GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **76 - 100** of **597** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol ▼	Organism	GlyTouCan ID
GPVI-mediated activation cascade	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma 3-phosphoinositide-dependent protein kinase 1 Cdc42 homolog PI-3 kinase Pi3K21B, isoform B Protein vav Putative inactive tyrosine-protein kinase Wsck RH14395p Ras-like GTP-binding protein Rho1 Ras-related protein Rac1 Ras-related protein Rac2	P40792 P40793 P48148 P48554 P83097 P91634 Q7KTZ2 Q9NHV9 Q9VAA1 Q9VXH3 Q9W0V1	Cdc42 DP110 DPLCgamma Dmel\CG15529 Dmel\CG2699 Dmel\CG4141 Dmel\CG4200 Dmp110 Dp110 Dp110/PI3K Dp60 Dpp110 P60 PI(3)K PI-3 kinase PI-3-K PI3 kinase PI3'K PI3K PI3K-92D PI3K-92E/Dp110 PI3K-Dp110 PI3K-I PI3K-dp110 PI3K-p60 PI3K-reg PI3K21B PI3K92E PI3k PI[[3]]K PLC PLC&ygr: PLC-gamma PLC-gamma D PLC-gammaD PLCgamma PLCgamma1 PLCgammaDmel Pdk1 Pi3K Pi3K21B Pi3K92D Pi3K92E Pi3K92E p110 Pi3Kp110 Pi3Kp60 Pi3k Pi3k21B Pi3k92e PiK92E Pk61C Plcgamma Rac1 Rac2 RacA RacB Rho1 Sl Vav Wsck anon-92Ed dP110 dP13K dP60 dPI3K dPI3K[92E] deltap60 dp110 dp110alpha dp60 dpP110 droPIK57 p110 p120 p145 p60 p85 pi3k pi3k92E pi3k92e plc-gamma plc-gammad rea sl type-1 PI3K	Drosophila melanogaster (fruit fly)
Drug-mediated inhibition of ERBB2 signaling	Epidermal growth factor receptor Heat shock protein 83 Hsp90 co-chaperone Cdc37	P02828 P04412 Q24276	Cdc37 DER E(sev)3B Egfr Hsp82 Hsp83 Hsp90 c-erbB top	Drosophila melanogaster (fruit fly)
Calnexin/calreticulin cycle	Calnexin 99A, isoform A Calreticulin Protein disulfide-isomerase (Fragment)	P29413 Q3YMU0 Q9VAL7	Calr Cnx Cnx99A Cnx99A-RD Cnx99a Crc D-ERp60 Dmel\CG11958 Dmel\CG8983 ERp60 ERp60-RA Erp60 Ov6 anon-EST:fe3D9 cnx cnx99A dERp60	Drosophila melanogaster (fruit fly)
O-linked glycosylation	Dystroglycan 1 Protein O-mannosyl-transferase 2 Protein O-mannosyltransferase 1	A0A0C4DHF6 Q9VTK2 Q9W5D4	CT41273 DG Dg DmDG Dmel\CG18250 POMT1 Pomt2 alpha-DG atu dg dgn dys rt tw	Drosophila melanogaster (fruit fly)
EPH-Ephrin signaling	Ephrin receptor protein-tyrosine kinase	Q9V4E1 Q9V4E5	CT3831 DEK Dek Dek7 Deph Dmel\CG1511 Dmel\CG1862 Ek7 Eph Ephrin RPTK Dek7 dek eph ephrin lincRNA.922 lincRNA.923	Drosophila melanogaster (fruit fly)
Regulation of HMOX1 expression and activity	Heme oxygenase SD07518p	Q9VGJ9 Q9VPQ7	CT34507 DmHO DmSPP Dmel\CG11840 Dmel\CG14716 HO HO-1 HOX Ho SPP Spp dHO ho shanti spp	Drosophila melanogaster (fruit fly)
