RAF/MAP kinase cascade
|
|
|
- ACTN2
- AFGF
- ANG1
- ANGPT1
- AREG
- ARTN
- BTC
- CALM
- CAMK2A
- CAMK2B
- CAMK2D
- CSF2
- CSF2RB
- DLG1
- DLG3
- DLG4
- EGFR
- EPGN
- ERBB2
- ERBB3
- ERBB4
- EREG
- ERK2
- FGF1
- FGF10
- FGF16
- FGF17
- FGF18
- FGF19
- FGF2
- FGF20
- FGF23
- FGF3
- FGF4
- FGF4A
- FGF4C
- FGF5
- FGF5B
- FGF5C
- FGF6
- FGF6A
- FGF7
- FGF7B
- FGF8
- FGF8A
- FGF9
- FGFA
- FGFR1
- FGFR2
- FGFR3
- FGFR4
- FLT3
- FLT3LG
- FRS2
- FRS3
- FYN
- Fgf4
- GDNF
- GFRA1
- GFRA2
- GFRA3
- GFRA4
- GRB2
- HBEGF
- HBGF-1
- HGF
- IL-2
- IL2
- IL2RA
- IL2RG
- IL3
- IL3RA
- IL5
- IL5RA
- IRS1
- IRS2
- JAK1
- JAK2
- JAK3
- KIT
- KITLG
- KL
- KLB
- KRAS
- LAT
- MAPK1
- MAPK3
- MET
- NEFL
- NRAPGEP
- NRAS
- NRG1
- NRG2
- NRG3
- NRTN
- ODAD3
- PDGFA
- PDGFB
- PDGFRA
- PDGFRB
- PDZGEF1
- PEA15
- PIK3CA
- PIK3CB
- PIK3R1
- PIK3R2
- PRKM1
- PTK2
- PTPRA
- RALGDS
- RANBP9
- RAPGEF2
- RASGEF1A
- RASGRF1
- RASGRF2
- RASGRP1
- RASGRP3
- RASGRP4
- RET
- RGL1
- RGL2
- RGL3
- SCF
- SHC1
- SHC2
- SHC3
- SOS1
- SPTA1
- SPTAN1
- SPTB
- SPTBN2
- SPTBN4
- TEK
- TGFA
- TIE-2
- TIE2
|
|
MHC class II antigen presentation
|
- ADP-ribosylation factor 1
- AP complex subunit beta
- AP complex subunit sigma
- AP-1 complex subunit beta-1
- AP-1 complex subunit gamma
- AP-1 complex subunit mu-1
- AP-1 complex subunit mu-2
- AP-1 complex subunit sigma-1A
- AP-1 complex subunit sigma-2
- AP-2 complex subunit alpha-2
- AP-2 complex subunit alpha
- AP-2 complex subunit mu
- AP-2 complex subunit sigma
- Actin-related protein 10
- Alpha-centractin
- BOLA-DQA1 protein
- Beta-centractin
- BoLA-DR-alpha
- CD74 molecule
- Calnexin
- Carboxypeptidase
- Cathepsin B
- Cathepsin D
- Cathepsin F
- Cathepsin K
- Cathepsin O
- Cathepsin S
- Centromere protein E
- Clathrin heavy chain 1
- Clathrin light chain A
- Cytoplasmic dynein 1 intermediate chain 1
- Dipeptidyl peptidase 1
- Dynactin subunit 1
- Dynactin subunit 2
- Dynactin subunit 3
- Dynactin subunit 4
- Dynactin subunit 5
- Dynactin subunit 6
- Dynamin-1
- Dynein cytoplasmic 1 heavy chain 1
- Dynein light chain 1, cytoplasmic
- Dynein light chain 2, cytoplasmic
- Dynein light intermediate chain
- Dynein light intermediate chain
- F-actin-capping protein subunit alpha-1
- F-actin-capping protein subunit alpha-2
- F-actin-capping protein subunit alpha
- Gamma-interferon-inducible lysosomal thiol reductase
- Ig-like domain-containing protein
