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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
steatotic liver disease
Summary
- Synonym
-
- Fatty change of liver
- SLD
- Steatosis of liver
- alcoholic fatty liver
- fatty liver disease
- hepatic lipidosis
- hepatic steatosis
- Definition
- A lipid storage disease characterized by the accumulation of large vacuoles of triglyceride fat in at least 5% of hepatocytes.
- Super Class
- lipid storage disease liver disease
External Links
- Disease Ontology
- DOID:9452
- Mondo Disease Ontology
- MeSH
- UMLS
- OMIM
- MGI genotype (from TogoID)
- WikiPathways (from TogoID)
Related Genes
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 2876 | GPX1 | glutathione peroxidase 1 | |
| 3030 | HADHA | hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha | |
| 3032 | HADHB | hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta | |
| 3077 | HFE | homeostatic iron regulator | |
| 3309 | HSPA5 | heat shock protein family A (Hsp70) member 5 | |
| 3356 | HTR2A | 5-hydroxytryptamine receptor 2A | |
| 3357 | HTR2B | 5-hydroxytryptamine receptor 2B | |
| 3569 | IL6 | interleukin 6 | |
| 3586 | IL10 | interleukin 10 | |
| 3598 | IL13RA2 | interleukin 13 receptor subunit alpha 2 |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 11303 | Abca1 | ATP-binding cassette, sub-family A member 1 | |
| 11450 | Adipoq | adiponectin, C1Q and collagen domain containing | |
| 11555 | Adrb2 | adrenergic receptor, beta 2 | |
| 11615 | Ahcyl | adenosylhomocysteinase like | |
| 11647 | Alpl | alkaline phosphatase, liver/bone/kidney | |
| 12780 | Abcc2 | ATP-binding cassette, sub-family member 2 | |
| 12876 | Cpe | carboxypeptidase E | |
| 13030 | Ctsb | cathepsin B | |
| 14182 | Fgfr1 | fibroblast growth factor receptor 1 | |
| 14377 | G6pc1 | glucose-6-phosphatase catalytic subunit 1 |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 24385 | Gck | glucokinase | |
| 24505 | Ins1 | insulin 1 | |
| 24506 | Ins2 | insulin 2 | |
| 25303 | Abcc2 | ATP binding cassette subfamily C member 2 | |
| 25325 | Il10 | interleukin 10 | |
| 25586 | Alpl | alkaline phosphatase, biomineralization associated | |
| 25608 | Lep | leptin | |
| 25634 | G6pc1 | glucose-6-phosphatase catalytic subunit 1 | |
| 25635 | Mc4r | melanocortin 4 receptor | |
| 25664 | Pparg | peroxisome proliferator-activated receptor gamma |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 35362 | Mtp | Microsomal triacylglycerol transfer protein | |
| 37028 | ACOX1 | acyl-CoA oxidase 1 | |
| 39954 | Oatp74D | Organic anion transporting polypeptide 74D | |
| 41549 | Octbeta2R | Octopamine beta2 receptor | |
| 42160 | htl | heartless | |
| 42549 | InR | Insulin-like receptor | |
| 43191 | Hex-t2 | Hexokinase testis 2 | |
| 117364 | Hex-t1 | Hexokinase testis 1 |
| Gene ID | Gene Symbol | Description | Source | Organism |
|---|---|---|---|---|
| 378695 | ins.L | insulin L homeolog | Xenopus laevis (African clawed frog) | |
| 378696 | ins.S | insulin S homeolog | Xenopus laevis (African clawed frog) | |
| 395003 | dgat2 | diacylglycerol O-acyltransferase 2 | Xenopus tropicalis (tropical clawed frog) | |
| 397782 | fgfr1.S | fibroblast growth factor receptor 1 S homeolog | Xenopus laevis (African clawed frog) | |
| 399444 | fgfr1.L | fibroblast growth factor receptor 1 L homeolog | Xenopus laevis (African clawed frog) | |
| 548648 | fgfr1 | fibroblast growth factor receptor 1 | Xenopus tropicalis (tropical clawed frog) |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 180408 | mrp-2 | Multidrug resistance-associated protein 1 | |
| 180409 | mrp-1 | Multidrug resistance-associated protein 1 | |
| 180931 | cpr-6 | Cathepsin B-like cysteine proteinase 6 | |
| 181145 | F47E1.2 | Solute carrier organic anion transporter family member | |
| 181178 | gpx-5 | Glutathione peroxidase | |
| 181684 | cpd-2 | Peptidase M14 carboxypeptidase A domain-containing protein | |
| 182513 | gpx-3 | Glutathione peroxidase 3 |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 850317 | GLK1 | glucokinase | |
| 850614 | HXK1 | hexokinase 1 | |
| 850645 | BPT1 | ATP-binding cassette bilirubin transporter BPT1 | |
| 851006 | ECM38 | gamma-glutamyltransferase | |
| 852092 | PHO8 | alkaline phosphatase PHO8 | |
| 852128 | EMI2 | putative glucokinase | |
| 852639 | HXK2 | hexokinase 2 | |
| 852667 | POX1 | acyl-CoA oxidase | |
| 853418 | KAR2 | Hsp70 family ATPase KAR2 | |
| 854419 | DGA1 | diacylglycerol O-acyltransferase |
