GlyCosmos Portal

Bos taurus (domestic cattle)

Summary

Taxonomy ID: 9913
PubChem Taxonomy: 9913

Genes (2200) Glycans (1011) Glycoproteins (1220) Lectins (76) Pathways (548)

Displaying entries **76 - 100** of **548** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol ▲
Signaling by Activin	Activin receptor type-2A Inhibin alpha chain Inhibin beta A chain Inhibin beta B chain Mitogen-activated protein kinase 1 Mitogen-activated protein kinase Mothers against decapentaplegic homolog Mothers against decapentaplegic homolog Mothers against decapentaplegic homolog Serine/threonine-protein kinase receptor Transforming growth factor beta receptor 3 receptor protein serine/threonine kinase receptor protein serine/threonine kinase	A0A3Q1LMU4 A0A3Q1MGJ6 B0JYL0 E1B8P9 E1B9H5 E1BE92 F1MMW7 F1MSQ2 F1MUZ3 P07994 P07995 P46196 Q28043	ACTRII ACVR1B ACVR1C ACVR2 ACVR2A ACVR2B ERK2 INHA INHBA INHBB MAPK1 MAPK3 PRKM1 SMAD2 SMAD3 SMAD4 TGFBR3
Signaling by BMP	Activin receptor type-2A Anti-Muellerian hormone type-2 receptor Bone morphogenetic protein 2 Bone morphotic protein 10 Cerberus 1, DAN family BMP antagonist Chordin like 1 E3 ubiquitin-protein ligase E3 ubiquitin-protein ligase Follistatin-related protein 1 Growth differentiation factor 2 Inhibin alpha chain Inhibin beta A chain Mothers against decapentaplegic homolog 1 Mothers against decapentaplegic homolog Mothers against decapentaplegic homolog Mothers against decapentaplegic homolog Mothers against decapentaplegic homolog Muellerian-inhibiting factor Noggin SMAD family member 7 Serine/threonine-protein kinase receptor Serine/threonine-protein kinase receptor Ski oncogene Transforming growth factor beta receptor 3 Ubiquitin conjugating enzyme E2 D3 Ubiquitin-conjugating enzyme E2 D1 Zinc finger FYVE-type containing 16 receptor protein serine/threonine kinase receptor protein serine/threonine kinase receptor protein serine/threonine kinase	A0A3Q1LJ39 A0A3Q1LP90 A0A3Q1LSA1 A0A3Q1M3K3 A0A3Q1M5N0 A0A3Q1MGJ6 A5PJI9 B0JYL0 E1B8T7 E1B8X7 E1B9H5 E1BBN3 E1BEG4 E1BG11 E1BH37 E1BHR7 E1BN54 F1MAZ4 F1MCE7 F1MIW7 F1MLS5 F1MZL1 F1N727 G3N3L0 P07994 P07995 Q1JQA2 Q28043 Q2TA10 Q58D84	ACTRII ACVR2 ACVR2A ACVR2B ACVRL1 AMH AMHR2 BMP10 BMP2 BMPR1A BMPR1B BMPR2 CER1 CHRDL1 FSTL1 GDF2 INHA INHBA NOG SF3A2 SKI SMAD1 SMAD4 SMAD5 SMAD6 SMAD7 SMAD9 SMURF1 SMURF2 TGFBR3 UBE2D1 UBE2D3 ZFYVE16
TGFBR3 regulates activin signaling	Activin receptor type-2A Inhibin alpha chain Inhibin beta A chain Transforming growth factor beta receptor 3	E1B9H5 P07994 P07995 Q28043	ACTRII ACVR2 ACVR2A INHA INHBA TGFBR3
Aflatoxin activation and detoxification	Cytochrome P450 1A Cytochrome P450 3A Cytochrome P450 3A Cytochrome P450 3A Cytochrome P450 3A Cytochrome P450 family 2 subfamily A member 13 Dipeptidase 1 Dipeptidase Glutathione S-transferase 3, mitochondrial Glutathione hydrolase 7 Glutathione hydrolase Glutathione hydrolase Microsomal glutathione S-transferase 1 Microsomal glutathione S-transferase 2 N-acyl-aliphatic-L-amino acid amidohydrolase NADP-dependent oxidoreductase domain-containing protein NADP-dependent oxidoreductase domain-containing protein	A0A3Q1LZ03 E1BIR2 F1MHN9 F1MR63 F1MXY2 F1MYJ3 F1MZC0 F1N6I4 G3MYH2 G3N2D8 G3X6I4 Q0V8L2 Q29RV2 Q2KJG4 Q3SZM7 Q3T047 Q3T100	ACY1 AKR7A2 CYP1A2 CYP2A13 CYP3A28 CYP3A4 CYP3A5 CYP3A74 DPEP1 DPEP2 GGT1 GGT5 GGT7 GGTL3 MGST1 MGST2 MGST3
Nuclear Receptor transcription pathway	Androgen receptor COUP transcription factor 1 Estrogen receptor beta Estrogen receptor Estrogen related receptor alpha Estrogen related receptor beta Estrogen related receptor gamma Glucocorticoid receptor Hepatocyte nuclear factor 4 gamma Hepatocyte nuclear factor 4alpha Mediator of RNA polymerase II transcription subunit 1 Mineralocorticoid receptor NR1I2 protein Nuclear receptor binding factor 2 Nuclear receptor corepressor 1 Nuclear receptor corepressor 2 Nuclear receptor subfamily 0 group B member 1 Nuclear receptor subfamily 0 group B member 2 Nuclear receptor subfamily 1 group D member 1 Nuclear receptor subfamily 1 group D member 2 Nuclear receptor subfamily 1 group H member 4 Nuclear receptor subfamily 1 group I member 3 Nuclear receptor subfamily 2 group C member 1 Nuclear receptor subfamily 2 group C member 2 Nuclear receptor subfamily 2 group E member 1 Nuclear receptor subfamily 2 group E member 3 Nuclear receptor subfamily 2 group F member 6 Nuclear receptor subfamily 4 group A member 1 Nuclear receptor subfamily 4 group A member 2 Nuclear receptor subfamily 4 group A member 3 Nuclear receptor subfamily 5 group A member 2 Nuclear receptor subfamily 6 group A member 1 Oxysterols receptor LXR-alpha Oxysterols receptor LXR-beta PPARD protein Peroxisome proliferator-activated receptor alpha Peroxisome proliferator-activated receptor gamma Progesterone receptor RAR related orphan receptor C RARG protein Retinoic acid receptor RXR-gamma Retinoic acid receptor RXR Retinoic acid receptor alpha Retinoic acid receptor beta Retinoid X receptor, beta Steroidogenic factor 1 Thyroid hormone receptor alpha Thyroid hormone receptor beta Vitamin D3 receptor	A0A3Q1LZI4 A0A3Q1LZU3 A0A3Q1M3W3 A0A3Q1M5G9 A0A3Q1MM20 A0A3Q1MY21 A0A3Q1N5N2 A0A3Q1N8R7 A0A3S5ZPB3 A2VDU4 A4IFL4 A6H7I6 E1B7Q6 E1B7S6 E1BML7 F1MBX3 F1MGG2 F1MGM4 F1ML62 F1MN19 F1MN68 F1MTT1 F1MWI2 F1MWQ3 F1MX52 F1MXG9 F1N0I2 F1N2B6 F1N3S3 F1N712 G3X6X1 G3X7C1 G5E5I7 G5E5J5 O18971 P49884 Q04752 Q08DD4 Q08DG0 Q08E02 Q08E53 Q0V8F0 Q0VC20 Q5BIS6 Q5E9B6 Q5EA13 Q7YRQ5 Q9TTR8 Q9XSB5	AD4BP AR ESR ESR1 ESR2 ESRRA ESRRB ESRRG FTZF1 HNF4A HNF4G LXRA LXRB MED1 NCOR1 NCOR2 NR0B1 NR0B2 NR1C3 NR1D1 NR1D2 NR1H2 NR1H3 NR1H4 NR1I2 NR1I3 NR2B3 NR2C1 NR2C2 NR2E1 NR2E3 NR2F1 NR2F6 NR3A1 NR3A2 NR3C1 NR3C2 NR4A1 NR4A2 NR4A3 NR5A1 NR5A2 NR6A1 NRBF2 PGR PPARA PPARD PPARG RARA RARB RARG RORC RXRA RXRB RXRG TFCOUP1 THRA THRB VDR
