Chagas disease

Summary
Synonym
  • Chagas' disease
  • chagas' disease with digestive system involvement
  • chagas' disease with nervous system involvement
  • chagas' disease with other organ involvement
Definition
A trypanosomiasis that is a tropical parasitic disease caused by the flagellate protozoan Trypanosoma cruzi, which is transmitted to humans and other mammals by an insect vector, the blood-sucking assassin bugs of the subfamily Triatominae (family Reduviidae), most commonly species belonging to the Triatoma, Rhodnius, and Panstrongylus genera. The symptoms include fever, fatigue, body aches, headache, rash, loss of appetite, diarrhea, vomiting, swelling of the eyelids and myocarditis.
Super Class
trypanosomiasis
External Links
Disease Ontology
DOID:12140
Mondo Disease Ontology
MeSH
UMLS
ORDO
GARD
Related Genes
Displaying entries 21 - 30 of 35 in total
Gene ID Gene Symbol Description Source
5291 PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
5293 PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
5294 PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma
5332 PLCB4 phospholipase C beta 4
5553 PRG2 proteoglycan 2, pro eosinophil major basic protein
5743 PTGS2 prostaglandin-endoperoxide synthase 2
6385 SDC4 syndecan 4
6609 SMPD1 sphingomyelin phosphodiesterase 1
6646 SOAT1 sterol O-acyltransferase 1
7167 TPI1 triosephosphate isomerase 1

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: August 19, 2024