Class B/2 (Secretin family receptors)	Furrowed, isoform A Hig-anchoring scaffold protein, isoform G Latrophilin Cirl Locomotion-related protein Hikaru genki	A1Z7G7 B7YZX0 Q09101 Q9VYR4	CT28647 CT3745 Cirl Dmel\CG10186 Dmel\CG1500 Hasp anon-EST:Posey189 fw fw-like hasp hig wr	Drosophila melanogaster (fruit fly)
NCAM signaling for neurite out-growth	Chromosomal serine/threonine-protein kinase JIL-1 Cyclic AMP response element-binding protein B Growth factor receptor-bound protein 2 Karst, isoform E Mitogen-activated protein kinase ERK-A Protein son of sevenless Ras-like protein 1 Spectrin alpha chain Spectrin beta chain Tyrosine-protein kinase Src64B Tyrosine-protein phosphatase Lar protein-tyrosine-phosphatase	A1ZAB3 A8JNJ6 P00528 P08646 P13395 P16621 P26675 P40417 Q00963 Q08012 Q9V3I5 Q9VWW0	CT18044 CrebB CrebB-17A DPTP52F Dmel\CG12008 Dmel\CG18243 E(sev)2B ERKa Grb2 JIL-1 Karst Kst Lar MAPK PTP52F Ptp52F Ptp52F-RB Ras1 Ras85D SPEC-A Sos Spec-b Spec-beta[[H]] Src1 Src64B alpha-Spec beta-Spec beta-Spectrin betaH betaH-Spec betaH-spectrin betaHS betaHSpec beta[[H]] beta[[H]]-SPEC beta[[H]]-Sp beta[[H]]-Spec beta[[H]]-Spectrin beta[[H]]spectrin beta[[Heavy]]spectrin beta[[heavy]]-Spec beta[[heavy]]-Spectrin beta[[heavy]]spectrin betah-Spec drk kst l(3)01318 ptp52F rl	Drosophila melanogaster (fruit fly)
Toll Like Receptor 10 (TLR10) Cascade	MstProx Protein toll Tehao, isoform A Toll-4 Toll-9, isoform A	P08953 Q9VIA4 Q9VJX9 Q9VLE6 Q9VPH1	CT17508 CT22017 CT29238 Dm Toll-9 DmMstProx Dmel\CG1149 Dmel\CG18241 Dmel\CG5528 Dmel\CG7121 MstProx Mstprox TL4 TLR4 TOLL 9 Tak/Toll-like Tehao Tho Tl Tl-3 Tl-4 Tl-5 Tl-9 Toll Toll 5 Toll 9 Toll-3 Toll-4 Toll-5 Toll-6 Toll-9 Toll4 Toll5 Toll9 dTLR3 dTLR4 dTLR5 dTLR9 dToll3 dToll4 dToll5 dToll9 mstprox tehao toll	Drosophila melanogaster (fruit fly)
Transport of nucleotide sugars	Adenosine 3'-phospho 5'-phosphosulfate transporter 1 Adenosine 3'-phospho 5'-phosphosulfate transporter 2 EG GDP-fucose transporter 1 UDP-sugar transporter UST74c UDP-xylose and UDP-N-acetylglucosamine transporter	O76865 Q95YI5 Q9VEI3 Q9VHT4 Q9VVD9 Q9W429	CSAT Csat DmNST DmUGT Dmel\CG2675 EG:100G10.5 Efr Gfr PAPST1 Papst2 UDP-Gal/UDP-GalNAc UST74C Ugalt anon-3Bb dNST-1 dNST-2 frc nac sll ugt	Drosophila melanogaster (fruit fly)
Transcription regulation of cwo gene	Circadian locomoter output cycles protein kaput Protein cycle Transcription factor cwo	O61734 O61735 Q9VGZ5	CLOCK Clk PAS1 cwo cyc jrk	Drosophila melanogaster (fruit fly)
