GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	November 12, 2024
ECODAB	April 1, 2019

Displaying entries **51 - 75** of **270** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol	Organism	GlyTouCan ID
Ion homeostasis	ATP-sensitive inward rectifier potassium channel 11 Calcium-transporting ATPase Calcium-transporting ATPase Cardiac phospholamban FXYD domain-containing ion transport regulator Inositol 1,4,5-trisphosphate receptor Plasma membrane calcium-transporting ATPase 1 Short transient receptor potential channel 1 Sodium/calcium exchanger 1 Sodium/potassium-transporting ATPase subunit beta-3 Solute carrier family 8 member A2 Solute carrier family 8 member A3 Stromal interaction molecule 1 calcium/calmodulin-dependent protein kinase	A0A1D5NWP2 A0A1D5PZT6 A0A1L1RKB7 A0A3Q2U0I3 F1NBC9 F1NGS8 F1P023 F1P1X4 P33879 Q000J5 Q5ZM59 Q6DMS2 Q98SH2 R4GK80	ATP1B3 ATP2A2 ATP2B1 ATP2B2 CAMK2A COX16 ITPR2 KCNJ11 NCX1 PLN PMCA1 RCJMB04_3a16 SLC8A1 SLC8A2 STIM1 TRPC1	Gallus gallus (chicken)
Signaling by Insulin receptor	Insulin Tyrosine-protein kinase receptor	A0A1D5P6T3 P67970	INS INSR	Gallus gallus (chicken)
FGFR1c and Klotho ligand binding and activation	Fibroblast growth factor receptor 1 Fibroblast growth factor	P21804 R4GIR0	CEK1 FGF23 FGFR1	Gallus gallus (chicken)
B-WICH complex positively regulates rRNA expression	Actin, cytoplasmic 1 DEK proto-onco DNA-directed RNA polymerase II subunit E DNA-directed RNA polymerase subunit beta DNA-directed RNA polymerases I, II, and III subunit RPABC2 DNA-directed RNA polymerases I, II, and III subunit RPABC5 Histone H2A-IV Histone H2A.J Histone H2A.V Histone H2A Histone H2A Histone H2A Histone H2B 1/2/3/4/6 Histone H2B 5 Histone H2B 7 Histone H2B 8 Histone H2B Histone H2B Histone H3.2 Histone H3.3 Histone H4 Splicing factor 3b subunit 1 TATA box-binding protein-associated factor RNA polymerase I subunit B TATA-box-binding protein	A0A1D5PW04 A0A1D5PY49 A0A1L1RNY8 A0A3Q2UDI2 E1BSY6 E1C2C3 F1NDD7 F1NHV9 F1P5G5 P02263 P02272 P0C1H3 P0C1H4 P0C1H5 P60706 P62801 P70082 P84229 P84247 Q5F422 Q5ZJR9 Q6JLB1 Q9PSW9 Q9PT88	ACTB DEK H2A-IX H2AF H2AFX H2AZ2 H2B-I H2B-II H2B-III H2B-IV H2B-V H2B-VI H2B-VII H2B-VIII H3-I H3-II H3-III H3-IV H3-IX H3-V H3-VI H3-VII H3-VIII H3-X H4-I H4-II H4-III H4-IV H4-V H4-VI H4-VII HIST1H2B5L LOC100859381 LOC426037 POLR1B POLR2E POLR2L RPB6 SF3B1 TAF1B TBP	Gallus gallus (chicken)
Platelet Aggregation (Plug Formation)	Glycoprotein IX platelet Glycoprotein Ib platelet subunit beta Tsukushi	A0A3Q3AXX7 F1P1G3 Q65Z91	GP1BB GP9 LRRC54 TSK TSKU	Gallus gallus (chicken)
