblast growth factor receptor 3 Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Multifunctional fusion protein Uncharacterized protein	A0A0B4J199 A0A7U3JWB8 A0A8I3MIK8 A0A8I3NHF3 A0A8I3NS74 A0A8I3NTD6 A0A8I3NV07 A0A8I3PJY6 A0A8I3SAY5 A0A8I3SCI7 J9P0B3 J9P3I7 J9P8K0 Q20FD0	FGF1 FGF16 FGF17 FGF18 FGF20 FGF23 FGF3A FGF4 FGF4B FGF4C FGF5 FGF7A FGF8 FGF8B FGF9 FGFR3 PLCG1	Canis familiaris (dog)
Phosphorylation of CD3 and TCR zeta chains	Ig-like domain-containing protein Immunoglobulin V-set domain-containing protein MHC class II DR alpha chain Major histocompatibility complex, class II, DQ alpha 1 Major histocompatibility complex, class II, DQ beta 2 Phosphoprotein membrane anchor with glycosphingolipid microdomains 1 T cell receptor alpha variable 29/delta variable 5 T-cell surface glycoprotein CD3 delta chain T-cell surface glycoprotein CD3 epsilon chain T-cell surface glycoprotein CD3 gamma chain T-cell surface glycoprotein CD3 zeta chain T-cell surface glycoprotein CD4 Tyrosine-protein kinase Tyrosine-protein kinase Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein protein-tyrosine-phosphatase protein-tyrosine-phosphatase protein-tyrosine-phosphatase	A0A8I3MED5 A0A8I3MFY1 A0A8I3MJ11 A0A8I3MKK6 A0A8I3MV98 A0A8I3MZ69 A0A8I3NAC6 A0A8I3NTK0 A0A8I3NYA3 A0A8I3P4A1 A0A8I3P4Z0 A0A8I3P564 A0A8I3P598 A0A8I3PAB8 A0A8I3PC26 A0A8I3PV90 A0A8I3S023 A0A8I3S2N1 A0A8I3S3J5 P27597 P33705	CD247 CD3D CD3E CD3G CD4 CSK DLA-DQA1 DLA-DRA HLA-DQB2 LCK PAG1 PTPN22 PTPRC PTPRJ TRAV29DV5	Canis familiaris (dog)
Platelet Adhesion to exposed collagen	ADAM metallopeptidase with thrombospondin type 1 motif 13 High affinity immunoglobulin epsilon receptor subunit gamma Tyrosine-protein kinase Tyrosine-protein kinase Uncharacterized protein von Willebrand factor von Willebrand factor	A0A8I3N060 A0A8I3NAX6 A0A8I3P3X1 A0A8I3PUN0 A0A8I3QSK6 A0A8I3SCK0 Q28295	ADAMTS13 F8VWF FCER1G FYN GP6 LYN VWF	Canis familiaris (dog)
Platelet degranulation	ATP binding cassette subfamily C member 4 Actin gamma 1 Actin, cytoplasmic 2 Actinin alpha 2 Actinin alpha 4 Albumin Alpha 1 antitrypsin Alpha-1-B glycoprotein Alpha-1-acid glycoprotein Alpha-2-HS-glycoprotein Alpha-2-macroglobulin Alpha-actinin-1 Amyloid beta precursor like protein 2 Amyloid-beta A4 protein Annexin Apolipoprotein A-I Beta-2-glycoprotein 1 Bromodomain and PHD finger containing 3 CD109 molecule CYFIP related Rac1 interactor B Cathepsin W Chitinase domain-containing protein 1 Clusterin Coagulation factor V Coagulation factor XIII A chain Complement factor D EF-hand domain-containing protein Endonuclease domain containing 1 Extracellular matrix protein 1 FERM domain containing kindlin 3 Fibronectin Fructose-bisphosphate aldolase GTP binding protein 2 Galectin-3-binding protein Growth arrest specific 6 Hepatocyte growth factor Histidine-rich glycoprotein Hsp90 co-chaperone Cdc37-like 1 Hyaluronan binding protein 4 Immunoglobulin superfamily containing leucine rich repeat Insulin-like growth factor I Insulin-like growth factor II Integrin beta Integrin subunit alpha 2b Inter-alpha-trypsin inhibitor heavy chain 4 Inter-alpha-trypsin inhibitor heavy chain H3 Kininogen 1 LHFPL tetraspan subfamily member 2 Left-right determination factor Lymphocyte antigen 6 family member G6F Lysosomal associated membrane protein 2 MICOS complex subunit Mesencephalic astrocyte derived neurotrophic factor Metalloproteinase inhibitor 1 Metalloproteinase inhibitor 3 NADH-cytochrome b5 reductase NHL repeat containing 2 Obg-like ATPase 1 Phosphatase and actin regulator Plasminogen activator inhibitor 1 Plasminogen Platelet and endothelial cell adhesion molecule 1 Platelet glycoprotein 4 Platelet-derived growth factor (PDGF) family profile domain-containing protein Platelet-derived growth factor subunit A Platelet-derived growth factor subunit B Pleckstrin Prenylcysteine oxidase 1 like Pro-epidermal growth factor Pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) Prosaposin Protein FAM3C Protocadherin 7 Retinoic acid receptor responder protein 2 SPARC Saccharopine dehydrogenase-like oxidoreductase Secreted phosphoprotein 24 Secretogranin-3 Selectin P Selenoprotein P Serglycin Serpin family A member 3 Serpin family A member 4 Serpin family F member 2 Serpin family G member 1 Sulfhydryl oxidase Superoxide dismutase [Cu-Zn] Synaptotagmin like 4 Syntaxin-binding protein 2 TGF-beta family profile domain-containing protein Talin 1 Testis expressed 264, ER-phagy receptor Tetraspanin Tetraspanin Thrombospondin 1 Thymosin beta Transforming growth factor beta-3 proprotein Transforming growth factor beta Transforming growth factor beta Transgelin Tubulin alpha chain Uncharacterized protein Uncharacterized protein Vascular endothelial growth factor C Vascular endothelial growth factor D Vascular permeability factor Vinculin Vitamin K-dependent protein S WD repeat domain 1 protein disulfide-isomerase t-SNARE coiled-coil homology domain-containing protein von Willebrand factor von Willebrand factor	A0A0F7RNT6 A0A5F4D8V4 A0A8I3MDS4 A0A8I3MET0 A0A8I3MF27 A0A8I3MFB3 A0A8I3MIF9 A0A8I3MJD4 A0A8I3MJP4 A0A8I3MJV1 A0A8I3MLH1 A0A8I3MN98 A0A8I3MQM2 A0A8I3MQM8 A0A8I3MSG4 A0A8I3MSQ7 