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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
steatotic liver disease
Summary
- Synonym
-
- Fatty change of liver
- SLD
- Steatosis of liver
- alcoholic fatty liver
- fatty liver disease
- hepatic lipidosis
- hepatic steatosis
- Definition
- A lipid storage disease characterized by the accumulation of large vacuoles of triglyceride fat in at least 5% of hepatocytes.
- Super Class
- lipid storage disease liver disease
External Links
- Disease Ontology
- DOID:9452
- Mondo Disease Ontology
- MeSH
- UMLS
- OMIM
- MGI genotype (from TogoID)
- WikiPathways (from TogoID)
Related Genes
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 19 | ABCA1 | ATP binding cassette subfamily A member 1 | |
| 31 | ACACA | acetyl-CoA carboxylase alpha | |
| 32 | ACACB | acetyl-CoA carboxylase beta | |
| 51 | ACOX1 | acyl-CoA oxidase 1 | |
| 154 | ADRB2 | adrenoceptor beta 2 | |
| 191 | AHCY | adenosylhomocysteinase | |
| 249 | ALPL | alkaline phosphatase, biomineralization associated | |
| 335 | APOA1 | apolipoprotein A1 | |
| 338 | APOB | apolipoprotein B | |
| 348 | APOE | apolipoprotein E |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 14598 | Ggt1 | gamma-glutamyltransferase 1 | |
| 14775 | Gpx1 | glutathione peroxidase 1 | |
| 14828 | Hspa5 | heat shock protein 5 | |
| 15558 | Htr2a | 5-hydroxytryptamine (serotonin) receptor 2A | |
| 15559 | Htr2b | 5-hydroxytryptamine (serotonin) receptor 2B | |
| 16153 | Il10 | interleukin 10 | |
| 16165 | Il13ra2 | interleukin 13 receptor, alpha 2 | |
| 16333 | Ins1 | insulin I | |
| 16334 | Ins2 | insulin II | |
| 16337 | Insr | insulin receptor |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 116568 | Ggt1 | gamma-glutamyltransferase 1 | |
| 140668 | Abcc3 | ATP binding cassette subfamily C member 3 | |
| 170538 | Prkcd | protein kinase C, delta | |
| 170670 | Hadha | hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha | |
| 170698 | Slco1a4 | solute carrier organic anion transporter family, member 1a4 | |
| 171155 | Hadhb | hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta | |
| 252900 | Dgat2 | diacylglycerol O-acyltransferase 2 | |
| 300438 | Ldlr | low density lipoprotein receptor | |
| 497840 | Cps1 | carbamoyl-phosphate synthase 1 |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 35362 | Mtp | Microsomal triacylglycerol transfer protein | |
| 37028 | ACOX1 | acyl-CoA oxidase 1 | |
| 39954 | Oatp74D | Organic anion transporting polypeptide 74D | |
| 41549 | Octbeta2R | Octopamine beta2 receptor | |
| 42160 | htl | heartless | |
| 42549 | InR | Insulin-like receptor | |
| 43191 | Hex-t2 | Hexokinase testis 2 | |
| 117364 | Hex-t1 | Hexokinase testis 1 |
| Gene ID | Gene Symbol | Description | Source | Organism |
|---|---|---|---|---|
| 378695 | ins.L | insulin L homeolog | Xenopus laevis (African clawed frog) | |
| 378696 | ins.S | insulin S homeolog | Xenopus laevis (African clawed frog) | |
| 395003 | dgat2 | diacylglycerol O-acyltransferase 2 | Xenopus tropicalis (tropical clawed frog) | |
| 397782 | fgfr1.S | fibroblast growth factor receptor 1 S homeolog | Xenopus laevis (African clawed frog) | |
| 399444 | fgfr1.L | fibroblast growth factor receptor 1 L homeolog | Xenopus laevis (African clawed frog) | |
| 548648 | fgfr1 | fibroblast growth factor receptor 1 | Xenopus tropicalis (tropical clawed frog) |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 171619 | C53D5.5 | Gamma-glutamyltranspeptidase 1 | |
| 171782 | abt-2 | ABC transporter domain-containing protein | |
| 174116 | gldi-2 | EGF-like domain-containing protein | |
| 175410 | daf-2 | Insulin-like receptor subunit beta;Protein kinase domain-containing protein;receptor protein-tyrosine kinase | |
| 176852 | dsc-4 | Microsomal triglyceride transfer protein homolog | |
| 177940 | egl-21 | Carboxypeptidase E | |
| 179053 | cpr-4 | Cathepsin B-like cysteine proteinase 4 | |
| 180033 | cpr-3 | Cathepsin B-like cysteine proteinase 3 | |
| 180289 | mrp-7 | Multidrug resistance protein mrp-7 | |
| 180364 | T03D8.6 | Gamma-glutamyltransferase;Gamma-glutamyltranspeptidase 1 |
