GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	November 12, 2024
ECODAB	April 1, 2019

Displaying entries **1 - 25** of **270** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol	Organism ▲	GlyTouCan ID
N-Glycan antennae elongation	Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase A Alpha-2,8-sialyltransferase Beta-1,4-galactosyltransferase Beta-1,4-galactosyltransferase MGAT4 family member C ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6 alpha-1,6-mannosyl-glycoprotein 6-beta-N-acetylglucosaminyltransferase	A0A1D5PEI3 A0A1D5PSH8 A0A3S5ZPV4 F1NEL5 Q5F407 Q6ZXD0 R4GKF3	B4GALT2 B4GALT6 LOC427873 MGAT4A MGAT5 SIAT8C ST8SIA6	Gallus gallus (chicken)	G81533KY
Pentose phosphate pathway	6-phosphogluconate dehydrogenase, decarboxylating 6-phosphogluconolactonase Ribokinase Transaldolase Transketolase	A0A1D5PC23 F1N8A7 F1P1A5 Q5ZIZ0 Q5ZJY1	RBKS RCJMB04_14h20 RCJMB04_22k15 TALDO1 TKTL1	Gallus gallus (chicken)	G31080DL
Regulated proteolysis of p75NTR	Nuclear factor NF-kappa-B p105 subunit Presenilin-1 Presenilin TNF receptor-associated factor Tumor necrosis factor alpha converting enzyme Tumor necrosis factor receptor superfamily member 16	E1C626 F1NGP7 P18519 Q04861 Q4JIM4 Q5QHR9	ADAM17 NFKB1 NGFR PSEN1 PSEN2 TNFRSF16 TRAF6	Gallus gallus (chicken)
MyD88:TIRAP-dependent cascade initiated on plasma membrane	Interleukin-1 receptor-associated kinase 4 Interleukin-1 receptor-associated kinase-like 2 Lymphocyte antigen 96 Myeloid differentiation primary response protein MyD88 Toll-like receptor 1-like protein b Toll-like receptor 1 Toll-like receptor 2 type-1 Toll-like receptor 4 Toll/interleukin-1 receptor domain-containing adapter protein	A0A8V0XHS1 A5H0S2 A5HNF6 Q4U127 Q5F382 Q5WA51 Q5ZJM6 Q7ZTG5 Q9DD78	LY96 MYD88 RCJMB04_17b10 RCJMB04_29d24 TIRAP TLR1 TLR1Lb TLR2-1 TLR4	Gallus gallus (chicken)
Iron uptake and transport	Cullin 1 Cullin-associated NEDD8-dissociated protein 1 Cytoplasmic aconitate hydratase Ferritin heavy chain Iron-responsive element-binding protein 2 Plasma membrane ascorbate-dependent reductase CYBRD1 Polyubiquitin-B Proton-coupled folate transporter S-phase kinase-associated protein 1 Solute carrier family 40 member Ubiquitin B Ubiquitin-ribosomal protein eS31 fusion protein	A0A1D5P2L3 A0A1D5P546 A0A1D5PBJ1 A0A1D5PQ17 A0A1D5PQV0 F1NHL2 F1NJ67 P08267 P0CG62 P79781 Q5F3K3 Q5ZKF5	ACO1 CAND1 CUL1 CYBRD1 FTH IREB2 PCFT RPS27A SKP1 SKP1A SLC40A1 SLC46A1 UBA80 UBB	Gallus gallus (chicken)
