Endogenous sterols
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- ADX
- AHR
- ARNT
- ARNT2
- CYP11A1
- CYP11B1
- CYP19A1
- CYP1B1
- CYP21
- CYP21A1
- CYP21A2
- CYP27A1
- CYP39A1
- CYP46A1
- CYP4V2
- CYP51A1
- CYP7A1
- FDX1
- FDX1L
- FDX2
- FDXR
- LOC112449566
- NCOA1
- NCOA2
- NR1H4
- POMC
- RXRA
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TAK1-dependent IKK and NF-kappa-B activation
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- AGER
- APP
- CAAF1
- CHUK
- HMG1
- HMGB1
- IKBKB
- IKBKG
- IKKA
- NEMO
- NFKB1
- NFKB2
- NFKBIA
- NFKBIB
- NKIRAS1
- NKIRAS2
- RELA
- S100A12
- S100B
- bIkBa
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ECM proteoglycans
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- ACAN
- AGRN
- BCAN
- BGN
- COMP
- CRTL1
- CSPG2
- DCN
- DMP1
- DSPP
- HAPLN1
- ITGA2
- ITGA2B
- ITGA7
- ITGA9
- ITGAV
- ITGAX
- ITGB1
- ITGB3
- ITGB5
- ITGB6
- MATN1
- MATN3
- MATN4
- NCAN
- SERPINE1
- SPARC
- TNC
- TNN
- TNR
- TNXB
- VCAN
- VTN
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Keratan sulfate biosynthesis
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- Aggrecan core protein
- Beta-1,4-galactosyltransferase 1
- Beta-1,4-galactosyltransferase 2
- Beta-1,4-galactosyltransferase
- Beta-1,4-galactosyltransferase
- Beta-1,4-galactosyltransferase
- Beta-1,4-glucuronyltransferase 1
- CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1
- Fibromodulin
- Gal-NAc6S
- Hexosyltransferase
- Hexosyltransferase
- Keratocan
- Lumican
- Osteomodulin
- Proline and arginine rich end leucine rich repeat protein
- ST3 beta-galactoside alpha-2,3-sialyltransferase 3
- ST3 beta-galactoside alpha-2,3-sialyltransferase 4
- Solute carrier family 35 member D2
- Sulfotransferase
- Sulfotransferase
- Type 2 lactosamine alpha-2,3-sialyltransferase
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- ACAN
- B3GNT1
- B3GNT2
- B3GNT4
- B3GNT6
- B4GALT1
- B4GALT2
- B4GALT4
- B4GALT5
- B4GALT6
- B4GAT1
- CHST1
- CHST2
- FMOD
- GALT
- GGTB2
- KERA
- LDC
- LUM
- OMD
- PRELP
- SIAT10
- SLC35D2
- ST3GAL1
- ST3GAL2
- ST3GAL3
- ST3GAL4
- ST3GAL6
- siat4B
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Keratan sulfate degradation
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- ACAN
- FMOD
- GLB1
- GLB1L
- GLB1L2
- GNS
- HEXA
- HEXB
- KERA
- LDC
- LUM
- OMD
- PRELP
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HS-GAG degradation
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- AGRN
- GLB1
- GLB1L
- GLB1L2
- GPC1
- GPC2
- GPC3
- GPC4
- GPC5
- GUSB
- HPSE
- HPSE2
- IDS
- IDUA
- NAGLU
- SDC1
- SDC2
- SDC4
- SGSH
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A tetrasaccharide linker sequence is required for GAG synthesis
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- AGRN
- B3GALT6
- B3GAT1
- B3GAT3
- B4GALT7
- BCAN
- BGN
- CSPG2
- CSPG4
- CSPG5
- DCN
- GPC1
- GPC2
- GPC3
- GPC4
- GPC5
- NCAN
- SDC1
- SDC2
- SDC4
- VCAN
- XYLT1
- XYLT2
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HS-GAG biosynthesis
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- AGRN
- EXT1
- EXT2
- GPC1
- GPC2
- GPC3
- GPC4
- GPC5
- HS2ST1
- HS3ST1
- HS3ST2
- HS3ST3A1
- HS3ST3B1
- HS3ST5
- HS3ST6
- HS6ST2
- HS6ST3
- NDST1
- NDST2
- NDST4
- SDC1
- SDC2
- SDC4
- SLC35D2
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HDL remodeling
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- ALB
- APOA1
- APOC2
- APOC3
- APOE
- LCAT
- LIPG
- PLTP
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Cytoprotection by HMOX1
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- Albumin
- Biliverdin reductase A
- Cytochrome c oxidase subunit 1
- Cytochrome c oxidase subunit 2
- Cytochrome c oxidase subunit 3
- Cytochrome c oxidase subunit 4 isoform 1, mitochondrial
- Cytochrome c oxidase subunit 4
- Cytochrome c oxidase subunit 5A, mitochondrial
