adult respiratory distress syndrome

Summary
Synonym
  • ARDS
  • Non-cardiogenic pulmonary edema
  • Shock lung
  • acute respiratory distress syndrome
  • adult RDS
Definition
A respiratory failure that results from diffuse injury to the endothelium of the lung (as in sepsis, chest trauma, massive blood transfusion, aspiration of the gastric contents, or pneumonia) and is characterized by pulmonary edema with an abnormally high amount of protein in the edematous fluid and by difficult rapid breathing and hypoxemia.
Super Class
respiratory failure
Disease Ontology
DOID:11394
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
GARD
Related Genes
Displaying entries 1 - 10 of 38 in total
Gene ID Gene Symbol Description Source
12 SERPINA3 serpin family A member 3
177 AGER advanced glycosylation end-product specific receptor
259 AMBP alpha-1-microglobulin/bikunin precursor
718 C3 complement C3
719 C3AR1 complement C3a receptor 1
727 C5 complement C5
728 C5AR1 complement C5a receptor 1
1906 EDN1 endothelin 1
2152 F3 coagulation factor III, tissue factor
3308 HSPA4 heat shock protein family A (Hsp70) member 4
Displaying entries 31 - 36 of 36 in total
Gene ID Gene Symbol Description Source
54409 Ramp2 receptor (calcitonin) activity modifying protein 2
56532 Ripk3 receptor-interacting serine-threonine kinase 3
74069 Serpina3a serine (or cysteine) peptidase inhibitor, clade A, member 3A
238393 Serpina3f serine (or cysteine) peptidase inhibitor, clade A, member 3F
238395 Serpina3j serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3J
271047 Serpina3b serine (or cysteine) peptidase inhibitor, clade A, member 3B
Displaying entries 1 - 10 of 24 in total
Gene ID Gene Symbol Description Source
24232 C3 complement C3
24617 Serpine1 serpin family E member 1
24773 Sftpa1 surfactant protein A1
24787 Sod2 superoxide dismutase 2
24794 Serpina3c serine (or cysteine) proteinase inhibitor, clade A, member 3C
24795 Serpina3n serpin family A member 3N
24816 Tbxa2r thromboxane A2 receptor
24835 Tnf tumor necrosis factor
25008 Lta lymphotoxin alpha
25325 Il10 interleukin 10
Displaying all 2 entries
Gene ID Gene Symbol Description Source
34091 Spn28Dc Serpin 28Dc
39557 Hsp110 Heat shock protein 110
Displaying all 6 entries
Gene ID Gene Symbol Description Source
178672 srp-3 Serpin domain-containing protein
179125 srp-6 Serpin domain-containing protein
179195 srp-7 Serpin domain-containing protein
179991 zmp-4 Hemopexin;Peptidase metallopeptidase domain-containing protein
180351 W01F3.2 Uncharacterized protein
180836 W01C8.5 DM13 domain-containing protein

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: December 9, 2024