A0A8I3MWF4 A0A8I3MY68 A0A8I3MZY7 A0A8I3N024 A0A8I3N083 A0A8I3N1P4 A0A8I3N1U1 A0A8I3N2E8 A0A8I3N2K8 A0A8I3N3Q6 A0A8I3N493 A0A8I3N6K0 A0A8I3N7J4 A0A8I3N7S1 A0A8I3N9N1 A0A8I3NBJ3 A0A8I3ND38 A0A8I3NDE6 A0A8I3NDZ2 A0A8I3NE73 A0A8I3NEF4 A0A8I3NGI3 A0A8I3NI15 A0A8I3NIC8 A0A8I3NLI1 A0A8I3NMA5 A0A8I3NME3 A0A8I3NN14 A0A8I3NT28 A0A8I3NT63 A0A8I3NTB5 A0A8I3NV71 A0A8I3NX84 A0A8I3NZD4 A0A8I3P0H8 A0A8I3P3Z6 A0A8I3P5H2 A0A8I3P5J8 A0A8I3P5P0 A0A8I3P9H6 A0A8I3PCH7 A0A8I3PED8 A0A8I3PET9 A0A8I3PFD7 A0A8I3PIK8 A0A8I3PJ66 A0A8I3PM36 A0A8I3PMB5 A0A8I3PMU9 A0A8I3PPU8 A0A8I3PQB4 A0A8I3PQP6 A0A8I3PQY3 A0A8I3PSD1 A0A8I3PUZ4 A0A8I3PZZ6 A0A8I3Q1H9 A0A8I3Q1K1 A0A8I3Q1S9 A0A8I3Q4A4 A0A8I3Q4H4 A0A8I3Q4P5 A0A8I3Q5H9 A0A8I3Q5L9 A0A8I3Q5W3 A0A8I3Q7Y3 A0A8I3Q895 A0A8I3QAV8 A0A8I3QNS0 A0A8I3QUR2 A0A8I3RPA5 A0A8I3RQK1 A0A8I3RQL9 A0A8I3RSP7 A0A8I3RT50 A0A8I3RTY1 A0A8I3RUX2 A0A8I3RVR5 A0A8I3S1P1 A0A8I3S1V7 A0A8I3S1X8 A0A8I3S309 A0A8I3S396 A0A8I3S7S1 A0A8I3SCC7 A0A8I3SCD6 A0A8I3SCK0 A0A8I3SCT4 A1ILJ0 B8K1W7 P25473 P33703 P33712 Q28295 Q6Q308 Q6Q7I7 Q867B7	A1BG A2M ABCC4 ACTG1 ACTN1 ACTN2 AHSG ALB ALDOA ANXA5 APLP2 APOA1 APOH APOOL APP Abcc4 B9D2 BRPF3 CALM2 CANT1 CD109 CD36 CD63 CD9 CDC37L1 CFD CHID1 CLU CTSW CYB5R1 CYRIB ECM1 EGF ENDOD1 F13A1 F5 F8VWF FAM3C FERMT3 FLNA FN1 GAS6 GTPBP2 HABP4 HGF HRG IGF1 IGF2 IGFIA ISLR ITGA2B ITGB3 ITIH3 ITIH4 KNG1 LAMP2 LEFTY1 LGALS7B LHFPL2 LOC100685620 LOC102152706 LOC119866770 LOC490387 LY6G6F MAGED2 MANF NHLRC2 OLA1 PCDH7 PCYOX1L PDGFA PDGFB PECAM1 PHACTR2 PLEK PLG PPBP PROS1 PSAP QSOX1 RARRES2 SCCPDH SCG3 SELENOP SELP SERPINA1 SERPINA3 SERPINA4 SERPINE1 SERPINF2 SERPING1 SOD1 SPARC SPP2 SRGN STXBP2 SYTL4 TAGLN2 TEX264 TGFB2 TGFB3 THBS1 TIMP1 TIMP3 TLN1 TMX3 TUBA4A VCL VEGFA VEGFB VEGFC VEGFD VWF WDR1	Canis familiaris (dog)
Platelet homeostasis	P2X purinoceptor P2X purinoceptor P2X purinoceptor P2X purinoceptor P2X purinoceptor P2X purinoceptor P2X purinoceptor Platelet-activating factor acetylhydrolase	A0A8I3NPN3 A0A8I3NX68 A0A8I3P313 A0A8I3PPB8 A0A8I3PV78 A0A8I3Q0A9 A0A8I3QCF1 A0A8I3S3K0	P2RX1 P2RX2 P2RX3 P2RX4 P2RX5 P2RX6 P2RX7 PAFAH2	Canis familiaris (dog)
Post-translational modification: synthesis of GPI-anchored proteins	ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase Alkaline phosphatase Alkaline phosphatase CAMPATH-1 antigen CD109 molecule CEA cell adhesion molecule 1 CEA cell adhesion molecule 20 Carboxypeptidase M Contactin-5 Glycoprotein 2 Hemicentin 2 IZUMO1 receptor, JUNO Ig-like domain-containing protein LY6/PLAUR domain containing 1 LY6/PLAUR domain containing 3 LY6/PLAUR domain containing 4 LY6/PLAUR domain containing 5 LY6/PLAUR domain containing 6B Limbic system associated membrane protein Low affinity immunoglobulin gamma Fc region receptor III-A Low affinity immunoglobulin gamma Fc region receptor III-A Lymphocyte antigen 6 family member G6C Lymphocyte antigen 6 family member G6D Melanotransferrin NAD(P)(+)--arginine ADP-ribosyltransferase NAD(P)(+)--arginine ADP-ribosyltransferase Neuritin 1 like Neuritin 1 Neuronal growth regulator 1 Neurotrimin Opioid binding protein/cell adhesion molecule like Otoancorin Pantetheinase Peptidase S1 domain-containing protein Phosphatidylinositol-glycan-specific phospholipase D Placenta-expressed transcript 1 protein Prion like protein doppel Prostate stem cell antigen Reticulon 4 receptor like 1 Reticulon 4 receptor like 2 Retinoic acid early-inducible protein 1 domain-containing protein Reversion inducing cysteine rich protein with kazal motifs Shadow of prion protein Sperm acrosome associated 4 Tectorin alpha Tectorin beta Testis expressed 101 Thy-1 membrane glycoprotein UPAR/Ly6 domain-containing protein UPAR/Ly6 domain-containing protein UPAR/Ly6 domain-containing protein UPAR/Ly6 domain-containing protein UPAR/Ly6 domain-containing protein Uncharacterized protein Uncharacterized protein X-prolyl aminopeptidase 2	A0A5F4D8V4 A0A8I3MAT6 A0A8I3MB16 A0A8I3MC73 A0A8I3MEX4 A0A8I3MFF6 A0A8I3MGB5 A0A8I3MHK2 A0A8I3MI32 A0A8I3MK32 A0A8I3MP74 A0A8I3MTL7 A0A8I3MTQ6 A0A8I3MTU9 A0A8I3MZC0 A0A8I3N367 A0A8I3N3V2 A0A8I3N6F5 A0A8I3NAY9 A0A8I3NFT9 A0A8I3NGU2 A0A8I3NH91 A0A8I3NIQ2 A0A8I3NJB5 A0A8I3NMI6 A0A8I3NNX5 A0A8I3NQP0 A0A8I3NTH0 A0A8I3NZ50 A0A8I3P0V6 A0A8I3P2N1 A0A8I3P2X9 A0A8I3P9X8 A0A8I3PBG0 A0A8I3PFN4 A0A8I3PK10 A0A8I3PNW6 A0A8I3PYZ3 A0A8I3Q1D0 A0A8I3Q7C6 A0A8I3Q8E3 A0A8I3QHH1 A0A8I3QN81 A0A8I3RRI7 A0A8I3RUJ8 A0A8I3RVF3 A0A8I3RW46 A0A8I3RXK7 A0A8I3RXW9 A0A8I3RYC5 A0A8I3RYX0 A0A8I3S2E0 A0A8I3S779 E2RP87 Q28896 Q9TSX8	ALPI ALPL ART3 ART4 BST1 CD109 CD52 CDW52 CE5 CEACAM1 CEACAM20 CNTN5 CPM FCGR3A GLIPR2 GP2 GPIHBP1 GPLD1 HMCN2 IZUMO1R LOC100683099 LOC119875695 LOC476816 LOC478984 LSAMP LY6D LY6E LY6G6C LY6G6D LY6H LYPD1 LYPD3 LYPD4 LYPD5 LYPD6B LYPD8 MELTF NEGR1 NRN1 NRN1L NTM OPCML OTOA PLET1 PRND PSCA RTN4RL1 RTN4RL2 SPACA4 SPRN TECTA TECTB TEX101 THY1 VNN1 XPNPEP2	Canis familiaris (dog)