- Cytochrome c oxidase subunit 6A1, mitochondrial
- Cytochrome c oxidase subunit 6A2, mitochondrial
- Cytochrome c oxidase subunit 6B2
- Cytochrome c oxidase subunit 6C
- Cytochrome c oxidase subunit 7A-related protein, mitochondrial
- Cytochrome c oxidase subunit 7A1, mitochondrial
- Cytochrome c oxidase subunit 7A2, mitochondrial
- Cytochrome c oxidase subunit 7B, mitochondrial
- Cytochrome c oxidase subunit 7B, mitochondrial
- Cytochrome c oxidase subunit 7C, mitochondrial
- Cytochrome c oxidase subunit 8
- Cytochrome c oxidase subunit 8
- Cytochrome c oxidase subunit NDUFA4
- Cytochrome c oxidase subunit NDUFA4
- Cytochrome c
- DNA helicase
- Fatty acid-binding protein, liver
- Flavin reductase (NADPH)
- HIG1 hypoxia inducible domain family member 1C
- Heme oxygenase 1
- Hemoglobin subunit alpha
- Hemoglobin subunit beta
- Histone deacetylase 3
- Mediator of RNA polymerase II transcription subunit 1
- Multidrug resistance-associated protein 1
- Nuclear receptor coactivator 6
- Nuclear receptor coactivator
- Nuclear receptor coactivator
- Nuclear receptor corepressor 1
- Nuclear receptor corepressor 2
- Peroxisome proliferator-activated receptor alpha
- Retinoic acid receptor RXR
- SIN3 transcription regulator family member A
- SIN3 transcription regulator family member B
- SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
- Transducin beta like 1 X-linked
- Trimethylguanosine synthase
- Uncharacterized protein
- heme oxygenase (biliverdin-producing)
- histone acetyltransferase
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- ABCC1
- ALB
- BLVRA
- BLVRB
- CHD9
- COII
- COX1
- COX2
- COX3
- COX4
- COX4I1
- COX4I2
- COX5A
- COX6A
- COX6A1
- COX6A2
- COX6B2
- COX6C
- COX7A1
- COX7A2
- COX7A2L
- COX7B
- COX7C
- COX7CP1
- COXII
- CREBBP
- CYC
- CYCS
- FABP1
- HBA
- HBB
- HDAC3
- HIGD1C
- HMOX1
- HMOX2
- LOC100296227
- LOC100300759
- LOC783202
- MED1
- MRP1
- MT-CO2
- MTCO2
- NCOA1
- NCOA2
- NCOA6
- NCOR1
- NCOR2
- NDUFA4
- PPARA
- RXRA
- SCAN
- SIN3A
- SIN3B
- SMARCD3
- TBL1X
- TGS1
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Ciprofloxacin ADME
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- ABCG2
- ALB
- OCT1
- SLC22A1
- SLCO1A2
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Scavenging of heme from plasma
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- ALB
- CD163
- HBA
- HBB
- HPX
- LRP1
- M130
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Sphingolipid catabolism
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- ACER1
- ACER2
- ACER3
- ALDH3A2
- ALDH3B1
- PLPP1
- PLPP2
- PLPP3
- PPAP2B
- PPAP2C
- SGPL1
- SGPP1
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RND1 GTPase cycle
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- ALDH3A2
- ANKRD26
- ARHGAP35
- ARHGAP5
- CAV1
- CCDC88A
- CPD
- DEPDC1B
- DLG5
- DSP
- DST
- EPHA2
- EPSTI1
- FAM135A
- FAM83B
- FLOT2
- FRS2
- FRS3
- GRB7
- KIDINS220
- KIF14
- PIK3R1
- PIK3R2
- PKP4
- PLEKHG5
- PLXNA1
- PTPN13
- RASAL2
- RBM39
- RBMX
- RHO6
- RND1
- STIP1
- STMN2
- TFRC
- TMEM59
- TXNL1
- UBXN11
- VANGL1
- VANGL2
- WDR6
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Phase I - Functionalization of compounds
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- AADAC
- ABP1
- AHR
- ALDH3A1
- AOC1
- AOC2
- AOC3
- ARNT
- ARNT2
- BPHL
- CBR3
- CES1
- CES2
- CES3
- CMBL
- CYB5B
- CYB5R3
- CYP2B6
- CYP3A28
- CYP3A4
- CYP3A5
- CYP3A74
- DIA1
- EPHX1
- LOC100138645
- MARC2
- MOSC2
- MTARC1
- MTARC2
- NQO2
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Glutathione conjugation
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- AKR1A1
- ESD
- GSTA1
- GSTA2
- GSTA4
- GSTA5
- GSTK1
- GSTM3
- GSTM4
- GSTM5
- GSTO2
- GSTP1
- GSTT1
- HPGDS
- LOC100295687
- MGST1
- MGST2
- MGST3
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Fructose biosynthesis