Oxidative Stress Induced Senescence	Cyclin dependent kinase 6 Cyclin dependent kinase inhibitor 2B Cyclin dependent kinase inhibitor 2C E3 ubiquitin-protein ligase RING2 Histone H2A-IV Histone H2A.J Histone H2A.V Histone H2A Histone H2A Histone H2A Histone H2B 1/2/3/4/6 Histone H2B 5 Histone H2B 7 Histone H2B 8 Histone H2B Histone H2B Histone H3.2 Histone H3.3 Histone H4 MAPK activated protein kinase 2 MAPK activated protein kinase 3 Mitogen-activated protein kinase 9 Polycomb complex protein BMI-1 Polycomb protein EED Protein c-Fos RB binding protein 4, chromatin remodeling factor Stress-activated protein kinase JNK Thioredoxin mitogen-activated protein kinase kinase kinase mitogen-activated protein kinase kinase mitogen-activated protein kinase kinase mitogen-activated protein kinase	A0A1D5NVP0 A0A1D5P1F4 A0A1D5PD64 A0A1D5PIQ5 A0A1D5PTJ8 A0A1D5PY49 A0A1L1RNY8 A0A3Q2TY19 A0A3Q2U1E9 A0A3Q2UDI2 F1NCY7 F1NDD7 F1NLF9 F1P5G5 F2Z4M0 P02263 P02272 P08629 P0C1H3 P0C1H4 P0C1H5 P11939 P62801 P70082 P79996 P84229 P84247 Q5SDR3 Q5ZKH3 Q7ZT27 Q90771 Q9PSW9	BMI1 CDK6 CDKN2B CDKN2C EED FOS H2A-IX H2AF H2AFX H2AZ2 H2B-I H2B-II H2B-III H2B-IV H2B-V H2B-VI H2B-VII H2B-VIII H3-I H3-II H3-III H3-IV H3-IX H3-V H3-VI H3-VII H3-VIII H3-X H4-I H4-II H4-III H4-IV H4-V H4-VI H4-VII HIST1H2B5L JNK2 LOC100859381 LOC426037 MAP2K3 MAP2K4 MAP3K5 MAPK14 MAPK8 MAPK9 MAPKAPK2 MAPKAPK3 PCGF4 RBBP4 RNF2 TXN cdk6	Gallus gallus (chicken)
TLR4 cascade	Lymphocyte antigen 96 Monocyte differentiation antigen CD14 Toll-like receptor 4	A0A8V0XHS1 B0BL87 Q7ZTG5	Cd14 LY96 TLR4	Gallus gallus (chicken)
Response to elevated platelet cytosolic Ca2+	Protein kinase C Protein kinase C	A0A1D5PUY5 R4GHL2	PRKCA PRKCB	Gallus gallus (chicken)
SHC-mediated cascade:FGFR2	Fibroblast growth factor 10 Fibroblast growth factor 1 Fibroblast growth factor 2 Fibroblast growth factor 3 Fibroblast growth factor receptor 2 Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor GTPase HRas GTPase NRas Growth factor receptor-bound protein 2 SHC-transforming protein 1 SOS Ras/Rac guanine nucleotide exchange factor 1 small monomeric GTPase	A0A1D5NYP8 A0A1D5PEZ2 A0A1D5PT95 A0A3Q2TTH8 A3R0S3 E1BZW7 F1P5Y5 P08642 P18461 P19596 P48800 P48801 Q197G3 Q4R0X9 Q5F352 Q5KRA4 Q9I950 R4GIR0	CEK3 FGF-18 FGF-3 FGF1 FGF10 FGF18 FGF2 FGF23 FGF3 FGF4 FGF6 FGF7 FGF8 FGFR2 Fgf16 Fgf7 GRB2 HRAS HRAS1 KRAS NRAS SHC1 SOS1	Gallus gallus (chicken)
P2Y receptors	Lysophosphatidic acid receptor 4 P2Y purinoceptor 1 P2Y purinoceptor 3	E1BWJ9 P34996 Q98907	LPAR4 P2RY1 P2RY3	Gallus gallus (chicken)
NFG and proNGF binds to p75NTR	Tumor necrosis factor receptor superfamily member 16	P18519	NGFR TNFRSF16	Gallus gallus (chicken)
Fructose biosynthesis	Sorbitol dehydrogenase	P0DMQ6	SORD	Gallus gallus (chicken)	G58161NS
G alpha (q) signalling events	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase 5-hydroxytryptamine receptor 2A 5-hydroxytryptamine receptor 2B 5-hydroxytryptamine receptor 2C Alpha-1A adrenergic receptor Alpha-1B adrenergic receptor Alpha-1D adrenergic receptor Appetite-regulating hormone B1 bradykinin receptor Bombesin receptor subtype-3 C-C motif chemokine 4 homolog C-C motif chemokine C-X3-C motif chemokine ligand 1 CCXC chemokine receptor 1 like Chemokine Chemokine Chemokine Chemokine