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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Hepatocyte growth factor
Summary
- UniProt ID
- P14210
- Gene Symbol
-
- HGF
- HPTA
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Direct protein sequencing
- Disulfide bond
- Glycoprotein
- Growth factor
- Kringle
- Non-syndromic deafness
- Pyrrolidone carboxylic acid
- Reference proteome
- Repeat
- Serine protease homolog
- Signal
- Gene Ontology (GO)
| GO Term |
|---|
| extracellular region |
| extracellular space |
| membrane |
| platelet alpha granule lumen |
| GO Term |
|---|
| growth factor activity |
| identical protein binding |
| chemoattractant activity |
| signaling receptor binding |
Sequence
MWVTKLLPALLLQHVLLHLLLLPIAIPYAEGQRKRRNTIHEFKKSAKTTLIKIDPALKIKTKKVNTADQCANRCTRNKGLPFTCKAFVFDKARKQCLWFPFNSMSSGVKKEFGHEFDLYENKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQENYCRNPRGEEGGPWCFTSNPEVRYEVCDIPQCSEVECMTCNGESYRGLMDHTESGKICQRWDHQTPHRHKFLPERYPDKGFDDNYCRNPDGQPRPWCYTLDPHTRWEYCAIKTCADNTMNDTDVPLETTECIQGQGEGYRGTVNTIWNGIPCQRWDSQYPHEHDMTPENFKCKDLRENYCRNPDGSESPWCFTTDPNIRVGYCSQIPNCDMSHGQDCYRGNGKNYMGNLSQTRSGLTCSMWDKNMEDLHRHIFWEPDASKLNENYCRNPDDDAHGPWCYTGNPLIPWDYCPISRCEGDTTPTIVNLDHPVISCAKTKQLRVVNGIPTRTNIGWMVSLRYRNKHICGGSLIKESWVLTARQCFPSRDLKDYEAWLGIHDVHGRGDEKCKQVLNVSQLVYGPEGSDLVLMKLARPAVLDDFVSTIDLPNYGCTIPEKTSCSVYGWGYTGLINYDGLLRVAHLYIMGNEKCSQHHRGKVTLNESEICAGAEKIGSGPCEGDYGGPLVCEQHKMRMVLGVIVPGRGCAIPNRPGIFVRVAYYAKWIHKIILTYKVPQS
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 294 |
|
|||
| 402 |
|
|||
| 476 | O-linked (GalNAc...) threonine | |||
| 566 |
|
|||
| 653 |
|
G57789QC
G64394MX
G60542VK
G93656SY
G01543ZX
G11629QQ
G74239ZQ
G52126RR
G52527GH
G89664KV
G17689DH
G22310AV
G48414YA
G77252PU
G45637XA
G81006GJ
G86880BF
G40834TG
G45395BF
G08918WF
G27126ED
G04657PL
G27058EU
G41071NU
G42124LM
G90659AW
G46691LC
G83460ZZ
G80920RR
G62765YT
G41247ZX
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Constitutive Signaling by Aberrant PI3K in Cancer | Homo sapiens |
| Drug-mediated inhibition of MET activation | Homo sapiens |
| Interleukin-4 and Interleukin-13 signaling | Homo sapiens |
| Interleukin-7 signaling | Homo sapiens |
| MET Receptor Activation | Homo sapiens |
| MET activates PI3K/AKT signaling | Homo sapiens |
| MET activates PTK2 signaling | Homo sapiens |
| MET activates PTPN11 | Homo sapiens |
| MET activates RAP1 and RAC1 | Homo sapiens |
| MET activates RAS signaling | Homo sapiens |