SUMOylation of intracellular receptors	Androgen receptor Estrogen receptor Glucocorticoid receptor Histone deacetylase Mineralocorticoid receptor NR1I2 protein Nuclear receptor subfamily 1 group H member 4 Nuclear receptor subfamily 5 group A member 2 Oxysterols receptor LXR-alpha Oxysterols receptor LXR-beta PIAS3 protein PIAS4 protein Peroxisome proliferator-activated receptor alpha Progesterone receptor Protein inhibitor of activated STAT 1 Protein inhibitor of activated STAT 2 Retinoic acid receptor RXR Retinoic acid receptor alpha SUMO-conjugating enzyme UBC9 Small ubiquitin-related modifier 1 Small ubiquitin-related modifier 2 Small ubiquitin-related modifier 3 Small ubiquitin-related modifier Steroidogenic factor 1 Thyroid hormone receptor alpha Thyroid hormone receptor beta Vitamin D3 receptor	A0A3Q1LPE8 A0A3Q1LUL4 A0A3Q1M2W5 A0A3Q1M5G9 A0A3Q1ML58 A0A3Q1N5N2 A0A3Q1N8R7 A2VDU4 A4FV15 A6QQU9 F1MN19 F1MTT1 F1MWQ3 F1MX52 F1MYR0 F1N2B6 F1N712 G3MZL6 G3X7C1 G5E5J5 P49884 P61955 Q04752 Q17QV3 Q5BIS6 Q5E9B6 Q5EA13	AD4BP AR ESR ESR1 FTZF1 HDAC4 LOC101906855 LXRA LXRB NR1H2 NR1H3 NR1H4 NR1I2 NR3A1 NR3C1 NR3C2 NR5A1 NR5A2 PGR PIAS1 PIAS2 PIAS3 PIAS4 PPARA RARA RXRA SMT3B SUMO2 SUMO3 THRA THRB VDR
Ub-specific processing proteases	26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome non-ATPase regulatory subunit 8 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 Androgen receptor Ataxin 7 Axin 2 Axin-1 Baculoviral IAP repeat containing 2 Baculoviral IAP repeat-containing 3 Beclin-1 Beta-2 adrenergic receptor Beta-arrestin-1 Beta-arrestin-2 CAAX prenyl protease 2 Cell division cycle 20 Cellular tumor antigen p53 Centriolar coiled-coil protein 110 Claspin Cyclin-A1 Cyclin-A2 DNA damage-binding protein 2 DNA polymerase beta E3 ubiquitin-protein ligase Mdm2 E3 ubiquitin-protein ligase RNF146-B E3 ubiquitin-protein ligase E3 ubiquitin-protein ligase FOXO4 protein GATA binding protein 3 Hepatocyte growth factor-regulated tyrosine kinase substrate Histone H2A type 1 Histone H2A/H2B/H3 domain-containing protein Histone H2A/H2B/H3 domain-containing protein Histone H2A/H2B/H3 domain-containing protein Histone H2A/H2B/H3 domain-containing protein Histone H2A Histone H2A Histone H2A Histone H2A Histone H2A Histone H2A Histone H2A Histone H2B type 1 Histone H2B Histone H2B Histone H2B Histone H2B Histone H2B Hypoxia-inducible factor 1-alpha Insulin-degrading enzyme Interleukin-33 Kelch-like ECH-associated protein 1 M-phase inducer phosphatase 1 Methionine adenosyltransferase 2 subunit beta Mitochondrial Rho GTPase 1 Mitochondrial import receptor subunit TOM20 homolog Mitogen-activated protein kinase kinase kinase 7 Mothers against decapentaplegic homolog 1 Mothers against decapentaplegic homolog Mothers against decapentaplegic homolog Mothers against decapentaplegic homolog Myc proto-oncogene protein NF-kappa-B essential modulator NF-kappa-B inhibitor alpha (Fragment) Non-selective voltage-gated ion channel VDAC1 Peptidyl-tRNA hydrolase 2, mitochondrial Phosphatase and tensin homolog Poly [ADP-ribose] polymerase Poly [ADP-ribose] polymerase Polyubiquitin-B Polyubiquitin-C Proteasomal ubiquitin receptor ADRM1 Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 14 Proteasome 26S subunit, ATPase 3 Proteasome 26S subunit, ATPase 6 Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta Proteasome subunit beta RING-type E3 ubiquitin transferase RING-type E3 ubiquitin transferase RNA helicase RNA helicase Receptor (TNFRSF)-interacting serine-threonine kinase 1 Ring finger protein 128 RuvB-like helicase SKP2 protein SMAD family member 7 Signal transducing adaptor molecule 2 TATA-box binding protein associated factor 9b TGF-beta activated kinase 1 (MAP3K7) binding protein 1 TGF-beta receptor type-1 TNF receptor-associated factor 6 TNF receptor-associated factor Transcription initiation factor TFIID subunit 10 Transcriptional adapter 3 Transcriptional adapter Transformation/transcription domain associated protein Translocase of outer mitochondrial membrane 70 Ubiquitin carboxyl-terminal hydrolase 12 Ubiquitin carboxyl-terminal hydrolase 13 Ubiquitin carboxyl-terminal hydrolase 14 Ubiquitin carboxyl-terminal hydrolase 15 Ubiquitin carboxyl-terminal hydrolase 20 Ubiquitin carboxyl-terminal hydrolase 22 Ubiquitin carboxyl-terminal hydrolase 33 Ubiquitin carboxyl-terminal hydrolase 37 Ubiquitin carboxyl-terminal hydrolase 47 Ubiquitin carboxyl-terminal hydrolase 48 Ubiquitin carboxyl-terminal hydrolase 4 Ubiquitin carboxyl-terminal hydrolase 7 Ubiquitin carboxyl-terminal hydrolase CYLD Ubiquitin carboxyl-terminal hydrolase Ubiquitin carboxyl-terminal