- Ig-like domain-containing protein
- Ig-like domain-containing protein
- Ig-like domain-containing protein
- Kinesin family member 11
- Kinesin family member 15
- Kinesin family member 23
- Kinesin family member 5A
- Kinesin light chain
- Kinesin light chain
- Kinesin light chain
- Kinesin light chain
- Kinesin-like protein KIF20A
- Kinesin-like protein
- Kinesin-like protein
- Kinesin-like protein
- Kinesin-like protein
- Legumain
- Lymphocyte activating 3
- MHC class II DO-beta chain
- MHC class II antigen
- MHC class II antigen
- MHC class II antigen
- Major histocompatibility complex, class II, DM alpha
- Major histocompatibility complex, class II, DO alpha
- Major histocompatibility complex, class II, DQ alpha 5
- Major histocompatibility complex, class II, DY alpha
- Oxysterol-binding protein
- Pro-cathepsin H
- Procathepsin L
- Protein SEC13 homolog
- Protein transport protein SEC23
- Protein transport protein Sec24A
- Protein transport protein Sec31A
- Rab interacting lysosomal protein
- Rac GTPase activating protein 1
- SEC24 homolog B, COPII coat complex component
- SEC24 homolog C, COPII coat complex component
- SEC24 homolog D, COPII coat complex component
- SH3 domain containing GRB2 like 2, endophilin A1
- Small COPII coat GTPase SAR1B
- Spectrin beta chain
- dynamin GTPase
|
|
- ACTR10
- ACTR1A
- ACTR1B
- AP1B1
- AP1G1
- AP1M1
- AP1M2
- AP1S1
- AP1S2
- AP1S3
- AP2A1
- AP2A2
- AP2B1
- AP2M1
- AP2S1
- ARF1
- ARP10
- BLA-DQB
- BOLA-DMA
- BOLA-DMB
- BOLA-DOA
- BOLA-DQA1
- BOLA-DQA2
- BOLA-DQA5
- BOLA-DRA
- BOLA-DRB2
- BOLA-DRB3
- BOLA-DYA
- BOLA-DYB
- BoLA-DIB
- BoLA-DOB
- BoLA-DRA
- BoLA-DYB
- CANX
- CAPZA1
- CAPZA2
- CAPZA3
- CD74
- CENPE
- CLTA
- CLTC
- CTSA
- CTSB
- CTSC
- CTSD
- CTSF
- CTSH
- CTSK
- CTSL
- CTSL1
- CTSO
- CTSS
- DCTN1
- DCTN2
- DCTN3
- DCTN4
- DCTN5
- DCTN6
- DMB
- DNCL1
- DNM1
- DNM3
- DYB
- DYNC1H1
- DYNC1I1
- DYNC1LI1
- DYNC1LI2
- DYNLL1
- DYNLL2
- HLA-DMB
- HLA-DRA
- IFI30
- KIF11
- KIF15
- KIF20A
- KIF22
- KIF23
- KIF2B
- KIF3A
- KIF5A
- KIF5B
- KLC1
- KLC2
- KLC3
- KLC4
- LAG3
- LGMN
- LOC100848815
- OSBPL1A
- RACGAP1
- RILP
- SAR1B
- SEC13
- SEC13L1
- SEC23A
- SEC24A
- SEC24B
- SEC24C
- SEC24D
- SEC31A
- SH3GL2
- SPTBN2
- canx
|
|
COPI-independent Golgi-to-ER retrograde traffic
|
|
|
- ACTR10
- ACTR1A
- AGPAT3
- ARP10
- BICD1
- BICD2
- CAPZA1
- CAPZA2
- CAPZA3
- CPLA2
- DCTN1
- DCTN2
- DCTN3
- DCTN4
- DCTN5
- DCTN6
- DNCL1
- DYNC1H1
