GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	November 12, 2024
ECODAB	April 1, 2019

Displaying entries **1976 - 2000** of **2074** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol ▲	Organism	GlyTouCan ID
Defective SLC7A7 causes lysinuric protein intolerance (LPI)	Amino acid transporter heavy chain SLC3A2 Y+L amino acid transporter 1	P08195 Q9UM01	MDU1 SLC3A2 SLC7A7	Homo sapiens (human)
Defective MGAT2 causes CDG-2a	Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase	Q10469	MGAT2	Homo sapiens (human)
MGMT-mediated DNA damage reversal	Methylated-DNA--protein-cysteine methyltransferase	P16455	MGMT	Homo sapiens (human)
Synthesis of IPs in the ER lumen	Multiple inositol polyphosphate phosphatase 1	Q9UNW1	MINPP1 MIPP	Homo sapiens (human)
Defective MMAA causes MMA, cblA type	Methylmalonic aciduria type A protein, mitochondrial Methylmalonyl-CoA mutase, mitochondrial	P22033 Q8IVH4	MMAA MMUT MUT	Homo sapiens (human)
Defective MUT causes MMAM	Methylmalonic aciduria type A protein, mitochondrial Methylmalonyl-CoA mutase, mitochondrial	P22033 Q8IVH4	MMAA MMUT MUT	Homo sapiens (human)
Defective MMAB causes MMA, cblB type	Corrinoid adenosyltransferase MMAB	Q96EY8	MMAB	Homo sapiens (human)
PTEN Loss of Function in Cancer	Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN	P60484	MMAC1 PTEN TEP1	Homo sapiens (human)
Nucleotide catabolism	Deoxynucleoside triphosphate triphosphohydrolase SAMHD1	Q9Y3Z3	MOP5 SAMHD1	Homo sapiens (human)
Opioid Signalling	Mu-type opioid receptor Pro-opiomelanocortin Proenkephalin-B	P01189 P01213 P35372	MOR1 OPRM1 PDYN POMC	Homo sapiens (human)
Defective MPDU1 causes CDG-1f	Mannose-P-dolichol utilization defect 1 protein	O75352	MPDU1	Homo sapiens (human)	G59406KS
PLC-gamma1 signalling	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 Beta-nerve growth factor High affinity nerve growth factor receptor	P01138 P04629 P19174	MTC NGF NGFB NTRK1 PLC1 PLCG1 TRK TRKA	Homo sapiens (human)
TRKA activation by NGF	Beta-nerve growth factor High affinity nerve growth factor receptor	P01138 P04629	MTC NGF NGFB NTRK1 TRK TRKA	Homo sapiens (human)
Defective MTR causes HMAG	Methionine synthase reductase Methionine synthase	Q99707 Q9UBK8	MTR MTRR	Homo sapiens (human)
Defective MTRR causes HMAE	Methionine synthase reductase Methionine synthase	Q99707 Q9UBK8	MTR MTRR	Homo sapiens (human)
MyD88 deficiency (TLR5)	Flagellin Myeloid differentiation primary response protein MyD88 Toll-like receptor 5	O60602 P04949 Q99836	MYD88 TIL3 TLR5 flaF fliC hag	Homo sapiens (human)
Sodium-coupled sulphate, di- and tri-carboxylate transporters	Na(+)/citrate cotransporter Na(+)/dicarboxylate cotransporter 3 Solute carrier family 13 member 1 Solute carrier family 13 member 2 Solute carrier family 13 member 4	Q13183 Q86YT5 Q8WWT9 Q9BZW2 Q9UKG4	NACT NADC1 NADC3 NAS1 NASI1 SDCT1 SDCT2 SLC13A1 SLC13A2 SLC13A3 SLC13A4 SLC13A5 SUT1	Homo sapiens (human)
MPS IIIB - Sanfilippo syndrome B	Alpha-N-acetylglucosaminidase	P54802	NAGLU UFHSD1	Homo sapiens (human)
Defective SLC5A1 causes congenital glucose/galactose malabsorption (GGM)	Sodium/glucose cotransporter 1	P13866	NAGT SGLT1 SLC5A1	Homo sapiens (human)	G58161NS
POU5F1 (OCT4), SOX2, NANOG repress genes related to differentiation	Homeobox protein NANOG POU domain, class 5, transcription factor 1 Transcription factor SOX-2	P48431 Q01860 Q9H9S0	NANOG OCT3 OCT4 OTF3 POU5F1 SOX2	Homo sapiens (human)
Defective SLC6A2 causes orthostatic intolerance (OI)	Sodium-dependent noradrenaline transporter	P23975	NAT1 NET1 SLC6A2 SLC6A5	Homo sapiens (human)
Defective SLC4A4 causes renal tubular acidosis, proximal, with ocular abnormalities and mental retardation (pRTA-OA)	Electrogenic sodium bicarbonate cotransporter 1	Q9Y6R1	NBC NBC1 NBCE1 SLC4A4	Homo sapiens (human)
Defective SLC12A3 causes Gitelman syndrome (GS)	Solute carrier family 12 member 3	P55017	NCC SLC12A3 TSC	Homo sapiens (human)
Defective SLC24A4 causes hypomineralized amelogenesis imperfecta (AI)	Sodium/potassium/calcium exchanger 4	Q8NFF2	NCKX4 SLC24A4	Homo sapiens (human)
Peptide hormone biosynthesis	Neuroendocrine convertase 1 Pro-opiomelanocortin	P01189 P29120	NEC1 PCSK1 POMC	Homo sapiens (human)

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