MAP3K8 (TPL2)-dependent MAPK1/3 activation
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- Abin2
- Btrcp2
- Chuk
- Cot
- Cul1
- Fbw1b
- Fbxw11
- Fbxw1b
- Ikbkb
- Ikbkg
- Ikka
- Ikkb
- Map3k8
- Nemo
- Nfkb1
- Rps27a
- Skp1
- Skp1a
- Tnip2
- Tpl2
- Uba52
- Uba80
- Ubb
- Ubc
- Ubcep1
- Ubcep2
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Recognition of DNA damage by PCNA-containing replication complex
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- Cdt2
- Cul4a
- Cul4b
- Ddb1
- Dtl
- Ibf-1
- Kiaa0695
- Kiaa1449
- L2dtl
- Pcna
- Pold1
- Pold2
- Pold3
- Pold4
- Pole
- Pole1
- Pole2
- Pole3
- Pole4
- Rad18
- Rad18sc
- Rad6b
- Ramp
- Rbx1
- Recc1
- Rfc1
- Rfc2
- Rfc3
- Rfc4
- Rfc5
- Rpa1
- Rpa2
- Rpa3
- Rpa34
- Rps27a
- Uaf1
- Uba52
- Uba80
- Ubb
- Ubc
- Ubcep1
- Ubcep2
- Ube2b
- Usp1
- Wdr48
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Downregulation of ERBB2 signaling
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- Bcn
- Btc
- Cdc37
- Chip
- Ctk
- Cul5
- Dtr
- Egf
- Egfr
- Erbb2
- Erbb2ip
- Erbb3
- Erbb4
- Erbin
- Ereg
- Flp1
- Hbegf
- Hegfl
- Hsp86
- Hsp86-1
- Hsp90aa1
- Hspca
- Kiaa1225
- Kiaa3023
- Lap2
- Matk
- Mer4
- Neu
- Nrg1
- Nrg2
- Nrg3
- Ntk
- Ptpk1
- Ptpn12
- Ptpn18
- Rps27a
- Stub1
- Uba52
- Uba80
- Ubb
- Ubc
- Ubcep1
- Ubcep2
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Inactivation of CSF3 (G-CSF) signaling
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- Cis3
- Cish1
- Cish3
- Csf3
- Csfg
- Cul5
- Elob
- Eloc
- Hck
- Jak1
- Jak2
- Lyn
- Rbx2
- Rnf7
- Rps27a
- Sag
- Socs1
- Socs3
- Ssi1
- Syk
- Sykb
- Tceb1
- Tceb2
- Tyk2
- Uba52
- Uba80
- Ubb
- Ubc
- Ubc4
- Ubcep1
- Ubcep2
- Ubch4
- Ubch5b
- Ube2d1
- Ube2d2
- Ube2d2a
- Ube2d3
- ptk72
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CREB phosphorylation
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- Atf1
- Creb-1
- Creb1
- Mapkapk1a
- Mapkapk1b
- Mapkapk1c
- Mapkapk2
- Msk1
- Rps6ka-rs1
- Rps6ka1
- Rps6ka2
- Rps6ka3
- Rps6ka5
- Rps6kc1
- Rsk1
- Rsk2
- Rsk3
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Activation of the AP-1 family of transcription factors
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- Atf2
- Crk1
- Csbp1
- Csbp2
- Erk1
- Erk2
- Fos
- Jnk1
- Jnk2
- Jnk3
- Jun
- Mapk
- Mapk1
- Mapk10
- Mapk11
- Mapk14
- Mapk3
- Mapk8
- Mapk9
- Prkm1
- Prkm10
- Prkm11
- Prkm3
- Prkm8
- Prkm9
- Serk2
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ATF6 (ATF6-alpha) activates chaperones
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- Atf6
- Mbtps1
- Mbtps2
- S1p
- Ski1
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ATF6B (ATF6-beta) activates chaperones
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- Atf6b
- Crebl1
- Mbtps1
- Mbtps2
- S1p
- Ski1
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Estrogen-dependent nuclear events downstream of ESR-membrane signaling
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- Akt
- Akt1
- Akt2
- Akt3
- Cdkn1b
- Creb-1
