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MIRAGE
graft-versus-host disease

Summary
Synonym
  • GvHD
  • graft versus host disease
Definition
An immune system disease that is characterized by recognition by mature donor T cells, that contaminate the allogeneic bone marrow, of the recipient's tissue as foreign, causing a severe inflammatory disease characterized by rashes, diarrhea, and liver disease, and that has_material_basis_in an associated with variation in the interleukin-10 gene (IL10) on chromosome 1q32.
Super Class
immune system disease
Disease Ontology
DOID:0081267
Mondo Disease Ontology
MeSH
ORDO
Related Genes
Displaying entries 11 - 13 of 13 in total
Gene ID Gene Symbol Description Source
3588 IL10RB interleukin 10 receptor subunit beta
4288 MKI67 marker of proliferation Ki-67
64127 NOD2 nucleotide binding oligomerization domain containing 2
Related Glycoprotein
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: August 4, 2025