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Standards Ontologies Notations
asthma

Summary
Synonym
  • bronchial hyperreactivity
  • chronic obstructive asthma
  • chronic obstructive asthma with acute exacerbation
  • chronic obstructive asthma with status asthmaticus
Definition
A bronchial disease that is characterized by chronic inflammation and narrowing of the airways, which is caused by a combination of environmental and genetic factors. The disease has_symptom recurring periods of wheezing (a whistling sound while breathing), has_symptom chest tightness, has_symptom shortness of breath, has_symptom mucus production and has_symptom coughing.
Super Class
bronchial disease
Disease Ontology
DOID:2841
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
OMIM
GARD
MGI genotype (from TogoID)
Related Genes
Displaying entries 111 - 120 of 206 in total
Gene ID Gene Symbol Description Source
3958 LGALS3 galectin 3
4048 LTA4H leukotriene A4 hydrolase
4049 LTA lymphotoxin alpha
4153 MBL2 mannose binding lectin 2
4210 MEFV MEFV innate immunity regulator, pyrin
4282 MIF macrophage migration inhibitory factor
4318 MMP9 matrix metallopeptidase 9
4353 MPO myeloperoxidase
4582 MUC1 mucin 1, cell surface associated
4583 MUC2 mucin 2, oligomeric mucus/gel-forming
Displaying entries 181 - 190 of 191 in total
Gene ID Gene Symbol Description Source
171284 Timd2 T cell immunoglobulin and mucin domain containing 2
230233 Elp1 elongator complex protein 1
243764 Chrm2 cholinergic receptor, muscarinic 2, cardiac
246256 Fcgr4 Fc receptor, IgG, low affinity IV
246779 Il27 interleukin 27
269109 Dpp10 dipeptidylpeptidase 10
277328 Trpa1 transient receptor potential cation channel, subfamily A, member 1
319239 Npsr1 neuropeptide S receptor 1
329244 Il19 interleukin 19
330496 Ifnl2 interferon lambda 2
Displaying entries 61 - 70 of 112 in total
Gene ID Gene Symbol Description Source
60350 Cd14 CD14 molecule
60422 Slc18a3 solute carrier family 18 member A3
60582 Il1rn interleukin 1 receptor antagonist
63889 Ptgdr prostaglandin D2 receptor
64680 Crhr2 corticotropin releasing hormone receptor 2
64803 P2ry12 purinergic receptor P2Y12
65270 Abo3 histo-blood group ABO system transferase 3
81645 Chrm2 cholinergic receptor, muscarinic 2
81687 Mmp9 matrix metallopeptidase 9
81737 Ntf3 neurotrophin 3
Displaying entries 1 - 10 of 33 in total
Gene ID Gene Symbol Description Source
31926 Idgf4 Imaginal disc growth factor 4
34091 Spn28Dc Serpin 28Dc
34189 Acer Angiotensin-converting enzyme-related
34805 Ance Angiotensin converting enzyme
34978 Idgf1 Imaginal disc growth factor 1
34979 Idgf2 Imaginal disc growth factor 2
34981 Idgf3 Imaginal disc growth factor 3
35334 CarT Carcinine transporter
36417 Balat Beta-alanine transporter
36428 Mdr49 Multi drug resistance 49
Displaying entries 1 - 10 of 20 in total
Gene ID Gene Symbol Description Source
30682 vegfaa vascular endothelial growth factor Aa
58133 ngfb nerve growth factor b (beta polypeptide)
114424 cdh1 cadherin 1, type 1, E-cadherin (epithelial)
387303 gbgt1l4 globoside alpha-1,3-N-acetylgalactosaminyltransferase 1, like 4
394082 slc18a3b solute carrier family 18 member 3b
406411 rhoaa ras homolog gene family, member Aa
406659 rhoac ras homolog gene family, member Ac
436718 rhocb ras homolog family member Cb
447881 gbgt1l3 globoside alpha-1,3-N-acetylgalactosaminyltransferase 1, like 3
554230 kdr kinase insert domain receptor (a type III receptor tyrosine kinase)
Displaying entries 1 - 10 of 14 in total
Gene ID Gene Symbol Description Source Organism
373580 crhr1.2.S corticotropin releasing hormone receptor 1, gene 2 S homeolog Xenopus laevis (African clawed frog)
397750 hmgcr.L 3-hydroxy-3-methylglutaryl-CoA reductase L homeolog Xenopus laevis (African clawed frog)
397778 tgfb1.L transforming growth factor beta 1 L homeolog Xenopus laevis (African clawed frog)
399298 ntf3.L neurotrophin 3 L homeolog Xenopus laevis (African clawed frog)
495825 abo.3.L ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase) L homeolog Xenopus laevis (African clawed frog)
549437 abo.3 ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase) gene 3 Xenopus tropicalis (tropical clawed frog)
549858 abo.2 ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase) gene 2 Xenopus tropicalis (tropical clawed frog)
550054 abo ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase) gene 1 Xenopus tropicalis (tropical clawed frog)
100144634 ace angiotensin I converting enzyme Xenopus tropicalis (tropical clawed frog)
100337618 cdh1.S cadherin 1, type 1 S homeolog Xenopus laevis (African clawed frog)
Displaying entries 1 - 10 of 27 in total
Gene ID Gene Symbol Description Source
172841 45566 Organic cation transporter 1
174044 sma-6 Serine/threonine-protein kinase receptor sma-6
174462 let-23 Receptor tyrosine-protein kinase let-23;receptor protein-tyrosine kinase
175182 ver-1 Protein ver-1
175383 zmp-2 Matrix metalloproteinase-B
175504 pat-3 Integrin beta pat-3
177343 skn-1 BZIP domain-containing protein;Protein skinhead-1
178118 trpa-1 Ion transport domain-containing protein;Transient receptor potential cation channel subfamily A member 1 homolog
178215 pgp-1 Multidrug resistance protein pgp-1
178274 cho-1 High-affinity choline transporter 1
Displaying all 8 entries
Gene ID Gene Symbol Description Source
850462 GIT1 Git1p
851171 HMG2 hydroxymethylglutaryl-CoA reductase (NADPH) HMG2
851977 CTS2 putative chitinase
853671 STE6 ATP-binding cassette a-factor transporter STE6
853978 NFT1 putative multidrug transporter NFT1
854394 STE13 Ste13p
854900 HMG1 hydroxymethylglutaryl-CoA reductase (NADPH) HMG1
856294 RHO1 Rho family GTPase RHO1
The Human Phenotype Ontology
Displaying all 3 entries
HPO ID HPO Term
HP:0001426 Non-Mendelian inheritance
HP:0000006 Autosomal dominant inheritance
HP:0002099 Asthma
Displaying 1 entry
Gene ID Gene Symbol Description
240 ALOX5 arachidonate 5-lipoxygenase
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 9, 2024