Class A/1 (Rhodopsin-like receptors)	Chemerin-like receptor 1 G protein-coupled receptor 55 G protein-coupled receptor 65 G-protein coupled receptor 39 G-protein coupled receptors family 1 profile domain-containing protein Melatonin receptor 1B Melatonin receptor type 1A N-arachidonyl glycine receptor Platelet-activating factor receptor Succinate receptor 1	A0A0A0MQ60 A0A1D5P7P2 A0A3Q2U480 A1XWZ9 E1C095 F1NA96 F1NJ83 F1NRF0 P49285 R4GHJ0	CMKLR1 GPR132 GPR18 GPR39 GPR55 GPR65 MTNR1B PTAFR SUCNR1	Gallus gallus (chicken)
Interferon alpha/beta signaling	ATP binding cassette subfamily E member 1 Interferon alpha Interferon type A1/A2 Interferon type B Interferon Karyopherin subunit beta 1 Polyubiquitin-B Signal transducer and activator of transcription Suppressor of cytokine signaling 1 Suppressor of cytokine signaling 3 Tyrosine-protein kinase Ubiquitin B Ubiquitin-ribosomal protein eS31 fusion protein	A0A1D5P1W7 A0A1D5P546 B0FLN7 B6RCQ2 F1NMJ9 P0CG62 P42165 P79781 Q5ZJK3 Q5ZJX6 Q90873 Q9PWI5 R4GJH9	ABCE1 IFN-gamma IFN2 IFNA IFNA1 IFNA2 IFNA3 IFNB JAK1 KPNB1 LOC100857947 LOC100858506 LOC100859414 LOC768614 RCJMB04_17i9 RPS27A SOCS1 SOCS3 UBA80 UBB	Gallus gallus (chicken)
Biosynthesis of EPA-derived SPMs	Prostaglandin G/H synthase 2	P27607	CEF-147 PTGS2	Gallus gallus (chicken)
Activated NTRK3 signals through PI3K	NT-3 growth factor receptor Neurotrophin-3 Proto-oncogene tyrosine-protein kinase Src	A0A3Q2U804 P00523 Q91044	NTF3 NTRK3 SRC TRKC	Gallus gallus (chicken)
Assembly of active LPL and LIPC lipase complexes	Lipoprotein lipase Uncharacterized protein furin	A0A1L1RJC1 P11602 Q91000	FURIN LOC101747868 LPL	Gallus gallus (chicken)
PI3K/AKT Signaling	3-phosphoinositide-dependent protein kinase 1 Acyl-coenzyme A thioesterase THEM4 Amphiregulin BDNF/NT-3 growth factors receptor Betacellulin Brain-derived neurotrophic factor Epigen Epiregulin Fibroblast growth factor 10 Fibroblast growth factor 1 Fibroblast growth factor 2 Fibroblast growth factor 3 Fibroblast growth factor receptor 1 Fibroblast growth factor receptor 2 Fibroblast growth factor receptor 3 Fibroblast growth factor receptor substrate 2 Fibroblast growth factor receptor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Growth factor receptor-bound protein 2 Kit ligand Mast/stem cell growth factor receptor Kit NT-3 growth factor receptor Neuregulin 2 Neurotrophin-3 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphoinositide 3-kinase adapter protein 1 Phosphoinositide-3-kinase regulatory subunit 2 Platelet-derived growth factor subunit A Proheparin-binding EGF-like growth factor Proto-oncogene tyrosine-protein kinase Src RAC-alpha serine/threonine-protein kinase RPTOR independent companion of MTOR complex 2 Ras homolog family member G Ras-related C3 botulinum toxin substrate 1 Receptor protein-tyrosine kinase Serine/threonine-protein kinase Sgk1 Serine/threonine-protein kinase TOR T cell receptor associated