Transcription activation by CLK:CYC and repression by VRI	Circadian locomoter output cycles protein kaput GH23983p PAR domain protein 1-delta Protein cycle	O61734 O61735 Q24217 Q9VMS4	CLOCK Clk DM1 DM16 DM32 Dmel\CG14029 Dmel\CG17888 PAS1 PDP PDP-1epsilon PDP1 PDP1 epsilon PDP1epsilon Pdp-1 Pdp1 Pdp1 epsilon Pdp1&e:gr Pdp1e Pdp1epsilon VRI Vri anon-WO0140519.206 argo cyc jf23 jrk l(2)25Db l(2)jf23 mat(2)ea-G mat(2)earlyRS32 mel_pdp1 mel_vri pdp pdp1 pdp1epsilon vri	Drosophila melanogaster (fruit fly)
Transcription repression by PER and activation by PDP1	Circadian locomoter output cycles protein kaput Discs overgrown protein kinase GH23983p PAR domain protein 1-delta Period circadian protein Protein cycle Protein timeless	O61734 O61735 O76324 P07663 P49021 Q24217 Q9VMS4	CLOCK Clk DM1 DM16 DM32 Dmel\CG14029 Dmel\CG17888 PAS1 PDP PDP-1epsilon PDP1 PDP1 epsilon PDP1epsilon Pdp-1 Pdp1 Pdp1 epsilon Pdp1&e:gr Pdp1e Pdp1epsilon VRI Vri anon-WO0140519.206 argo cyc dbt dco jf23 jrk l(2)25Db l(2)jf23 mat(2)ea-G mat(2)earlyRS32 mel_pdp1 mel_vri pdp pdp1 pdp1epsilon per tim vri	Drosophila melanogaster (fruit fly)
Activation of SMO	Casein kinase I isoform alpha G protein-coupled receptor kinase 1 Protein smoothened	P32865 P54367 P91682	CKI CkIalpha Gprk-1 Gprk1 smo	Drosophila melanogaster (fruit fly)
Assembly of receptor complex	Frizzled-2 Frizzled Low-density lipoprotein receptor-related protein Protein wingless non-specific serine/threonine protein kinase	P09615 P18537 Q86BR9 Q95V09 Q9VVX3	CK1 CK1-gamma CK1[[gamma]] CK1gamma CKI-related CKIgamma Dmel\CG6963 Gish Hrr25 NEST:bs27c08 Spider anon-WO0118547.425 arr fz fz2 gish ms(3)89B spider wg	Drosophila melanogaster (fruit fly)
Phosphorylation of ARR	Frizzled-2 Frizzled Low-density lipoprotein receptor-related protein Protein kinase shaggy Protein wingless non-specific serine/threonine protein kinase	P09615 P18431 P18537 Q86BR9 Q95V09 Q9VVX3	CK1 CK1-gamma CK1[[gamma]] CK1gamma CKI-related CKIgamma Dmel\CG6963 Gish Hrr25 NEST:bs27c08 Spider anon-WO0118547.425 arr fz fz2 gish gsk3 ms(3)89B sgg spider wg zw3	Drosophila melanogaster (fruit fly)
Receptor-type tyrosine-protein phosphatases	AT31531p Chaoptin Liprin-alpha, isoform E Protein singed wings 2 Protein windpipe Tyrosine-protein phosphatase Lar protein-tyrosine-phosphatase	A1ZAB3 M9PCD4 P12024 P16621 Q8SXT3 Q9VU88 Q9W266	CHT CT18044 DLiprin DLiprin-alpha DPTP52F Dliprin-alpha Dmel\CG10743 Dmel\CG11199 Dmel\CG18243 LIP LIP.1 LIP1 LPR Lar Liprin Liprin-alpha Liprin-beta PTP52F Ptp52F Ptp52F-RB chp lip-alpha liprin liprin-alpha lpr oos ptp52F swi2 wdp	Drosophila melanogaster (fruit fly)