Post-translational protein phosphorylation	Albumin Alpha 1 antitrypsin Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase A Alpha-2-HS-glycoprotein Alpha-L-fucosidase Alpha-fetoprotein Ameloblastin Amelogenin X isoform Amelotin Amyloid beta precursor like protein 2 Amyloid-beta A4 protein Anoctamin Antithrombin-III Apolipoprotein A-I Apolipoprotein A-II Apolipoprotein A-V Apolipoprotein B Apolipoprotein E Apolipoprotein L3 Apolipoprotein L3 BPI fold containing family B member 2 Bone morphogenetic protein 4 C4a anaphylatoxin CCN family member 1 Cadherin-2 Calumenin Chordin like 1 Coagulation factor V Complement C3 Cytoskeleton associated protein 4 Dentin matrix acidic phosphoprotein 1 Disintegrin and metalloproteinase domain-containing protein 10 DnaJ homolog subfamily C member 3 Enamelin Endoplasmin FAM20 C-terminal domain-containing protein FAM20A golgi associated secretory pathway pseudokinase Fibrillin 1 Fibrinogen alpha chain Fibroblast growth factor 23 Fibronectin Follistatin like 3 Follistatin-related protein 1 Galectin 1 Glypican-3 Golgi membrane protein 1 Growth arrest specific 6 Histidine rich calcium binding protein Insulin like growth factor binding protein 7 Insulin-like growth factor-binding protein 3 Insulin-like growth factor-binding protein 4 Insulin-like growth factor-binding protein 5 Inter-alpha-trypsin inhibitor heavy chain 2 Interleukin-6 Kinectin 1 Kininogen 1 Latent transforming growth factor beta binding protein 1 MIA SH3 domain ER export factor 3 Macrophage colony-stimulating factor 1 Matrilin 3 Matrix extracellular phosphoglycoprotein Matrix remodeling-associated protein 8 Melanotransferrin Membrane bound transcription factor peptidase, site 1 Menin Metalloproteinase inhibitor 1 Milk fat globule EGF and factor V/VIII domain containing Multiple EGF like domains 6 Nucleobindin-1 Patatin like phospholipase domain containing 2 Proenkephalin-A Protein disulfide-isomerase A6 Protein disulfide-isomerase Protein kinase C substrate 80K-H Reticulocalbin 1 SPARC like 1 Secreted phosphoprotein 1 Secreted phosphoprotein 24 Secretogranin-1 Secretogranin-2 Secretogranin-3 Serine protease Serpin family D member 1 Stanniocalcin-2 Sulfhydryl oxidase Tenascin C Trans-golgi network protein 2 Transmembrane protein 132A Uncharacterized protein Uncharacterized protein Uncharacterized protein VGF nerve growth factor inducible Versican core protein Vitamin K-dependent protein C [Wnt protein] O-palmitoleoyl-L-serine hydrolase ferroxidase von Willebrand factor A domain-containing protein 1	A0A0B4J199 A0A8I3MBU3 A0A8I3MBV3 A0A8I3MD84 A0A8I3MKS3 A0A8I3MKU0 A0A8I3MLH1 A0A8I3MRY5 A0A8I3MSG4 A0A8I3MSR8 A0A8I3MVA9 A0A8I3MY68 A0A8I3MZB7 A0A8I3N0D8 A0A8I3N1E6 A0A8I3N365 A0A8I3N3Q6 A0A8I3N5X9 A0A8I3N8F9 A0A8I3N8K1 A0A8I3N8X3 A0A8I3NA54 A0A8I3NAE2 A0A8I3NAG2 A0A8I3NBG6 A0A8I3NBI4 A0A8I3NBI7 A0A8I3NFV4 A0A8I3NH95 A0A8I3NHN1 A0A8I3NHZ1 A0A8I3NIA5 A0A8I3NLT2 A0A8I3NN59 A0A8I3NPQ9 A0A8I3NQA0 A0A8I3NR35 A0A8I3NSE7 A0A8I3NTU0 A0A8I3NXQ1 A0A8I3NY94 A0A8I3P0M4 A0A8I3P1E4 A0A8I3P1V2 A0A8I3P1W2 A0A8I3P261 A0A8I3P2Y2 A0A8I3P735 A0A8I3P7V0 A0A8I3P874 A0A8I3P9H6 A0A8I3PA47 A0A8I3PB34 A0A8I3PED8 A0A8I3PI20 A0A8I3PIK8 A0A8I3PM36 A0A8I3PMB5 A0A8I3PMF7 A0A8I3PPY1 A0A8I3PSD1 A0A8I3PTJ6 A0A8I3PTU8 A0A8I3PU47 A0A8I3PWU3 A0A8I3Q0F7 A0A8I3Q0M1 A0A8I3Q1K1 A0A8I3Q1Q3 A0A8I3Q2P4 A0A8I3Q2T3 A0A8I3Q4H4 A0A8I3Q662 A0A8I3QBE2 A0A8I3QN81 A0A8I3QNP3 A0A8I3RP80 A0A8I3RQL9 A0A8I3RRH5 A0A8I3RT41 A0A8I3RYZ7 A0A8I3S0I3 A0A8I3S0P1 A0A8I3S3D7 A0A8I3S4D1 A0A8I3S5B1 A0A8I3S6A4 A0A8I3S8V0 A0A8I3S915 A1ILJ0 A2SXS5 E2RAK7 F6PLF2 J9PBH8 P18649 P41148 Q28278	ADAM10 AFP AHSG ALB AMBN AMELX AMTN ANO8 APLP2 APOA1 APOA2 APOA5 APOB APOE APP BMP15 BMP4 BPIFB2 C3 CALU CCN1 CDH2 CHGB CHRDL1 CKAP4 COA5 CP CSF1 DMP1 DNAJC3 ENAM F5 FAM20A FAM20C FBN1 FGA FGF23 FGF8B FN1 FSTL1 FSTL3 FUCA2 GAS6 GOLM1 GPC3 GRP94 HRC HSP90B1 HSPC4 IGFBP3 IGFBP4 IGFBP5 IGFBP7 IL6 ITIH2 KNG1 KTN1 LGALS1 LOC102156332 LOC481722 LOC607874 LTBP1 MATN3 MBTPS1 MEGF6 MELTF MEN1 MEPE MFGE8 MIA3 MXRA8 NOTUM NUCB1 P4HB PDIA6 PENK PNPLA2 PRKCSH PROC PRSS23 QSOX1 RCN1 SCG2 SCG3 SERPINA1 SERPINC1 SERPIND1 SPARCL1 SPP1 SPP2 STC2 TGOLN2 TIMP1 TMEM132A TNC TRA1 VCAN VGF VWA1 WFS1	Canis familiaris (dog)
Presynaptic depolarization and calcium channel opening	Calcium voltage-gated channel auxiliary subunit alpha2delta 2 Calcium voltage-gated channel auxiliary subunit alpha2delta 3 Calcium voltage-gated channel auxiliary subunit beta 4 Calcium voltage-gated channel auxiliary subunit gamma 4 Voltage-dependent L-type calcium channel subunit beta-1 Voltage-dependent L-type calcium channel subunit beta-2 Voltage-dependent L-type calcium channel subunit beta-3 Voltage-dependent P/Q-type calcium channel subunit alpha Voltage-dependent R-type calcium channel subunit alpha Voltage-dependent calcium channel gamma-2 subunit	A0A8I3MU54 A0A8I3MZA1 A0A8I3N5F4 A0A8I3NMX5 A0A8I3NPX9 A0A8I3P8U8 A0A8I3PWX4 A0A8I3Q178 A0A8I3Q3U9 A0A8I3S464	CACNA1A CACNA1E CACNA2D2 CACNA2D3 CACNB1 CACNB2 CACNB3 CACNB4 CACNG2 CACNG4	Canis familiaris (dog)
Progressive trimming of alpha-1,2-linked mannose residues from Man9/8/7GlcNAc2 to produce Man5GlcNAc2	alpha-1,2-Mannosidase alpha-1,2-Mannosidase alpha-1,2-Mannosidase	A0A8I3NF57 A0A8I3Q6M3 A0A8I3RVT4	MAN1A1 MAN1A2 MAN1C1	Canis familiaris (dog)	G70323CJ
