human immunodeficiency virus infectious disease

Summary
Synonym
  • HIV infection
Definition
A viral infectious disease that results in destruction of immune system, leading to life-threatening opportunistic infections and cancers, has_material_basis_in Human immunodeficiency virus 1 or has_material_basis_in Human immunodeficiency virus 2, which are transmitted by sexual contact, transmitted by transfer of blood, semen, vaginal fluid, pre-ejaculate, or breast milk, transmitted by congenital method, and transmitted by contaminated needles. The virus infects helper T cells (CD4+ T cells) which are directly or indirectly destroyed, macrophages, and dendritic cells. The infection has symptom diarrhea, has symptom fatigue, has symptom fever, has symptom vaginal yeast infection, has symptom headache, has symptom mouth sores, has symptom muscle aches, has symptom sore throat, and has symptom swollen lymph glands.
Super Class
viral infectious disease
Disease Ontology
DOID:526
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
WikiPathways (from TogoID)
Related Genes
Displaying entries 51 - 56 of 56 in total
Gene ID Gene Symbol Description Source
50615 IL21R interleukin 21 receptor
54210 TREM1 triggering receptor expressed on myeloid cells 1
55904 KMT2E lysine methyltransferase 2E (inactive)
59067 IL21 interleukin 21
340061 STING1 stimulator of interferon response cGAMP interactor 1
729230 CCR2 C-C motif chemokine receptor 2
Displaying entries 51 - 60 of 62 in total
Gene ID Gene Symbol Description Source
69188 Kmt2e lysine (K)-specific methyltransferase 2E
93671 Cd163 CD163 antigen
110557 H2-Q6 histocompatibility 2, Q region locus 6
142980 Tlr3 toll-like receptor 3
170776 Cd209c CD209c antigen
170779 Cd209d CD209d antigen
170786 Cd209a CD209a antigen
227288 Cxcr1 C-X-C motif chemokine receptor 1
246256 Fcgr4 Fc receptor, IgG, low affinity IV
246779 Il27 interleukin 27
Displaying entries 21 - 25 of 25 in total
Gene ID Gene Symbol Description Source
246097 Fas Fas cell surface death receptor
304966 Fcgr3a Fc gamma receptor 3A
353253 Kir3dl1 killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 1
365769 Il21 interleukin 21
100360977 Ppial4d peptidylprolyl isomerase A (cyclophilin A)-like 4D
Displaying all 4 entries
Gene ID Gene Symbol Description Source
34091 Spn28Dc Serpin 28Dc
36016 Sting sting
36428 Mdr49 Multi drug resistance 49
38726 Mdr65 Multi drug resistance 65
Displaying all 4 entries
Gene ID Gene Symbol Description Source
173794 vab-1 Ephrin receptor 1
178215 pgp-1 Multidrug resistance protein pgp-1
181326 pgp-3 Multidrug resistance protein pgp-3
188252 lev-9 Protein lev-9
Displaying all 2 entries
Gene ID Gene Symbol Description Source
851665 RLI1 Fe-S cluster-binding ribosome biosynthesis protein
853671 STE6 ATP-binding cassette a-factor transporter STE6

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Last updated: December 9, 2024