Lewis blood group biosynthesis	Alpha-(1,3)-fucosyltransferase B Glycoprotein 3-alpha-L-fucosyltransferase A Hexosyltransferase Hexosyltransferase Hexosyltransferase Hexosyltransferase Protein valois	A1Z8R4 A1Z8R5 A1Z8R6 Q95RP8 Q9VIP8 Q9VLC1 Q9VUL9	CG8976 DmGalT1 Dmel\CG30036 Dmel\CG30037 Dmel\CG3038 Dmel\CG33145 EG:BACR37P7.1 FucTA FucTB GalT1 GalT3 dbeta3GnT vls vsl	Drosophila melanogaster (fruit fly)	G81971FM G90387AM G98173LG
Collagen degradation	Alanine--glyoxylate aminotransferase 2-like Collagen alpha-1(IV) chain Matrix metalloproteinase 1, isoform C Matrix metalloproteinase-2	P08120 Q8MPP3 Q9VU95 Q9W122	CG8745 Cg25C Col4a1 DCg1 Dm1-MMP Dmel\CG4859 MMP MMP-1 MMP1 MMp1 Mmp 1 Mmp-1 Mmp1 Mmp2 dMMP1 dm1-MMP dmmp1 l(2)k04809 mmp-1 mmp1	Drosophila melanogaster (fruit fly)
Progressive trimming of alpha-1,2-linked mannose residues from Man9/8/7GlcNAc2 to produce Man5GlcNAc2	Mannosyl-oligosaccharide alpha-1,2-mannosidase IA alpha-1,2-Mannosidase	P53624 Q8IMK0	CG7880 Dmel\CG31202 alpha-Man-Ia alpha-Man-Ic alpha-man-1 dMas-2 mas-1 mas-2	Drosophila melanogaster (fruit fly)	G70323CJ
GABA synthesis, release, reuptake and degradation	Complexin DnaJ homolog subfamily C member 5 homolog Glutamate decarboxylase Heat shock 70 kDa protein cognate 4 Protein ROP Rab3 interacting molecule, isoform F Ras-related protein Rab-3 Synaptobrevin Synaptosomal-associated protein 25 Synaptosomal-associated protein Synaptotagmin 1 Syntaxin-1A Vesicular GABA transporter	A0A0B4K6M2 A1Z9M6 P11147 P18489 P20228 P21521 P25228 P36975 Q03751 Q07327 Q24547 Q8IPM8 Q9VH76	CG7301 CG7305 CG7321 CG8394.2 Csp DRIM DmRIM Dmel\CG33547 Dmel\CG8394 Dmel\CG9474 Gad Gad1 Glb Hsc4 Hsc70-4 RIM Rab3 Rim Rop SNAP-24 SNAP-25b SNAP24 Snap24 Snap25 Snap25b Syb Syt1 Syx1A UNC-10/RIM VGAT VIAAT Vgat cpx cs1 dm-Rim rim rim-1 syt syx-1A vGAT	Drosophila melanogaster (fruit fly)
SIRT1 negatively regulates rRNA expression	Histone H2A.v Histone H2A Histone H2A Histone H2B Histone H3.3A Histone H3.3B Histone H3 Histone H4 Histone-lysine N-methyltransferase Su(var)3-9 NAD-dependent histone deacetylase sirtuin-1 Ribosomal RNA-processing protein 8	C0HL66 C0HL67 P02283 P02299 P08985 P45975 P84040 P84051 Q4AB57 Q7K2B0 Q9VK34	CG7137 Dmel\CG33853 Dmel\CG33856 Dmel\CG33859 H2AvD H2a H4 H4r His2A His2A:CG31618 His2A:CG33808 His2A:CG33814 His2A:CG33817 His2A:CG33820 His2A:CG33823 His2A:CG33826 His2A:CG33829 His2A:CG33832 His2A:CG33835 His2A:CG33838 His2A:CG33841 His2A:CG33844 His2A:CG33847 His2A:CG33850 His2A:CG33853 