- DYNC1I1
- DYNC1LI1
- DYNC1LI2
- DYNLL1
- DYNLL2
- GALNT1
- GALNT2
- LIS1
- PAFAH1B1
- PAFAH1B2P68402
- PAFAH1B3
- PAFAHB
- PAFAHG
- PLA2G4
- PLA2G4A
- PLA2G6
- RAB18
- RAB3GAP1
- RAB3GAP2
- RAB6A
- RAB6B
|
|
HSP90 chaperone cycle for SHRs
|
|
|
- ACTR10
- ACTR1A
- AR
- ARP10
- CAPZA1
- CAPZA2
- CAPZA3
- DCTN1
- DCTN2
- DCTN3
- DCTN4
- DCTN5
- DCTN6
- DNAJA1
- DNAJA2
- DNAJA4
- DNAJB1
- DNCL1
- DYNC1H1
- DYNC1I1
- DYNC1LI1
- DYNC1LI2
- DYNLL1
- DYNLL2
- FKBP4
- FKBP5
- HSC70
- HSP70-1
- HSP90A
- HSP90AA1
- HSP90AB1
- HSPA1A
- HSPA1L
- HSPA2
- HSPA8
- HSPC3
- HSPCA
- HSPCB
- NR3C1
- NR3C2
- PGR
- PTGES3
- STIP1
|
|
COPI-mediated anterograde transport
|
|
|
- ACTR10
- ACTR1A
- ARCN1
- ARF1
- ARF3
- ARF4
- ARF5
- ARFGAP1
- ARFGAP2
- ARFGAP3
- ARP10
- BET1
- BET1L
- CAPZA1
- CAPZA2
- CAPZA3
- CD55
- CD59
- COG1
- COG2
- COG3
- COG4
- COG5
- COG6
- COG7
- COG8
- COPA
- COPB1
- COPB2
- COPD
- COPE
- COPE1
- COPG1
- COPG2
- COPZ
- COPZ1
- COPZ2
- DCTN1
- DCTN2
- DCTN3
- DCTN4
- DCTN5
- DCTN6
- DNCL1
- DYNC1H1
- DYNC1I1
- DYNC1LI1
- DYNC1LI2
- DYNLL1
- DYNLL2
- FOLR3
- GBF1
- GOLGA2
- GOLGB1
- GORASP1
- GOSR1
- GOSR2
- INS
- KDELR
- KDELR1
- KDELR2
- KDELR3
- NAPA
- NAPB
- NAPG
- NSF
- RAB1A
- RAB1B
- SNAPB
- SPTA1
- SPTAN1
- SPTB
- SPTBN2
- SPTBN4
- STX5
- TMED10
- TMED3
- TMED7
- TMED9
- TMEM115
- TMP21
- USO1
- VDP
- YKT6
|
|
Signaling by Activin
|
|
|
- ACTRII
- ACVR1B
- ACVR1C
- ACVR2
- ACVR2A
- ACVR2B
- ERK2
- INHA
- INHBA
- INHBB
- MAPK1
- MAPK3
- PRKM1
- SMAD2
- SMAD3
- SMAD4
- TGFBR3
|
|
Signaling by BMP
|
|
|
- ACTRII
- ACVR2
- ACVR2A
- ACVR2B
- ACVRL1
- AMH
- AMHR2
- BMP10
- BMP2
- BMPR1A
- BMPR1B
- BMPR2
- CER1
- CHRDL1
- FSTL1
- GDF2
- INHA
- INHBA
- NOG
- SF3A2
- SKI
- SMAD1
- SMAD4
- SMAD5
- SMAD6
- SMAD7
- SMAD9
- SMURF1
- SMURF2
- TGFBR3
- UBE2D1
- UBE2D3
- ZFYVE16
|
|
Aflatoxin activation and detoxification
|
|
|
- ACY1
- AKR7A2
- CYP1A2
- CYP2A13
- CYP3A28
- CYP3A4
- CYP3A5
- CYP3A74
- CYP3A76
- DPEP1
- DPEP2
- DPEP3
- GGT1
- GGT5
- GGT7
- GGTL3
- MGST1
- MGST2
- MGST3
|
|
Nuclear Receptor transcription pathway
|
|
|
- AD4BP
- AR
- ESR
- ESR1
- ESR2
- ESRRA
- ESRRB
- ESRRG
- FTZF1
- HNF4A
- HNF4G
- LXRA
- LXRB
- MED1
- NCOR1
- NCOR2
- NR0B1
- NR0B2
- NR1C3
- NR1D1
- NR1D2
- NR1H2
- NR1H3
- NR1H4
- NR1I2
- NR1I3
- NR2B3
- NR2C1
- NR2C2
- NR2E1
- NR2E3
- NR2F1
- NR2F6
- NR3A1
- NR3A2
- NR3C1
- NR3C2
- NR4A1
- NR4A2
- NR4A3
- NR5A1
- NR5A2
- NR6A1
- NRBF2