hydrolase Ubiquitin carboxyl-terminal hydrolase Ubiquitin carboxyl-terminal hydrolase Ubiquitin carboxyl-terminal hydrolase Ubiquitin carboxyl-terminal hydrolase Ubiquitin carboxyl-terminal hydrolase Ubiquitin carboxyl-terminal hydrolase Ubiquitin carboxyl-terminal hydrolase Ubiquitin carboxyl-terminal hydrolase Ubiquitin carboxyl-terminal hydrolase Ubiquitin recognition factor in ER associated degradation 1 Ubiquitin specific peptidase 24 Ubiquitin specific peptidase 34 Ubiquitin specific peptidase 42 Ubiquitin thioesterase Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein Voltage-dependent anion-selective channel protein 2 Voltage-dependent anion-selective channel protein 3 WD repeat domain 20 WD repeat-containing protein 48 histone acetyltransferase peptidylprolyl isomerase ubiquitinyl hydrolase 1 ubiquitinyl hydrolase 1 ubiquitinyl hydrolase 1 ubiquitinyl hydrolase 1 ubiquitinyl hydrolase 1	A0A0A0MP93 A0A3Q1LF69 A0A3Q1LJ39 A0A3Q1LJN3 A0A3Q1LK42 A0A3Q1LT51 A0A3Q1LYE6 A0A3Q1M230 A0A3Q1MAA7 A0A3Q1MAX7 A0A3Q1MBN5 A0A3Q1MC38 A0A3Q1MDK7 A0A3Q1MDV7 A0A3Q1MF62 A0A3Q1MGB0 A0A3Q1MME1 A0A3Q1MMX0 A0A3Q1N3E8 A0A3Q1N5C0 A0A3Q1NK97 A0A452DHT6 A0JND0 A1L5A6 A2VDU3 A4IFU5 A5D9H7 A5PJW1 A5PKF9 A6H783 A6H7A0 A6H7B1 A6QLP0 A6QNM7 A6QR55 A7MB09 A7MBA2 A7MBD1 A7MBG4 A7MBG8 A7Z056 B0JYL0 E1B8G9 E1B8R5 E1B8T7 E1B9D9 E1BE92 E1BF92 E1BGD5 E1BGQ5 E1BGQ9 E1BH22 E1BHL3 E1BJZ0 E1BKJ5 E1BL26 E1BLZ0 E1BMF7 E1BND0 E1BP59 F1MBI1 F1MBM6 F1MCR4 F1MDX9 F1MKU1 F1MLV1 F1MRW5 F1MSB6 F1MUD4 F1MUU9 F1MUZ3 F1MV75 F1MVR8 F1MWE0 F1MXE4 F1MYE6 F1MYH8 F1N112 F1N2B6 F1N3P2 F1N4I2 F1N556 F1N5V1 F2Z4F9 F2Z4J1 G3MWV4 G3MYB1 G3N0M9 G3X7P3 G3X811 G3X822 G5E589 G5E5Q9 G5E630 G5E6I9 G5E6P9 G8JKW1 M5FK80 O46680 P0C0S9 P0C8Z3 P0CG53 P0CH28 P17870 P33672 P45879 P56701 P62194 P62808 P62992 P63048 P67939 P68002 Q08DU3 Q08E34 Q0IIF7 Q0IIM6 Q0V8S0 Q0VBY8 Q17QP9 Q1JQA2 Q1RMU2 Q24K02 Q27958 Q28044 Q29RI9 Q2HJ27 Q2HJE4 Q2HJF8 Q2KI42 Q2KII5 Q2KJ25 Q2KJ46 Q2YDE4 Q32KL2 Q32S29 Q3MHN0 Q3SYW8 Q3SZK6 Q3T030 Q3T0X5 Q3T0Y1 Q3T0Y5 Q3T108 Q3T139 Q3ZBD0 Q3ZBG0 Q3ZBL5 Q3ZCC3 Q3ZCK9 Q4A1L4 Q58DU5 Q5E964 Q5E987 Q5E9F9 Q5E9K0 Q5EAE2 Q8WNW7 Q95KU9	ADA3 ADRB2 ADRM1 AR ARHT1 ARRB1 ARRB2 ATXN7 AXIN1 AXIN2 BECN1 BIRC2 BIRC3 BIT1 CCNA1 CCNA2 CCP110 CDC20 CDC25A CLSPN CYLD CYLD1 DDB2 FKBP8 FOXO4 GATA3 H2AC10 H2AC12 H2AC18 H2AC21 H2AC25 H2AC6 H2AW H2B H2BC26 H2BC5 HGS HIF1A HIST1H2BI HIST3H2A IDE IFIH1 IKBKG IL33 KAT2A KEAP1 LOC112446467 LOC614881 LOC790134 MAP3K7 MAT2B MDM2 MUL1 MYC NEMO NFKBIA OTUB1 POLB PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMB1 PSMB2 PSMB3 PSMB4 PSMB5 PSMB6 PSMB7 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD6 PSMD7 PSMD8 PTEN PTRH2 RCE1 RHOT1 RIGI RIPK1 RNF123 RNF128 RNF146B RPS27A RUVBL1 SIAH2 SKP2 SMAD1 SMAD2 SMAD3 SMAD4 SMAD7 SMURF2 STAM2 SUG1 TAB1 TADA2B TADA3 TADA3L TAF10 TAF9B TGFBR1 TNKS TNKS2 TOMM20 TOMM70 TOMM70A TP53 TRAF2 TRAF6 TRAP2 TRRAP Tom70 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 UFD1 USP11 USP12 USP13 USP14 USP15 USP19 USP20 USP21 USP22 USP24 USP25 USP26 USP28 USP3 USP30 USP33 USP34 USP37 USP4 USP42 USP44 USP47 USP48 USP49 USP5 USP7 USP8 USP9X VDAC1 VDAC2 VDAC3 VDAC5P WDR20 WDR48 bIkBa
Regulation of IGF Activity by IGFBP	APOL3 protein APOL3 protein APOL3 protein Albumin Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase A Alpha-1-antiproteinase Alpha-2-HS-glycoprotein Alpha-L-fucosidase Alpha-fetoprotein Ameloblastin Amelogenin, X isoform Amelotin Amyloid-beta A4 protein Anoctamin Apolipoprotein A-I Apolipoprotein A-II Apolipoprotein A-V Apolipoprotein B Apolipoprotein E Apolipoprotein L3-like Apolipoprotein L3-like Apolipoprotein L3-like Apolipoprotein L3-like Apolipoprotein L3-like Apolipoprotein L3 BPI fold containing family B member 2 Bone morphogenetic protein 15 Bone morphogenetic protein 4 C4a anaphylatoxin CCN family member 1 Cadherin-2 Calumenin Chordin like 1 Coagulation factor V Complement C3 Cystatin-C Cytoskeleton associated protein 4 Dentin matrix acidic phosphoprotein 1 Disintegrin and metalloproteinase domain-containing protein 10 DnaJ homolog subfamily C member 3 Enamelin Endoplasmin FAM20A golgi associated secretory pathway pseudokinase FAM20C golgi associated secretory pathway kinase Fibrillin-1 Fibrinogen alpha chain Fibroblast growth factor 23 Fibronectin Follistatin-related protein 1 Galectin-1 Glucosidase 2 subunit beta Glypican-3 Golgi membrane protein 1 Growth arrest specific 6 Histidine rich calcium binding protein ITIH2 protein Insulin like growth factor binding protein 7 Insulin-like growth factor I Insulin-like growth factor II Insulin-like growth factor-binding protein 1 Insulin-like growth factor-binding protein 2 Insulin-like growth factor-binding protein 3 Insulin-like growth factor-binding protein 4 Insulin-like growth factor-binding protein 5 Interleukin-6 Kinectin 1 Kininogen 1 LOC510193 protein Latent transforming growth factor beta binding protein 1 MBTPS1 protein MIA SH3 domain ER export factor 3 Macrophage colony-stimulating factor 1 Matrilin 3 Matrix extracellular phosphoglycoprotein Matrix remodeling-associated protein 8 Melanotransferrin Menin Milk fat globule EGF and factor V/VIII domain containing Multiple EGF like domains 6 NTR domain-containing protein