- Creb1
- Crm1
- Erk2
- Fkhr2
- Foxo3
- Foxo3a
- Kis
- Kist
- Mapk
- Mapk1
- Prkm1
- Rac
- Uhmk1
- Xpo1
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AKT phosphorylates targets in the nucleus
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- Afx
- Afx1
- Akt
- Akt1
- Akt2
- Akt3
- Creb-1
- Creb1
- Fkhr
- Fkhr2
- Fkhr3
- Foxo1
- Foxo1a
- Foxo3
- Foxo3a
- Foxo4
- Foxo6
- Gfrp
- Hmr
- Mllt7
- N10
- Nr4a1
- Nur77
- Rac
- Rps6kb2
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NCAM signaling for neurite out-growth
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- Creb-1
- Creb1
- Elf
- Erk1
- Erk2
- Fyn
- Hras
- Hras1
- Kras
- Kras2
- Lrp
- Mapk
- Mapk1
- Mapk3
- Msk1
- Ncam
- Ncam1
- Nras
- Prkm1
- Prkm3
- Ptpa
- Ptpra
- Rps6ka5
- Sos1
- Spna1
- Spna2
- Spnb-1
- Spnb-2
- Spnb1
- Spnb2
- Spnb3
- Spnb4
- Spta
- Spta1
- Spta2
- Sptan1
- Sptb
- Sptb1
- Sptb2
- Sptbn1
- Sptbn2
- Sptbn4
- Sptbn5
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Gastrin-CREB signalling pathway via PKC and MAPK
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- Bmk1
- Cckbr
- Creb-1
- Creb1
- Erk1
- Erk2
- Erk5
- Gas
- Gast
- Mapk
- Mapk1
- Mapk3
- Mapk7
- Mapkapk1a
- Mapkapk1b
- Mapkapk1c
- Prkm1
- Prkm3
- Rps6ka-rs1
- Rps6ka1
- Rps6ka2
- Rps6ka3
- Rsk1
- Rsk2
- Rsk3
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CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling
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- Creb-1
- Creb1
- Mapkapk1a
- Mapkapk1b
- Mapkapk1c
- Rps6ka-rs1
- Rps6ka1
- Rps6ka2
- Rps6ka3
- Rps6ka6
- Rsk1
- Rsk2
- Rsk3
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Activation of the phototransduction cascade
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- Cncg
- Cncg1
- Cnga1
- Cngb1
- Gnat-1
- Gnat1
- Gnb1
- Gng1
- Gngt1
- Mpa
- Mpb
- Pde6a
- Pde6b
- Pde6g
- Pdea
- Pdeb
- Pdeg
- Rho
- rd
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p53-Dependent G1 DNA Damage Response
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- Ccna
- Ccna1
- Ccna2
- Ccne
- Ccne1
- Ccne2
- Cdk2
- Cdkn1a
- Cdkn1b
- Cdkn2
- Cip1
- Cyca
- Cyca2
- Waf1
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G0 and Early G1
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- Bara
- Ccna
- Ccna1
- Ccna2
- Ccne
- Ccne1
- Ccne2
- Cdk2
- Cdkn2
- Cyca
- Cyca2
- Dp2
- Dyrk
- Dyrk1a
- E2f4
- E2f5
- Hdac1
- Kiaa2037
- Lin37
- Lin52
- Lin54
- Lin9
- Rbap48
- Rbbp4
- Rbl1
- Rbl2
- Tfdp1
- Tfdp2
- Tgs1
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G2 Phase
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- Ccna
- Ccna1
- Ccna2
- Cdk2
- Cdkn2
- Cyca
- Cyca2
- E2f1
- E2f3
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SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
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- Ccnc
- Ccnk
- Ccnt1
- Ccnt2
- Cdk8
- Cdk9
- Dp2
- Dpc4
- E2f4
- E2f5
- Erk1
- Erk2
- Fur
- Furin
- Madh2
- Madh3
- Madh4
- Madh7
- Madh8
- Madr2
- Mapk
- Mapk1
- Mapk3