His2A:CG33856 His2A:CG33859 His2A:CG33862 His2A:CG33865 His2Av His2AvD His2B His2B:CG17949 His2B:CG33868 His2B:CG33870 His2B:CG33872 His2B:CG33874 His2B:CG33876 His2B:CG33878 His2B:CG33880 His2B:CG33882 His2B:CG33884 His2B:CG33886 His2B:CG33888 His2B:CG33890 His2B:CG33892 His2B:CG33894 His2B:CG33896 His2B:CG33898 His2B:CG33900 His2B:CG33902 His2B:CG33904 His2B:CG33906 His2B:CG33908 His2B:CG33910 His3 His3.3A His3.3B His3:CG31613 His3:CG33803 His3:CG33806 His3:CG33809 His3:CG33812 His3:CG33815 His3:CG33818 His3:CG33821 His3:CG33824 His3:CG33827 His3:CG33830 His3:CG33833 His3:CG33836 His3:CG33839 His3:CG33842 His3:CG33845 His3:CG33848 His3:CG33851 His3:CG33854 His3:CG33857 His3:CG33860 His3:CG33863 His3:CG33866 His4 His4:CG31611 His4:CG33869 His4:CG33871 His4:CG33873 His4:CG33875 His4:CG33877 His4:CG33879 His4:CG33881 His4:CG33883 His4:CG33885 His4:CG33887 His4:CG33889 His4:CG33891 His4:CG33893 His4:CG33895 His4:CG33897 His4:CG33899 His4:CG33901 His4:CG33903 His4:CG33905 His4:CG33907 His4:CG33909 His4r KMT1 Sir2 Sirt1 Su(var)3-9	Drosophila melanogaster (fruit fly)
Dermatan sulfate biosynthesis	Heparan sulfate 2-O-sulfotransferase pipe Insulin-like growth factor-binding protein complex acid labile subunit Kon-tiki, isoform B	Q86BJ3 Q9VJ82 Q9VT89	CG6590 CT20492 CT28869 Dmel\CG10275 Dmel\CG32055 Kon kon perd pip	Drosophila melanogaster (fruit fly)
CS/DS degradation	Alpha-L-iduronidase Iduronate 2-sulfatase Insulin-like growth factor-binding protein complex acid labile subunit Kon-tiki, isoform B Probable beta-hexosaminidase fdl beta-N-acetylhexosaminidase beta-N-acetylhexosaminidase	Q0E8H9 Q8WSF3 Q9VJ82 Q9VKJ8 Q9VT89 Q9VZP8 Q9W3C4	CG6590 CT20492 CT28869 DmHex1 DmHex2 Dmel\CG10275 Dmel\CG12014 Dmel\CG1318 Dmel\CG1787 Dmel\CG32055 HEX 1 HEX 2 HEX1 HEX2 HEXO1 HEXO2 Hexo1 Hexo2 IDS Ids Idua Kon anon-EST:Posey282 fdl kon perd	Drosophila melanogaster (fruit fly)	G27025MB
Vitamin C (ascorbate) metabolism	Cytochrome b5 Glucose transporter type 1 Glutathione S transferase O1 Glutathione S transferase O2, isoform A Glutathione S transferase O3 LD30822p Pyrimidodiazepine synthase cytochrome-b5 reductase	Q8IRI6 Q9V4N3 Q9VH02 Q9VSL2 Q9VSL3 Q9VSL5 Q9VSL6 Q9VWK8	CG6293-RA CG6673-A CG6673-B CG6673A CG6673B Cyt-b5 DmGSTO1 DmGSTO2a DmGSTO2b DmGSTO3 Dmel\CG6293 Dmel\CG6662 Dmel\CG6673 Dmel\CG6776 Dmel\CG7914 GSTO1 GSTO2 GSTO2a GSTO2b GSTO3 Glut1 GstO1 GstO2 GstO3 T14 anon-EST:Posey29 dGstO1 gsto2 se	Drosophila melanogaster (fruit fly)

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