Prostanoid ligand receptors	Prostaglandin D2 receptor 2 Prostaglandin D2 receptor Prostaglandin E2 receptor EP1 subtype Prostaglandin E2 receptor EP2 subtype Prostaglandin E2 receptor EP3 subtype Prostaglandin E2 receptor EP4 subtype Prostaglandin F2-alpha receptor Thromboxane A2 receptor Uncharacterized protein	A0A8I3MQM7 A0A8I3MUB8 A0A8I3NCM2 A0A8I3NNN1 A0A8I3P5Y8 Q45FN0 Q9BGL8 Q9TU16 Q9XT82	PTGDR PTGDR2 PTGER1 PTGER2 PTGER3 PTGER4 PTGFR PTGIR TBXA2R	Canis familiaris (dog)
RAF/MAP kinase cascade	Actinin alpha 2 Angiopoietin-1 Astrocytic phosphoprotein PEA-15 Colony stimulating factor 2 receptor subunit beta Discs large MAGUK scaffold protein 2 Discs large MAGUK scaffold protein 3 Discs large MAGUK scaffold protein 4 Disks large homolog 1 EF-hand domain-containing protein EGF-like domain-containing protein Epiregulin Fibroblast growth factor 23 Fibroblast growth factor 5 Fibroblast growth factor 7 Fibroblast growth factor receptor 3 Fibroblast growth factor receptor 4 Fibroblast growth factor receptor substrate 2 Fibroblast growth factor receptor substrate 3 Fibroblast growth factor receptor Fibroblast growth factor receptor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibronectin type-III domain-containing protein Fms related receptor tyrosine kinase 3 ligand Focal adhesion kinase 1 GDNF family receptor alpha 4 GDNF family receptor alpha-1 GDNF family receptor alpha-2 GTPase HRas GTPase NRas Glial cell derived neurotrophic factor Glutamate receptor ionotropic, NMDA 1 Glutamate receptor ionotropic, NMDA 2B Glutamate receptor Granulocyte-macrophage colony-stimulating factor Growth factor receptor bound protein 2 Hepatocyte growth factor receptor Hepatocyte growth factor Insulin receptor substrate 1 Insulin receptor substrate 2 Interleukin 5 receptor subunit alpha Interleukin-2 receptor subunit alpha Interleukin-2 receptor subunit beta Interleukin-2 Interleukin-3 Interleukin-5 Kit ligand Klotho beta Klotho Leucine rich repeat containing 7 Mast/stem cell growth factor receptor Kit Mitogen-activated protein kinase Mitogen-activated protein kinase Multifunctional fusion protein Neural cell adhesion molecule 1 Neuregulin 2 Neuregulin 3 Neurofilament light polypeptide Neurturin Persephin Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphoinositide-3-kinase regulatory subunit 2 Platelet-derived growth factor receptor alpha Platelet-derived growth factor receptor beta Platelet-derived growth factor subunit A Platelet-derived growth factor subunit B Pro-epidermal growth factor Pro-neuregulin-1, membrane-bound isoform Proheparin-binding EGF-like growth factor RAS guanyl releasing protein 3 RAS guanyl releasing protein 4 RAS guanyl-releasing protein 1 Ral guanine nucleotide dissociation stimulator like 1 Ral guanine nucleotide dissociation stimulator like 2 Ral guanine nucleotide dissociation stimulator Ran-binding protein 9 Rap guanine nucleotide exchange factor 2 Ras protein specific guanine nucleotide releasing factor 1 Ras protein specific guanine nucleotide releasing factor 2 RasGEF domain family member 1A Receptor protein-tyrosine kinase Receptor protein-tyrosine kinase Receptor protein-tyrosine kinase Receptor protein-tyrosine kinase Receptor-type tyrosine-protein phosphatase alpha Ret proto-onco SHC adaptor protein 2 SHC adaptor protein 3 SHC-transforming protein 1 SOS Ras/Rac guanine nucleotide exchange factor 1 Spectrin alpha, erythrocytic 1 Spectrin alpha, non-erythrocytic 1 Spectrin beta chain Spectrin beta chain Spectrin beta chain Spectrin beta, non-erythrocytic 5 Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein kinase Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein calcium/calmodulin-dependent protein kinase calcium/calmodulin-dependent protein kinase calcium/calmodulin-dependent protein kinase phosphatidylinositol-4,5-bisphosphate 3-kinase phosphatidylinositol-4,5-bisphosphate 3-kinase receptor protein-tyrosine kinase receptor protein-tyrosine kinase small monomeric GTPase	A0A0B4J199 A0A5F4C2B1 A0A7U3JWB8 A0A8I3MHC0 A0A8I3MIK8 A0A8I3MMK3 A0A8I3MN72 A0A8I3MP09 A0A8I3MPK6 A0A8I3MRL6 A0A8I3MSB8 A0A8I3MSQ7 A0A8I3MT80 A0A8I3MVN6 A0A8I3MVS5 A0A8I3MZG1 A0A8I3N0H9 A0A8I3N1N4 A0A8I3N2K8 A0A8I3N488 A0A8I3N790 A0A8I3N8L0 A0A8I3N8T5 A0A8I3N971 A0A8I3N9N3 A0A8I3NAN8 A0A8I3NBU3 A0A8I3NC50 A0A8I3NEF4 A0A8I3NGY1 A0A8I3NHA2 A0A8I3NHF3 A0A8I3NI39 A0A8I3NIS8 A0A8I3NKX5 A0A8I3NLT7 A0A8I3NM39 A0A8I3NMP2 A0A8I3NMY1 A0A8I3NNZ2 A0A8I3NQC1 A0A8I3NQI5 A0A8I3NRB0 A0A8I3NS74 A0A8I3NSK0 A0A8I3NSU7 A0A8I3NTD6 A0A8I3NUU1 A0A8I3NV07 A0A8I3NVH4 A0A8I3NVK5 A0A8I3NVV1 A0A8I3NVW9 A0A8I3NVY0 A0A8I3NWK3 A0A8I3NY81 A0A8I3NYK3 A0A8I3P186 A0A8I3P3X1 A0A8I3P3Z7 A0A8I3P4L9 A0A8I3P6D2 A0A8I3PBB4 A0A8I3PIF6 A0A8I3PJY6 A0A8I3PK39 A0A8I3PS27 A0A8I3PSP7 A0A8I3PT69 A0A8I3PU80 A0A8I3PW06 A0A8I3PWD7 A0A8I3PWT3 A0A8I3PZB5 A0A8I3PZP0 A0A8I3Q1F4 A0A8I3Q1I3 A0A8I3Q314 A0A8I3Q4Z9 A0A8I3Q5L9 A0A8I3QCB4 A0A8I3QHK6 A0A8I3QNS7 A0A8I3RPS3 A0A8I3RQD0 A0A8I3RRH4 A0A8I3RRY0 A0A8I3RS40 A0A8I3RS77 A0A8I3RTN7 A0A8I3RVV0 A0A8I3RWC7 A0A8I3RX48 A0A8I3RYJ5 A0A8I3S0B4 A0A8I3S0I1 A0A8I3S0T0 A0A8I3S0X9 A0A8I3S101 A0A8I3S2P7 A0A8I3S3D9 A0A8I3S3N2 A0A8I3S4U7 A0A8I3S4Z2 A0A8I3S8G3 A0A8I3SAY5 A0A8I3SCP1 E2R534 E2REX2 F1PBJ0 J9P0B3 J9P3I7 J9P8K0 O97799 P48749 P79150 Q06220 Q20FD0 Q29416 Q5R1P0 Q5R1P3 Q6Q7I7 Q867B7 Q95J76 Q9BDX4	ACTN2 ANGPT1 AREG BTC CALM2 CAMK2A CAMK2B CAMK2G CSF2 CSF2RA CSF2RB DLG1 DLG2 DLG3 DLG4 EGF EGFR EPGN ERBB2 ERBB3 ERBB4 EREG FGF1 FGF10 FGF16 FGF17 FGF18 FGF19 FGF20 FGF22 FGF23 FGF3 FGF3A FGF4 FGF4B FGF4C FGF5 FGF6 FGF7 FGF7A FGF7B FGF8 FGF8B FGF9 FGFR1 FGFR2 FGFR3 FGFR4 FLT3 FLT3LG FRS2 FRS3 FYN GDNF GFRA1 GFRA2 GFRA4 GRB2 GRIN1 GRIN2B GRIN2D HBEGF HGF HRAS IL2 IL2RA IL2RB IL3 IL5 IL5RA IRS1 IRS2 JAK1 JAK2 JAK3 KGF KIT KITLG KL KLB KRAS LAT LRRC7 MAPK1 MAPK3 MET MGF NCAM1 NEFL NMDAR1 NRAPGEP NRAS NRG1 NRG2 NRG3 NRTN PDGFA PDGFB PDGFRA PDGFRB PDZGEF1 PEA15 PIK3CA PIK3CB PIK3R1 PIK3R2 PSPN PTK2 PTPRA RALGDS RANBP9 RAPGEF2 RASGEF1A RASGRF1 RASGRF2 RASGRP1 RASGRP3 RASGRP4 RET RGL1 RGL2 RGL3 SHC1 SHC2 SHC3 SOS1 SPTA1 SPTAN1 SPTB SPTBN1 SPTBN2 SPTBN5 TEK TGFA	Canis familiaris (dog)