- PGR
- PPARA
- PPARD
- PPARG
- RARA
- RARB
- RARG
- RORC
- RXRA
- RXRB
- RXRG
- TFCOUP1
- THRA
- THRB
- VDR
|
|
SUMOylation of intracellular receptors
|
|
|
- AD4BP
- AR
- ESR
- ESR1
- FTZF1
- HDAC4
- LXRA
- LXRB
- NR1H2
- NR1H3
- NR1H4
- NR1I2
- NR3A1
- NR3C1
- NR3C2
- NR5A1
- NR5A2
- PGR
- PIAS1
- PIAS2
- PIAS3
- PIAS4
- PPARA
- RARA
- RXRA
- SMT3B
- SUMO2
- SUMO3
- THRA
- THRB
- VDR
|
|
Ub-specific processing proteases
|
|
|
- ADA3
- ADRB2
- ADRM1
- AR
- ARHT1
- ARRB1
- ARRB2
- ATXN7
- AXIN1
- AXIN2
- BECN1
- BIRC2
- BIRC3
- BIT1
- CCNA1
- CCNA2
- CCP110
- CDC20
- CDC25A
- CLSPN
- CYLD
- CYLD1
- DDB2
- FKBP8
- FOXO4
- GATA3
- H2AC10
- H2AC12
- H2AC18
- H2AC21
- H2AC25
- H2AC6
- H2AW
- H2B
- H2BC26
- H2BC5
- HGS
- HIF1A
- HIST1H2BI
- HIST3H2A
- IDE
- IFIH1
- IKBKG
- IL33
- KAT2A
- KEAP1
- LOC112446467
- LOC614881
- LOC790134
- MAP3K7
- MAT2B
- MDM2
- MUL1
- MYC
- NEMO
- NFKBIA
- OTUB1
- POLB
- PSMA1
- PSMA2
- PSMA3
- PSMA4
- PSMA5
- PSMA6
- PSMA7
- PSMA8
- PSMB1
- PSMB10
- PSMB2
- PSMB3
- PSMB4
- PSMB5
- PSMB6
- PSMB7
- PSMB8
- PSMB9
- PSMC2
- PSMC3
- PSMC4
- PSMC5
- PSMC6
- PSMD1
- PSMD11
- PSMD12
- PSMD13
- PSMD14
- PSMD2
- PSMD3
- PSMD4
- PSMD5
- PSMD6
- PSMD7
- PSMD8
- PSMD9
- PSME1
- PSME2
- PSME4
- PSMF1
- PTEN
- PTRH2
- RCE1
- RHOT1
- RIGI
- RIPK1
- RNF123
- RNF128
- RNF146B
- RPS27A
- RUVBL1
- SIAH2
- SKP2
- SMAD1
- SMAD2
- SMAD3
- SMAD4
- SMAD7
- SMURF2
- STAM2
- SUG1
- TAB1
- TADA2B
- TADA3
- TADA3L
- TAF10
- TAF9B
- TGFBR1
- TNKS
- TNKS2
- TOMM20
- TOMM70
- TOMM70A
- TP53
- TRAF2
- TRAF6
- TRAP2
- TRRAP
- Tom70
- UBA52
- UBA80
- UBB
- UBC
- UBCEP1
- UBCEP2
- UFC1
- UFD1
- USP11
- USP12
- USP13
- USP14
- USP15
- USP19
- USP20
- USP21
- USP22
- USP24
- USP25
- USP26
- USP28
- USP3
- USP30
- USP33
- USP34
- USP37
- USP4
- USP42
- USP44
- USP47
- USP48
- USP49
- USP5
- USP7
- USP8
- USP9X
- VDAC1
- VDAC2
- VDAC3
- VDAC5P
- WDR20
- WDR48
- bIkBa
|
|
Regulation of IGF Activity by IGFBP
|
|
|
- ADAM10
- AFP
- AHSG
- ALB
- AMBN
- AMELX
- AMTN
- ANO8
- APOA1
- APOA2
- APOA5
- APOB
- APOE
- APOL3
- APP
- BMP15
- BMP4
- BPIFB2
- C3
- C4A
- CALU
- CCN1
- CDH2
- CHGB
- CHGC
- CHRDL1
- CKAP4
- CP
- CSF1
- CSPG2
- CST3
- DMP1
- DNAJC3
- ENAM
- F5
- FAM20A
- FAM20C
- FBN1
- FETUA
- FGA
- FGF23
- FN1
- FSTL1
- FUCA2
- GAS6
- GOLM1
- GPC3
- GRP94
- HRC
- HSP90B1
- HSPC4
- IGF1
- IGF2
- IGFBP1
- IGFBP2
- IGFBP3
- IGFBP4
- IGFBP5
- IGFBP7
- IL6
- ITIH2
- KNG1