Nucleobindin-1 Pappalysin 2 Patatin like phospholipase domain containing 2 Proenkephalin-A Protein disulfide-isomerase A6 Protein disulfide-isomerase Protein shisa-5 Reticulocalbin 1 SERPINA10 protein SPARC like 1 Secreted phosphoprotein 1 Secreted phosphoprotein 24 Secretogranin-1 Secretogranin-2 Secretogranin-3 Serine protease 23 Serotransferrin Serpin family D member 1 Stanniocalcin-2 Syndecan-2 Tenascin C Trans-golgi network protein 2 Transmembrane protein 132A Uncharacterized protein Uncharacterized protein VGF nerve growth factor inducible Versican core protein Vitamin K-dependent protein C Wolframin ER transmembrane glycoprotein ferroxidase von Willebrand factor A domain-containing protein 1	A0A140T881 A0A140T885 A0A140T897 A0A140T8C8 A0A140T8D3 A0A3Q1LIS3 A0A3Q1LMK4 A0A3Q1LRR3 A0A3Q1LUG2 A0A3Q1LVS2 A0A3Q1LZU0 A0A3Q1M2R2 A0A3Q1M616 A0A3Q1MB94 A0A3Q1MEX5 A0A3Q1MJT5 A0A3Q1N3Y2 A0A3Q1N5X6 A0A3Q1NAS1 A0A3Q1NC75 A0A3Q1NIX0 A0A452DHZ5 A0A452DII7 A0A452DJ03 A0A5H1ZRH6 A4FUZ9 A5D7R6 A5PJ69 A6QLI2 A6QP86 A6QPR4 A6QQR3 E1B8P3 E1BF00 E1BF93 E1BG25 E1BG36 E1BH06 E1BHJ7 E1BJF8 E1BJU2 E1BLA8 E1BNR0 F1MAZ4 F1MD94 F1ME65 F1MEA1 F1MI67 F1MJM1 F1MJW4 F1MKR5 F1MPP2 F1MRZ6 F1MVK1 F1MXX6 F1MY12 F1MZ40 F1N036 F1N076 F1N0I3 F1N444 F1N5H2 F2Z4E0 F6Q9Q9 F6QH94 F6QND5 F6QSG5 F6R4P6 F6RJ01 G3N2L2 G3N2W6 G3N348 G3X6N3 G3X724 G5E5A9 G5E5T0 O77836 P01035 P01211 P02817 P07455 P07456 P11116 P12763 P13384 P15497 P20616 P20959 P24591 P26892 P34955 P81282 P81644 P98133 Q05716 Q05717 Q08E55 Q0P5I0 Q10741 Q1LZE9 Q27967 Q28034 Q2KJH1 Q2UVX4 Q3SZ57 Q3T0A9 Q3ZBZ6 Q58D84 Q58DD4 Q6PX77 Q95M18	ADAM10 AFP AHSG ALB AMBN AMELX AMTN ANO8 APOA1 APOA2 APOA5 APOB APOE APOL3 APP BMP15 BMP4 BPIFB2 C3 C4A CALU CCN1 CDH2 CHGB CHGC CHRDL1 CKAP4 CP CSF1 CSPG2 CST3 DMP1 DNAJC3 ENAM F5 FAM20A FAM20C FBN1 FETUA FGA FGF23 FN1 FSTL1 FUCA2 GAS6 GOLM1 GPC3 GRP94 HRC HSP90B1 HSPC4 IGF1 IGF2 IGFBP1 IGFBP2 IGFBP3 IGFBP4 IGFBP5 IGFBP7 IL6 ITIH2 KNG1 KTN1 LGALS1 LOC107131209 LOC112442231 LOC112446726 LOC505078 LOC510193 LOC512905 LOC515697 LOC518495 LOC521214 LOC524576 LOC531557 LOC786352 LOC788334 LTBP1 MADM MATN3 MBTPS1 MEGF6 MELTF MEN1 MEPE MFGE8 MGAT4A MIA3 MXRA8 NUCB1 P4HB PAPPA2 PDIA6 PENK PI PNPLA2 PRKCSH PROC PRSS23 RCN1 SCG2 SCG3 SCOTIN SDC2 SERPINA1 SERPINA10 SERPIND1 SHISA5 SPARCL1 SPP1 SPP2 SPP24 STC2 TF TMEM132A TNC TRA1 VCAN VGF VWA1 WFS1
Post-translational protein phosphorylation	APOL3 protein APOL3 protein APOL3 protein Albumin Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase A Alpha-1-antiproteinase Alpha-2-HS-glycoprotein Alpha-L-fucosidase Alpha-fetoprotein Ameloblastin Amelogenin, X isoform Amelotin Amyloid-beta A4 protein Anoctamin Apolipoprotein A-I Apolipoprotein A-II Apolipoprotein A-V Apolipoprotein B Apolipoprotein E Apolipoprotein L3-like Apolipoprotein L3-like Apolipoprotein L3-like Apolipoprotein L3-like Apolipoprotein L3-like Apolipoprotein L3 BPI fold containing family B member 2 Bone morphogenetic protein 15 Bone morphogenetic protein 4 C4a anaphylatoxin CCN family member 1 Cadherin-2 Calumenin Chordin like 1 Coagulation factor V Complement C3 Cystatin-C Cytoskeleton associated protein 4 Dentin matrix acidic phosphoprotein 1 Disintegrin and metalloproteinase domain-containing protein 10 DnaJ homolog subfamily C member 3 Enamelin Endoplasmin FAM20A golgi associated secretory pathway pseudokinase FAM20C golgi associated secretory pathway kinase Fibrillin-1 Fibrinogen alpha chain Fibroblast growth factor 23 Fibronectin Follistatin-related protein 1 Galectin-1 Glucosidase 2 subunit beta Glypican-3 Golgi membrane protein 1 Growth arrest specific 6 Histidine rich calcium binding protein ITIH2 protein Insulin like growth factor binding protein 7 Insulin-like growth factor-binding protein 1 Insulin-like growth factor-binding protein 3 Insulin-like growth factor-binding protein 4 Insulin-like growth factor-binding protein 5 Interleukin-6 Kinectin 1 Kininogen 1 LOC510193 protein Latent transforming growth factor beta binding protein 1 MBTPS1 protein MIA SH3 domain ER export factor 3 Macrophage colony-stimulating factor 1 Matrilin 3 Matrix extracellular phosphoglycoprotein Matrix remodeling-associated protein 8 Melanotransferrin Menin Milk fat globule EGF and factor V/VIII domain containing Multiple EGF like domains 6 NTR domain-containing protein Nucleobindin-1 Patatin like phospholipase domain containing 2 Proenkephalin-A Protein disulfide-isomerase A6 Protein disulfide-isomerase Protein shisa-5 Reticulocalbin 1 SERPINA10 protein SPARC like 1 Secreted phosphoprotein 1 Secreted phosphoprotein 24 Secretogranin-1 Secretogranin-2 Secretogranin-3 Serine protease 23 Serotransferrin Serpin family D member 1 Stanniocalcin-2 Syndecan-2 Tenascin C Trans-golgi network protein 2 Transmembrane protein 132A Uncharacterized protein Uncharacterized protein VGF nerve growth factor inducible Versican core protein Vitamin K-dependent protein C Wolframin ER transmembrane glycoprotein ferroxidase von Willebrand factor A domain-containing protein 1	A0A140T881 A0A140T885 A0A140T897 A0A140T8C8 A0A140T8D3 A0A3Q1LIS3 A0A3Q1LMK4 A0A3Q1LRR3 A0A3Q1LUG2 A0A3Q1LVS2 A0A3Q1LZU0 A0A3Q1M2R2 A0A3Q1M616 A0A3Q1MB94 A0A3Q1MEX5 A0A3Q1MJT5 A0A3Q1N3Y2 A0A3Q1N5X6 A0A3Q1NAS1 A0A3Q1NC75 