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human immunodeficiency virus infectious disease
Summary
- Synonym
-
- HIV infection
- Definition
- A viral infectious disease that results in destruction of immune system, leading to life-threatening opportunistic infections and cancers, has_material_basis_in Human immunodeficiency virus 1 or has_material_basis_in Human immunodeficiency virus 2, which are transmitted by sexual contact, transmitted by transfer of blood, semen, vaginal fluid, pre-ejaculate, or breast milk, transmitted by congenital method, and transmitted by contaminated needles. The virus infects helper T cells (CD4+ T cells) which are directly or indirectly destroyed, macrophages, and dendritic cells. The infection has symptom diarrhea, has symptom fatigue, has symptom fever, has symptom vaginal yeast infection, has symptom headache, has symptom mouth sores, has symptom muscle aches, has symptom sore throat, and has symptom swollen lymph glands.
- Super Class
- viral infectious disease
Related Genes
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 4360 | MRC1 | mannose receptor C-type 1 | |
| 4968 | OGG1 | 8-oxoguanine DNA glycosylase | |
| 5290 | PIK3CA | phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha | |
| 5320 | PLA2G2A | phospholipase A2 group IIA | |
| 5329 | PLAUR | plasminogen activator, urokinase receptor | |
| 5476 | CTSA | cathepsin A | |
| 5563 | PRKAA2 | protein kinase AMP-activated catalytic subunit alpha 2 | |
| 5621 | PRNP | prion protein (Kanno blood group) | |
| 5660 | PSAP | prosaposin | |
| 5728 | PTEN | phosphatase and tensin homolog |
Related Glycoprotein
| UniProt ID | Protein Name | Source |
|---|---|---|
| P16109 | P-selectin | |
| P16278 | Beta-galactosidase | |
| P16442 | Histo-blood group ABO system transferase | |
| P16581 | E-selectin | |
| P18827 | Syndecan-1 | |
| P19320 | Vascular cell adhesion protein 1 | |
| P19526 | Galactoside alpha-(1,2)-fucosyltransferase 1 | |
| P21964 | Catechol O-methyltransferase | |
| P22309 | UDP-glucuronosyltransferase 1A1 | |
| P22897 | Macrophage mannose receptor 1 |
