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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
osteoporosis
Summary
- Definition
- A bone resorption disease characterized by decreased density of normally mineralized bone which results_in the thinning of bone tissue and decreased mechanical strength.
- Super Class
- bone resorption disease
External Links
- Disease Ontology
- DOID:11476
- Mondo Disease Ontology
- MeSH
- UMLS
- NCI Thesaurus
- OMIM
Related Genes
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 3552 | IL1A | interleukin 1 alpha | |
| 3557 | IL1RN | interleukin 1 receptor antagonist | |
| 3667 | IRS1 | insulin receptor substrate 1 | |
| 3952 | LEP | leptin | |
| 3953 | LEPR | leptin receptor | |
| 4041 | LRP5 | LDL receptor related protein 5 | |
| 4261 | CIITA | class II major histocompatibility complex transactivator | |
| 4318 | MMP9 | matrix metallopeptidase 9 | |
| 4609 | MYC | MYC proto-oncogene, bHLH transcription factor | |
| 4982 | TNFRSF11B | TNF receptor superfamily member 11b |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 16846 | Lep | leptin | |
| 16847 | Lepr | leptin receptor | |
| 16973 | Lrp5 | low density lipoprotein receptor-related protein 5 | |
| 17395 | Mmp9 | matrix metallopeptidase 9 | |
| 17869 | Myc | myelocytomatosis oncogene | |
| 18383 | Tnfrsf11b | tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin) | |
| 18538 | Pcna | proliferating cell nuclear antigen | |
| 19219 | Ptger4 | prostaglandin E receptor 4 (subtype EP4) | |
| 20656 | Sod2 | superoxide dismutase 2, mitochondrial | |
| 21803 | Tgfb1 | transforming growth factor, beta 1 |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 60628 | Cxcr4 | C-X-C motif chemokine receptor 4 | |
| 81687 | Mmp9 | matrix metallopeptidase 9 | |
| 84023 | Ptger4 | prostaglandin E receptor 4 | |
| 84352 | Col1a2 | collagen type I alpha 2 chain | |
| 116506 | Calcr | calcitonin receptor | |
| 117516 | Tnfsf11 | TNF superfamily member 11 | |
| 156767 | Tnfrsf1b | TNF receptor superfamily member 1B |
| Gene ID | Gene Symbol | Description | Source | Organism |
|---|---|---|---|---|
| 380373 | cxcr4.S | C-X-C motif chemokine receptor 4 S homeolog | Xenopus laevis (African clawed frog) | |
| 397873 | bmp2.L | bone morphogenetic protein 2 L homeolog | Xenopus laevis (African clawed frog) | |
| 398022 | igf1r.S | insulin like growth factor 1 receptor S homeolog | Xenopus laevis (African clawed frog) | |
| 100038176 | cxcr4 | C-X-C motif chemokine receptor 4 | Xenopus tropicalis (tropical clawed frog) | |
| 100144634 | ace | angiotensin I converting enzyme | Xenopus tropicalis (tropical clawed frog) | |
| 100192360 | cxcr4.L | C-X-C motif chemokine receptor 4 L homeolog | Xenopus laevis (African clawed frog) |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 175410 | daf-2 | Insulin-like receptor subunit beta;Protein kinase domain-containing protein;receptor protein-tyrosine kinase | |
| 175942 | pdfr-1 | Calcitonin receptor-like protein 1 | |
| 179068 | dbl-1 | Protein dbl-1 | |
| 179991 | zmp-4 | Hemopexin;Peptidase metallopeptidase domain-containing protein | |
| 180351 | W01F3.2 | Uncharacterized protein | |
| 180780 | acn-1 | Inactive angiotensin-converting enzyme-related protein |