- Men1
- Pcsk3
- Prkm1
- Prkm3
- Rbl1
- Rnf111
- Rps27a
- Smad2
- Smad3
- Smad4
- Smad7
- Sp1
- Taz
- Tfdp1
- Tfdp2
- Uba52
- Uba80
- Ubb
- Ubc
- Ubcep1
- Ubcep2
- Wwtr1
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RNA polymerase II transcribes snRNA genes
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- Cyclin-K
- Cyclin-T1
- Cyclin-T2
- Cyclin-dependent kinase 7
- Cyclin-dependent kinase 9
- DNA-directed RNA polymerase II subunit RPB11
- DNA-directed RNA polymerase II subunit RPB1
- DNA-directed RNA polymerase II subunit RPB2
- DNA-directed RNA polymerase II subunit RPB3
- DNA-directed RNA polymerase II subunit RPB4
- DNA-directed RNA polymerase II subunit RPB7
- DNA-directed RNA polymerase II subunit RPB9
- DNA-directed RNA polymerases I, II, and III subunit RPABC1
- DNA-directed RNA polymerases I, II, and III subunit RPABC2
- DNA-directed RNA polymerases I, II, and III subunit RPABC3
- DNA-directed RNA polymerases I, II, and III subunit RPABC4
- DNA-directed RNA polymerases I, II, and III subunit RPABC5
- General transcription factor IIE subunit 1
- General transcription factor IIE subunit 2
- General transcription factor IIF subunit 1
- General transcription factor IIF subunit 2
- Integrator complex subunit 10
- Integrator complex subunit 11
- Integrator complex subunit 12
- Integrator complex subunit 13
- Integrator complex subunit 14
- Integrator complex subunit 1
- Integrator complex subunit 2
- Integrator complex subunit 3
- Integrator complex subunit 4
- Integrator complex subunit 5
- Integrator complex subunit 6
- Integrator complex subunit 7
- Integrator complex subunit 8
- Integrator complex subunit 9
- Little elongation complex subunit 1
- Little elongation complex subunit 2
- Nuclear cap-binding protein subunit 1
- Nuclear cap-binding protein subunit 2
- POU domain, class 2, transcription factor 1
- POU domain, class 2, transcription factor 2
- Phosphorylated adapter RNA export protein
- Pre-mRNA cleavage complex 2 protein Pcf11
- Putative RNA polymerase II subunit B1 CTD phosphatase Rpap2
- RNA polymerase II elongation factor ELL2
- RNA polymerase II elongation factor ELL3
- RNA polymerase II elongation factor ELL
- RNA polymerase II subunit A C-terminal domain phosphatase SSU72
- Regulation of nuclear pre-mRNA domain-containing protein 1A
- Regulation of nuclear pre-mRNA domain-containing protein 1B
- Regulation of nuclear pre-mRNA domain-containing protein 2
- SOSS complex subunit B1
- SOSS complex subunit B2
- Serrate RNA effector molecule homolog
- TATA-box-binding protein
- Transcription elongation factor SPT4-A
- Transcription elongation factor SPT5
- Transcription factor Sp1
- Transcription initiation factor IIA subunit 1
- Transcription initiation factor IIA subunit 2
- Transcription initiation factor IIB
- Transcription initiation factor TFIID subunit 11
- Transcription initiation factor TFIID subunit 13
- Transcription initiation factor TFIID subunit 5
- Transcription initiation factor TFIID subunit 6
