GlyCosmos Portal

GlyCosmos Diseases

List of diseases involving glycan related genes. The information of each database of Glyco-Disease Genes Database (GDGDB), DisGeNET, and Alliance of Genome Resources is integrated into one list.

Database	Last Updated
Alliance of Genome Resources	February 28, 2024
DisGeNET	February 14, 2024
Glyco-Disease Genes Database (GDGDB)	January 25, 2017

Disease ID	Disease Name	Gene Symbol ▲	Gene ID
DOID:0080181	PHARC syndrome	ABHD12 Abhd12 Abhd12 abhd12 abhd12	100216158 26090 499913 76192 767657
DOID:0112342	hereditary spastic paraplegia 86	ABHD16A Abhd16a Abhd16a	193742 361796 7920
DOID:0050729	Chanarin-Dorfman syndrome	ABHD4 Abhd4 CLD1 PNPLA2 PNPLA3 PNPLA5 Pnpla2 Pnpla2 Pnpla3 Pnpla5 abhd-5.2 atgl-1	105501 116939 150379 175910 178877 361676 57104 63874 66853 75772 80339 853007
DOID:2394	ovarian cancer	ABHD8 ANXA7 ATG26 C25G4.2 CALR CDH13 CG5412 CHI3L1 COMT CTS2 CYP19A1 Calr GBGT1 HDAC3 HOS2 HPRT1 HRAS HS3ST2 Hdac3 Hdac3 ICAM1 IGF2R Idgf1 Idgf2 Idgf3 Idgf4 MBL2 MRC1 MSLN OGG1 OGG1 OPCML OVCA2 Ogg1 Ogg1 Ogg1 Ovca2 PIK3CA POL2 POLE PRSS8 PTEN PTGS1 PolE1 Pole Rrp1 SHMT1 STS TEP1 TNFRSF10C TUSC3 TYMP Tymp Tymp UGT1A1 Ugt1a1 Ugt1a1 Ugt301D1 Ugt302K1 Ugt303A1 Ugt304A1 Ugt316A1 Ugt35A1 Ugt35C1 Ugt35E2 Ugt36D1 Ugt36E1 Ugt36F1 Ugt37A3 Ugt37C1 Ugt37D1 Ugt37E1 Ugt49B2 cht-1 hda-2 hdac3.S hdac3 hdac3 ovca2 ugt-61 ugt1a1 ugt1a6 ugt1a7 ugt1ab	100135191 100384891 100489505 1012 10232 1116 124641 1312 15183 1588 174285 178194 180628 18294 185500 1890 18973 246257 24861 26301 310 315219 31806 31926 3251 3265 33500 3383 3482 34978 34979 34981 35105 35137 35138 35139 393965 394436 40079 406731 41166 412 41334 4153 41574 42434 42538 42758 432017 4360 4968 4978 5290 53501 53502 53503 53506 53507 53511 53512 53583 5426 54658 549637 553576 5652 5728 5742 6470 72962 79575 7991 811 81528 84578 850886 851977 852681 854942 855459 855595 8794 8841 9956
DOID:4001	ovarian carcinoma	ABHD8 BI4 CDH13 GBGT1 HDAC3 HOS2 HRAS HS3ST2 Hdac3 Hdac3 IGF2R L1CAM MRC1 OPCML PTEN RHO1 RHO2 RHOA Rhoa Rhoa STS TNFRSF10C TUSC3 hda-2 hdac3.S hdac3 hdac3	1012 117273 11848 15183 174285 26301 3265 3482 387 3897 393965 412 432017 4360 4978 549637 5728 79575 7991 84578 852681 854582 855634 856294 8794 8841 9956