transmembrane adaptor 1 Target of rapamycin complex 2 subunit MAPKAP1 Tyrosine-protein kinase Tyrosine-protein phosphatase non-receptor type 11 Uncharacterized protein phosphatidylinositol-4,5-bisphosphate 3-kinase phosphatidylinositol-4,5-bisphosphate 3-kinase	A0A1D5PKH0 A0A1D5PVP0 A0A3Q2TTH8 A0A3Q2U4X3 A0A3Q2U639 A0A3Q2U804 A0A3Q3ACS4 A3R0S3 E1BZW7 E1C021 E1C2C5 F1NCL8 F1NHX1 F1NJR9 F1NMJ6 F1NRE1 F1NUX4 F1P5Y5 P00523 P18460 P18461 P19596 P21804 P25429 P48800 P48801 Q08156 Q09108 Q197G3 Q4R0X9 Q5EG71 Q5F337 Q5F3U4 Q5F4A2 Q5KRA4 Q645M5 Q64EU6 Q6LC82 Q6U1I9 Q90687 Q90WK2 Q91044 Q91987 Q9DDT2 Q9I950 Q9W6S3 Q9W7C5 R4GH73 R4GIR0 R4GMA6 R4GMB5	AKT1 AREG BCAP BDNF BTC CEK1 CEK2 CEK3 EGFR EPGN EREG FGF-18 FGF-3 FGF1 FGF10 FGF18 FGF19 FGF2 FGF23 FGF3 FGF4 FGF6 FGF7 FGF8 FGFR1 FGFR2 FGFR3 FGFR4 FRS2 FYN Fgf16 Fgf7 GRB2 HBEGF HEGFL KIT KITLG MAPKAP1 MTOR NRG2 NTF3 NTRK2 NTRK3 PDGF-A (L) PDGFA PIK3AP1 PIK3CB PIK3CD PIK3R1 PIK3R2 PTPN11 RCJMB04_38b23 RCJMB04_6p10 RHOG RICTOR SCF SGK SGK1 SIN1 SRC THEM4 TRAT1 TRKB TRKC cRac1A	Gallus gallus (chicken)
Regulation of IFNA/IFNB signaling	Interferon alpha Interferon type A1/A2 Interferon type B Interferon Signal transducer and activator of transcription Tyrosine-protein kinase Tyrosine-protein phosphatase non-receptor type 11 protein-tyrosine-phosphatase	A0A1I7Q402 B0FLN7 F1NMJ9 P42165 Q5ZJK3 Q90687 Q90873 Q9PWI5	IFN-gamma IFN2 IFNA IFNA1 IFNA2 IFNA3 IFNB JAK1 LOC100857947 LOC100858506 LOC100859414 LOC768614 PTPN1 PTPN11 RCJMB04_17i9	Gallus gallus (chicken)
Synthesis of 15-eicosatetraenoic acid derivatives	Hydroperoxide isomerase ALOXE3 Prostaglandin G/H synthase 2	A0A1L1RTQ1 P27607	ALOX15B CEF-147 PTGS2	Gallus gallus (chicken)
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell	Beta-2-microglobulin CD1.2 antigen CD300 molecule like family member g CD40 ligand CD48 CXADR Ig-like cell adhesion molecule Cell surface glycoprotein CD200 receptor 1-A Ig-like domain-containing protein Integrin subunit alpha 4 KRAB domain containing zinc finger protein MHC BF1 class I MHC class I alpha chain 2 Triggering receptor expressed on myeloid cells 2 Uncharacterized protein	A0A1D5PIR0 A0A1D5PKL9 A0A1D5PLP7 A0ZXL5 F1NBK7 F1NSL7 K4L906 P21611 Q2YHT7 Q52Z74 Q5ZKJ6 Q95601 Q9I8D8 R4GFS8	B-FIV B2M BF1 BF2 BFIV21 CD1.2 CD1A2 CD200R1A CD300LG CD40L CD40LG CD48 ITGA4 KRABZFP RCJMB04_10g5 TNFSF5 TREM2 TSTD1	Gallus gallus (chicken)
ESR-mediated signaling	peptidylprolyl isomerase peptidylprolyl isomerase	A0A3Q2U9P1 Q646T7	FKBP4 FKBP5 FKBP51	Gallus gallus (chicken)
RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function	Core-binding factor beta subunit Histone H2A-IV Histone H2A.J Histone H2A.V Histone H2A Histone H2A Histone H2A Histone H2B 1/2/3/4/6 Histone H2B 5 Histone H2B 7 Histone H2B 8 Histone H2B Histone H2B Histone H3.2 Histone H3.3 Histone H4 Histone deacetylase 1 RB binding protein 5, histone lysine methyltransferase complex subunit Runt-related transcription factor SIN3 transcription regulator family member A SIN3 transcription regulator family member B Uncharacterized protein	A0A1D5PY49 A0A1L1RNY8 A0A3Q2TTQ9 A0A3Q2UDI2 E1BX21 F1NDD7 F1NMJ8 F1NQP4 F1P5G5 P02263 P02272 P0C1H3 P0C1H4 P0C1H5 P56517 P62801 P70082 P84229 P84247 Q5ZIL1 Q5ZLX3 Q9PSW9	CBFB H2A-IX H2AF H2AFX H2AZ2 H2B-I H2B-II H2B-III H2B-IV H2B-V H2B-VI H2B-VII H2B-VIII H3-I H3-II H3-III H3-IV H3-IX H3-V H3-VI H3-VII H3-VIII H3-X H4-I H4-II H4-III H4-IV H4-V H4-VI H4-VII HDAC1 HDAC1A HIST1H2B5L LOC100859381 LOC426037 RBBP5 RCJMB04_25e24 RUNX1 SIN3A SIN3B	Gallus gallus (chicken)
FGFR3c ligand binding and activation	Fibroblast growth factor 1 Fibroblast growth factor 2 Fibroblast growth factor receptor 3 Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Polypeptide N-acetylgalactosaminyltransferase	E1BZW7 E1C241 P18460 P19596 P48800 Q197G3 Q4R0X9 Q9I950 R4GIR0	CEK2 FGF-18 FGF1 FGF18 FGF2 FGF23 FGF4 FGF8 FGFR3 Fgf16 GALNT3	Gallus gallus (chicken)
Stimuli-sensing channels	Acid-sensing ion channel 1 Anoctamin Bestrophin homolog Bestrophin homolog Chloride channel protein E3 ubiquitin-protein ligase Osteopetrosis associated transmembrane protein 1 Polyubiquitin-B RAF proto-oncogene serine/threonine-protein kinase Serine/threonine-protein kinase Sgk1 Serine/threonine-protein kinase Sgk3 Serum/glucocorticoid regulated kinase 2 Sodium channel epithelial 1 subunit gamma Sodium leak channel, non-selective Stomatin like 3 Stomatin Two pore segment channel 1 Ubiquitin B Ubiquitin-ribosomal protein eS31 fusion protein	A0A1D5P0N6 A0A1D5P546 A0A1D5P6F6 E1BQ97 E1BSL8 E1BTV1 E1BZK5 E1C882 F1NGF2 F1NW62 F1P588 P05625 P0CG62 P79781 Q1XA76 Q5F372 Q5ZJQ4 Q5ZMW4 Q6U1I9	ACCN2 ANO10 ASIC1 BEST3 BEST4 CATSPER4 CLCN4 MIL NALCN OSTM1 RAF1 RCJMB04_16g8 RPS27A SCNN1G SGK SGK1 SGK2 STOM STOML3 UBA80 UBB WWP1	Gallus gallus (chicken)
Synthesis, secretion, and deacylation of Ghrelin	Appetite-regulating hormone Insulin-like growth factor I Insulin Pro-glucagon Signal peptidase complex catalytic subunit SEC11 Signal peptidase complex subunit 3 Somatotropin	P08998 P18254 P28687 P67970 P68259 Q5ZMQ3 Q8AV73	GCG GH GHRL IGF1 INS SEC11A SPC22 SPCS3 ghr ghre	Gallus gallus (chicken)	G58161NS
G2/M DNA damage checkpoint	BRISC and BRCA1-A complex member 2 Histone H2A Histone H2A Histone H2A Histone H2B 1/2/3/4/6 Histone H2B 5 Histone H2B 7 Histone H2B 8 Histone H2B Histone H2B Histone H4 Protein inhibitor of activated STAT 4	A0A1D5P2D1 A0A1D5PY49 A0A1L1RNY8 A0A3Q2UDI2 F1NDD7 F1P5G5 P0C1H3 P0C1H4 P0C1H5 P62801 Q5ZML0 Q9PSW9	BABAM2 BRE H2AFX H2B-I H2B-II H2B-III H2B-IV H2B-V H2B-VI H2B-VII H2B-VIII H4-I H4-II H4-III H4-IV H4-V H4-VI H4-VII HIST1H2B5L LOC100859381 LOC426037 PIAS4	Gallus gallus (chicken)
