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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
lung disease
Summary
- Definition
- A lower respiratory tract disease in which the function of the lungs is adversely affected by narrowing or blockage of the airways resulting in poor air flow, a loss of elasticity in the lungs that produces a decrease in the total volume of air that the lungs are able to hold, and clotting, scarring, or inflammation of the blood vessels that affect the ability of the lungs to take up oxygen and to release carbon dioxide.
- Super Class
- lower respiratory tract disease
External Links
- Disease Ontology
- DOID:850
- Mondo Disease Ontology
- MeSH
- UMLS
- NCI Thesaurus
Related Genes
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 4353 | MPO | myeloperoxidase | |
| 4582 | MUC1 | mucin 1, cell surface associated | |
| 4843 | NOS2 | nitric oxide synthase 2 | |
| 4846 | NOS3 | nitric oxide synthase 3 | |
| 5054 | SERPINE1 | serpin family E member 1 | |
| 6347 | CCL2 | C-C motif chemokine ligand 2 | |
| 6352 | CCL5 | C-C motif chemokine ligand 5 | |
| 6376 | CX3CL1 | C-X3-C motif chemokine ligand 1 | |
| 6439 | SFTPB | surfactant protein B | |
| 6440 | SFTPC | surfactant protein C |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 11421 | Ace | angiotensin I converting enzyme | |
| 11539 | Adora1 | adenosine A1 receptor | |
| 11540 | Adora2a | adenosine A2a receptor | |
| 12062 | Bdkrb2 | bradykinin receptor, beta 2 | |
| 12267 | C3ar1 | complement component 3a receptor 1 | |
| 12273 | C5ar1 | complement component 5a receptor 1 | |
| 12638 | Cftr | cystic fibrosis transmembrane conductance regulator | |
| 12832 | Col5a2 | collagen, type V, alpha 2 | |
| 12985 | Csf3 | colony stimulating factor 3 (granulocyte) | |
| 13617 | Ednra | endothelin receptor type A |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 25325 | Il10 | interleukin 10 | |
| 25350 | Sftpd | surfactant protein D | |
| 25356 | Cntn2 | contactin 2 | |
| 25369 | Adora2a | adenosine A2a receptor | |
| 25670 | Il15 | interleukin 15 | |
| 25712 | Ifng | interferon gamma | |
| 29260 | Tlr4 | toll-like receptor 4 | |
| 29290 | Adora1 | adenosine A1 receptor | |
| 59086 | Tgfb1 | transforming growth factor, beta 1 | |
| 81687 | Mmp9 | matrix metallopeptidase 9 |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 173828 | rig-6 | Contactin rig-6 | |
| 174462 | let-23 | Receptor tyrosine-protein kinase let-23;receptor protein-tyrosine kinase | |
| 175383 | zmp-2 | Matrix metalloproteinase-B | |
| 178672 | srp-3 | Serpin domain-containing protein | |
| 179991 | zmp-4 | Hemopexin;Peptidase metallopeptidase domain-containing protein | |
| 180351 | W01F3.2 | Uncharacterized protein | |
| 180780 | acn-1 | Inactive angiotensin-converting enzyme-related protein | |
| 180841 | gnrr-4 | G-protein coupled receptors family 1 profile domain-containing protein | |
| 181178 | gpx-5 | Glutathione peroxidase | |
| 181288 | pxn-2 | Peroxidasin homolog pxn-2 |