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PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling
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- AFGF
- AREG
- BDNF
- BTC
- CD19
- CD28
- CD80
- CD86
- EGFR
- EPGN
- ERBB2
- ERBB3
- ERBB4
- EREG
- ERK2
- ESR
- ESR1
- ESR2
- FGF1
- FGF10
- FGF16
- FGF17
- FGF18
- FGF19
- FGF2
- FGF20
- FGF23
- FGF3
- FGF4
- FGF4A
- FGF4C
- FGF5
- FGF5B
- FGF5C
- FGF6
- FGF6A
- FGF7
- FGF7B
- FGF8
- FGF8A
- FGF9
- FGFA
- FGFR1
- FGFR2
- FGFR3
- FGFR4
- FLT3
- FLT3LG
- FRS2
- FYN
- Fgf4
- GAB1
- GAB2
- GRB2
- HBEGF
- HBGF-1
- HGF
- ICOS
- IER3
- IL1RL1
- IL33
- INS
- INSR
- IRAK1
- IRAK4
- IRS1
- IRS2
- KIT
- KITLG
- KL
- KLB
- LCK
- MAPK1
- MAPK3
- MET
- MYD88
- NR3A1
- NR3A2
- NRG1
- NRG2
- NRG3
- NTF3
- NTF4
- NTRK2
- NTRK3
- PDGFA
- PDGFB
- PDGFRA
- PDGFRB
- PIK3AP1
- PIK3CA
- PIK3CB
- PIK3CD
- PIK3R1
- PIK3R2
- PIK3R3
- PIP4K2A
- PIP4K2B
- PIP4K2C
- PIP5K1A
- PIP5K1B
- PIP5K1C
- PIP5K2C
- PPP2CA
- PPP2CB
- PPP2R1A
- PPP2R1B
- PPP2R5A
- PPP2R5B
- PPP2R5D
- PPP2R5E
- PRKM1
- PTPN11
- RAC2
- RHOG
- SCF
- SRC
- STRN
- TGFA
- TRAF6
- TRAT1
- VAV1
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Lewis blood group biosynthesis
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- B3GALT2
- B3GALT4
- B4GALNT2
- FUT10
- FUT11
- FUT2
- FUT4
- FUT6
- FUT7
- FUT9
- SIAT10
- ST3GAL3
- ST3GAL4
- ST3GAL6
- ST6GALNAC6
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Reactions specific to the complex N-glycan synthesis pathway
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- CGA
- CHST10
- CHST8
- FUCA1
- FUT6
- FUT8
- LHB
- MAN2A1
- MAN2A2
- MGAT2
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Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
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- ALG1
- ALG12
- ALG14
- ALG2
- ALG3
- ALG6
- ALG8
- ALG9
- DPAGT1
- LOC107132045
- MPDU1
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N-glycan trimming and elongation in the cis-Golgi
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N-Glycan antennae elongation
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- Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase A
- Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase
- Beta-1,4-galactosyltransferase 1
- Beta-1,4-galactosyltransferase 2
- Beta-1,4-galactosyltransferase
- Beta-1,4-galactosyltransferase
- Beta-1,4-galactosyltransferase
- MGAT4 family member C
- MGAT4B protein
- ST3 beta-galactoside alpha-2,3-sialyltransferase 4
- ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2
- ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3
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- B4GALT1
- B4GALT2
- B4GALT4
- B4GALT5
- B4GALT6
- GALT
- GGTB2
- MGAT4A
- MGAT4B
- MGAT4C
- MGAT5
- ST3GAL4
- ST8SIA2
- ST8SIA3
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Glycogen breakdown (glycogenolysis)
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- AGL
- CALM
- GAA
- GYG1
- GYG2
- PHKA1
- PHKA2
- PHKG2
- PYGL
- PYGM
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COPII-mediated vesicle transport
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- ANKRD28
- AREG
- BET1
- CD59
- CNIH
- CNIH1
- CSNK1D
- CTSC
- CTSZ
- F5
- F8
- FOLR3
- GOLGA2
- GORASP1
- GOSR2
- GRIA1
- HCKID
- LMAN1
- LMAN1L
- LMAN2
- LMAN2L
- MCFD2
- NAPA
- NAPB
- NAPG
- NSF
- PI
- PPP6C
- PPP6R1
- PPP6R3
- PREB
- RAB1A
- RAB1B
- SAPS3
- SAR1B
- SCFD1
- SEC13
- SEC13L1
- SEC16A
- SEC16B
- SEC22A
- SEC22B
- SEC22C
- SEC23A
- SEC23IP
- SEC24A
- SEC24B
- SEC24C
- SEC24D
- SEC31A
- SEC31B
- SERPINA1
- SNAPB
- STX17
- STX5
- TBC1D20
- TFG
- TGFA
- TMED10
- TMP21
- TRAPPC1
- TRAPPC10
- TRAPPC2
- TRAPPC2L
- TRAPPC3
- TRAPPC4
- TRAPPC5
- TRAPPC6A
- TRAPPC6B
- TRAPPC9
- USO1
- VDP
- VIPL
- YKT6
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