Cholecystokinin receptor type A Coagulation factor II thrombin receptor like 2 Cysteinyl leukotriene receptor 1 Cysteinyl leukotriene receptor 2 Endothelin-1 receptor Endothelin-2 F2R like trypsin receptor 1 G protein subunit beta 3 G protein subunit beta 4 G protein subunit gamma 13 G protein-coupled receptor 103-va1 G protein-coupled receptor 65 G-protein coupled receptor 39 G-protein coupled receptors family 1 profile domain-containing protein Gastrin-releasing peptide Glutamate metabotropic receptor 1 Glutamate receptor, metabotropic 5 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Guanine nucleotide-binding protein subunit alpha Guanine nucleotide-binding protein subunit alpha Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Histamine H1 receptor Hypocretin neuropeptide precursor Lysophosphatidic acid receptor 1 Lysophosphatidic acid receptor 3 Lysophosphatidic acid receptor 4 Mesotocin/neurophysin I prepropeptide Motilin receptor Muscarinic acetylcholine receptor Neuromedin B Neuromedin U receptor 2 Neuromedin U receptor type 1 Neuromedin U Neuromedin-B receptor Neuromedin-K receptor Neuromedin-S Neuropeptide FF receptor 1 Neuropeptide S receptor Neuropeptide S Neurotensin receptor 1 Oxytocin receptor P2Y purinoceptor 1 P2Y purinoceptor 3 PMCH Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphoinositide-3-kinase regulatory subunit 2 Platelet-activating factor receptor Preprourotensin II Pro-glucagon Pro-thyrotropin-releasing hormone Progonadoliberin-1 Prokineticin 2 Prostaglandin F2-alpha receptor Regulator of G-protein signaling 17 Regulator of G-protein signaling 18 Regulator of G-protein signaling 2 Regulator of G-protein signaling 4 Regulator of G-protein signaling 5 Substance-P receptor Tachykinin 1 Thromboxane A2 receptor Thyrotropin-releasing hormone receptor Type 1/III gonadotropin-releasing hormone receptor hexahelical variant Type-1 angiotensin II receptor Urotensin-2 receptor non-specific serine/threonine protein kinase	A0A1D5NZL7 A0A1D5NZW8 A0A1D5P3F4 A0A1D5P7R6 A0A1D5P7Z5 A0A1D5PAZ6 A0A1D5PKZ0 A0A1D5PLZ8 A0A1D5PRZ3 A0A2I6J485 A0A3Q2U0G2 A0A3Q2U9B6 A0A3Q2U9J5 A0A3Q3ACS4 A0A3S5ZPM8 A0ZPS0 A1XWZ9 B0FMV4 B0FMV6 B2CL09 B2KSC0 B5G4W1 E1BRP1 E1BVI5 E1BW98 E1BWJ9 E1BWP2 E1BX29 E1BYD3 E1BYR3 E1C095 E1C1U6 E1C2C5 E1C482 E1C5A6 E1C733 E1C795 E1C7F2 E7FKE5 F1N989 F1NBM2 F1NEH2 F1NEN2 F1NHZ4 F1NIZ5 F1NJ82 F1NJ83 F1NLV4 F1NP50 F1NP52 F1NU82 F1NWG3 F1NWH4 F1P0I0 F1P0W5 F1P147 F1P148 F1P166 F1P2V3 F1P4F9 F6T4Q1 O73739 P01295 P34996 P37042 P68259 P79785 Q38Q38 Q5D7U5 Q5F3B5 Q5F4D0 Q5IEZ5 Q5ZJ03 Q6Q2J6 Q6ZXC3 Q702H5 Q71RI7 Q75XU5 Q7ZZS5 Q802E6 Q8AV73 Q90826 Q98907 Q9PWA0 Q9W6I3 R4GFT9 R4GHJ0 R4GKD1 R4GKX0	ADRA1A ADRA1B ADRA1D AGTR1 ASPR BDKRB1 BRS3.5 CCK1R CCKAR CCL26 CCL4 CCLL4 CCLi10 CCLi7 CCLi8 CCLi9 CCXCR1-L CHRM5 CX3CL1 CYSLTR1 CYSLTR2 EDN2 EDNRA F2RL1 F2RL2 GCG GHRL GNA11 GNAQ GNB1 GNB3 GNB4 GNG10 GNG12 GNG13 GNG2 GNG5 GNGT2 GNRH1 GNRHR1/III GPR103 GPR132 GPR39 GPR65 GRM1 GRM5 GRP HCRT HRH1 HTR2A HTR2B HTR2C HTR2b LPAR1 LPAR3 LPAR4 MLNR MT NMB NMBR NMS NMU NMUR1 NMUR2 NPFF1 NPSR1 NTSR1 OXT OXTR P2RY1 P2RY3 PIK3R1 PIK3R2 PLCB1 PLCB4 PMCH PROK2 PTAFR PTGFR QRFPR RGS17 RGS18 RGS2 RGS4 RGS5 SCYA4 TAC1 TACR1 TACR3 TBXA2R TRH TRHR TRIO UTS2 UTS2R ghr ghre tac1	Gallus gallus (chicken)