- KTN1
- LGALS1
- LOC107131209
- LOC112442231
- LOC112446726
- LOC510193
- LOC515697
- LOC518495
- LOC521214
- LOC524576
- LOC531557
- LOC786352
- LOC788334
- LTBP1
- MADM
- MATN3
- MBTPS1
- MEGF6
- MELTF
- MEN1
- MEPE
- MFGE8
- MGAT4A
- MIA3
- MXRA8
- NUCB1
- P4HB
- PAPPA2
- PDIA6
- PENK
- PI
- PNPLA2
- PRKCSH
- PROC
- PRSS23
- RCN1
- SCG2
- SCG3
- SCOTIN
- SDC2
- SERPINA1
- SERPINA10
- SERPIND1
- SHISA5
- SPARCL1
- SPP1
- SPP2
- SPP24
- STC2
- TF
- TMEM132A
- TNC
- TRA1
- VCAN
- VGF
- VWA1
- WFS1
|
|
Post-translational protein phosphorylation
|
|
|
- ADAM10
- AFP
- AHSG
- ALB
- AMBN
- AMELX
- AMTN
- ANO8
- APOA1
- APOA2
- APOA5
- APOB
- APOE
- APOL3
- APP
- BMP15
- BMP4
- BPIFB2
- C3
- C4A
- CALU
- CCN1
- CDH2
- CHGB
- CHGC
- CHRDL1
- CKAP4
- CP
- CSF1
- CSPG2
- CST3
- DMP1
- DNAJC3
- ENAM
- F5
- FAM20A
- FAM20C
- FBN1
- FETUA
- FGA
- FGF23
- FN1
- FSTL1
- FUCA2
- GAS6
- GOLM1
- GPC3
- GRP94
- HRC
- HSP90B1
- HSPC4
- IGFBP1
- IGFBP3
- IGFBP4
- IGFBP5
- IGFBP7
- IL6
- ITIH2
- KNG1
- KTN1
- LGALS1
- LOC107131209
- LOC112442231
- LOC112446726
- LOC510193
- LOC515697
- LOC518495
- LOC521214
- LOC524576
- LOC531557
- LOC786352
- LOC788334
- LTBP1
- MADM
- MATN3
- MBTPS1
- MEGF6
- MELTF
- MEN1
- MEPE
- MFGE8
- MGAT4A
- MIA3
- MXRA8
- NUCB1
- P4HB
- PDIA6
- PENK
- PI
- PNPLA2
- PRKCSH
- PROC
- PRSS23
- RCN1
- SCG2
- SCG3
- SCOTIN
- SDC2
- SERPINA1
- SERPINA10
- SERPIND1
- SHISA5
- SPARCL1
- SPP1
- SPP2
- SPP24
- STC2
- TF
- TMEM132A
- TNC
- TRA1
- VCAN
- VGF
- VWA1
- WFS1
|
|
Regulated proteolysis of p75NTR
|
|
|
- ADAM17
- APH1A
- APH1B
- NCSTN
- NFKB1
- NGFR
- PEN2
- PSEN1
- PSEN2
- PSENEN
- RELA
- TRAF6
|
|
Regulation of CDH11 function
|
|
|
- ADAM19
- ADAM33
- AMOT
- ANGPTL4
- CDH11
- CTNNB1
- CTNND1
- JUP
|
|
Interaction With Cumulus Cells And The Zona Pellucida
|
|
|
- ADAM2
- B4GALT1
- GALT
- GGTB2
- LOC509761
- OVGP1
- ZP2
- ZP3
- ZP4
- ZPB
|
|
LGI-ADAM interactions
|
|
|
- ADAM22
- ADAM23
- CACNG2
- CACNG3
- CACNG4
- CACNG8
- DLG4
- LGI1
- LGI2
- LGI3
- LGI4
- STX1A
- STX1B
- STX1B2
|
|
O-glycosylation of TSR domain-containing proteins
|
|
|
- ADAMTS1
- ADAMTS10
- ADAMTS12
- ADAMTS13
- ADAMTS14
- ADAMTS15
- ADAMTS16
- ADAMTS17
- ADAMTS18
- ADAMTS19
- ADAMTS2
- ADAMTS20
- ADAMTS3
- ADAMTS4
- ADAMTS5
- ADAMTS6
- ADAMTS8
- ADAMTS9
- ADAMTSL1
- ADAMTSL3
- ADAMTSL4
- ADAMTSL5
- B3GLCT
- CFP
- NPI
- POFUT2
- RPESP
- SBSPON
- SEMA5A
- SEMA5B
- SPON1
- SSPO
- THBS1