Condensation of Prophase Chromosomes	Histone H2A-IV Histone H2A.J Histone H2A.V Histone H2A Histone H2A Histone H2A Histone H2B 1/2/3/4/6 Histone H2B 5 Histone H2B 7 Histone H2B 8 Histone H2B Histone H2B Histone H4 RB transcriptional corepressor 1 Serine/threonine-protein kinase PLK	A0A1D5PY49 A0A1L1RNY8 A0A3Q2UDI2 A0A3Q3AS57 F1NCX7 F1NDD7 F1P5G5 P02263 P02272 P0C1H3 P0C1H4 P0C1H5 P62801 P70082 Q9PSW9	H2A-IX H2AF H2AFX H2AZ2 H2B-I H2B-II H2B-III H2B-IV H2B-V H2B-VI H2B-VII H2B-VIII H4-I H4-II H4-III H4-IV H4-V H4-VI H4-VII HIST1H2B5L LOC100859381 LOC426037 PLK1 RB1	Gallus gallus (chicken)
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks	BRISC and BRCA1-A complex member 2 Eyes absent homolog Eyes absent homolog Eyes absent homolog Histone H2A Histone H2A Histone H2A Histone H2B 1/2/3/4/6 Histone H2B 5 Histone H2B 7 Histone H2B 8 Histone H2B Histone H2B Histone H4 Polyubiquitin-B Protein inhibitor of activated STAT 4 SUMO-conjugating enzyme UBC9 Small ubiquitin-related modifier 1 Stress-activated protein kinase JNK Ubiquitin B Ubiquitin-ribosomal protein eS31 fusion protein [histone H3]-trimethyl-L-lysine(9) demethylase [histone H3]-trimethyl-L-lysine(9) demethylase	A0A1D5NXI7 A0A1D5P2D1 A0A1D5P546 A0A1D5PC43 A0A1D5PGP0 A0A1D5PY49 A0A1L1RNY8 A0A3Q2TSH5 A0A3Q2TY19 A0A3Q2UDI2 E1C6D5 F1NDD7 F1P5G5 P0C1H3 P0C1H4 P0C1H5 P0CG62 P62801 P63283 P79781 Q5ZML0 Q8QGH2 Q9PSW9	BABAM2 BRE EYA1 EYA2 EYA4 H2AFX H2B-I H2B-II H2B-III H2B-IV H2B-V H2B-VI H2B-VII H2B-VIII H4-I H4-II H4-III H4-IV H4-V H4-VI H4-VII HIST1H2B5L KDM4A KDM4B LOC100859381 LOC426037 MAPK8 PIAS4 RPS27A SUMO1 UBA80 UBB UBC9 UBCE9 UBE2I	Gallus gallus (chicken)
TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway	B-cell-activating factor BAFF CD40 ligand TNF receptor-associated factor	A0A3Q3AAA5 Q8JHJ4 Q9I8D8	BAFF CD40L CD40LG TNFSF13B TNFSF5 TRAF3	Gallus gallus (chicken)
Metabolism of folate and pterines	Dihydrofolate reductase Proton-coupled folate transporter Reduced folate transporter Solute carrier family 25 member 32 methylenetetrahydrofolate reductase (NADPH)	A0A1D5PVR1 A0A1D5PZX4 A3RKL3 E1BXL1 F1NJ67	DHFR MTHFR PCFT SLC19A1 SLC25A32 SLC46A1	Gallus gallus (chicken)
A tetrasaccharide linker sequence is required for GAG synthesis	Beta-1,4-galactosyltransferase Decorin Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase Glypican-1 Syndecan-4 Syndecan Syndecan Xylosyltransferase 2	A0A1D5P9Q8 A0A1L1RX77 F1NU53 F1NV24 F1P150 P49416 Q2HPN7 Q8JIY0	B3GAT2 B4GAL-T7 DCN GPC1 SDC1 SDC2 SDC4 XYLT2	Gallus gallus (chicken)

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