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Standards Ontologies Notations
amyotrophic lateral sclerosis

Summary
Synonym
  • ALS
  • Lou Gehrig's disease
  • motor neuron disease, bulbar
Definition
A motor neuron disease that is characterized by muscle spasticity, rapidly progressive weakness due to muscle atrophy, difficulty in speaking, swallowing, and breathing.
Super Class
motor neuron disease
External Links
Disease Ontology
DOID:332
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
ORDO
OMIM
GARD
MGI genotype (from TogoID)
WikiPathways (from TogoID)
Related Genes
Displaying entries 1 - 10 of 100 in total
Gene ID Gene Symbol Description Source
39 ACAT2 acetyl-CoA acetyltransferase 2
43 ACHE acetylcholinesterase (Yt blood group)
128 ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide
142 PARP1 poly(ADP-ribose) polymerase 1
240 ALOX5 arachidonate 5-lipoxygenase
246 ALOX15 arachidonate 15-lipoxygenase
250 ALPP alkaline phosphatase, placental
353 APRT adenine phosphoribosyltransferase
811 CALR calreticulin
847 CAT catalase
Displaying all 7 entries
Gene ID Gene Symbol Description Source
14718 Got1 glutamic-oxaloacetic transaminase 1, soluble
15289 Hmgb1 high mobility group box 1
18654 Pgf placental growth factor
19017 Ppargc1a peroxisome proliferative activated receptor, gamma, coactivator 1 alpha
56637 Gsk3b glycogen synthase kinase 3 beta
237868 Sarm1 sterile alpha and HEAT/Armadillo motif containing 1
606496 Gsk3a glycogen synthase kinase 3 alpha
Displaying all 7 entries
Gene ID Gene Symbol Description Source
24401 Got1 glutamic-oxaloacetic transaminase 1
25459 Hmgb1 high mobility group box 1
50686 Gsk3a glycogen synthase kinase 3 alpha
83516 Ppargc1a PPARG coactivator 1 alpha
84027 Gsk3b glycogen synthase kinase 3 beta
94203 Pgf placental growth factor
287545 Sarm1 sterile alpha and TIR motif containing 1
Displaying all 3 entries
Gene ID Gene Symbol Description Source
31248 sgg shaggy
38895 Sarm Sterile alpha and Armadillo motif
43223 Lerp lysosomal enzyme receptor protein
Displaying 1 entry
Gene ID Gene Symbol Description Source
403143 sarm1 sterile alpha and TIR motif containing 1
Displaying 1 entry
Gene ID Gene Symbol Description Source
175502 tir-1 ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase;NAD(+) hydrolase tir-1;Sterile alpha and TIR motif-containing protein 1
Related Glycoprotein
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: August 19, 2024