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Glycan Structure Repository
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Glycoconjugate Repository
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Glycomics MS raw data Repository
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Glycomics MS Repository for glycan annotations from GlycoWorkbench
LM-GlycoRepo
Repository for lectin-assisted multimodality data
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MIRAGE
Lymphotoxin-alpha
Summary
- UniProt ID
- P01374
- Gene Symbol
-
- LTA
- TNFB
- TNFSF1
- Gene ID
- 4049
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Cytokine
- Direct protein sequencing
- Glycoprotein
- Membrane
- Reference proteome
- Secreted
- Signal
- Gene Ontology (GO)
| GO Term |
|---|
| extracellular space |
| plasma membrane |
| GO Term |
|---|
| signaling receptor binding |
| cytokine activity |
| tumor necrosis factor receptor binding |
Sequence
MTPPERLFLPRVCGTTLHLLLLGLLLVLLPGAQGLPGVGLTPSAAQTARQHPKMHLAHSTLKPAAHLIGDPSKQNSLLWRANTDRAFLQDGFSLSNNSLLVPTSGIYFVYSQVVFSGKAYSPKATSSPLYLAHEVQLFSSQYPFHVPLLSSQKMVYPGLQEPWLHSMYHGAAFQLTQGDQLSTHTDGIPHLVLSPSTVFFGAFAL
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 41 | O-linked (GalNAc...) threonine; partial |
|
||
| 96 | N-linked (GlcNAc...) asparagine |
G63889NK
G90093AU
G45359RY
G72797UR
G86357DX
G29228MX
G52038JM
G91636VS
G23863VK
G78059CC
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway | Homo sapiens |
| TNFR2 non-canonical NF-kB pathway | Homo sapiens |
| TNFs bind their physiological receptors | Homo sapiens |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:418 | systemic scleroderma | |
| DOID:4398 | pustulosis of palm and sole | |
| DOID:5844 | myocardial infarction | |
| DOID:8505 | dermatitis herpetiformis | |
| DOID:8893 | psoriasis | |
| DOID:8947 | diabetic retinopathy | |
| DOID:9008 | psoriatic arthritis | |
| DOID:9146 | visceral leishmaniasis | |
| DOID:9155 | mucocutaneous leishmaniasis | |
| DOID:9352 | type 2 diabetes mellitus |