A0A3Q1NIX0 A0A452DHZ5 A0A452DII7 A0A452DJ03 A0A5H1ZRH6 A4FUZ9 A5D7R6 A5PJ69 A6QLI2 A6QP86 A6QPR4 A6QQR3 E1B8P3 E1BF93 E1BG25 E1BG36 E1BH06 E1BHJ7 E1BJF8 E1BJU2 E1BLA8 E1BNR0 F1MAZ4 F1MD94 F1ME65 F1MEA1 F1MI67 F1MJM1 F1MJW4 F1MKR5 F1MPP2 F1MRZ6 F1MVK1 F1MXX6 F1MY12 F1MZ40 F1N036 F1N076 F1N0I3 F1N444 F1N5H2 F2Z4E0 F6Q9Q9 F6QH94 F6QND5 F6QSG5 F6R4P6 F6RJ01 G3N2L2 G3N2W6 G3N348 G3X6N3 G3X724 G5E5A9 G5E5T0 O77836 P01035 P01211 P02817 P11116 P12763 P15497 P20616 P20959 P24591 P26892 P34955 P81282 P81644 P98133 Q05716 Q05717 Q08E55 Q0P5I0 Q10741 Q1LZE9 Q27967 Q28034 Q2KJH1 Q2UVX4 Q3SZ57 Q3T0A9 Q3ZBZ6 Q58D84 Q58DD4 Q6PX77 Q95M18	ADAM10 AFP AHSG ALB AMBN AMELX AMTN ANO8 APOA1 APOA2 APOA5 APOB APOE APOL3 APP BMP15 BMP4 BPIFB2 C3 C4A CALU CCN1 CDH2 CHGB CHGC CHRDL1 CKAP4 CP CSF1 CSPG2 CST3 DMP1 DNAJC3 ENAM F5 FAM20A FAM20C FBN1 FETUA FGA FGF23 FN1 FSTL1 FUCA2 GAS6 GOLM1 GPC3 GRP94 HRC HSP90B1 HSPC4 IGFBP1 IGFBP3 IGFBP4 IGFBP5 IGFBP7 IL6 ITIH2 KNG1 KTN1 LGALS1 LOC107131209 LOC112442231 LOC112446726 LOC505078 LOC510193 LOC512905 LOC515697 LOC518495 LOC521214 LOC524576 LOC531557 LOC786352 LOC788334 LTBP1 MADM MATN3 MBTPS1 MEGF6 MELTF MEN1 MEPE MFGE8 MGAT4A MIA3 MXRA8 NUCB1 P4HB PDIA6 PENK PI PNPLA2 PRKCSH PROC PRSS23 RCN1 SCG2 SCG3 SCOTIN SDC2 SERPINA1 SERPINA10 SERPIND1 SHISA5 SPARCL1 SPP1 SPP2 SPP24 STC2 TF TMEM132A TNC TRA1 VCAN VGF VWA1 WFS1
Regulation of CDH11 function	ADAM metallopeptidase domain 19 ADAM metallopeptidase domain 33 Angiomotin Angiopoietin-related protein 4 Cadherin 11 Catenin beta-1 Catenin delta 1 Junction plakoglobin	A0A3Q1M4X1 A0A3Q1MUL4 A2VDQ6 E1BQ11 F1ME22 Q0VCX4 Q2KJ51 Q8SPJ1	ADAM19 ADAM33 AMOT ANGPTL4 CDH11 CTNNB1 CTNND1 JUP
Interaction With Cumulus Cells And The Zona Pellucida	Beta-1,4-galactosyltransferase 1 Disintegrin and metalloproteinase domain-containing protein 2 Hyaluronidase Oviduct-specific glycoprotein Zona pellucida sperm-binding protein 2 Zona pellucida sperm-binding protein 3 Zona pellucida sperm-binding protein 4	A0A3Q1MHW1 A0A3S5ZPD7 A6H6X7 F1MZM9 G1K1H0 P08037 Q9BH11	ADAM2 B4GALT1 GALT GGTB2 LOC509761 OVGP1 ZP2 ZP3 ZP4 ZPB
LGI-ADAM interactions	ADAM metallopeptidase domain 22 ADAM metallopeptidase domain 23 Discs large MAGUK scaffold protein 4 LGI4 protein Leucine rich repeat LGI family member 2 Leucine rich repeat LGI family member 3 Leucine-rich glioma-inactivated protein 1 Syntaxin-1A Syntaxin-1B Voltage-dependent calcium channel gamma-2 subunit Voltage-dependent calcium channel gamma-3 subunit Voltage-dependent calcium channel gamma-4 subunit Voltage-dependent calcium channel gamma-8 subunit	A0A3Q1LKG2 A0A3Q1MVZ5 A0A3Q1NF99 A0JNG9 A6QLD0 E1BFY8 F1MM66 F1MV40 F1MZT1 P32850 P61267 Q0VD05 Q5E9T6	ADAM22 ADAM23 CACNG2 CACNG3 CACNG4 CACNG8 DLG4 LGI1 LGI2 LGI3 LGI4 STX1A STX1B STX1B2
O-glycosylation of TSR domain-containing proteins	A disintegrin and metalloproteinase with thrombospondin motifs 2 A disintegrin and metalloproteinase with thrombospondin motifs 4 ADAM metallopeptidase with thrombospondin type 1 motif 10 ADAM metallopeptidase with thrombospondin type 1 motif 12 ADAM metallopeptidase with thrombospondin type 1 motif 13 ADAM metallopeptidase with thrombospondin type 1 motif 14 ADAM metallopeptidase with thrombospondin type 1 motif 15 ADAM metallopeptidase with thrombospondin type 1 motif 16 ADAM metallopeptidase with thrombospondin type 1 motif 17 ADAM metallopeptidase with thrombospondin type 1 motif 18 ADAM metallopeptidase with thrombospondin type 1 motif 19 ADAM metallopeptidase with thrombospondin type 1 motif 1 ADAM metallopeptidase with thrombospondin type 1 motif 20 ADAM metallopeptidase with thrombospondin type 1 motif 3 ADAM metallopeptidase with thrombospondin type 1 motif 5 ADAM metallopeptidase with thrombospondin type 1 motif 6 ADAM metallopeptidase with thrombospondin type 1 motif 8 ADAM metallopeptidase with thrombospondin type 1 motif 9 ADAMTS like 1 ADAMTS like 3 ADAMTS like 4 ADAMTS like 5 Beta 3-glucosyltransferase Complement factor properdin GDP-fucose protein O-fucosyltransferase 2 SCO-spondin Semaphorin 5A Semaphorin 5B Somatomedin-B and thrombospondin type-1 domain-containing protein Spondin-1 THSD1 protein Thrombospondin 1 Thrombospondin 2 Thrombospondin type 1 domain containing 7A Thrombospondin type 1 domain containing 7B	A0A3Q1M2R9 A0A3Q1MG57 A0A3Q1MQV3 A5D7K2 A7MB07 E1B8S3 E1B900 E1BC50 E1BCW5 E1BFV4 E1BI72 E1BK03 E1BK41 E1BMV7 E1BN99 F1MF39 F1MKA0 F1ML13 F1MLA7 F1MLQ7 F1MP11 F1MRZ2 F1MTB6 F1MVP0 F1MXQ0 F1MXR3 F1MXU9 F1N1W3 F1N303 F1N7N4 G3MXP8 G8JKX1 P79331 Q32L50 Q9GLX9	ADAMTS1 ADAMTS10 ADAMTS12 ADAMTS13 ADAMTS14 ADAMTS15 ADAMTS16 ADAMTS17 ADAMTS18 ADAMTS19 ADAMTS2 ADAMTS20 ADAMTS3 ADAMTS4 ADAMTS5 ADAMTS6 ADAMTS8 ADAMTS9 ADAMTSL1 ADAMTSL3 ADAMTSL4 ADAMTSL5 B3GLCT CFP NPI POFUT2 RPESP SBSPON SEMA5A SEMA5B SPON1 SSPO THBS1 THBS2 THSD1 THSD7A THSD7B VSGP
Platelet Adhesion to exposed collagen	ADAM metallopeptidase with thrombospondin type 1 motif 13 Glycoprotein IX platelet Glycoprotein Ib platelet subunit beta Glycoprotein V platelet High affinity immunoglobulin epsilon receptor subunit gamma Tyrosine-protein kinase Fyn Tyrosine-protein kinase von Willebrand factor	A0JNB0 E1B863 E1BG29 F1MVP0 F1N0R5 F1N1G4 F1N261 Q9BDR7	ADAMTS13 FCER1G FYN GP1BB GP5 GP9 LYN VWF