- THBS2
- THSD1
- THSD7A
- THSD7B
- VSGP
|
|
Collagen biosynthesis and modifying enzymes
|
|
|
- ADAMTS14
- ADAMTS2
- ADAMTS3
- BMP1
- COL10A1
- COL11A1
- COL11A2
- COL12A1
- COL13A1
- COL14A1
- COL16A1
- COL17A1
- COL18A1
- COL1A1
- COL1A2
- COL20A1
- COL23A1
- COL26A1
- COL27A1
- COL28A1
- COL2A1
- COL3A1
- COL4A1
- COL4A3
- COL4A5
- COL4A6
- COL5A1
- COL5A3
- COL6A1
- COL6A2
- COL6A3
- COL6A5
- COL6A6
- COL8A1
- COL8A2
- COLGALT1
- COLGALT2
- GLT25D1
- LEPREL1
- NPI
- P3H2
- P3H3
- P4HA1
- P4HA2
- P4HA3
- P4HB
- PCOLCE
- PCOLCE2
- PLOD1
- PLOD2
- PLOD3
- SERPINH1
- TLL1
- TLL2
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Ubiquinol biosynthesis
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- ADCK3
- CABC1
- COQ2
- COQ3
- COQ4
- COQ5
- COQ6
- COQ7
- COQ8A
- COQ9
- PDSS1
- PDSS2
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G alpha (z) signalling events
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- ADCY1
- ADCY2
- ADCY3
- ADCY4
- ADCY5
- ADCY6
- ADCY8
- ADCY9
- ADRA2A
- ADRA2B
- ADRA2C
- GNAZ
- GNB1
- GNB2
- GNB3
- GNB4
- GNB5
- GNG10
- GNG11
- GNG12
- GNG13
- GNG2
- GNG3
- GNG4
- GNG5
- GNG7
- GNG8
- GNGT1
- GNGT12
- GNGT2
- GNGT3
- GNGT5
- GNGT7
- GNGT8
- RGS16
- RGS17
- RGS20
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PKA activation
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- ADCY1
- ADCY2
- ADCY3
- ADCY4
- ADCY5
- ADCY6
- ADCY8
- ADCY9
- CALM
- PRKACA
- PRKACB
- PRKAR1A
- PRKAR1B
- PRKAR2A
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Hedgehog 'off' state
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- ADCY1
- ADCY2
- ADCY3
- ADCY4
- ADCY5
- ADCY6
- ADCY8
- ADCY9
- FUZ
- GLI1
- GLI2
- GLI3
- GPR161
- IFT122
- IFT140
- IFT52
- IFT57
- IFT88
- INTU
- KIF3A
- KIF7
- OFD1
- PDZD6
- PRKACA
- PRKACB
- PRKAR1A
- PRKAR1B
- PRKAR2A
- PTCH1
- RPGRIP1L
- SMO
- SUFU
- TTC21B
- TULP3
- WDR19
- WDR35
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Adenylate cyclase inhibitory pathway
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- ADCY1
- ADCY2
- ADCY3
- ADCY4
- ADCY5
- ADCY6
- ADCY8
- ADCY9
- GNAI1
- GNAI2
- GNAI3
- GNAL
- GNAT3
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Adenylate cyclase activating pathway
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|
- ADCY1
- ADCY2
- ADCY3
- ADCY4
- ADCY5
- ADCY6
- ADCY8
- ADCY9
- GNAL
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