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Goodpasture syndrome
Summary
- Synonym
-
- anti-GBM disease
- anti-glomerular basement membrane disease
- Definition
- An autoimmune disease that is characterized by antibody attack of the basement membrane in lungs and kidneys, leading to bleeding from the lungs and kidney failure.
- Super Class
- autoimmune disease of urogenital tract kidney disease lung disease
Related Genes
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 28 | ABO | ABO, alpha 1-3-N-acetylgalactosaminyltransferase and alpha 1-3-galactosyltransferase | |
| 1056 | CEL | carboxyl ester lipase | |
| 1116 | CHI3L1 | chitinase 3 like 1 | |
| 1588 | CYP19A1 | cytochrome P450 family 19 subfamily A member 1 | |
| 1589 | CYP21A2 | cytochrome P450 family 21 subfamily A member 2 | |
| 1636 | ACE | angiotensin I converting enzyme | |
| 2215 | FCGR3B | Fc gamma receptor IIIb | |
| 2717 | GLA | galactosidase alpha | |
| 3820 | KLRB1 | killer cell lectin like receptor B1 | |
| 4907 | NT5E | 5'-nucleotidase ecto |
Related Glycoprotein
| UniProt ID | Protein Name | Source |
|---|---|---|
| O15327 | Inositol polyphosphate 4-phosphatase type II | |
| O75015 | Low affinity immunoglobulin gamma Fc region receptor III-B | |
| P06280 | Alpha-galactosidase A | |
| P12821 | Angiotensin-converting enzyme | |
| P16109 | P-selectin | |
| P16442 | Histo-blood group ABO system transferase | |
| P19320 | Vascular cell adhesion protein 1 | |
| P19835 | Bile salt-activated lipase | |
| P21589 | 5'-nucleotidase | |
| P36222 | Chitinase-3-like protein 1 |