HDACs deacetylate histones	GATA zinc finger domain containing 2A High mobility group 20B Histone H2A-IV Histone H2A.J Histone H2A Histone H2B 1/2/3/4/6 Histone H2B 5 Histone H2B 7 Histone H2B 8 Histone H2B Histone H2B Histone H3.2 Histone H4 Histone deacetylase 1 Metastasis associated 1 family member 3 PHD finger protein 21A RB binding protein 4, chromatin remodeling factor Transducin beta like 1 X-linked receptor 1	A0A1D5NXL1 A0A1D5PFQ6 A0A1D5PY49 A0A1L1RNY8 A0A3Q2UDI2 E1C0L3 F1NP02 F2Z4M0 P02263 P0C1H3 P0C1H4 P0C1H5 P56517 P62801 P70082 P84229 Q9PSW9 R4GGQ7	GATAD2A H2A-IX H2AFX H2B-I H2B-II H2B-III H2B-IV H2B-V H2B-VI H2B-VII H2B-VIII H3-I H3-II H3-III H3-IV H3-V H3-VI H3-VII H3-VIII H4-I H4-II H4-III H4-IV H4-V H4-VI H4-VII HDAC1 HDAC1A HIST1H2B5L HMG20B LOC426037 MTA3 PHF21A RBBP4 TBL1XR1	Gallus gallus (chicken)
Metal ion SLC transporters	Natural resistance-associated macrophage protein 1 Solute carrier family 40 member Solute carrier family 41 member Solute carrier family 41 member	E1C334 F1NWZ7 P51027 Q5F3K3	NRAMP1 SLC11A1 SLC40A1 SLC41A1 SLC41A2	Gallus gallus (chicken)
Negative regulation of FGFR3 signaling	Fibroblast growth factor 1 Fibroblast growth factor 2 Fibroblast growth factor receptor 3 Fibroblast growth factor receptor substrate 2 Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Growth factor receptor-bound protein 2 Polyubiquitin-B Tyrosine-protein phosphatase non-receptor type 11 Ubiquitin B Ubiquitin-ribosomal protein eS31 fusion protein	A0A1D5P546 A3R0S3 E1BZW7 E1C021 P0CG62 P18460 P19596 P48800 P79781 Q197G3 Q4R0X9 Q90687 Q9I950 R4GIR0	CEK2 FGF-18 FGF1 FGF18 FGF2 FGF23 FGF4 FGF8 FGFR3 FRS2 Fgf16 GRB2 PTPN11 RPS27A UBA80 UBB	Gallus gallus (chicken)
Nicotinate metabolism	ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase NAD(+) kinase Nicotinamide-nucleotide adenylyltransferase Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 2	A0A1D5NZW2 A0A1D5PVT8 A0A1L1RQU5 E1BXJ1 E5G6H7	BST1 CD38 NADK NMNAT1 NMNAT2	Gallus gallus (chicken)
NTF3 activates NTRK3 signaling	NT-3 growth factor receptor Neurotrophin-3	A0A3Q2U804 Q91044	NTF3 NTRK3 TRKC	Gallus gallus (chicken)