RHO GTPases regulate CFTR trafficking	Cystic fibrosis transmembrane conductance regulator Cystic fibrosis transmembrane conductance regulator Golgi associated PDZ and coiled-coil motif containing Ras homolog family member Q	A0A8I3Q881 A0A8I3RUU0 A0A8I3RV68 Q5U820	ABCC7 CFTR GOPC RHOQ	Canis familiaris (dog)
RHOQ GTPase cycle	ADP ribosylation factor like GTPase 13B Amino acid transporter Anion exchange protein CDC42 effector protein 1 CDC42 effector protein 3 Caveolin-1 Cdc42 effector protein 2 Cell division control protein 42 homolog Copine 8 Cystic fibrosis transmembrane conductance regulator Cystic fibrosis transmembrane conductance regulator DEP domain containing 1B Diaphanous related formin 3 E3 ubiquitin-protein ligase Formin binding protein 1 GIT ArfGAP 1 GIT ArfGAP 2 Gap junction protein Gfo/Idh/MocA-like oxidoreductase domain containing 1 Golgi associated PDZ and coiled-coil motif containing IQ motif containing GTPase activating protein 3 Intersectin 1 Junction plakoglobin MAGUK p55 subfamily member 7 Oligophrenin-1 Phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 1 Pleckstrin homology and RhoGEF domain containing G3 Ragulator complex protein LAMTOR1 Ras homolog family member Q Ras-related protein Rab-7a Rho GTPase activating protein 17 Rho GTPase activating protein 1 Rho GTPase activating protein 21 Rho GTPase activating protein 32 Rho GTPase activating protein 33 Rho GTPase activating protein 5 Rho GTPase-activating protein 26 Rho GTPase-activating protein 35 Rho GTPase-activating protein 7 Rho guanine nucleotide exchange factor 7 STEAP3 metalloreductase Scribble planar cell polarity protein Stomatin Synapse defective Rho GTPase homolog 1 Synaptosomal-associated protein Thyroid hormone receptor interactor 10 Transferrin receptor protein 1 Uncharacterized protein Uncharacterized protein Vang-like protein Vesicle-associated membrane protein 3 WASP like actin nucleation promoting factor non-specific serine/threonine protein kinase non-specific serine/threonine protein kinase non-specific serine/threonine protein kinase non-specific serine/threonine protein kinase non-specific serine/threonine protein kinase	A0A0A0RBT6 A0A654IEC4 A0A8I3MPB7 A0A8I3MTF5 A0A8I3N1Q4 A0A8I3N1W7 A0A8I3N557 A0A8I3N595 A0A8I3N5X8 A0A8I3N9A3 A0A8I3N9S4 A0A8I3NFM6 A0A8I3NG86 A0A8I3NJ11 A0A8I3NKS6 A0A8I3NL10 A0A8I3NMF7 A0A8I3NXX7 A0A8I3P2J0 A0A8I3P6A5 A0A8I3P789 A0A8I3P7N1 A0A8I3P9Q7 A0A8I3PA52 A0A8I3PA54 A0A8I3PK72 A0A8I3PTG9 A0A8I3PTI9 A0A8I3PXG7 A0A8I3PZK6 A0A8I3Q337 A0A8I3Q4T0 A0A8I3Q637 A0A8I3Q881 A0A8I3QD39 A0A8I3QZ31 A0A8I3RP97 A0A8I3RRC5 A0A8I3RSS1 A0A8I3RSS4 A0A8I3RT56 A0A8I3RUU0 A0A8I3RV68 A0A8I3S1A7 A0A8I3S1Q9 A0A8I3S3A5 A0A8I3S560 A0A8I3S6Y1 A0A8I3S6Z0 A0A8I3SAF2 F1PHV6 I3RSH9 P18067 P33724 P60952 P83509 Q5U820	ABCC7 ARHGAP1 ARHGAP17 ARHGAP21 ARHGAP26 ARHGAP32 ARHGAP33 ARHGAP35 ARHGAP5 ARHGEF7 ARL13B CAV CAV1 CDC42 CDC42BPA CDC42BPB CDC42EP1 CDC42EP2 CDC42EP3 CFTR CPNE8 CXNK1 DEPDC1B DIAPH3 DLC1 FNBP1 GFOD1 GIT1 GIT2 GJA1 GOPC GRLF1 IQGAP3 JUP LAMTOR1 LOC119867035 MPP7 OPHN1 P190A PAK1 PAK2 PAK4 PLEKHG3 PREX1 RAB7 RAB7A RHOQ SCRIB SLC1A5 SLC4A7 SNAP23 SRGAP2 STEAP3 STOM SYDE1 TFRC TRIP10 VAMP3 VANGL1 WASL WWP2 p190ARHOGAP	Canis familiaris (dog)
RUNX1 regulates transcription of genes involved in differentiation of keratinocytes	Procathepsin L Serpin family B member 13	A0A8I3MMH2 Q9GL24	CTSL CTSL1 SERPINB13	Canis familiaris (dog)
Reactions specific to the complex N-glycan synthesis pathway	Alpha-(1,6)-fucosyltransferase Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase Alpha-L-fucosidase Alpha-mannosidase Alpha-mannosidase Carbohydrate sulfotransferase Fucosyltransferase	A0A8I3MHX5 A0A8I3MIH1 A0A8I3NLH2 A0A8I3NVI8 A0A8I3P218 A0A8I3RQC8 A0A8I3RTC2	CHST10 FUCA1 FUT5 FUT8 MAN2A1 MAN2A2 MGAT2	Canis familiaris (dog)	G70323CJ G82576YO
Recycling of bile acids and salts	ABC-type glutathione-S-conjugate transporter Albumin Bile acid-CoA Bile salt export pump Ileal sodium/bile acid cotransporter Nuclear receptor coactivator Nuclear receptor coactivator Nuclear receptor subfamily 1 group H member 4 Retinoic acid receptor RXR Solute carrier family 10 member 1 Solute carrier family 51 subunit alpha Solute carrier family 51 subunit beta Solute carrier organic anion transporter family member Solute carrier organic anion transporter family member StAR related lipid transfer domain containing 5 long-chain-fatty-acid--CoA ligase	A0A8I3MAI7 A0A8I3MLS9 A0A8I3MY68 A0A8I3N1E1 A0A8I3N2S7 A0A8I3NIH7 A0A8I3NUI6 A0A8I3NXT1 A0A8I3PI53 A0A8I3PRC4 A0A8I3PYI4 A0A8I3Q2C1 A0A8I3RTD6 A0A8I3S0X8 B8K1W2 Q70HQ9	ABCC3 ALB Abcb11e BAAT BSEP NCOA1 NCOA2 NR1H4 RXRA SLC10A1 SLC10A2 SLC27A5 SLC51A SLC51B SLCO1A2 SLCO1B2 SLCO1B3 STARD5 slc10a2	Canis familiaris (dog)
