Synthesis of PIPs at the plasma membrane

Summary
Species
Homo sapiens
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
H2OPiPIP3PIP2ATPADPPI4PPI5PPI(3,4)P2PI3PPIPTPN13:PLEKHA1,2:PIP2PTPN13:PLEKHA1,2PLEKHA3,8ARF1:PLEKHA3,8:PI4PPI4PARF1PLEKHA4,(5,6):PI3PPLEKHA4,(5,6)MTMR9MTMR6:MTMR9MTMR6MTMR8:MTMR9MTMR8PI(3,5)P2MTMR2MTMR2 homodimerMTMR2:SBF2 TetramerSBF2 homodimerRUFY1RUFY1_HUMANRUFY1_HUMANp-Y389,400-RUFY1:PI3PPI3Pp-Y389,400-RUFY1:p-Y389,400-RUFY1:RAB4A:GTP:RAB5:GTP:RAB14:GTPRAB4A:GTPRAB5A:GTPRAB14:GTP
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
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International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: April 7, 2025