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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
major depressive disorder
Summary
- Synonym
-
- clinical depression
- major depression
- recurrent major depression
- single major depressive episode
- unipolar depression
- Definition
- A depressive disorder that is characterized by at least two weeks of loss of interest or pleasure in normally enjoyable activities or depressed mood along with additional cognitive or somatic impairments such as appetite or weight changes, sleep difficulties, psychomotor agitation or retardation, fatigue or loss of energy, diminished ability to think or concentrate, feelings of worthlessness or excessive guilt, and suicidality.
- Super Class
- depressive disorder
External Links
- Disease Ontology
- DOID:1470
- Mondo Disease Ontology
- UMLS
- NCI Thesaurus
- OMIM
- MGI genotype (from TogoID)
- WikiPathways (from TogoID)
Related Genes
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 10858 | CYP46A1 | cytochrome P450 family 46 subfamily A member 1 | |
| 10908 | PNPLA6 | patatin like phospholipase domain containing 6 | |
| 11253 | MAN1B1 | mannosidase alpha class 1B member 1 | |
| 11282 | MGAT4B | alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B | |
| 11332 | ACOT7 | acyl-CoA thioesterase 7 | |
| 22901 | ARSG | arylsulfatase G | |
| 22933 | SIRT2 | sirtuin 2 | |
| 23236 | PLCB1 | phospholipase C beta 1 | |
| 23483 | TGDS | TDP-glucose 4,6-dehydratase | |
| 23583 | SMUG1 | single-strand-selective monofunctional uracil-DNA glycosylase 1 |
Related Glycoprotein
| UniProt ID | Protein Name | Source |
|---|---|---|
| P00325 | All-trans-retinol dehydrogenase [NAD(+)] ADH1B | |
| P00326 | Alcohol dehydrogenase 1C | |
| P00338 | L-lactate dehydrogenase A chain | |
| P04040 | Catalase | |
| P04062 | Lysosomal acid glucosylceramidase | |
| P04156 | Major prion protein | |
| P05091 | Aldehyde dehydrogenase, mitochondrial | |
| P05093 | Steroid 17-alpha-hydroxylase/17,20 lyase | |
| P05177 | Cytochrome P450 1A2 | |
| P05186 | Alkaline phosphatase, tissue-nonspecific isozyme |
