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Standards Ontologies Notations
colorectal cancer

Summary
Definition
A large intestine cancer that is located_in the colon and/or located_in the rectum.
Super Class
large intestine cancer
Disease Ontology
DOID:9256
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
OMIM
MGI genotype (from TogoID)
WikiPathways (from TogoID)
Related Genes
Displaying entries 141 - 150 of 174 in total
Gene ID Gene Symbol Description Source
10413 YAP1 Yes1 associated transcriptional regulator
10592 SMC2 structural maintenance of chromosomes 2
10801 SEPTIN9 septin 9
10863 ADAM28 ADAM metallopeptidase domain 28
11016 ATF7 activating transcription factor 7
11122 PTPRT protein tyrosine phosphatase receptor type T
11200 CHEK2 checkpoint kinase 2
23405 DICER1 dicer 1, ribonuclease III
25805 BAMBI BMP and activin membrane bound inhibitor
26524 LATS2 large tumor suppressor kinase 2
Displaying entries 31 - 40 of 125 in total
Gene ID Gene Symbol Description Source
14629 Gclc glutamate-cysteine ligase, catalytic subunit
14775 Gpx1 glutathione peroxidase 1
14811 Grin2a glutamate receptor, ionotropic, NMDA2A (epsilon 1)
14961 H2-Ab1 histocompatibility 2, class II antigen A, beta 1
15216 Hfe homeostatic iron regulator
15275 Hk1 hexokinase 1
15387 Hnrnpk heterogeneous nuclear ribonucleoprotein K
15481 Hspa8 heat shock protein 8
16542 Kdr kinase insert domain protein receptor
16653 Kras Kirsten rat sarcoma viral oncogene homolog
Displaying entries 31 - 40 of 44 in total
Gene ID Gene Symbol Description Source
81687 Mmp9 matrix metallopeptidase 9
81809 Tgfb2 transforming growth factor, beta 2
83619 Nfe2l2 NFE2 like bZIP transcription factor 2
83785 Vegfa vascular endothelial growth factor A
83837 Bambi BMP and activin membrane-bound inhibitor
84353 Ctnnb1 catenin beta 1
113902 Ces1d carboxylesterase 1D
170911 Pik3ca phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
260320 F7 coagulation factor VII
290771 Pdgfrl platelet-derived growth factor receptor-like
Displaying entries 1 - 10 of 18 in total
Gene ID Gene Symbol Description Source
31293 N Notch
31792 Nrg Neuroglian
32556 Stim Stromal interaction molecule
33196 smo smoothened
33496 lilli lilliputian
34091 Spn28Dc Serpin 28Dc
35560 Bap170 Brahma associated protein 170kD
37455 Egfr Epidermal growth factor receptor
39392 Est-6 Esterase 6
39393 Est-P Esterase P
Displaying all 8 entries
Gene ID Gene Symbol Description Source
30225 smo smoothened, frizzled class receptor
30682 vegfaa vascular endothelial growth factor Aa
30718 notch1a notch receptor 1a
406411 rhoaa ras homolog gene family, member Aa
406659 rhoac ras homolog gene family, member Ac
554230 kdr kinase insert domain receptor (a type III receptor tyrosine kinase)
559736 galnt12 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 12
100006041 rhoab ras homolog gene family, member Ab
Displaying entries 1 - 10 of 16 in total
Gene ID Gene Symbol Description Source Organism
373801 tgfb2.L transforming growth factor beta 2 L homeolog Xenopus laevis (African clawed frog)
379783 akt2.L v-akt murine thymoma viral oncogene homolog 2 L homeolog Xenopus laevis (African clawed frog)
380373 cxcr4.S C-X-C motif chemokine receptor 4 S homeolog Xenopus laevis (African clawed frog)
397778 tgfb1.L transforming growth factor beta 1 L homeolog Xenopus laevis (African clawed frog)
397787 ttr.L transthyretin L homeolog Xenopus laevis (African clawed frog)
399170 akt1.S AKT serine/threonine kinase 1 S homeolog Xenopus laevis (African clawed frog)
399187 adam10.S ADAM metallopeptidase domain 10 S homeolog Xenopus laevis (African clawed frog)
399347 fgfr3.S fibroblast growth factor receptor 3 (achondroplasia, thanatophoric dwarfism) S homeolog Xenopus laevis (African clawed frog)
432172 akt2.S v-akt murine thymoma viral oncogene homolog 2 S homeolog Xenopus laevis (African clawed frog)
100037842 notch1 notch 1 receptor Xenopus tropicalis (tropical clawed frog)
Displaying entries 1 - 10 of 27 in total
Gene ID Gene Symbol Description Source
172233 unc-40 Netrin receptor unc-40
172689 sup-17 Disintegrin and metalloproteinase domain-containing protein 10 homolog
174044 sma-6 Serine/threonine-protein kinase receptor sma-6
174462 let-23 Receptor tyrosine-protein kinase let-23;receptor protein-tyrosine kinase
175182 ver-1 Protein ver-1
175201 stim-1 Stromal interaction molecule 1
175590 cdh-4 Cadherin-4
176282 lin-12 lin-12/Notch intracellular domain
176286 glp-1 glp-1/Notch intracellular domain
176575 plr-1 putative E3 ubiquitin-protein ligase plr-1
Displaying entries 1 - 10 of 12 in total
Gene ID Gene Symbol Description Source
850438 ERS1 cystinosin-like protein ERS1
850614 HXK1 hexokinase 1
851543 OSH2 oxysterol-binding protein related protein OSH2
851670 GIS1 histone demethylase GIS1
852410 CYC8 transcription regulator CYC8
852546 GPX2 glutathione peroxidase GPX2
853313 PBS2 mitogen-activated protein kinase kinase PBS2
853361 ALY2 Aly2p
853770 BUD2 GTPase-activating protein BUD2
853842 GPX1 glutathione peroxidase GPX1
The Human Phenotype Ontology
Displaying all 7 entries
HPO ID HPO Term
HP:0000006 Autosomal dominant inheritance
HP:0006716 Hereditary nonpolyposis colorectal carcinoma
HP:0002891 Uterine leiomyosarcoma
HP:0006753 Neoplasm of the stomach
HP:0001442 Typified by somatic mosaicism
HP:0006740 Transitional cell carcinoma of the bladder
HP:0005584 Renal cell carcinoma
Displaying all 3 entries
Gene ID Gene Symbol Description
4893 NRAS NRAS proto-oncogene, GTPase
5290 PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
5320 PLA2G2A phospholipase A2 group IIA
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 9, 2024