Reduction of cytosolic Ca++ levels	Calcium-transporting ATPase Calcium-transporting ATPase Calcium-transporting ATPase Calcium-transporting ATPase Calcium-transporting ATPase Calcium-transporting ATPase EF-hand domain-containing protein Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 Sodium/calcium exchanger 1 Solute carrier family 8 member A2 Solute carrier family 8 member A3 Sorcin	A0A8I3MJQ7 A0A8I3MSQ7 A0A8I3MTJ5 A0A8I3NYA8 A0A8I3PEN3 A0A8I3PJ46 A0A8I3RTF4 A0A8I3RVD4 A0A8I3RY81 A0A8I3S0A4 O46674 P23685	ATP2A1 ATP2A2 ATP2A3 ATP2B1 ATP2B2 ATP2B3 ATP2B4 CALM2 NCX1 SLC8A1 SLC8A2 SLC8A3 SRI	Canis familiaris (dog)
Regulation of Complement cascade	C3a anaphylatoxin chemotactic receptor C4a anaphylatoxin C5a anaphylatoxin chemotactic receptor 1 CD19 molecule Carboxypeptidase B2 Carboxypeptidase N subunit 1 Carboxypeptidase N subunit 2 Clusterin Complement C1q B chain Complement C1q C chain Complement C1q subcomponent subunit A Complement C1s Complement C2 Complement C3 Complement C5 Complement C5a receptor 2 Complement C7 Complement C8 alpha chain Complement C8 gamma chain Complement component C6 Complement component C8 beta chain Complement component C9 Complement factor B Complement factor I Elastase, neutrophil expressed Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein MAC-inhibitory protein Membrane cofactor protein Prothrombin Serpin family G member 1 Sushi domain-containing protein Sushi domain-containing protein Sushi domain-containing protein Sushi domain-containing protein Tetraspanin Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Vitronectin complement subcomponent C1r	A0A8I3MAL2 A0A8I3MBH0 A0A8I3MDV8 A0A8I3MFV5 A0A8I3MKD7 A0A8I3MKJ7 A0A8I3MLF7 A0A8I3MPF4 A0A8I3MQ72 A0A8I3MQK6 A0A8I3MRL7 A0A8I3N180 A0A8I3N567 A0A8I3NC13 A0A8I3NH95 A0A8I3NLH3 A0A8I3NQA0 A0A8I3NQQ5 A0A8I3NT81 A0A8I3NVC1 A0A8I3NWR3 A0A8I3NYS7 A0A8I3P0T6 A0A8I3P1N5 A0A8I3P2M2 A0A8I3P2N6 A0A8I3P3T7 A0A8I3P4X4 A0A8I3P4Y5 A0A8I3P6V2 A0A8I3P941 A0A8I3PD67 A0A8I3PDU9 A0A8I3PJQ7 A0A8I3PL11 A0A8I3PQA6 A0A8I3PT15 A0A8I3PTN6 A0A8I3PTW0 A0A8I3PUA5 A0A8I3PUL5 A0A8I3PUN5 A0A8I3PUP2 A0A8I3PUS1 A0A8I3PUT1 A0A8I3PV91 A0A8I3PVB5 A0A8I3PVC4 A0A8I3PVG3 A0A8I3PWK4 A0A8I3PXN9 A0A8I3PXQ9 A0A8I3PYF1 A0A8I3Q044 A0A8I3Q2F2 A0A8I3Q318 A0A8I3Q5E2 A0A8I3QCV8 A0A8I3QD99 A0A8I3QE86 A0A8I3QF04 A0A8I3RQ73 A0A8I3RQX0 A0A8I3RSI3 A0A8I3RSN2 A0A8I3RUJ7 A0A8I3S0G9 A0A8I3S0K3 A0A8I3S1V7 A0A8I3S6H5 A0A8I3S7V8 A0A8I3S9C3 A0A8I3SAS3 A0A8I3SAS7 P25473 Q8MJD1	C1QA C1QB C1QC C1R C1S C2 C3 C3AR1 C5 C5AR1 C5AR2 C6 C7 C8A C8B C8G C9 CD19 CD55 CD59 CD81 CFB CFH CFHR5 CFI CLU CPB2 CPN1 CPN2 ELA2 ELANE F2 LOC102156626 LOC481722 LOC490269 SEBOX SERPING1	Canis familiaris (dog)
Regulation of Glucokinase by Glucokinase Regulatory Protein	Aladin WD repeat nucleoporin BIG2 domain-containing protein Glucokinase regulator Nuclear pore complex protein Nup85 Nuclear pore complex protein Nup93 Nuclear pore complex protein Nup98-Nup96 Nuclear pore complex protein Nucleoporin 133 Nucleoporin 153 Nucleoporin 155 Nucleoporin 160 Nucleoporin 205 Nucleoporin 214 Nucleoporin 37 Nucleoporin 43 Nucleoporin 50 Nucleoporin 54 Nucleoporin 58 Nucleoporin 62 Nucleoporin 88 Nucleoporin NDC1 Nucleoporin NUP188 Nucleoporin NUP35 Nucleoporin NUP42 Nucleoprotein TPR POM121 transmembrane nucleoporin C Phosphotransferase Protein SEC13 homolog Uncharacterized protein	A0A8I3MJ67 A0A8I3MKP8 A0A8I3MMX0 A0A8I3MS44 A0A8I3MW92 A0A8I3MW93 A0A8I3MZ55 A0A8I3N5H9 A0A8I3N8Q5 A0A8I3N975 A0A8I3N9C4 A0A8I3NAH9 A0A8I3NAY7 A0A8I3NDG5 A0A8I3NIY6 A0A8I3NMR5 A0A8I3NQA4 A0A8I3NV53 A0A8I3NZW0 A0A8I3P0U9 A0A8I3P537 A0A8I3P769 A0A8I3PAE6 A0A8I3PBR9 A0A8I3PUC1 A0A8I3Q2U4 A0A8I3S484 A0A8I3S533 A0A8I3S9D7	AAAS GCK GCKR NDC1 NUP107 NUP133 NUP153 NUP155 NUP160 NUP188 NUP205 NUP210 NUP214 NUP35 NUP37 NUP42 NUP43 NUP50 NUP54 NUP58 NUP62 NUP85 NUP88 NUP93 NUP98 POM121C RANBP2 SEC13 TPR	Canis familiaris (dog)	G58161NS
Regulation of IFNG signaling	Fibronectin type-III domain-containing protein Interferon gamma Protein inhibitor of activated STAT 1 Signal transducer and activator of transcription Small ubiquitin-related modifier 1 Suppressor of cytokine signaling 3 Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein phosphatase non-receptor type Uncharacterized protein	A0A8I3MY73 A0A8I3MZ64 A0A8I3NU62 A0A8I3NVH4 A0A8I3NZS0 A0A8I3P2U6 A0A8I3PSA1 A0A8I3QCJ0 A0A8I3RS40 P42161	IFNG IFNGR1 IFNGR2 JAK1 JAK2 PIAS1 PTPN2 SOCS3 STAT1 SUMO1	Canis familiaris (dog)