Collagen biosynthesis and modifying enzymes	A disintegrin and metalloproteinase with thrombospondin motifs 2 ADAM metallopeptidase with thrombospondin type 1 motif 14 ADAM metallopeptidase with thrombospondin type 1 motif 3 COL8A1 protein Collagen alpha-1(I) chain Collagen alpha-1(II) chain Collagen alpha-1(IV) chain Collagen alpha-2(I) chain Collagen beta(1-O)galactosyltransferase 2 Collagen type III alpha 1 chain Collagen type IV alpha 3 chain Collagen type IV alpha 5 chain Collagen type IV alpha 6 chain Collagen type V alpha 1 chain Collagen type V alpha 3 chain Collagen type VI alpha 1 chain Collagen type VI alpha 2 chain Collagen type VI alpha 3 chain Collagen type VI alpha 5 chain Collagen type VI alpha 6 chain Collagen type VIII alpha 2 chain Collagen type X alpha 1 chain Collagen type XI alpha 1 chain Collagen type XI alpha 2 chain Collagen type XII alpha 1 chain Collagen type XIII alpha 1 chain Collagen type XIV alpha 1 chain Collagen type XVI alpha 1 chain Collagen type XVII alpha 1 chain Collagen type XVIII alpha 1 chain Collagen type XX alpha 1 chain Collagen type XXIII alpha 1 chain Collagen type XXVI alpha 1 chain Collagen type XXVII alpha 1 chain Collagen type XXVIII alpha 1 chain Metalloendopeptidase Metalloendopeptidase Metalloendopeptidase Procollagen C-endopeptidase enhancer 2 Procollagen C-endopeptidase enhancer Procollagen galactosyltransferase 1 Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1 Prolyl 4-hydroxylase subunit alpha-1 Prolyl 4-hydroxylase subunit alpha-3 Protein disulfide-isomerase Serpin H1 procollagen-lysine 5-dioxygenase procollagen-lysine 5-dioxygenase procollagen-proline 3-dioxygenase procollagen-proline 3-dioxygenase procollagen-proline 4-dioxygenase	A0A3Q1LXW3 A0A3Q1LYA4 A0A3Q1M646 A0A3Q1M970 A0A3Q1NK51 A5PK45 A6QLY3 A7E303 A7MB83 E1BA17 E1BB91 E1BBC6 E1BC50 E1BEV7 E1BFV4 E1BI98 E1BKJ9 F1MD40 F1MET0 F1MF35 F1MJQ6 F1MJR6 F1MKG2 F1MKP1 F1MRP6 F1MSJ7 F1MZ30 F1MZU6 F1N0K0 F1N0V8 F1N0X6 F1N401 F1N6W9 F6Q9Q9 F6RND5 G3MXK9 G3MZI7 G3N021 G3N2F2 G8JKV7 P02453 P02459 P02465 P79331 Q08E14 Q1RMU3 Q2HJB6 Q2KJH6 Q75UG4 Q7SIB2 W0SK50	ADAMTS14 ADAMTS2 ADAMTS3 BMP1 COL10A1 COL11A1 COL11A2 COL12A1 COL13A1 COL14A1 COL16A1 COL17A1 COL18A1 COL1A1 COL1A2 COL20A1 COL23A1 COL26A1 COL27A1 COL28A1 COL2A1 COL3A1 COL4A1 COL4A3 COL4A5 COL4A6 COL5A1 COL5A3 COL6A1 COL6A2 COL6A3 COL6A5 COL6A6 COL8A1 COL8A2 COLGALT1 COLGALT2 GLT25D1 LEPREL1 NPI P3H2 P3H3 P4HA1 P4HA2 P4HA3 P4HB PCOLCE PCOLCE2 PLOD1 PLOD2 PLOD3 SERPINH1 TLL1 TLL2
G alpha (z) signalling events	Adenylate cyclase type 1 Adenylate cyclase type 2 Adenylate cyclase type 3 Adenylate cyclase type 4 Adenylate cyclase type 5 Adenylate cyclase type 6 Adenylate cyclase type 8 Alpha-2A adrenergic receptor Alpha-2B adrenergic receptor Alpha-2C adrenergic receptor G protein subunit alpha z G protein subunit beta 3 G protein subunit gamma 13 GNB4 protein Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 Guanine nucleotide-binding protein G(T) subunit gamma-T1 Guanine nucleotide-binding protein subunit beta-5 Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma RGS17 protein Regulator of G-protein signaling 16 Regulator of G-protein signaling 20 adenylate cyclase	A0A3Q1LQ48 A0A3Q1MA58 A0A3Q1MM27 A0A3Q1NGS8 A0A3S5ZPL0 A4IFL6 A5PKD6 A7MBG6 E1B8Q3 E1B9K3 E1BHU9 E1BM79 E1BQ12 F1MJV4 F1MPC9 F1MYW8 G3X6S2 O46471 P02698 P11017 P19754 P30671 P50154 P62871 P63212 P63214 P63217 P79348 Q28024 Q28838 Q3SZ98 Q5E9F0	ADCY1 ADCY2 ADCY3 ADCY4 ADCY5 ADCY6 ADCY8 ADCY9 ADRA2A ADRA2B ADRA2C GNAZ GNB1 GNB2 GNB3 GNB4 GNB5 GNG10 GNG11 GNG12 GNG13 GNG2 GNG3 GNG4 GNG5 GNG7 GNG8 GNGT1 GNGT12 GNGT2 GNGT3 GNGT5 GNGT7 GNGT8 RGS16 RGS17 RGS20
PKA activation	Adenylate cyclase type 1 Adenylate cyclase type 2 Adenylate cyclase type 3 Adenylate cyclase type 4 Adenylate cyclase type 5 Adenylate cyclase type 6 Adenylate cyclase type 8 EF-hand domain-containing protein EF-hand domain-containing protein Protein kinase cAMP-dependent type I regulatory subunit beta adenylate cyclase cAMP-dependent protein kinase catalytic subunit alpha cAMP-dependent protein kinase type I-alpha regulatory subunit cAMP-dependent protein kinase type II-alpha regulatory subunit cAMP-dependent protein kinase	A0A3Q1MA58 A0A3Q1MCI6 A0A3Q1MR28 A0A452DJE2 E1B9K3 E1BHU9 E1BM79 E1BQ12 F1MJV4 F1MLH6 F1MPC9 P00514 P00515 P00517 P19754	ADCY1 ADCY2 ADCY3 ADCY4 ADCY5 ADCY6 ADCY8 ADCY9 CALM PRKACA PRKACB PRKAR1A PRKAR1B PRKAR2A