DOID:1240	leukemia	ABO ACE ACSL6 AKR1C3 Abo2 Abo3 Abo Abo EXT1 FHIT GPX1 GPX3 HDAC1 HRAS Hras Hras KRAS Kras Kras MRC1 NRAS Nras PIK3CA PIK3CB PIK3CD PIK3CG PLA2R1 RAS1 RAS2 Ras85D TNFRSF10C TUB3 abo.1 abo.2.L abo.2 abo.3.L abo.3 abo.4.L abo.4 gbgt1l2 gbgt1l3 gbgt1l4 gbgt1l5 gbgt1l8	100005565 100301568 100497509 108698211 108698863 15461 1636 16653 2131 2272 22925 23305 24525 24605 28 2876 2878 293621 296504 3065 3265 3845 387303 41140 4360 447881 4893 495825 5290 5291 5293 5294 549437 549858 550054 563897 566487 65270 80908 854268 854915 855625 8644 8794
DOID:0080600	COVID-19	ABO ACE Abo2 Abo3 Abo Abo BDH1 IL1R1 Il1r1 LGALS3 SELE abo.1 abo.2.L abo.2 abo.3.L abo.3 abo.4.L abo.4 fw gbgt1l2 gbgt1l3 gbgt1l4 gbgt1l5 gbgt1l8	100005565 100301568 100497509 108698211 108698863 16177 1636 28 296504 32162 3554 387303 3958 447881 495825 549437 549858 550054 563897 566487 622 6401 65270 80908
DOID:552	pneumonia	ABO ACE Abo2 Abo3 Abo Abo CD14 CYP1A1 CYP2E1 ICAM1 MBL2 REG3G SFTPA1 SFTPD abo.1 abo.2.L abo.2 abo.3.L abo.3 abo.4.L abo.4 gbgt1l2 gbgt1l3 gbgt1l4 gbgt1l5 gbgt1l8	100005565 100301568 100497509 108698211 108698863 130120 1543 1571 1636 28 296504 3383 387303 4153 447881 495825 549437 549858 550054 563897 566487 6441 65270 653509 80908 929
DOID:9952	acute lymphoblastic leukemia	ABO AICDA ATIC Abo2 Abo3 Abo Abo Aicda CG8891 CSPG4 CYP1A1 CYP1B1 CYP3A5 Dntt EPHX1 Ephx1 Ephx1 FHIT GPI GPX1 HAM1 HDAC1 HDAC1 HDAC2 HDAC4 HK1 Hdac1 Hdac1 Hdac2 Hdac4 Hdac4 ITPA Itpa Itpa KRAS Kras Kras NRAS Nras PON1 PTEN Pon1 Pon1 RPD3 Ras85D TEP1 abo.1 abo.2.L abo.2 abo.3.L abo.3 abo.4.L abo.4 gbgt1l2 gbgt1l3 gbgt1l4 gbgt1l5 gbgt1l8 hap-1 hda-1 hda-4 hdac1.L itpa.S itpa nras.L	100005565 100301568 100497509 108698211 108698863 11628 13849 1464 15182 1543 1545 1577 16434 16653 175724 179959 181723 18979 2052 208727 21673 2272 24525 24605 25315 28 2821 2876 296504 297893 3065 3066 3098 311422 33718 363287 3704 3845 38565 387303 397868 399446 41140 433759 447881 471 4893 495825 5444 549437 549858 550054 557834 563897 566487 5728 57379 65270 735008 80908 84024 853532 855386 855595 9759
DOID:11054	urinary bladder cancer	ABO ALOX12 AMACR Alox12 BI4 BST2 CD44 CDH13 COMT CYP1A1 CYP1B1 CYP2C9 ENO1 ENO2 ENO2 EPHX1 Ephx1 Ephx1 FHIT Fhit Fhit HDAC2 HK1 HNT2 HPSE HRAS HSP90AA1 Hras Hras ICAM1 KRAS Kras Kras MRC1 Mras PTEN PTGS2 RAS1 RHO1 RHO2 RHOA RRAS2 RRAS Ras64B Ras85D Rhoa Rhoa Rras2 Rras Rras Rrp1 TEP1 TNFRSF10C TYMP Tymp Tymp	1012 10855 11684 117273 11848 1312 13849 14198 1543 1545 15461 1559 16653 17532 1890 20130 2026 2052 2272 22800 23600 239 24525 25315 28 293621 3066 3098 315219 3265 3320 33500 3383 361568 3845 38494 387 41140 4360 5728 5743 60398 6237 66922 684 72962 851899 853169 854268 854582 855595 855634 856294 856579 8794 960