major depressive disorder

Summary
Synonym
  • clinical depression
  • major depression
  • recurrent major depression
  • single major depressive episode
  • unipolar depression
Definition
A depressive disorder that is characterized by at least two weeks of loss of interest or pleasure in normally enjoyable activities or depressed mood along with additional cognitive or somatic impairments such as appetite or weight changes, sleep difficulties, psychomotor agitation or retardation, fatigue or loss of energy, diminished ability to think or concentrate, feelings of worthlessness or excessive guilt, and suicidality.
Super Class
depressive disorder
External Links
Disease Ontology
DOID:1470
Mondo Disease Ontology
UMLS
NCI Thesaurus
OMIM
MGI genotype (from TogoID)
WikiPathways (from TogoID)
Related Genes
Displaying entries 91 - 100 of 217 in total
Gene ID Gene Symbol Description Source
4199 ME1 malic enzyme 1
4350 MPG N-methylpurine DNA glycosylase
4595 MUTYH mutY DNA glycosylase
4684 NCAM1 neural cell adhesion molecule 1
4907 NT5E 5'-nucleotidase ecto
4952 OCRL OCRL inositol polyphosphate-5-phosphatase
4968 OGG1 8-oxoguanine DNA glycosylase
4978 OPCML opioid binding protein/cell adhesion molecule like
5048 PAFAH1B1 platelet activating factor acetylhydrolase 1b regulatory subunit 1
5067 CNTN3 contactin 3
Displaying 1 entry
Gene ID Gene Symbol Description Source
15558 Htr2a 5-hydroxytryptamine (serotonin) receptor 2A
Displaying 1 entry
Gene ID Gene Symbol Description Source
29595 Htr2a 5-hydroxytryptamine receptor 2A

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Last updated: August 19, 2024