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Standards Ontologies Notations
type 1 diabetes mellitus

Summary
Synonym
  • IDDM
  • insulin-dependent diabetes mellitus
  • type I diabetes mellitus
Definition
A diabetes mellitus that is characterized by destruction of pancreatic beta cells resulting in absent or extremely low insulin production.
Super Class
autoimmune disease of endocrine system diabetes mellitus
External Links
Disease Ontology
DOID:9744
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
OMIM
GARD
MGI genotype (from TogoID)
Related Genes
Displaying entries 1 - 10 of 176 in total
Gene ID Gene Symbol Description Source
28 ABO ABO, alpha 1-3-N-acetylgalactosaminyltransferase and alpha 1-3-galactosyltransferase
43 ACHE acetylcholinesterase (Yt blood group)
128 ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide
142 PARP1 poly(ADP-ribose) polymerase 1
175 AGA aspartylglucosaminidase
176 ACAN aggrecan
217 ALDH2 aldehyde dehydrogenase 2 family member
224 ALDH3A2 aldehyde dehydrogenase 3 family member A2
231 AKR1B1 aldo-keto reductase family 1 member B
239 ALOX12 arachidonate 12-lipoxygenase, 12S type
Displaying entries 1 - 10 of 17 in total
Gene ID Gene Symbol Description Source
11450 Adipoq adiponectin, C1Q and collagen domain containing
11554 Adrb1 adrenergic receptor, beta 1
12494 Cd38 CD38 antigen
12654 Chi3l1 chitinase 3 like 1
14380 G6pd2 glucose-6-phosphate dehydrogenase 2
14381 G6pdx glucose-6-phosphate dehydrogenase X-linked
16002 Igf2 insulin-like growth factor 2
16177 Il1r1 interleukin 1 receptor, type I
16333 Ins1 insulin I
16334 Ins2 insulin II
Displaying entries 11 - 14 of 14 in total
Gene ID Gene Symbol Description Source
29260 Tlr4 toll-like receptor 4
29535 Pdx1 pancreatic and duodenal homeobox 1
64133 Xylt1 xylosyltransferase 1
89824 Chi3l1 chitinase 3 like 1
Displaying entries 11 - 20 of 31 in total
Gene ID Gene Symbol Description Source
37104 Idgf5 Imaginal disc growth factor 5
37420 Ugt49B1 UDP-glycosyltransferase family 49 member B1
38288 oxt peptide O-xylosyltransferase
40079 Ugt316A1 UDP-glycosyltransferase family 316 member A1
41334 Ugt35A1 UDP-glycosyltransferase family 35 member A1
41573 Ugt37A2 UDP-glycosyltransferase family 37 member A2
41574 Ugt37A3 UDP-glycosyltransferase family 37 member A3
42538 Ugt49B2 UDP-glycosyltransferase family 49 member B2
43222 Tl Toll
43223 Lerp lysosomal enzyme receptor protein
Displaying all 4 entries
Gene ID Gene Symbol Description Source
30262 ins preproinsulin
406731 ugt1ab UDP glucuronosyltransferase 1 family a, b
560951 xylt1 xylosyltransferase I
100384891 ugt1a7 UDP glucuronosyltransferase 1 family, polypeptide A7
Displaying all 7 entries
Gene ID Gene Symbol Description Source Organism
378695 ins.L insulin L homeolog Xenopus laevis (African clawed frog)
378696 ins.S insulin S homeolog Xenopus laevis (African clawed frog)
444363 xylt1.L xylosyltransferase I L homeolog Xenopus laevis (African clawed frog)
100135191 ugt1a6 UDP glucuronosyltransferase 1 family, polypeptide A6 Xenopus tropicalis (tropical clawed frog)
100145490 xylt1 xylosyltransferase I Xenopus tropicalis (tropical clawed frog)
100489505 ugt1a1 UDP glucuronosyltransferase 1 family, polypeptide A1 Xenopus tropicalis (tropical clawed frog)
108703114 xylt1.S xylosyltransferase I S homeolog Xenopus laevis (African clawed frog)
Displaying all 5 entries
Gene ID Gene Symbol Description Source
175591 ugt-62 UDP-glucuronosyltransferase
178046 gspd-1 Glucose-6-phosphate 1-dehydrogenase
180628 cht-1 putative endochitinase
189173 W03G11.3 Putative alpha-L-fucosidase
190099 sqv-6 Xylosyltransferase sqv-6;protein xylosyltransferase
Displaying all 3 entries
Gene ID Gene Symbol Description Source
850886 ATG26 sterol 3-beta-glucosyltransferase
851977 CTS2 putative chitinase
855480 ZWF1 glucose-6-phosphate dehydrogenase
Related Glycoprotein
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: August 19, 2024