Regulation of IGF Activity by IGFBP	Albumin Alpha 1 antitrypsin Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase A Alpha-2-HS-glycoprotein Alpha-L-fucosidase Alpha-fetoprotein Ameloblastin Amelogenin X isoform Amelotin Amyloid beta precursor like protein 2 Amyloid-beta A4 protein Anoctamin Antithrombin-III Apolipoprotein A-I Apolipoprotein A-II Apolipoprotein A-V Apolipoprotein B Apolipoprotein E Apolipoprotein L3 Apolipoprotein L3 BPI fold containing family B member 2 Bone morphogenetic protein 4 C4a anaphylatoxin CCN family member 1 Cadherin-2 Calumenin Chordin like 1 Coagulation factor V Complement C3 Cytoskeleton associated protein 4 Dentin matrix acidic phosphoprotein 1 Disintegrin and metalloproteinase domain-containing protein 10 DnaJ homolog subfamily C member 3 Enamelin Endoplasmin FAM20 C-terminal domain-containing protein FAM20A golgi associated secretory pathway pseudokinase Fibrillin 1 Fibrinogen alpha chain Fibroblast growth factor 23 Fibronectin Follistatin like 3 Follistatin-related protein 1 Galectin 1 Glypican-3 Golgi membrane protein 1 Growth arrest specific 6 Histidine rich calcium binding protein Insulin like growth factor binding protein 6 Insulin like growth factor binding protein 7 Insulin-like growth factor I Insulin-like growth factor II Insulin-like growth factor-binding protein 2 Insulin-like growth factor-binding protein 3 Insulin-like growth factor-binding protein 4 Insulin-like growth factor-binding protein 5 Inter-alpha-trypsin inhibitor heavy chain 2 Interleukin-6 Kinectin 1 Kininogen 1 Latent transforming growth factor beta binding protein 1 MIA SH3 domain ER export factor 3 Macrophage colony-stimulating factor 1 Matrilin 3 Matrix extracellular phosphoglycoprotein Matrix remodeling-associated protein 8 Melanotransferrin Membrane bound transcription factor peptidase, site 1 Menin Metalloproteinase inhibitor 1 Milk fat globule EGF and factor V/VIII domain containing Multiple EGF like domains 6 Nucleobindin-1 Pappalysin 1 Pappalysin 2 Patatin like phospholipase domain containing 2 Proenkephalin-A Protein disulfide-isomerase A6 Protein disulfide-isomerase Protein kinase C substrate 80K-H Reticulocalbin 1 SPARC like 1 Secreted phosphoprotein 1 Secreted phosphoprotein 24 Secretogranin-1 Secretogranin-2 Secretogranin-3 Serine protease Serpin family D member 1 Stanniocalcin-2 Sulfhydryl oxidase Tenascin C Trans-golgi network protein 2 Transmembrane protein 132A Uncharacterized protein Uncharacterized protein Uncharacterized protein VGF nerve growth factor inducible Versican core protein Vitamin K-dependent protein C [Wnt protein] O-palmitoleoyl-L-serine hydrolase ferroxidase von Willebrand factor A domain-containing protein 1	A0A0B4J199 A0A8I3MBU3 A0A8I3MBV3 A0A8I3MD84 A0A8I3MKS3 A0A8I3MKU0 A0A8I3MLH1 A0A8I3MRY5 A0A8I3MSG4 A0A8I3MSR8 A0A8I3MVA9 A0A8I3MY68 A0A8I3MZB7 A0A8I3N0D8 A0A8I3N1E6 A0A8I3N365 A0A8I3N3Q6 A0A8I3N5X9 A0A8I3N8F9 A0A8I3N8K1 A0A8I3N8X3 A0A8I3N9A4 A0A8I3NA54 A0A8I3NAE2 A0A8I3NAG2 A0A8I3NBG6 A0A8I3NBI4 A0A8I3NBI7 A0A8I3NFV4 A0A8I3NH95 A0A8I3NHN1 A0A8I3NHZ1 A0A8I3NI15 A0A8I3NIA5 A0A8I3NLM1 A0A8I3NLT2 A0A8I3NN59 A0A8I3NPQ9 A0A8I3NQA0 A0A8I3NR35 A0A8I3NSE7 A0A8I3NTU0 A0A8I3NXQ1 A0A8I3NY94 A0A8I3P0M4 A0A8I3P1E4 A0A8I3P1V2 A0A8I3P1W2 A0A8I3P261 A0A8I3P2Y2 A0A8I3P735 A0A8I3P7V0 A0A8I3P874 A0A8I3P9H6 A0A8I3PA47 A0A8I3PB34 A0A8I3PED8 A0A8I3PEI1 A0A8I3PI20 A0A8I3PIK8 A0A8I3PM36 A0A8I3PMB5 A0A8I3PMF7 A0A8I3PPY1 A0A8I3PSD1 A0A8I3PTJ6 A0A8I3PTU8 A0A8I3PU47 A0A8I3PWU3 A0A8I3PX33 A0A8I3Q0F7 A0A8I3Q0M1 A0A8I3Q1K1 A0A8I3Q1Q3 A0A8I3Q2P4 A0A8I3Q2T3 A0A8I3Q4H4 A0A8I3Q662 A0A8I3QBE2 A0A8I3QN81 A0A8I3QNP3 A0A8I3RP80 A0A8I3RQL9 A0A8I3RRH5 A0A8I3RT41 A0A8I3RYZ7 A0A8I3S0I3 A0A8I3S0P1 A0A8I3S3D7 A0A8I3S4D1 A0A8I3S5B1 A0A8I3S6A4 A0A8I3S8V0 A0A8I3S915 A1ILJ0 A2SXS5 E2RAK7 F6PLF2 J9PBH8 P18649 P33712 P41148 Q28278	ADAM10 AFP AHSG ALB AMBN AMELX AMTN ANO8 APLP2 APOA1 APOA2 APOA5 APOB APOE APP BMP15 BMP4 BPIFB2 C3 CALU CCN1 CDH2 CHGB CHRDL1 CKAP4 COA5 CP CSF1 DMP1 DNAJC3 ENAM F5 FAM20A FAM20C FBN1 FGA FGF23 FGF8B FN1 FSTL1 FSTL3 FUCA2 GAS6 GOLM1 GPC3 GRP94 HRC HSP90B1 HSPC4 IGF1 IGF2 IGFBP2 IGFBP3 IGFBP4 IGFBP5 IGFBP6 IGFBP7 IGFIA IL6 ITIH2 KNG1 KTN1 LGALS1 LOC102156332 LOC481722 LOC607874 LTBP1 MATN3 MBTPS1 MEGF6 MELTF MEN1 MEPE MFGE8 MIA3 MXRA8 NOTUM NUCB1 P4HB PAPPA PAPPA2 PDIA6 PENK PNPLA2 PRKCSH PROC PRSS23 QSOX1 RCN1 SCG2 SCG3 SERPINA1 SERPINC1 SERPIND1 SPARCL1 SPP1 SPP2 STC2 TGOLN2 TIMP1 TMEM132A TNC TRA1 VCAN VGF VWA1 WFS1	Canis familiaris (dog)
Regulation of KIT signaling	E3 ubiquitin-protein ligase CBL Growth factor receptor bound protein 2 Kit ligand Mast/stem cell growth factor receptor Kit Protein kinase C SH2B adaptor protein 2 SH2B adaptor protein 3 SOS Ras/Rac guanine nucleotide exchange factor 1 Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein phosphatase non-receptor type	A0A8I3MBU4 A0A8I3ML64 A0A8I3MTK2 A0A8I3NAC6 A0A8I3P3X1 A0A8I3PT69 A0A8I3PUN0 A0A8I3PUQ8 A0A8I3PWC6 A0A8I3QRG3 A0A8I3S3D9 A0A8I3SBF9 O97799 Q06220	CBL FYN GRB2 KIT KITLG LCK LYN MGF PRKCA PTPN6 SH2B2 SH2B3 SOS1 SRC YES1	Canis familiaris (dog)