Hedgehog 'off' state	Adenylate cyclase type 1 Adenylate cyclase type 2 Adenylate cyclase type 3 Adenylate cyclase type 4 Adenylate cyclase type 5 Adenylate cyclase type 6 Adenylate cyclase type 8 Fuzzy planar cell polarity protein G protein-coupled receptor 161 GLI family zinc finger 1 GLI family zinc finger 2 GLI family zinc finger 3 Intraflagellar transport 140 Intraflagellar transport 52 homolog (Chlamydomonas) Intraflagellar transport 88 Intraflagellar transport protein 122 homolog Intraflagellar transport protein 57 homolog Kinesin family member 7 Kinesin-like protein OFD1 centriole and centriolar satellite protein Patched 1 Protein inturned Protein kinase cAMP-dependent type I regulatory subunit beta Protein smoothened RPGRIP1 like SUFU negative regulator of hedgehog signaling TTC21B protein Tubby-like protein WD repeat domain 19 WD repeat-containing protein 35 adenylate cyclase cAMP-dependent protein kinase catalytic subunit alpha cAMP-dependent protein kinase type I-alpha regulatory subunit cAMP-dependent protein kinase type II-alpha regulatory subunit cAMP-dependent protein kinase	A0A3Q1LM07 A0A3Q1LTC8 A0A3Q1LWP8 A0A3Q1MA58 A0A3Q1MCI6 A0A3Q1MDV1 A0A3Q1MNB3 A0A452DIR3 A0A452DJE2 A6H727 A7MB60 E1B7Q4 E1B860 E1B9K3 E1BBF8 E1BE57 E1BHU9 E1BJB4 E1BKE3 E1BM79 E1BQ12 F1MCY1 F1MDL2 F1MG59 F1MJV4 F1MPC9 F1N215 F1N7S0 G3N1D5 P00514 P00515 P00517 P19754 Q2YDN1 Q32KR5	ADCY1 ADCY2 ADCY3 ADCY4 ADCY5 ADCY6 ADCY8 ADCY9 FUZ GLI1 GLI2 GLI3 GPR161 IFT122 IFT140 IFT52 IFT57 IFT88 INTU KIF3A KIF7 OFD1 PDZD6 PRKACA PRKACB PRKAR1A PRKAR1B PRKAR2A PTCH1 RPGRIP1L SMO SUFU TTC21B TULP3 WDR19 WDR35
Adenylate cyclase inhibitory pathway	Adenylate cyclase type 1 Adenylate cyclase type 2 Adenylate cyclase type 3 Adenylate cyclase type 4 Adenylate cyclase type 5 Adenylate cyclase type 6 Adenylate cyclase type 8 G protein subunit alpha L Guanine nucleotide-binding protein G(i) subunit alpha-1 Guanine nucleotide-binding protein G(i) subunit alpha-2 Guanine nucleotide-binding protein G(i) subunit alpha-3 Guanine nucleotide-binding protein G(t) subunit alpha-3 adenylate cyclase	A0A3Q1M3D6 A0A3Q1MA58 A7MBH9 E1B9K3 E1BHU9 E1BM79 E1BQ12 F1MJV4 F1MPC9 P0C7Q4 P19754 P63097 Q3ZCA7	ADCY1 ADCY2 ADCY3 ADCY4 ADCY5 ADCY6 ADCY8 ADCY9 GNAI1 GNAI2 GNAI3 GNAL GNAT3
Adenylate cyclase activating pathway	Adenylate cyclase type 1 Adenylate cyclase type 2 Adenylate cyclase type 3 Adenylate cyclase type 4 Adenylate cyclase type 5 Adenylate cyclase type 6 Adenylate cyclase type 8 G protein subunit alpha L adenylate cyclase	A0A3Q1M3D6 A0A3Q1MA58 E1B9K3 E1BHU9 E1BM79 E1BQ12 F1MJV4 F1MPC9 P19754	ADCY1 ADCY2 ADCY3 ADCY4 ADCY5 ADCY6 ADCY8 ADCY9 GNAL
Adrenaline,noradrenaline inhibits insulin secretion	Adenylate cyclase type 5 Adenylate cyclase type 6 Alpha-2A adrenergic receptor Alpha-2C adrenergic receptor G protein subunit beta 3 G protein subunit gamma 13 GNB4 protein Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 Guanine nucleotide-binding protein G(T) subunit gamma-T1 Guanine nucleotide-binding protein G(i) subunit alpha-1 Guanine nucleotide-binding protein G(i) subunit alpha-2 Guanine nucleotide-binding protein subunit beta-5 Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma	A0A3Q1LQ48 A0A3Q1NGS8 A0A3S5ZPL0 A4IFL6 A5PKD6 A7MBH9 E1B8Q3 E1B9K3 E1BHU9 F1MYW8 P02698 P11017 P30671 P50154 P62871 P63097 P63212 P63214 P63217 Q28024 Q28838 Q3SZ98 Q5E9F0	ADCY5 ADCY6 ADRA2A ADRA2C GNAI1 GNAI2 GNB1 GNB2 GNB3 GNB4 GNB5 GNG10 GNG11 GNG12 GNG13 GNG2 GNG3 GNG4 GNG5 GNG7 GNG8 GNGT1 GNGT12 GNGT2 GNGT3 GNGT5 GNGT7 GNGT8
G alpha (s) signalling events	5-hydroxytryptamine receptor 4 5-hydroxytryptamine receptor 6 5-hydroxytryptamine receptor 7 Adenosine receptor A2 Adenosine receptor A2b Adrenocorticotropic hormone receptor Arginine vasopressin Beta-1 adrenergic receptor Beta-2 adrenergic receptor Beta-3 adrenergic receptor Beta-adrenergic receptor kinase 1 Beta-arrestin-1 Beta-arrestin-2 Calcitonin gene-related peptide type 1 receptor Calcitonin receptor Calcitonin-related polypeptide 3 Calcitonin Corticoliberin Corticotropin releasing hormone receptor 2 D(1A) dopamine receptor D(1B) dopamine receptor Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A Follicle-stimulating hormone receptor Follitropin subunit beta G protein subunit beta 3 G protein subunit gamma 13 G protein-coupled receptor 15 G protein-coupled receptor 176 G protein-coupled receptor 20 G protein-coupled receptor 25 G protein-coupled receptor 39 G protein-coupled receptor 83 G protein-coupled receptor kinase 3 G protein-coupled receptor kinase 5 G protein-coupled receptor kinase G-protein coupled bile acid receptor 1 G-protein coupled receptor 84 G-protein coupled receptors family 1 profile domain-containing protein G-protein coupled receptors family 1 profile domain-containing protein G-protein coupled receptors family 1 profile domain-containing protein GNB4 protein Gastric inhibitory polypeptide receptor Gastric inhibitory polypeptide Glucagon like peptide 2 receptor Glucagon receptor Glycoprotein hormone subunit alpha 2 Glycoprotein hormone subunit beta 5 Glycoprotein hormones alpha chain Growth hormone releasing hormone receptor Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 Guanine nucleotide-binding protein G(T) subunit gamma-T1 Guanine nucleotide-binding protein subunit beta-5 Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Histamine H2 receptor Insulin-like 3 Islet amyloid polypeptide Lutropin subunit beta Lutropin-choriogonadotropic hormone receptor Melanocortin receptor 4 Melanocortin receptor 5 Melanocortin-3-receptor Melanocyte-stimulating hormone receptor Neuropeptide S receptor 1 Neuropeptide S Parathyroid hormone 2 receptor Parathyroid hormone-related protein Parathyroid hormone/parathyroid hormone-related peptide receptor Parathyroid hormone Phosphodiesterase Phosphodiesterase Phosphodiesterase Phosphodiesterase Phosphodiesterase Phosphodiesterase Phosphodiesterase Phosphodiesterase Phosphodiesterase Phosphodiesterase