Formation of the beta-catenin:TCF transactivating complex	BCL9 transcription coactivator Catenin beta-1 Histone H2A-IV Histone H2A.J Histone H2A.V Histone H2A Histone H2A Histone H2A Histone H2B 1/2/3/4/6 Histone H2B 5 Histone H2B 7 Histone H2B 8 Histone H2B Histone H2B Histone H3.2 Histone H3.3 Histone H4 Histone deacetylase 1 Lymphoid enhancer binding factor 1 Parafibromin Pygopus family PHD finger 1 RB binding protein 5, histone lysine methyltransferase complex subunit RuvB-like helicase TLE family member 1, transcriptional corepressor TLE family member 3, transcriptional corepressor Transcription factor 7 (T-cell specific, HMG-box) Uncharacterized protein	A0A1D5NYE8 A0A1D5P5C3 A0A1D5PQ44 A0A1D5PY49 A0A1L1RNY8 A0A3Q2TTV3 A0A3Q2UDI2 A0A3Q3B1W2 E1BWE1 F1N8Z4 F1NDB6 F1NDD7 F1P5G5 P02263 P02272 P0C1H3 P0C1H4 P0C1H5 P56517 P62801 P70082 P84229 P84247 Q5ZIL1 Q5ZLM0 Q5ZLX3 Q9PSW9	BCL9 CDC73 CTNNB1 H2A-IX H2AF H2AFX H2AZ2 H2B-I H2B-II H2B-III H2B-IV H2B-V H2B-VI H2B-VII H2B-VIII H3-I H3-II H3-III H3-IV H3-IX H3-V H3-VI H3-VII H3-VIII H3-X H4-I H4-II H4-III H4-IV H4-V H4-VI H4-VII HDAC1 HDAC1A HIST1H2B5L LEF1 LOC100859381 LOC426037 PYGO1 RBBP5 RCJMB04_25e24 RUVBL1 TCF7 TLE1 TLE3	Gallus gallus (chicken)
Neurotransmitter receptors and postsynaptic signal transmission	Glycine receptor beta	F1P037	GLRB	Gallus gallus (chicken)
TNFR2 non-canonical NF-kB pathway	26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 2 26S proteasome regulatory subunit 7 AAA+ ATPase domain-containing protein Adhesion regulating molecule 1 B-cell-activating factor BAFF CD40 ligand Proteasome 26S subunit, non-ATPase 12 Proteasome 26S subunit, non-ATPase 14 Proteasome 26S subunit, non-ATPase 7 Proteasome subunit alpha type Proteasome subunit alpha type Proteasome subunit alpha type Proteasome subunit alpha type Proteasome subunit alpha type Proteasome subunit beta Proteasome subunit beta Proteasome subunit beta TNF receptor superfamily member 1B TNF receptor-associated factor	A0A1D5NTD3 A0A1D5PJW4 A0A1D5PTU3 A0A3Q3AAA5 E1BX02 E1C6N0 F1NC02 F1NEQ6 F1NPQ0 F1NR71 P84169 Q5ZIT7 Q5ZJX9 Q5ZLI2 Q5ZMB8 Q6JLB2 Q7ZT63 Q8JHJ4 Q9I8D8 R4GLB3	ADRM1 BAFF CD40L CD40LG PSMA3 PSMA4 PSMA6 PSMA7 PSMB1 PSMB2 PSMB7 PSMC2 PSMD12 PSMD13 PSMD14 PSMD2 PSMD7 RCJMB04_14i9 RCJMB04_23k2 TNFRSF1B TNFSF13B TNFSF5 TRAF3 cpsmb7	Gallus gallus (chicken)
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein	Mannosyltransferase UDP-N-acetylglucosamine transferase subunit ALG13 UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase	A0A1D5PQ50 A0A1L1RT72 F1P077	ALG12 DPAGT1	Gallus gallus (chicken)	G59406KS
N-glycan trimming and elongation in the cis-Golgi				Gallus gallus (chicken)	G58161NS
Metabolism of Angiotensinogen to Angiotensins	Cathepsin D Neprilysin	Q05744 Q67BJ2	CTSD MME	Gallus gallus (chicken)
VxPx cargo-targeting to cilium	ADP-ribosylation factor Exocyst complex component 2 Exocyst complex component 3 Exocyst complex component 7 Exocyst complex component 8 Ras-related protein Rab-11A Ras-related protein Rab-8A Rhodopsin	A0A1D5P0R2 A0A1D5PP34 F1NHD9 F1P2A7 F1P3Y2 Q5F470 Q5ZJN2 Q5ZKR9	ARF4 EXOC2 EXOC3 EXOC7 EXOC8 RAB11A RAB8A RHO	Gallus gallus (chicken)

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