systemic scleroderma

Summary
Synonym
  • Scleroderma
  • Scleroderma syndrome
  • progressive systemic sclerosis
  • systemic sclerosis
Definition
A scleroderma that is characterized by fibrosis (or hardening) of the skin and major organs, as well as vascular alterations, and autoantibodies.
Super Class
scleroderma
Disease Ontology
DOID:418
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
OMIM
GARD
MGI genotype (from TogoID)
Related Genes
Displaying entries 31 - 40 of 66 in total
Gene ID Gene Symbol Description Source
3486 IGFBP3 insulin like growth factor binding protein 3
3554 IL1R1 interleukin 1 receptor type 1
3558 IL2 interleukin 2
3565 IL4 interleukin 4
3569 IL6 interleukin 6
3596 IL13 interleukin 13
3597 IL13RA1 interleukin 13 receptor subunit alpha 1
3605 IL17A interleukin 17A
3791 KDR kinase insert domain receptor
4049 LTA lymphotoxin alpha
Displaying entries 51 - 57 of 57 in total
Gene ID Gene Symbol Description Source
56744 Pf4 platelet factor 4
80901 Cxcr6 C-X-C motif chemokine receptor 6
83964 Jam3 junction adhesion molecule 3
83995 Mmp1a matrix metallopeptidase 1a (interstitial collagenase)
209590 Il23r interleukin 23 receptor
246779 Il27 interleukin 27
279028 Adamts13 ADAM metallopeptidase with thrombospondin type 1 motif 13
Displaying entries 11 - 20 of 36 in total
Gene ID Gene Symbol Description Source
25008 Lta lymphotoxin alpha
25459 Hmgb1 high mobility group box 1
25464 Icam1 intercellular adhesion molecule 1
25589 Kdr kinase insert domain receptor
25703 Rbp4 retinol binding protein 4
25712 Ifng interferon gamma
29360 Selenop selenoprotein P
29393 Col1a1 collagen type I alpha 1 chain
29527 Ptgs2 prostaglandin-endoperoxide synthase 2
29583 Pecam1 platelet and endothelial cell adhesion molecule 1
Displaying all 10 entries
Gene ID Gene Symbol Description Source
31926 Idgf4 Imaginal disc growth factor 4
34091 Spn28Dc Serpin 28Dc
34189 Acer Angiotensin-converting enzyme-related
34805 Ance Angiotensin converting enzyme
34978 Idgf1 Imaginal disc growth factor 1
34979 Idgf2 Imaginal disc growth factor 2
34981 Idgf3 Imaginal disc growth factor 3
36868 Idgf6 Imaginal disc growth factor 6
37104 Idgf5 Imaginal disc growth factor 5
42490 Mvl Malvolio
Displaying all 5 entries
Gene ID Gene Symbol Description Source
30682 vegfaa vascular endothelial growth factor Aa
58133 ngfb nerve growth factor b (beta polypeptide)
554230 kdr kinase insert domain receptor (a type III receptor tyrosine kinase)
565980 ace angiotensin I converting enzyme (peptidyl-dipeptidase A) 1
791973 cxcr3.2 chemokine (C-X-C motif) receptor 3, tandem duplicate 2
Displaying all 2 entries
Gene ID Gene Symbol Description Source Organism
100144634 ace angiotensin I converting enzyme Xenopus tropicalis (tropical clawed frog)
108709389 ngf.S nerve growth factor S homeolog Xenopus laevis (African clawed frog)
Displaying entries 1 - 10 of 18 in total
Gene ID Gene Symbol Description Source
174044 sma-6 Serine/threonine-protein kinase receptor sma-6
175182 ver-1 Protein ver-1
176076 fbn-1 EGF-like domain-containing protein
176282 lin-12 lin-12/Notch intracellular domain
176286 glp-1 glp-1/Notch intracellular domain
176829 daf-1 Cell surface receptor daf-1
177044 smf-3 NRAMP-like transporter smf-3
178672 srp-3 Serpin domain-containing protein
178748 zmp-3 Matrix metalloproteinase-C
179991 zmp-4 Hemopexin;Peptidase metallopeptidase domain-containing protein
Displaying all 2 entries
Gene ID Gene Symbol Description Source
850721 SMF3 putative divalent metal ion transporter SMF3
851977 CTS2 putative chitinase

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Last updated: December 9, 2024