human immunodeficiency virus infectious disease

Summary
Synonym
  • HIV infection
Definition
A viral infectious disease that results in destruction of immune system, leading to life-threatening opportunistic infections and cancers, has_material_basis_in Human immunodeficiency virus 1 or has_material_basis_in Human immunodeficiency virus 2, which are transmitted by sexual contact, transmitted by transfer of blood, semen, vaginal fluid, pre-ejaculate, or breast milk, transmitted by congenital method, and transmitted by contaminated needles. The virus infects helper T cells (CD4+ T cells) which are directly or indirectly destroyed, macrophages, and dendritic cells. The infection has symptom diarrhea, has symptom fatigue, has symptom fever, has symptom vaginal yeast infection, has symptom headache, has symptom mouth sores, has symptom muscle aches, has symptom sore throat, and has symptom swollen lymph glands.
Super Class
viral infectious disease
Disease Ontology
DOID:526
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
WikiPathways (from TogoID)
Related Genes
Displaying entries 41 - 50 of 56 in total
Gene ID Gene Symbol Description Source
6347 CCL2 C-C motif chemokine ligand 2
6352 CCL5 C-C motif chemokine ligand 5
6356 CCL11 C-C motif chemokine ligand 11
6403 SELP selectin P
7098 TLR3 toll like receptor 3
7124 TNF tumor necrosis factor
9021 SOCS3 suppressor of cytokine signaling 3
9332 CD163 CD163 molecule
29126 CD274 CD274 molecule
30835 CD209 CD209 molecule
Displaying entries 31 - 40 of 62 in total
Gene ID Gene Symbol Description Source
18671 Abcb1a ATP-binding cassette, sub-family B member 1A
18793 Plaur plasminogen activator, urokinase receptor
19225 Ptgs2 prostaglandin-endoperoxide synthase 2
20292 Ccl11 C-C motif chemokine ligand 11
20296 Ccl2 C-C motif chemokine ligand 2
20344 Selp selectin, platelet
20700 Serpina1a serine (or cysteine) peptidase inhibitor, clade A, member 1A
20701 Serpina1b serine (or cysteine) preptidase inhibitor, clade A, member 1B
20702 Serpina1c serine (or cysteine) peptidase inhibitor, clade A, member 1C
20703 Serpina1d serine (or cysteine) peptidase inhibitor, clade A, member 1D
Displaying entries 21 - 25 of 25 in total
Gene ID Gene Symbol Description Source
246097 Fas Fas cell surface death receptor
304966 Fcgr3a Fc gamma receptor 3A
353253 Kir3dl1 killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 1
365769 Il21 interleukin 21
100360977 Ppial4d peptidylprolyl isomerase A (cyclophilin A)-like 4D
Displaying all 4 entries
Gene ID Gene Symbol Description Source
34091 Spn28Dc Serpin 28Dc
36016 Sting sting
36428 Mdr49 Multi drug resistance 49
38726 Mdr65 Multi drug resistance 65
Displaying all 4 entries
Gene ID Gene Symbol Description Source
173794 vab-1 Ephrin receptor 1
178215 pgp-1 Multidrug resistance protein pgp-1
181326 pgp-3 Multidrug resistance protein pgp-3
188252 lev-9 Protein lev-9
Displaying all 2 entries
Gene ID Gene Symbol Description Source
851665 RLI1 Fe-S cluster-binding ribosome biosynthesis protein
853671 STE6 ATP-binding cassette a-factor transporter STE6

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Last updated: December 9, 2024