Submissions
GlyTouCan
Glycan Structure Repository
GlyComb
Glycoconjugate Repository
GlycoPOST
Glycomics MS raw data Repository
UniCarb-DR
Glycomics MS Repository for glycan annotations from GlycoWorkbench
LM-GlycoRepo
Repository for lectin-assisted multimodality data
Resources Genes Glycoproteins Lectins Glycolipids Glycans Pathways Diseases Organisms
All Resources
Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Other Information
Release Statistics Download
Tools
SugarDrawer GlycanBuilder Glycan Converters GlycoMaple GlycomeAtlas LM-GlycomeAtlas GALAXY MCAW GlycoSim GRable
Search Tools
Cross Search Glycan Search Publication Search Programmatic Access
Standards Ontologies Notations
Guidelines
MIRAGE
Tyrosine-protein kinase JAK1

Summary
UniProt ID
P23458
Gene Symbol
  • JAK1
  • JAK1A
  • JAK1B
Gene ID
3716
Organism
Homo sapiens (human)
GlyConnect
GlyGen
P23458
PubChem
P23458
The Human Metabolome Database
HMDBP01309
RaftProt
P23458
Re-Glyco
P23458
Annotation
Keyword
  • 3D-structure
  • ATP-binding
  • Acetylation
  • Disease variant
  • Magnesium
  • Membrane
  • Metal-binding
  • Phosphoprotein
  • Reference proteome
  • Repeat
  • SH2 domain
  • Tyrosine-protein kinase
  • Ubl conjugation
Gene Ontology (GO)
Displaying all 9 entries
GO Term
nucleus
cytoplasm
cytoskeleton
plasma membrane
endosome
cytosol
focal adhesion
cytoplasmic side of plasma membrane
extrinsic component of cytoplasmic side of plasma membrane
Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Annotation information from UniProt.
Sequence
MQYLNIKEDCNAMAFCAKMRSSKKTEVNLEAPEPGVEVIFYLSDREPLRLGSGEYTAEELCIRAAQACRISPLCHNLFALYDENTKLWYAPNRTITVDDKMSLRLHYRMRFYFTNWHGTNDNEQSVWRHSPKKQKNGYEKKKIPDATPLLDASSLEYLFAQGQYDLVKCLAPIRDPKTEQDGHDIENECLGMAVLAISHYAMMKKMQLPELPKDISYKRYIPETLNKSIRQRNLLTRMRINNVFKDFLKEFNNKTICDSSVSTHDLKVKYLATLETLTKHYGAEIFETSMLLISSENEMNWFHSNDGGNVLYYEVMVTGNLGIQWRHKPNVVSVEKEKNKLKRKKLENKHKKDEEKNKIREEWNNFSYFPEITHIVIKESVVSINKQDNKKMELKLSSHEEALSFVSLVDGYFRLTADAHHYLCTDVAPPLIVHNIQNGCHGPICTEYAINKLRQEGSEEGMYVLRWSCTDFDNILMTVTCFEKSEQVQGAQKQFKNFQIEVQKGRYSLHGSDRSFPSLGDLMSHLKKQILRTDNISFMLKRCCQPKPREISNLLVATKKAQEWQPVYPMSQLSFDRILKKDLVQGEHLGRGTRTHIYSGTLMDYKDDEGTSEEKKIKVILKVLDPSHRDISLAFFEAASMMRQVSHKHIVYLYGVCVRDVENIMVEEFVEGGPLDLFMHRKSDVLTTPWKFKVAKQLASALSYLEDKDLVHGNVCTKNLLLAREGIDSECGPFIKLSDPGIPITVLSRQECIERIPWIAPECVEDSKNLSVAADKWSFGTTLWEICYNGEIPLKDKTLIEKERFYESRCRPVTPSCKELADLMTRCMNYDPNQRPFFRAIMRDINKLEEQNPDIVSEKKPATEVDPTHFEKRFLKRIRDLGEGHFGKVELCRYDPEGDNTGEQVAVKSLKPESGGNHIADLKKEIEILRNLYHENIVKYKGICTEDGGNGIKLIMEFLPSGSLKEYLPKNKNKINLKQQLKYAVQICKGMDYLGSRQYVHRDLAARNVLVESEHQVKIGDFGLTKAIETDKEYYTVKDDRDSPVFWYAPECLMQSKFYIASDVWSFGVTLHELLTYCDSDSSPMALFLKMIGPTHGQMTVTRLVNTLKEGKRLPCPPNCPDEVYQLMRKCWEFQPSNRTSFQNLIEGFEALLK
  • N : N-glycosylation Site
  • ___ : Potential Sequon
Glycosylation Sites
Displaying all 3 entries
Position Description PubMed ID GlyTouCan ID Source
769
814
1095
Feature
  • ProtVista GlyGen : Glycosylation Site from GlyGen
  • ProtVista UniProt : Glycosylation Site from UniProt
Pathway
Displaying entries 11 - 20 of 29 in total
Pathway Name Organism
Interleukin-15 signaling Homo sapiens
Interleukin-2 signaling Homo sapiens
Interleukin-20 family signaling Homo sapiens
Interleukin-21 signaling Homo sapiens
Interleukin-27 signaling Homo sapiens
Interleukin-35 Signalling Homo sapiens
Interleukin-4 and Interleukin-13 signaling Homo sapiens
Interleukin-6 signaling Homo sapiens
Interleukin-7 signaling Homo sapiens
Interleukin-9 signaling Homo sapiens
Disease
Displaying all 9 entries
DO ID Disease Name Source
DOID:10283 prostate cancer
DOID:10534 stomach cancer
DOID:1380 endometrial cancer
DOID:2394 ovarian cancer
DOID:3908 lung non-small cell carcinoma
DOID:4074 pancreatic adenocarcinoma
DOID:5603 T-cell acute lymphoblastic leukemia
DOID:684 hepatocellular carcinoma
DOID:9256 colorectal cancer
About Release Notes Help Feedback

Click here to visit the beta site.

International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

Logo License Policies Site Map

Contact: support@glycosmos.org

This work is licensed under Creative Commons Attribution 4.0 International

GlyCosmos Portal v4.2.1

Last updated: April 7, 2025