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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
amyotrophic lateral sclerosis
Summary
- Synonym
-
- ALS
- Lou Gehrig's disease
- motor neuron disease, bulbar
- Definition
- A motor neuron disease that is characterized by muscle spasticity, rapidly progressive weakness due to muscle atrophy, difficulty in speaking, swallowing, and breathing.
- Super Class
- motor neuron disease
Related Genes
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 3482 | IGF2R | insulin like growth factor 2 receptor | |
| 3700 | ITIH4 | inter-alpha-trypsin inhibitor heavy chain 4 | |
| 3709 | ITPR2 | inositol 1,4,5-trisphosphate receptor type 2 | |
| 3791 | KDR | kinase insert domain receptor | |
| 3934 | LCN2 | lipocalin 2 | |
| 4134 | MAP4 | microtubule associated protein 4 | |
| 4137 | MAPT | microtubule associated protein tau | |
| 4312 | MMP1 | matrix metallopeptidase 1 | |
| 4313 | MMP2 | matrix metallopeptidase 2 | |
| 4318 | MMP9 | matrix metallopeptidase 9 |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 11829 | Aqp4 | aquaporin 4 | |
| 12266 | C3 | complement component 3 | |
| 12273 | C5ar1 | complement component 5a receptor 1 | |
| 12371 | Casp9 | caspase 9 | |
| 13191 | Dctn1 | dynactin 1 | |
| 13483 | Dpp6 | dipeptidylpeptidase 6 | |
| 13856 | Epo | erythropoietin | |
| 14030 | Ewsr1 | Ewing sarcoma breakpoint region 1 | |
| 14573 | Gdnf | glial cell line derived neurotrophic factor | |
| 14718 | Got1 | glutamic-oxaloacetic transaminase 1, soluble |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 25715 | Slc11a2 | solute carrier family 11 member 2 | |
| 25718 | Igf1r | insulin-like growth factor 1 receptor | |
| 29143 | Grn | granulin precursor | |
| 29152 | Mstn | myostatin | |
| 29167 | Dctn1 | dynactin subunit 1 | |
| 29272 | Dpp6 | dipeptidyl peptidase like 6 | |
| 29482 | Slc1a2 | solute carrier family 1 member 2 | |
| 29527 | Ptgs2 | prostaglandin-endoperoxide synthase 2 | |
| 50686 | Gsk3a | glycogen synthase kinase 3 alpha | |
| 81686 | Mmp2 | matrix metallopeptidase 2 |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 31248 | sgg | shaggy | |
| 36232 | Sod3 | Superoxide dismutase 3 | |
| 38657 | vn | vein | |
| 38895 | Sarm | Sterile alpha and Armadillo motif | |
| 42490 | Mvl | Malvolio | |
| 42549 | InR | Insulin-like receptor | |
| 43223 | Lerp | lysosomal enzyme receptor protein | |
| 43469 | Ptp99A | Protein tyrosine phosphatase 99A | |
| 44811 | E(bx) | Enhancer of bithorax |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 30682 | vegfaa | vascular endothelial growth factor Aa | |
| 403143 | sarm1 | sterile alpha and TIR motif containing 1 | |
| 447803 | pon1 | paraoxonase 1 | |
| 554230 | kdr | kinase insert domain receptor (a type III receptor tyrosine kinase) | |
| 798441 | mstnb | myostatin b | |
| 100004455 | epoa | erythropoietin a |
| Gene ID | Gene Symbol | Description | Source | Organism |
|---|---|---|---|---|
| 380341 | pon2.L | paraoxonase 2 L homeolog | Xenopus laevis (African clawed frog) | |
| 432039 | pon2.S | paraoxonase 2 S homeolog | Xenopus laevis (African clawed frog) | |
| 448598 | pon2 | paraoxonase 2 | Xenopus tropicalis (tropical clawed frog) | |
| 779087 | gdnf.L | glial cell derived neurotrophic factor L homeolog | Xenopus laevis (African clawed frog) |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 180351 | W01F3.2 | Uncharacterized protein | |
| 180641 | glt-1 | Excitatory amino acid transporter | |
| 180939 | smf-1 | NRAMP-like transporter smf-1 | |
| 181723 | hda-4 | Histone deacetylase 4 | |
| 186632 | ver-4 | Tyrosine-protein kinase receptor ver-4 | |
| 187297 | poml-1 | PON (paraoxonase) and MEC-6 Like | |
| 187623 | glt-6 | Putative sodium-dependent excitatory amino acid transporter glt-6 | |
| 191766 | smf-2 | NRAMP-like transporter smf-2 |
