glioblastoma

Summary
Synonym
  • GBM
  • adult glioblastoma multiforme
  • glioblastoma multiforme
  • grade IV adult Astrocytic tumor
  • primary glioblastoma multiforme
  • spongioblastoma multiforme
Definition
A malignant astrocytoma characterized by the presence of small areas of necrotizing tissue that is surrounded by anaplastic cells as well as the presence of hyperplastic blood vessels, and that has_material_basis_in abnormally proliferating cells derives_from multiple cell types including astrocytes and oligondroctyes.
Super Class
malignant astrocytoma
Disease Ontology
DOID:3068
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
GARD
MGI genotype (from TogoID)
WikiPathways (from TogoID)
Related Genes
Displaying entries 11 - 20 of 54 in total
Gene ID Gene Symbol Description Source
2146 EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit
2323 FLT3LG fms related receptor tyrosine kinase 3 ligand
3265 HRAS HRas proto-oncogene, GTPase
3371 TNC tenascin C
3417 IDH1 isocitrate dehydrogenase (NADP(+)) 1
3603 IL16 interleukin 16
3747 KCNC2 potassium voltage-gated channel subfamily C member 2
3791 KDR kinase insert domain receptor
3845 KRAS KRAS proto-oncogene, GTPase
3897 L1CAM L1 cell adhesion molecule
Displaying entries 11 - 20 of 38 in total
Gene ID Gene Symbol Description Source
15926 Idh1 isocitrate dehydrogenase 1 (NADP+), soluble
16170 Il16 interleukin 16
16542 Kdr kinase insert domain protein receptor
16653 Kras Kirsten rat sarcoma viral oncogene homolog
16728 L1cam L1 cell adhesion molecule
17390 Mmp2 matrix metallopeptidase 2
17395 Mmp9 matrix metallopeptidase 9
18591 Pdgfb platelet derived growth factor, B polypeptide
18596 Pdgfrb platelet derived growth factor receptor, beta polypeptide
18605 Enpp1 ectonucleotide pyrophosphatase/phosphodiesterase 1
Displaying entries 21 - 24 of 24 in total
Gene ID Gene Symbol Description Source
170568 Dmbt1 deleted in malignant brain tumors 1
246153 Kcnc2 potassium voltage-gated channel subfamily C member 2
295703 Serping1 serpin family G member 1
362931 Adgrb1 adhesion G protein-coupled receptor B1
Displaying entries 1 - 10 of 13 in total
Gene ID Gene Symbol Description Source
31792 Nrg Neuroglian
31926 Idgf4 Imaginal disc growth factor 4
32115 Ptp10D Protein tyrosine phosphatase 10D
33599 Shaw Shaker cognate w
34091 Spn28Dc Serpin 28Dc
34978 Idgf1 Imaginal disc growth factor 1
34979 Idgf2 Imaginal disc growth factor 2
34981 Idgf3 Imaginal disc growth factor 3
35717 tor torso
35846 Cirl Calcium-independent receptor for alpha-latrotoxin
Displaying 1 entry
Gene ID Gene Symbol Description Source
554230 kdr kinase insert domain receptor (a type III receptor tyrosine kinase)
Displaying entries 1 - 10 of 14 in total
Gene ID Gene Symbol Description Source
174437 dep-1 Receptor-type tyrosine-protein phosphatase dep-1
175182 ver-1 Protein ver-1
177078 lad-2 Ig-like domain-containing protein;Neuroglian
177940 egl-21 Carboxypeptidase E
179053 cpr-4 Cathepsin B-like cysteine proteinase 4
179663 enpp-1 Ectonucleotide pyrophosphatase/phosphodiesterase C27A7.1;NUC domain-containing protein
179665 C27A7.3 Ectonucleotide pyrophosphatase/phosphodiesterase C27A7.1;Ectonucleotide pyrophosphatase/phosphodiesterase C27A7.3
179991 zmp-4 Hemopexin;Peptidase metallopeptidase domain-containing protein
180033 cpr-3 Cathepsin B-like cysteine proteinase 3
180351 W01F3.2 Uncharacterized protein
Displaying all 7 entries
Gene ID Gene Symbol Description Source
850391 NPP1 nucleotide diphosphatase/phosphodiesterase NPP1
850871 IDP2 isocitrate dehydrogenase (NADP(+)) IDP2
851493 IDP1 isocitrate dehydrogenase (NADP(+)) IDP1
851977 CTS2 putative chitinase
853313 PBS2 mitogen-activated protein kinase kinase PBS2
855723 IDP3 isocitrate dehydrogenase (NADP(+)) IDP3
856699 NPP2 nucleotide diphosphatase/phosphodiesterase NPP2

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Last updated: December 9, 2024