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Erythropoietin

Summary

UniProt ID

P01588

Gene Symbol

Organism

Homo sapiens (human)

External Links

GlyConnect

GlyGen

P01588

PubChem

P01588

Annotation

Keyword

3D-structure
Congenital erythrocytosis
Direct protein sequencing
Disease variant
Disulfide bond
Erythrocyte maturation
Glycoprotein
Hormone
Pharmaceutical
Reference proteome
Secreted
Signal

Gene Ontology (GO)

Displaying entries **31 - 34** of 34 in total

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GO Term
response to interleukin-1
cellular hyperosmotic response
negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress
negative regulation of erythrocyte apoptotic process

Displaying **all 4** entries
GO Term
cell surface
extracellular region
extracellular space
cell body

Displaying **all 4** entries
GO Term
protein kinase activator activity
hormone activity
cytokine activity
erythropoietin receptor binding

Annotation information from UniProt.

Sequence

MGVHECPAWLWLLLSLLSLPLGLPVLGAPPRLICDSRVLERYLLEAKEAENITTGCAEHCSLNENITVPDTKVNFYAWKRMEVGQQAVEVWQGLALLSEAVLRGQALLVNSSQPWEPLQLHVDKAVSGLRSLTTLLRALGAQKEAISPPDAASAAPLRTITADTFRKLFRVYSNFLRGKLKLYTGEACRTGDR

