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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
steatotic liver disease
Summary
- Synonym
-
- Fatty change of liver
- SLD
- Steatosis of liver
- alcoholic fatty liver
- fatty liver disease
- hepatic lipidosis
- hepatic steatosis
- Definition
- A lipid storage disease characterized by the accumulation of large vacuoles of triglyceride fat in at least 5% of hepatocytes.
- Super Class
- lipid storage disease liver disease
External Links
- Disease Ontology
- DOID:9452
- Mondo Disease Ontology
- MeSH
- UMLS
- OMIM
- MGI genotype (from TogoID)
- WikiPathways (from TogoID)
Related Genes
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 2876 | GPX1 | glutathione peroxidase 1 | |
| 3030 | HADHA | hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha | |
| 3032 | HADHB | hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta | |
| 3077 | HFE | homeostatic iron regulator | |
| 3309 | HSPA5 | heat shock protein family A (Hsp70) member 5 | |
| 3356 | HTR2A | 5-hydroxytryptamine receptor 2A | |
| 3357 | HTR2B | 5-hydroxytryptamine receptor 2B | |
| 3569 | IL6 | interleukin 6 | |
| 3586 | IL10 | interleukin 10 | |
| 3598 | IL13RA2 | interleukin 13 receptor subunit alpha 2 |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 11303 | Abca1 | ATP-binding cassette, sub-family A member 1 | |
| 11450 | Adipoq | adiponectin, C1Q and collagen domain containing | |
| 11555 | Adrb2 | adrenergic receptor, beta 2 | |
| 11615 | Ahcyl | adenosylhomocysteinase like | |
| 11647 | Alpl | alkaline phosphatase, liver/bone/kidney | |
| 12780 | Abcc2 | ATP-binding cassette, sub-family member 2 | |
| 12876 | Cpe | carboxypeptidase E | |
| 13030 | Ctsb | cathepsin B | |
| 14182 | Fgfr1 | fibroblast growth factor receptor 1 | |
| 14377 | G6pc1 | glucose-6-phosphatase catalytic subunit 1 |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 25669 | Cpe | carboxypeptidase E | |
| 25747 | Ppara | peroxisome proliferator activated receptor alpha | |
| 29527 | Ptgs2 | prostaglandin-endoperoxide synthase 2 | |
| 29581 | Htr2b | 5-hydroxytryptamine receptor 2B | |
| 29595 | Htr2a | 5-hydroxytryptamine receptor 2A | |
| 54225 | Apob | apolipoprotein B | |
| 54315 | Ucp2 | uncoupling protein 2 | |
| 79114 | Fgfr1 | Fibroblast growth factor receptor 1 | |
| 83516 | Ppargc1a | PPARG coactivator 1 alpha | |
| 85431 | Nox4 | NADPH oxidase 4 |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 35362 | Mtp | Microsomal triacylglycerol transfer protein | |
| 37028 | ACOX1 | acyl-CoA oxidase 1 | |
| 39954 | Oatp74D | Organic anion transporting polypeptide 74D | |
| 41549 | Octbeta2R | Octopamine beta2 receptor | |
| 42160 | htl | heartless | |
| 42549 | InR | Insulin-like receptor | |
| 43191 | Hex-t2 | Hexokinase testis 2 | |
| 117364 | Hex-t1 | Hexokinase testis 1 |
| Gene ID | Gene Symbol | Description | Source | Organism |
|---|---|---|---|---|
| 378695 | ins.L | insulin L homeolog | Xenopus laevis (African clawed frog) | |
| 378696 | ins.S | insulin S homeolog | Xenopus laevis (African clawed frog) | |
| 395003 | dgat2 | diacylglycerol O-acyltransferase 2 | Xenopus tropicalis (tropical clawed frog) | |
| 397782 | fgfr1.S | fibroblast growth factor receptor 1 S homeolog | Xenopus laevis (African clawed frog) | |
| 399444 | fgfr1.L | fibroblast growth factor receptor 1 L homeolog | Xenopus laevis (African clawed frog) | |
| 548648 | fgfr1 | fibroblast growth factor receptor 1 | Xenopus tropicalis (tropical clawed frog) |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 171619 | C53D5.5 | Gamma-glutamyltranspeptidase 1 | |
| 171782 | abt-2 | ABC transporter domain-containing protein | |
| 174116 | gldi-2 | EGF-like domain-containing protein | |
| 175410 | daf-2 | Insulin-like receptor subunit beta;Protein kinase domain-containing protein;receptor protein-tyrosine kinase | |
| 176852 | dsc-4 | Microsomal triglyceride transfer protein homolog | |
| 177940 | egl-21 | Carboxypeptidase E | |
| 179053 | cpr-4 | Cathepsin B-like cysteine proteinase 4 | |
| 180033 | cpr-3 | Cathepsin B-like cysteine proteinase 3 | |
| 180289 | mrp-7 | Multidrug resistance protein mrp-7 | |
| 180364 | T03D8.6 | Gamma-glutamyltransferase;Gamma-glutamyltranspeptidase 1 |
