Sjogren's syndrome

Summary
Synonym
  • Sicca syndrome
  • Sjogren syndrome
  • xerodermosteosis
Definition
An autoimmune disease that involves attack of immune cells which destroy the exocrine glands that produce tears and saliva.
Super Class
autoimmune disease of exocrine system
Disease Ontology
DOID:12894
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
OMIM
GARD
Related Genes
Displaying entries 21 - 30 of 46 in total
Gene ID Gene Symbol Description Source
3558 IL2 interleukin 2
3559 IL2RA interleukin 2 receptor subunit alpha
3565 IL4 interleukin 4
3569 IL6 interleukin 6
3586 IL10 interleukin 10
3596 IL13 interleukin 13
4049 LTA lymphotoxin alpha
4314 MMP3 matrix metallopeptidase 3
4318 MMP9 matrix metallopeptidase 9
4586 MUC5AC mucin 5AC, oligomeric mucus/gel-forming
Displaying entries 21 - 30 of 37 in total
Gene ID Gene Symbol Description Source
17395 Mmp9 matrix metallopeptidase 9
17833 Muc5ac mucin 5, subtypes A and C, tracheobronchial/gastric
18039 Nefl neurofilament, light polypeptide
18979 Pon1 paraoxonase 1
19143 St14 suppression of tumorigenicity 14 (colon carcinoma)
19692 Reg1 regenerating islet-derived 1
20344 Selp selectin, platelet
21803 Tgfb1 transforming growth factor, beta 1
21825 Thbs1 thrombospondin 1
21926 Tnf tumor necrosis factor
Displaying entries 11 - 20 of 25 in total
Gene ID Gene Symbol Description Source
25704 Il2ra interleukin 2 receptor subunit alpha
25712 Ifng interferon gamma
59086 Tgfb1 transforming growth factor, beta 1
60582 Il1rn interleukin 1 receptor antagonist
81687 Mmp9 matrix metallopeptidase 9
81818 Vim vimentin
83613 Nefl neurofilament light chain
84024 Pon1 paraoxonase 1
84349 Cd40lg CD40 ligand
116553 Il13 interleukin 13
Displaying 1 entry
Gene ID Gene Symbol Description Source
447803 pon1 paraoxonase 1
Displaying all 2 entries
Gene ID Gene Symbol Description Source Organism
448598 pon2 paraoxonase 2 Xenopus tropicalis (tropical clawed frog)
779087 gdnf.L glial cell derived neurotrophic factor L homeolog Xenopus laevis (African clawed frog)
Displaying all 6 entries
Gene ID Gene Symbol Description Source
171999 poml-2 Arylesterase
178748 zmp-3 Matrix metalloproteinase-C
179991 zmp-4 Hemopexin;Peptidase metallopeptidase domain-containing protein
180351 W01F3.2 Uncharacterized protein
187297 poml-1 PON (paraoxonase) and MEC-6 Like
188252 lev-9 Protein lev-9

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Last updated: December 9, 2024