Phosphodiesterase Phosphodiesterase Pituitary adenylate cyclase-activating polypeptide type I receptor Pituitary adenylate cyclase-activating polypeptide Pro-adrenomedullin Pro-glucagon Pro-opiomelanocortin Prostaglandin D2 receptor Prostaglandin E receptor 2 Prostaglandin E2 receptor EP4 subtype Prostaglandin I2 receptor Purinergic receptor P2Y11 RAMP2 protein Receptor activity-modifying protein 1 Relaxin family peptide receptor 1 Relaxin family peptide receptor 2 Secretin receptor Secretin Somatoliberin Thyrotropin receptor Thyrotropin subunit beta Trace amine associated receptor 2 Trace amine associated receptor 5 Trace amine associated receptor 9 Trace amine-associated receptor 1 Tuberoinfundibular peptide of 39 residues VIP peptides Vasoactive intestinal peptide receptor 1 Vasoactive intestinal peptide receptor 2 Vasopressin V2 receptor	A0A0F7RPV8 A0A140T893 A0A3Q1LXY0 A0A3Q1M1E8 A0A3Q1M3R2 A0A3Q1M5G0 A0A3Q1M5L1 A0A3Q1MB83 A0A3Q1MCI3 A0A3Q1ML96 A0A3Q1MLD1 A0A3Q1MQC7 A0A3Q1MQZ8 A0A3Q1MSN3 A0A3Q1MW13 A0A3Q1MZ56 A0A3Q1N5S8 A0A3Q1N6Q5 A0A3Q1NGS8 A0A3S5ZPL0 A0A452DI56 A0A452DIH0 A4FV02 A4IFL6 A5PKD6 A6H7J8 B5UBG1 E1B7Q8 E1B8G5 E1B8Q3 E1B8V8 E1B9U9 E1BAY1 E1BC51 E1BCM8 E1BD70 E1BD86 E1BE22 E1BK27 E1BKB6 E1BKC2 E1BKU0 E1BN64 E1BP29 E1BPD8 E1BQ27 F1MBI5 F1MF07 F1MI30 F1MIT6 F1MJF8 F1MJZ0 F1MLY6 F1MQC0 F1MT42 F1MTC9 F1MU50 F1MX10 F1MX56 F1MYW8 F1MZJ8 F1N0G5 F1N2L8 F1N4F6 F1N5T6 F1N625 F6Q8B6 F6R653 F6R930 G3MWJ9 G3MZW8 G3X6P6 G3X811 G3X880 G3X8D2 O62827 O77801 P01190 P01217 P01223 P01268 P01272 P02698 P04651 P04837 P11017 P14100 P17870 P21146 P26818 P30671 P34974 P43249 P47798 P48044 P50154 P56451 P58073 P62871 P63212 P63214 P63217 P63292 P81401 Q0VBW3 Q0VCW5 Q1LZD0 Q28024 Q28044 Q29627 Q2KI97 Q3SZ98 Q5E9F0 Q862A9 Q95136 Q95MI6 Q9GLJ8 Q9TUJ0	ADCYAP1 ADCYAP1R1 ADM ADORA2A ADORA2B ADRB1 ADRB2 ADRB3 ADRBK1 ADRBK2 ARRB1 ARRB2 AVP AVPR2 CALC3 CALCA CALCR CALCRL CGA CRH CRHR2 CT D1AR DRD1 DRD5 FSHB FSHR GCG GCGR GHRH GHRHR GIP GIPR GLP2R GNB1 GNB2 GNB3 GNB4 GNB5 GNG10 GNG11 GNG12 GNG13 GNG2 GNG3 GNG4 GNG5 GNG7 GNG8 GNGT1 GNGT12 GNGT2 GNGT3 GNGT5 GNGT7 GNGT8 GPA2 GPB5 GPBAR1 GPHA2 GPHB5 GPR15 GPR176 GPR20 GPR25 GPR39 GPR83 GPR84 GPRK5 GRK2 GRK3 GRK5 GRK6 HRH2 HTR4 HTR6 HTR7 IAPP INSL3 LHB LHCGR LOC511136 LOC514876 LOC516101 MC1R MC2R MC3R MC4R MC5R MSHR NPS NPSR1 P2RY11 PDE10A PDE11A PDE1A PDE1B PDE2A PDE3A PDE3B PDE4A PDE4C PDE4D PDE7B PDE8A PDE8B POMC PTGDR PTGER2 PTGER4 PTGIR PTH PTH1R PTH2 PTH2R PTHLH RAMP1 RAMP2 RLF RXFP1 RXFP2 SCT SCTR TAAR1 TAAR2 TAAR3 TAAR5 TAAR9 TGR5 TSHB TSHR VIP VIPR1 VIPR2
Glucagon-type ligand receptors	G protein subunit beta 3 G protein subunit gamma 13 GNB4 protein Gastric inhibitory polypeptide receptor Gastric inhibitory polypeptide Glucagon like peptide 2 receptor Glucagon receptor Growth hormone releasing hormone receptor Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 Guanine nucleotide-binding protein G(T) subunit gamma-T1 Guanine nucleotide-binding protein subunit beta-5 Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Pituitary adenylate cyclase-activating polypeptide type I receptor Pituitary adenylate cyclase-activating polypeptide Pro-glucagon Secretin receptor Secretin Somatoliberin VIP peptides Vasoactive intestinal peptide receptor 1 Vasoactive intestinal peptide receptor 2	A0A3Q1M5G0 A0A3Q1MB83 A0A3Q1NGS8 A0A3S5ZPL0 A4FV02 A4IFL6 A5PKD6 E1B8G5 E1B8Q3 E1BAY1 E1BKB6 F1MF07 F1MIT6 F1MQC0 F1MYW8 P01272 P02698 P11017 P30671 P50154 P62871 P63212 P63214 P63217 P63292 P81401 Q28024 Q29627 Q3SZ98 Q5E9F0 Q9TUJ0	ADCYAP1 ADCYAP1R1 GCG GCGR GHRH GHRHR GIP GIPR GLP2R GNB1 GNB2 GNB3 GNB4 GNB5 GNG10 GNG11 GNG12 GNG13 GNG2 GNG3 GNG4 GNG5 GNG7 GNG8 GNGT1 GNGT12 GNGT2 GNGT3 GNGT5 GNGT7 GNGT8 SCT SCTR VIP VIPR1 VIPR2
Miscellaneous transport and binding events	ANKH inorganic pyrophosphate transport regulator Adducin 1 Adducin 2 Adducin 3 Alpha-2-glycoprotein 1, zinc-binding Cystinosin Dematin LRRC8D protein Leucine rich repeat containing 8 VRAC subunit A Leucine rich repeat containing 8 VRAC subunit B Magnesium transporter NIPA2 Magnesium transporter protein 1 Magnesium transporter NIPA like domain containing 1 NIPA like domain containing 2 NIPA like domain containing 3 NIPA like domain containing 4 NIPA magnesium transporter 1 Prolactin-induced protein Prolactin-inducible protein homolog Solute carrier family 66 member 1 Tumor suppressor candidate 3 Volume-regulated anion channel subunit LRRC8C Volume-regulated anion channel subunit LRRC8E	A0A3Q1N598 A0A3Q1NDE1 A0A452DK44 A4IFE5 A5PK13 A6QR45 A7MB63 E1BD04 E1BDX2 E1BDX3 E1BHG8 E1BHK2 E1BLE7 F1MAW1 F1MCV8 F1MFE0 F1MII2 F1MXA4 F1N136 F6PRJ0 G3MY77 Q08DM1 Q08E42 Q3SWX0	ADD1 ADD2 ADD3 ANKH AZGP1 CTNS DMT DMTN EPB49 LLRC8A LOC104972276 LRRC8A LRRC8B LRRC8C LRRC8D LRRC8E MAGT1 MRS2 NIPA1 NIPA2 NIPAL1 NIPAL2 NIPAL3 NIPAL4 PIP SLC66A1 TUSC3
Caspase-mediated cleavage of cytoskeletal proteins	Adducin 1 Caspase 7 Caspase 8 Caspase-3 Caspase-6 GAS2 protein Gelsolin Plectin Sorbin and SH3 domain containing 2 Spectrin alpha, non-erythrocytic 1 Vimentin	A0A3Q1LNC8 A0A3Q1MRS3 A0A3Q1MUK3 A8E4Q5 E1BHK2 F1MB04 F1MD58 F1N1I6 G3X702 P48616 Q2LGB8	ADD1 CASP3 CASP6 CASP7 CASP8 GAS2 GSN PLEC SORBS2 SPTAN1 VIM

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