tropical spastic paraparesis

Summary
Synonym
  • HTLV-associated myelopathy
  • Tropical spastic paralysis
  • Tropical spastic paraplegia
Definition
A viral infectious disease that results in inflammation located in spinal cord, has_material_basis_in Human T-lymphotropic virus 1, which is transmitted by sexual contact, and transmitted by breast feeding. The infection has symptom spastic weakness of both legs, has symptom muscle stiffness, has symptom sensory disturbance, and has symptom spasms.
Super Class
spinal cord disease viral infectious disease
Disease Ontology
DOID:321
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
OMIM
MGI genotype (from TogoID)
Related Genes
Displaying entries 1 - 10 of 11 in total
Gene ID Gene Symbol Description Source
718 C3 complement C3
1493 CTLA4 cytotoxic T-lymphocyte associated protein 4
3119 HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
3178 HNRNPA1 heterogeneous nuclear ribonucleoprotein A1
4313 MMP2 matrix metallopeptidase 2
4790 NFKB1 nuclear factor kappa B subunit 1
6935 ZEB1 zinc finger E-box binding homeobox 1
8784 TNFRSF18 TNF receptor superfamily member 18
22914 KLRK1 killer cell lectin like receptor K1
59067 IL21 interleukin 21
Displaying entries 11 - 12 of 12 in total
Gene ID Gene Symbol Description Source
246779 Il27 interleukin 27
330496 Ifnl2 interferon lambda 2
Displaying all 4 entries
Gene ID Gene Symbol Description Source
24232 C3 complement C3
24934 Klrk1 killer cell lectin like receptor K1
81686 Mmp2 matrix metallopeptidase 2
365769 Il21 interleukin 21
Displaying all 2 entries
Gene ID Gene Symbol Description Source
179991 zmp-4 Hemopexin;Peptidase metallopeptidase domain-containing protein
180351 W01F3.2 Uncharacterized protein

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: December 9, 2024