- Transcription initiation factor TFIID subunit 8
- Transcription initiation factor TFIID subunit 9
- Zinc finger CCCH domain-containing protein 8
- snRNA-activating protein complex subunit 1
- snRNA-activating protein complex subunit 2
- snRNA-activating protein complex subunit 3
- snRNA-activating protein complex subunit 4
- snRNA-activating protein complex subunit 5
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- Ars2
- Asr2
- Asun
- Cak
- Cbp20
- Cbp80
- Ccnk
- Ccnt1
- Ccnt2
- Cdk7
- Cdk9
- Cdkn7
- Cpsf3l
- Crept
- Crk4
- D14Ertd231e
- Dbi1
- Ddx26
- Ell
- Ell2
- Ell3
- Fliz1
- Gtf2a1
- Gtf2a2
- Gtf2b
- Gtf2e1
- Gtf2e2
- Gtf2f1
- Gtf2f2
- Ice1
- Ice2
- IntS13
- Ints1
- Ints10
- Ints11
- Ints12
- Ints14
- Ints2
- Ints3
- Ints4
- Ints5
- Ints6
- Ints7
- Ints8
- Ints9
- KIAA0824
- Kiaa0460
- Kiaa0947
- Kiaa1287
- Kiaa4077
- Mo15
- Mpk-7
- Mt1a
- Nabp1
- Nabp2
- Narg2
- Ncbp1
- Ncbp2
- Obfc2a
- Obfc2b
- Oct-1
- Oct2
- Otf-1
- Otf1
- Otf2
- P15rs
- Pcf11
- Phax
- Phf22
- Polr2a
- Polr2b
- Polr2c
- Polr2d
- Polr2e
- Polr2f
- Polr2g
- Polr2h
- Polr2i
- Polr2j
- Polr2k
- Polr2l
- Pou2f1
- Pou2f2
- Rnuxa
- Rpap2
- Rpii215
- Rpo2-1
- Rpo2-3
- Rpo2-4
- Rprd1a
- Rprd1b
- Rprd2
- Snapc1
- Snapc2
- Snapc3
- Snapc4
- Snapc5
- Sp1
- Spata30
- Spt4h
- Srrt
- Ssb1
- Ssb2
- Ssu72
- Supt4a
- Supt4h
- Supt4h1a
- Supt5
- Supt5h
- Taf11
- Taf13
- Taf2e
- Taf2g
- Taf2k
- Taf5
- Taf6
- Taf8
- Taf9
- Tbn
- Tbp
- Tfiid
- Vwa9
- Zc3h8
- Zc3hdc8
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MAPK3 (ERK1) activation
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- Cdc2
- Cdc2a
- Cdk1
- Cdkn1
- Erk1
- Il-6
- Il6
- Il6r
- Il6ra
- Il6st
- Jak1
- Jak2
- Map2k1
- Mapk3
- Mek1
- Prkm3
- Prkmk1
- Ptpn11
- Tyk2
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G2/M DNA replication checkpoint
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- Ccn-2
- Ccnb1
- Ccnb1-rs13
- Ccnb2
- Cdc2
- Cdc2a
- Cdk1
- Cdkn1
- Cycb
- Cycb1
- Cycb2
- Myt1
- Pkmyt1
- Wee1
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Activation of NIMA Kinases NEK9, NEK6, NEK7
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- Ccn-2
- Ccnb1
- Ccnb1-rs13
- Ccnb2
- Cdc2
- Cdc2a
- Cdk1
- Cdkn1
- Cycb
- Cycb1
- Cycb2
- Nek9
- Nercc
- Plk
- Plk1
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Mitotic Prophase
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- Ccn-2
- Ccnb1
- Ccnb1-rs13
- Cdc2
- Cdc2a
- Cdk1
- Cdkn1
- Cycb
- Cycb1
- Numa1
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PTK6 Regulates Cell Cycle
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- Ccnd1
- Ccne
- Ccne1
- Cdk2
- Cdk4
- Cdkn1b
- Cdkn2
- Crk3
- Cyl-1
- Ptk6
- Sik
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Drug-mediated inhibition of CDK4/CDK6 activity
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- Ccnd1
- Ccnd2
- Ccnd3
- Cdk4
- Cdk6
- Cdkn6
- Crk2
- Crk3
- Cyl-1
- Cyl-2
- Cyl-3
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