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 5** entries
Position	Description	PubMed ID	GlyTouCan ID	Source
51	N-linked (GlcNAc...) asparagine	3949763	G25392ZR G48109OV G91152KU G16208YZ G49446SO G62619LG G82410AF G84390MS G27844UM G28103WK G57581QG G74859XI G22721QX G13282WA G40027VO G47279LF G48488CO G90784AP G96719MC G98259QP G13165FV G69834CE G94531EZ G18639PA G83108TD G16873YG G72886NH G39643OJ G39952PY G39595FH G50489VC G56516KW G68892PJ G86696LV G86753CK G90789YQ G92574YO G67506FN G60984DZ G94309NZ G10148VG G14199EY G62461SM G58598BO G02311IE G17155VX G40194MN G64394MX G83295QG G19603RR G56811US G94974XB G15169WU G91413ZX G57888GL G12436UO G45116BB G88976TU G34617SM G68209WQ G01450UB G10228OD G11629QQ G16529MG G62765SF G80537QW G91905FJ G96503EZ G45883VE G75520NV G68796US G25379SA G27290LL G14796IU G63889NK G67610NV G90093AU G29501UT G54639VI G81263BG G97428EW G06330RB G52122ZD G18938DW G08146BT G17689DH G22310AV G33284WZ G70375MX G61962FK G48414YA G83676GD G81107PN G89098OM G00551JZ G45359RY G72797UR G86357DX G31838XA G70822IO G30460NZ G45495MK G53752TA G84452RH G10773YW G29857RC G79809MM G20218ZS G91636VS G00249IY G44215PV G14994KB G43761WH G79568CQ G03382KH G50888WV G23863VK G78059CC G88696CU G23869AA G36191CD G46687AB G51057KO G92709EO G02561FC G81295CK G93180LE G49874UX G53492UE G09176OA G29880MM G50707YR G90448RI G35364KM G94854LT	UniProt GlyGen GlyConnect
65	N-linked (GlcNAc...) asparagine	3949763	G25392ZR G48109OV G91152KU G16208YZ G49446SO G62619LG G82410AF G84390MS G27844UM G28103WK G57581QG G74859XI G22721QX G13282WA G40027VO G47279LF G48488CO G90784AP G96719MC G98259QP G05813WO G13165FV G69834CE G94531EZ G18639PA G83108TD G42459UQ G16873YG G72886NH G39643OJ G39952PY G39595FH G50489VC G56516KW G68892PJ G86696LV G86753CK G90789YQ G92574YO G67506FN G31665QC G78166NF G12793SR G83213GG G10148VG G14199EY G62461SM G58598BO G02311IE G17155VX G40194MN G64394MX G83295QG G19603RR G56811US G94974XB G15169WU G91413ZX G31153XO G93656SY G57888GL G12436UO G34617SM G68209WQ G01450UB G10228OD G11629QQ G16529MG G62765SF G80537QW G91905FJ G96503EZ G45883VE G75520NV G52527GH G63889NK G67610NV G81263BG G18938DW G17689DH G22310AV G33284WZ G52782YT G66163OV G83676GD G81107PN G00551JZ G45359RY G86357DX G72667IM G30460NZ G45495MK G53752TA G84452RH G10773YW G29857RC G79809MM G20218ZS G60723SV G00249IY G44215PV G43761WH G50888WV G78059CC G88696CU G36191CD G51057KO G55383ZG G92709EO G02561FC G93180LE G09176OA G29880MM G90448RI	UniProt GlyGen GlyConnect
110	N-linked (GlcNAc...) asparagine	3949763	G25392ZR G48109OV G71549MK G91152KU G11528MV G26777RD G16208YZ G49446SO G62619LG G82410AF G84390MS G27844UM G28103WK G57581QG G74859XI G04959WS G22721QX G13282WA G40027VO G47279LF G48488CO G90784AP G96719MC G98259QP G13165FV G69834CE G94531EZ G18639PA G83108TD G23165GD G16873YG G72886NH G39643OJ G39952PY G39595FH G50489VC G56516KW G68892PJ G86696LV G86753CK G90789YQ G92574YO G67506FN G31665QC G78166NF G10148VG G14199EY G58598BO G02311IE G17155VX G40194MN G64394MX G83295QG G19603RR G56811US G94974XB G15169WU G84331QL G91413ZX G57888GL G12436UO G47518TP G45116BB G88976TU G34617SM G68209WQ G00553AN G01450UB G10228OD G11629QQ G16529MG G62765SF G80537QW G91905FJ G96503EZ G45883VE G75520NV G31596VW G63889NK G67610NV G90093AU G57248BB G81263BG G18938DW G17689DH G22310AV G33284WZ G81107PN G00551JZ G45359RY G72797UR G86357DX G30460NZ G45495MK G53752TA G84452RH G29857RC G79809MM G20218ZS G43761WH G50888WV G78059CC G88696CU G36191CD G51057KO G92709EO G02561FC G09176OA	UniProt GlyGen GlyConnect
153	O-linked (GalNAc...) serine	3949763	G27945LI G01614ZM G81006GJ G49644CL G48809BS G60554YG G47967RK G47190LU G56682BC G74722FL G46831QF G19399OS G47318KU G71838YU G00031MO G29931IJ G57321FI	UniProt GlyGen GlyConnect
			G25392ZR G48109OV G71549MK G59742GY G91152KU G11528MV G26777RD G16208YZ G49446SO G62619LG G82410AF G84390MS G31380TD G58039UH G75154UG G27844UM G57581QG G74859XI G04959WS G22721QX G13282WA G26775OX G29097SS G40027VO G47279LF G48488CO G90784AP G96719MC G98259QP G05813WO G88027AL G69834CE G94531EZ G09576QH G16873YG G72886NH G14389GM G39595FH G50489VC G56516KW G68892PJ G86696LV G86753CK G92574YO G23305TF G51562OR G70894RY G19972YZ G84756CG G02311IE G17155VX G40194MN G57789QC G64394MX G98568VG G94974XB G15169WU G45209NR G91413ZX G12436UO G31544HA G31991IV G40428GO G77149EE G14950CY G77582RK G10228OD G11629QQ G16529MG G62765SF G80537QW G91905FJ G96503EZ G07410AW G16679DU G63889NK G90093AU G18938DW G47012YE G17689DH G22310AV G28948UC G45359RY G72797UR G86357DX G30460NZ G53752TA G84452RH G20425TQ G29857RC G79809MM G13441ZL G53322JT G23863VK G78059CC G36191CD G50045TK G50707YR G01614ZM G81006GJ G56682BC G65562ZE G74722FL G19399OS G36123IU G00031MO G29931IJ G57321FI	GlyGen GlyConnect

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 6** entries
Pathway Name	Organism
Erythropoietin activates Phosphoinositide-3-kinase (PI3K)	Homo sapiens
Erythropoietin activates Phospholipase C gamma (PLCG)	Homo sapiens
Erythropoietin activates RAS	Homo sapiens
Erythropoietin activates STAT5	Homo sapiens
Regulation of gene expression by Hypoxia-inducible Factor	Homo sapiens
Signaling by Erythropoietin	Homo sapiens

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

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External Links

Annotation

International Collaboration

Acknowledgements