Regulation of TNFR1 signaling	Baculoviral IAP repeat containing 2 Baculoviral IAP repeat-containing protein 3 CAP-Gly domain containing linker protein 3 Caspase 8 Caspase 9 E2 ubiquitin-conjugating enzyme E2 ubiquitin-conjugating enzyme E2 ubiquitin-conjugating enzyme E3 ubiquitin-protein ligase CHIP E3 ubiquitin-protein ligase XIAP IkappaB kinase Inhibitor of nuclear factor kappa B kinase subunit epsilon Inhibitor of nuclear factor kappa-B kinase subunit alpha MAP kinase-activating death domain protein NF-kappa-B essential modulator Optineurin RBR-type E3 ubiquitin transferase RING-type E3 ubiquitin transferase RanBP-type and C3HC4-type zinc finger-containing protein 1 Receptor interacting serine/threonine kinase 1 Serine/threonine-protein kinase Signal peptide peptidase like 2A Signal peptide peptidase like 2B Small ribosomal subunit protein RACK1 Spermatogenesis associated 2 TANK binding kinase 1 TNF receptor-associated factor TNFR-Cys domain-containing protein Tax1 binding protein 1 Tumor necrosis factor receptor type 1-associated DEATH domain protein Tumor necrosis factor Ubiquitin B Ubiquitin carboxyl-terminal hydrolase CYLD Ubiquitin carboxyl-terminal hydrolase Ubiquitin carboxyl-terminal hydrolase Ubiquitin carboxyl-terminal hydrolase Ubiquitin conjugating enzyme E2 D3 Ubiquitin-like domain-containing protein Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein ubiquitinyl hydrolase 1 ubiquitinyl hydrolase 1 ubiquitinyl hydrolase 1	A0A8I3MA34 A0A8I3MAP5 A0A8I3MDM0 A0A8I3MJ82 A0A8I3MKR0 A0A8I3MLM6 A0A8I3MMN5 A0A8I3MQC7 A0A8I3MSL4 A0A8I3MYA4 A0A8I3N1V1 A0A8I3N4F2 A0A8I3NEJ2 A0A8I3NFB9 A0A8I3NK16 A0A8I3NLZ9 A0A8I3NP69 A0A8I3NS04 A0A8I3P2P4 A0A8I3P499 A0A8I3PLX1 A0A8I3PRU0 A0A8I3PS24 A0A8I3PT83 A0A8I3PW29 A0A8I3PWL6 A0A8I3PZS6 A0A8I3Q155 A0A8I3Q3L1 A0A8I3QYD0 A0A8I3RSQ2 A0A8I3RUY7 A0A8I3RZA9 A0A8I3RZI9 A0A8I3S2L7 A0A8I3S5W5 A0A8I3S792 A0A8I3S794 A1E2V0 P51742 P63050 Q38IV1 Q38JA9	BIRC2 BIRC3 BIRC4 CASP8 CASP9 CHUK CLIP3 CYLD IKBKB IKBKE IKBKG IRF9 MADD MIB2 OPTN OTUD1 OTUD7B RACK1 RBCK1 RIPK1 RPS27A SPATA2 SPPL2A SPPL2B STUB1 TAX1BP1 TBK1 TNF TNFA TNFAIP3 TNFRSF1A TNFSF2 TRADD TRAF2 UBA52 UBB UBC UBCEP2 UBE2D1 UBE2D2 UBE2D3 UBE2L3 ULK1 USP2 USP21 USP4 XIAP	Canis familiaris (dog)
Regulation of actin dynamics for phagocytic cup formation	Abl interactor 1 Abl interactor 2 Actin gamma 1 Actin, cytoplasmic 1 Actin-related protein 2/3 complex subunit 3 Actin-related protein 2/3 complex subunit 4 Actin-related protein 2/3 complex subunit 5 Actin-related protein 2/3 complex subunit Actin-related protein 2/3 complex subunit Actin-related protein 2 Actin-related protein 3 Adapter molecule crk Arp2/3 complex 34 kDa subunit Brain-specific angiogenesis inhibitor 1-associated protein 2 CYRIA/CYRIB Rac1 binding domain-containing protein Cell division control protein 42 homolog Cytoplasmic FMR1-interacting protein Cytoplasmic protein Dedicator of cytokinesis 1 Engulfment and cell motility 1 Engulfment and cell motility 2 Fc fragment of IgG receptor Ia Focal adhesion kinase 1 Growth factor receptor bound protein 2 Heat shock protein HSP 90-alpha Heat shock protein HSP 90-beta Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein LIM domain kinase 1 Low affinity immunoglobulin gamma Fc region receptor III-A Low affinity immunoglobulin gamma Fc region receptor III-A Mitogen-activated protein kinase Mitogen-activated protein kinase Myosin IC Myosin IXB Myosin VA Myosin X Myosin-2 Myosin-9 NCK associated protein 1 like NCK interacting protein with SH3 domain NF2, moesin-ezrin-radixin like (MERLIN) tumor suppressor Nck-associated protein 1 Ras-related C3 botulinum toxin substrate 1 Ras-related C3 botulinum toxin substrate 1 T-cell surface glycoprotein CD3 gamma chain T-cell surface glycoprotein CD3 zeta chain Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein kinase Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Vav guanine nucleotide exchange factor 1 Vav guanine nucleotide exchange factor 2 Vav guanine nucleotide exchange factor 3 WAS/WASL interacting protein family member 1 WASP like actin nucleation promoting factor Wiskott-Aldrich syndrome protein family member Wiskott-Aldrich syndrome protein family member Wiskott-Aldrich syndrome protein family member non-specific serine/threonine protein kinase	A0A8I3MFY1 A0A8I3MIN4 A0A8I3MKB3 A0A8I3ML42 A0A8I3MNR2 A0A8I3MPK0 A0A8I3MR78 A0A8I3MV98 A0A8I3MVD4 A0A8I3N156 A0A8I3N1W7 A0A8I3N9N7 A0A8I3N9V3 A0A8I3NA65 A0A8I3NC73 A0A8I3NE73 A0A8I3NEM6 A0A8I3NEW9 A0A8I3NEZ8 A0A8I3NGQ0 A0A8I3NGY2 A0A8I3NH46 A0A8I3NMF7 A0A8I3NMY1 A0A8I3NNZ1 A0A8I3NU35 A0A8I3NVZ2 A0A8I3NWR3 A0A8I3NZ88 A0A8I3NZQ2 A0A8I3P1N5 A0A8I3P2M2 A0A8I3P2N6 A0A8I3P3G0 A0A8I3P3T7 A0A8I3P4X4 A0A8I3P4Y5 A0A8I3P6V2 A0A8I3P7Z3 A0A8I3P8D4 A0A8I3P8Q3 A0A8I3P941 A0A8I3PD67 A0A8I3PDU9 A0A8I3PGP9 A0A8I3PL11 A0A8I3PPQ5 A0A8I3PQA6 A0A8I3PT15 A0A8I3PT69 A0A8I3PTN6 A0A8I3PUA5 A0A8I3PUN5 A0A8I3PUP2 A0A8I3PUS1 A0A8I3PV91 A0A8I3PVB5 A0A8I3PVC4 A0A8I3PVG3 A0A8I3PWK4 A0A8I3PXN0 A0A8I3PXN9 A0A8I3PXQ9 A0A8I3PYF1 A0A8I3PZH0 A0A8I3PZP0 A0A8I3Q1Q8 A0A8I3Q2I4 A0A8I3Q5E2 A0A8I3Q9N2 A0A8I3QBP5 A0A8I3QCV8 A0A8I3QD99 A0A8I3QE86 A0A8I3QF04 A0A8I3QHH1 A0A8I3QQ00 A0A8I3RQD0 A0A8I3RQZ5 A0A8I3RVS9 A0A8I3RXY6 A0A8I3S0G9 A0A8I3S0K3 A0A8I3S4H5 A0A8I3S602 A0A8I3S6D8 A0A8I3S6H5 A0A8I3S9C3 A0A8I3SAS3 A0A8I3SAS7 A0A8I3SAU8 E2RP87 O18840 P60952 P62999 Q076A7	ABI1 ABI2 ABL1 ACTB ACTG1 ACTR2 ACTR3 ARPC1A ARPC1B ARPC2 ARPC3 ARPC4 ARPC5 BAIAP2 BTK CD247 CD3G CDC42 CRK CYFIP1 CYFIP2 DOCK1 ELMO1 ELMO2 FCGR1A FCGR2B FCGR3A GRB2 HSP90AA1 HSP90AB1 LIMK1 LOC478984 MAPK1 MAPK3 MYH2 MYH9 MYO10 MYO1C MYO5A MYO9B NCK1 NCKAP1 NCKAP1L NCKIPSD NF2 PAK1 PTK2 RAC1 SYK VAV1 VAV2 VAV3 WASF1 WASF2 WASF3 WASL WIPF1	Canis familiaris (dog)

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